Early initiation of SGLT2 inhibitors in acute myocardial infarction and cardiovascular outcomes, an updated systematic review and meta-analysis by Davood Semirani-Nezhad, Hamidreza Soleimani, Morvarid Taebi, Khatere Roozbehi, Soodeh Jahangiri, Babak Sattartabar, Fatemeh Takaloo, Bahar parastooei, Erfan Asfa, Danyal Salabat, Mohammad Mobin Alishahi, Fatemeh Mosayebi, Yaser jenab, Rahul Gupta, Toshiki Kuno, Wilbert Aronow, Kaveh Hosseini

“…Abstract Background Sodium-glucose cotransporter-2 (SGLT2) inhibitors increase survival rate in heart failure, but early initiation of these agents after acute myocardial infarction (MI) is controversial. …”
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Building of CuO₂@Cu-TA@DSF/DHA Nanoparticle Targets MAPK Pathway to Achieve Synergetic Chemotherapy and Chemodynamic for Pancreatic Cancer Cells by Jiaru Zhang, Zuoping Li, Zhenzhen Xie, Shiwan You, Yanbing Chen, Yuling Zhang, Jing Zhang, Na Zhao, Xiling Deng, Shiguo Sun

“…<b>Background/Objectives:</b> With the increase of reactive oxygen species (ROS) production, cancer cells can avoid cell death and damage by up-regulating antioxidant programs. …”
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Nutritional status and systemic inflammation in COPD: prognostic value of the advanced lung cancer inflammation index by Jun Yao, Peng Wu, Zhishu Li, Lingyan Zhao, Ziqiao Fu, Ping Shi, Xiaomin Xiong, Xuping Chen, Bin Yu, Yan He, Tong Feng, Jia Zeng, Ran Duan, Ran Duan

“…BackgroundChronic Obstructive Pulmonary Disease (COPD) is a leading cause of global mortality, with systemic inflammation and malnutrition playing pivotal roles in its progression and outcomes. …”
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Prognostic value of the ratio between right ventricular free wall longitudinal strain and systolic pulmonary artery pressure in patients with heart failure with reduced ejection fr... by Călin-Dinu Hădăreanu, Călin-Dinu Hădăreanu, Diana-Ruxandra Hădăreanu, Diana-Ruxandra Hădăreanu, Despina-Manuela Toader, Maria-Livia Iovănescu, Maria-Livia Iovănescu, Cristina Florescu, Cristina Florescu, Victor-Cornel Raicea, Victor-Cornel Raicea, Ionuț Donoiu, Ionuț Donoiu

“…Non-invasive indices of RV–pulmonary artery (RVPA) coupling may offer enhanced prognostic value.MethodsWe retrospectively evaluated advanced echocardiographic surrogates of RVPA coupling in 104 HFrEF patients with V-sMR.ResultsOver a median follow-up of 526 days, 48 patients (46.2%) reached the composite endpoint of rehospitalization for HF decompensation or all-cause mortality. …”
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Prognostic role of pre-procedural lung ultrasound in patients undergoing transcatheter aortic valve implantation by Guilherme Pinheiro Machado, Pedro Castilhos de Freitas Crivelaro, Gustavo Neves de Araujo, Guilherme Heiden Telo, Luiz Carlos Corsetti Bergoli, Marina Petersen Saadi, Julia Carvalho da Silva, Camila Porto Cardoso, Wagner Azevedo, Felipe Costa Fuchs, Marco Wainstein

“…BackgroundTranscatheter aortic valve implantation (TAVI) is the preferred treatment for patients with severe aortic stenosis (AS) in patients &gt;75 years. …”
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Thermoplastic Zinc-Infused Polymer for Chairside Socket Seal Abutments Enhances Antimicrobial and Tissue-Integrative Properties by Wannes Van Holm, Katleen Vandamme, Jill Hadisurya, Ferda Pamuk, Naiera Zayed, Merve Kübra Aktan, Annabel Braem, Andy Temmerman, Wim Teughels

“…The present study investigated a novel Zn-containing polymer for its potential in soft-tissue engineering applications. <b>Methods</b>: Four traditional materials—titanium, glass ionomer, a composite, and the novel Zn-containing polymer—were tested in vitro for bacterial growth using a multispecies oral bacterial model compared to hydroxyapatite. …”
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Relationship between kidney function and healthy life expectancy: A historical cohort study by Hisayuki Ogura, Tadashi Toyama, Hikaru Samuta, Kohei Hirako, Tomoya Itatani, Shiori Nakagawa, Megumi Oshima, Shinji Kitajima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Tomoyuki Takura, Takashi Wada, Yasunori Iwata

“…Abstract Background The impact of chronic kidney disease (CKD) on healthy life expectancy and healthcare costs requires research. …”
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Associations of frailty and cognitive impairment with all-cause and cardiovascular mortality in older adults: a prospective cohort study from NHANES 2011–2014 by An-Bang Liu, Yan-Xia Lin, Guan-Ying Li, Ting-Ting Meng, Peng Tian, Jian-Lin Chen, Xin-He Zhang, Wei-Hong Xu, Yu Zhang, Dan Zhang, Yan Zheng

“…Abstract Background The global aging trend exacerbates the challenge of frailty and cognitive impairment in older adults, yet their combined impact on health outcomes remains under-investigated. …”
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Reduced sensitivity to thyroid hormones is associated with differentiated thyroid cancer in the euthyroid thyroidectomy population by Huaijin Xu, Huaijin Xu, Hongzhou Liu, Xiaodong Hu, Xiaomeng Jia, Zhe Xue, Anning Wang, Shaoyang Kang, Shaoyang Kang, Zhaohui Lyu, Zhaohui Lyu

“…BackgroundThe inconclusive associations between thyroid-related hormones and differentiated thyroid cancer (DTC) suggest complex pathophysiologic processes, for which thyroid hormone sensitivity may provide new insights.MethodsWe retrospectively analyzed preoperative clinical data and postoperative pathological data of 9,515 euthyroid adults who underwent thyroidectomy for thyroid nodules pathologically confirmed as benign nodules or DTC. …”
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Intraoperative hemodynamics in prediction of postoperative kidney injury after type a aortic dissection surgery: a retrospective cohort study by Lihai Chen, Yi Cheng, Xinyi Bu, Chen Zhang, Jie Sun, Xuesheng Liu, Siyu Kong, Yali Ge, Hongwei Shi, Jifang Zhou

“…Background Type A aortic dissection (TAAD) is a severe cardiovascular condition associated with high risks for postoperative complications, particularly renal dysfunction. …”
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Impact of triglyceride glucose-weight adjusted waist index and its cumulative exposure on stroke risk: a nationwide prospective cohort study by Shiming He, Yinghao Kuang, Xinfang Huang, Yafei Jian, Jinyan Zhang, Wanfen Huang, Yang Zou, Guotai Sheng, Wei Wang, Hongyi Yang

“…Abstract Background Insulin resistance and obesity are significant factors contributing to the incidence of stroke. …”
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Macroscopic Evaluation of Poly(3-hydroxybutyrate-co-3-hydroxy valerate), PHBV-Based Nanofiber Scaffolds with Aloe Vera or Honey in Murine Wound Healing by José Manuel Pérez-Galván, José Enrique Hernández-Rodríguez, José Luis Martín-Barrasa, Maximina Monzón-Mayor, Pedro Saavedra-Santana, María del Mar Romero-Alemán

“…<b>Background/Objectives</b>: The utility of various biocompatible biological and synthetic polymers as substrates to provide structural support, facilitate cell migration, and promote the healing of full-thickness wounds by secondary intention has been studied. …”
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Estimated potassium intake and major adverse cardiovascular events in individuals with type 2 diabetes: a prospective cohort study with trans-ethnic validation by Jian-Jun Liu, Huili Zheng, Sylvia Liu, Tsz Kiu Kwan, Resham L. Gurung, Clara Chan, Janus Lee, Keven Ang, Joe de Keizer, Samy Hadjadj, Pierre-Jean Saulnier, Mary F. F. Chong, Su Chi Lim

“…Abstract Background Data on the relationship between potassium intake and major cardiovascular events (MACE) in patients with diabetes are scarce. …”
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Prolonging calcineurin inhibitor therapy post kidney allograft failure: a prospective study by Rita Leal, Pedro Fragoso, João Venda, José Gomes, Maria Inácio, Maria Guedes Marques, Luís Rodrigues, Lídia Santos, Catarina Romãozinho, Francisco Caramelo, Helena Oliveira Sá, António Martinho, Arnaldo Figueiredo, Rui Alves

“…Background The optimal immunosuppressive (IS) withdrawal strategy after kidney allograft failure remains unclear. …”
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Genomic features of carbapenem-resistant Klebsiella pneumoniae isolated in French Polynesia and description of a novel transposon Tn7722 responsible for NDM-1 dissemination by Huynh Ngoc Tram Vo, Aicha Hamieh, Marc Levy, Pierre Pontarotti, Jean Marc Rolain, Vicky Merhej

“…METHODS: Whole-genome sequencing using Miseq and Nanopore technologies and computational analysis of 17 CRKP strains were performed. …”
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Physical activity and mortality in the general population with and without major depression by Vagner Deuel de O. Tavares, Jeanne V. A. Williams, Vandad Sharifi, Andrew Bulloch, Gina Dimitropoulos, Nicole Leite Galvão-Coelho, Scott Patten

“… Background and aims: It is not yet well understood whether physical activity (PA) may protect against elevated mortality in major depression. …”
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Current treatment status of fabry disease in South Korea: a longitudinal National health insurance service data-based study by DoHyeon Lee, Samel Park, Hyejin Yu, Eunjung Cho, Seung Seok Han, Eun Sil Koh, Byung Ha Chung, Kyung Hwan Jeong, Soo Jeong Choi, Eun Young Lee, Su Hyun Kim, Eun Hui Bae, Sunyong Yoo, Young Joo Kwon

“…Abstract Background Fabry disease (FD) is an X-linked lysosomal storage disease caused by a mutation of the gene that encodes the α-galactosidase A enzyme. …”
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Clinical Outcomes According to Aortic Stenosis Management: Insights From Real‐World Practice by Augustin Coisne, David Montaigne, Samy Aghezzaf, Sandro Ninni, Gilles Lemesle, Arnaud Sudre, Nicolas Lamblin, Thomas Modine, André Vincentelli, Francis Juthier, Martin B. Leon, Juan F. Granada, Christophe Bauters

“…Background Real‐world data regarding clinical outcomes according to aortic stenosis (AS) management are scarce. …”
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“Impact of regional data reporting and feedback on rectal cancer surgery quality metrics in the Surgical Care Outcomes Assessment Program (SCOAP)” by Alex J. Charboneau, MD, MS, Chad Cragle, MD, PhD, Joseph Frankhouse, MD, Shalini Kanneganti, MD, Jenny A. Kaplan, MD, Ravi Moonka, MD, Laila Rashidi, MD, Vlad V. Simianu, MD, MPH

“…Background: Management of rectal cancer is increasingly complex. …”
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Prognostic Value of Biomarkers in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy by Christopher Mann, MD, Ulrike Pailer, MSc, Andreas Spannbauer, MD, Fardin Hamidi, MD, Aliza Veronika Braser, Martin Hülsmann, MD, Christian Gerges, MD, PhD, Michael Gottsauner-Wolf, MD, Mariann Gyöngyösi, MD, Markus Raderer, MD, Martin Riesenhuber, MD, PhD, Christian Hengstenberg, MD, Jutta Bergler-Klein, MD, Thomas A. Zelniker, MD, MSc

“…Background: Immune checkpoint inhibitors (ICIs) have improved outcomes for several malignancies, but cancer patients face an increased risk of cardiovascular disease due to shared risk factors, similar biological mechanisms, and cardiotoxic side effects of therapy. …”
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