Internal-External Homologous Drug-Loaded Exosome-Like Nanovesicles Released from Semi-IPN Hydrogel Enhancing Wound Healing of Chemoradiotherapy-Induced Oral Mucositis by Wei X, Wang M, Dong X, He Y, Nan W, Ji S, Zhao M, Chang H, Wei H, Ding D, Chen H

“…This study aimed to develop a novel therapeutic approach.Methods: We fabricated internally-externally homologous drug-loaded exosome-like nanovesicles (ORI/ENs) derived from Rabdosia rubescens and encapsulated them in a semi-interpenetrating network hydrogel system (ORI/ENs/Gel) to repair chemoradiotherapy-induced OM. …”
Get full text

Does the Relationship of the Autonomic Symptoms Questionnaire COMPASS 31 with Cardiovascular Autonomic Tests Differ between Type 1 and Type 2 Diabetes Mellitus? by Ilenia D’Ippolito, Marika Menduni, Cinzia D’Amato, Aikaterini Andreadi, Davide Lauro, Vincenza Spallone

“…Background The aim was to investigate if autonomic symptoms questionnaire Composite Autonomic Symptom Score (COMPASS) 31 has different association with cardiovascular autonomic neuropathy (CAN) and diagnostic performance between type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). …”
Get full text

Modified Naples Prognostic Score for Postoperative Prognostic Stratification in Patients with Oral Squamous Cell Carcinoma by Ran J, Liu Y, Yi X, Zhang F

“…Jingyi Ran, Yalian Liu, Xiaoxi Yi, Fujun Zhang Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Fujun Zhang, Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China, Email cnzfj@cqmu.edu.cnBackground: The Naples Prognostic Score (NPS) is a composite index that combines serum albumin (ALB), total cholesterol (TC), neutrophil-to-lymphocyte ratio (NLR), and lymphocyte-to-monocyte ratio (LMR). …”
Get full text

Effectiveness of Cognitive Remediation Interventions for Schizophrenia in Asian Population: A Systematic Review and Meta-analysis of Randomized Controlled Trials by Suvarna Jyothi Kantipudi, Pratiksha Venkatasubramanian, Ranganath Rattehalli

“…Background: Cognitive deficits are an integral part of schizophrenia, with negatively impacting functionality. …”
Get full text

Body mass index and critical care outcomes in hospitalized COVID-19 patients-A national cohort study. by Yolanda Bonilla, Daniel High, Jose Acosta Rullan, Jude Tabba, Richard Shalmiyev, Tanner Noris, Andrea Folds, Ana Martinez, Daniel Heller, Raiko Diaz, Siddarth Kathuria, Prerna Sharma, Mauricio Danckers

“…<h4>Background</h4>The COVID-19 pandemic caused significant global mortality. …”
Get full text

Impact of implant abutment materials on force damping response and marginal fit of implant supported restoration by Amr Mohammed Hussein Elmesery, Amany Mohammed Korsel, Waleed Elshahawy

“…Abstract Background The marginal fit and force-damping response of implant-supported restorations play critical roles in the long-term success of dental implants. …”
Get full text

Combined impact of prediabetes and fatty liver index on cardiometabolic outcomes and mortality in middle aged adults: a nationwide cohort study by Young Sang Lyu, Minae Park, Hee Kyung Kim, Sojeong Park, Ji Yong Park, A Ram Hong, Jee Hee Yoon, Seogsong Jeong, Youngmin Yoon, Jin Hwa Kim, Sang Yong Kim, Ho-Cheol Kang, Wonsuk Choi

“…Abstract Background To investigate the combined effect of prediabetes and fatty liver index on incident diabetes (DM), major adverse cardiovascular events (MACE), and mortality in middle-aged adults. …”
Get full text

Fracture resistance of milled and 3D printed ultra-thin occlusal veneers made of CAD/CAM resin-based ceramics cemented by variable luting approaches by Ali A. Elkaffas, Abdullah Alshehri, Abdullah Ali Alqahtani, Abdulellah F. Almudahi, Khalid K. Alanazi, Feras Abdulqader Alhalabi, Mohammed Ali Abuelqomsan, Ali R. Alqahtani

“…Abstract Background Pathological tooth wear is becoming an increasingly serious societal issue. …”
Get full text

Oxidised low-density lipoprotein and adverse outcome in patients with acute mild ischaemic stroke or high-risk TIA: a secondary analysis of the INSPIRES randomised clinical trial by Yilong Wang, Weiqi Chen, Yuesong Pan, Tingting Wang, Xiaotong Li, Hongyi Yan, Guojun Zhang, Lingling Jiang, Yuxin Chen, Yaowei Ding

“…Background Research data regarding the correlation between elevated oxidised low-density lipoprotein (oxLDL) cholesterol concentrations and unfavourable clinical outcomes in individuals experiencing minor acute ischaemic cerebrovascular events or transient ischaemic attack (TIA) with presumed atherosclerotic aetiology are still limited.Methods This investigation incorporated a cohort of 5814 participants derived from the Intensive Statin and Antiplatelet Therapy for Acute High-Risk Intracranial or Extracranial Atherosclerosis clinical trial. …”
Get full text

Association between lower geriatric nutritional risk index and low cognitive functions in United States older adults: a cross-sectional study by Jiuling Liu, Melysze Deanne Oorloff, Adithya Nadella, Ning Zhou, Min Ye, Yifeng Tang, Yuanwei Wang

“…BackgroundWe aimed to explore the association between the Geriatric Nutritional Risk Index (GNRI) and the risk of low cognitive functions among older adults in the United States (US).MethodsUtilizing data from the National Health and Nutrition Examination Study (NHANES) database, a cross-sectional analysis was conducted. …”
Get full text

Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): statistical analysis plan for a randomised controlled trial by Norin Ahmed, Hakim-Moulay Dehbi, Nick Freemantle, Jonathan Best, Philip S. Nash, James K. Ruffle, David Doig, David J. Werring

“…Abstract Background Atrial fibrillation causes one-fifth of ischaemic strokes, with a high risk of early recurrence. …”
Get full text

Prognostic Value of Epicardial Adipose Tissue in Heart Failure With Mid‐Range and Preserved Ejection Fraction: A Multicenter Study by Wenxian Wang, Yan Gao, Jian Wang, Congshan Ji, Hui Gu, Xianshun Yuan, Shifeng Yang, Ximing Wang

“…Background Epicardial adipose tissue (EAT) accumulation is thought to play a role in the pathophysiology of heart failure (HF) with mid‐range ejection fraction and HF with preserved ejection fraction, but its effect on outcome is unknown. …”
Get full text

Chromatin Phenotype Karyometry Can Predict Recurrence in Papillary Urothelial Neoplasms of Low Malignant Potential by Rodolfo Montironi, Marina Scarpelli, Antonio Lopez-Beltran, Roberta Mazzucchelli, David Alberts, James Ranger-Moore, Hubert G. Bartels, Peter W. Hamilton, Janine Einspahr, Peter H. Bartels

“…Background: A preceding exploratory study (J. Clin. …”
Get full text

Impact on Patient Outcomes of Continuous Vital Sign Monitoring on Medical Wards: Propensity-Matched Analysis by Bradley Rowland, Amit Saha, Vida Motamedi, Richa Bundy, Scott Winsor, Daniel McNavish, William Lippert, Ashish K Khanna

“… BackgroundContinuous and wireless vital sign (VS) monitoring on hospital wards is superior to intermittent VS monitoring at detecting VS abnormalities; however, the impact on clinical outcomes remains to be confirmed. …”
Get full text

Relationship between multidimensional sleep health and depression during late pregnancy: a cross-sectional study by Yueying Wang, Jinle Wang, Pei Chen, Jiahui Zhang, Qin Lin, Bilgay Izci-Balserk, Yan Li, Bei Bei, Bingqian Zhu

“…Abstract Background Depression is common among pregnant women and identifying modifiable risk factors is critical (e.g., sleep). …”
Get full text

Effects of Nontraditional Division III Lacrosse Participation on Movement Pattern Quality and Dynamic Postural Control by Christopher Rosenborough, Sean M. Collins, Edward Smith, Thomas G Bowman

“…# Background/Purpose No studies have observed the effects of a collegiate lacrosse season on movement pattern quality, dynamic postural control, or the accuracy of athletes’ perceived movement pattern quality. …”
Get full text

Coverage of continuum of Maternal, Newborn and Child Health (MNCH) care in a nationally representative sample of 40,687 mother–child dyads of India: a report from NFHS-5 by Jyoti Ghosal, Anita Nanda, Pallavi Behera, Meena Som, Madhusmita Bal, Manoranjan Ranjit, Srikanta Kanungo, Shridhar Murlidharrao Kadam, Sanghamitra Pati, Ambarish Dutta

“…Abstract Background A package of Maternal, Newborn and Child Health (MNCH) services are administered sequentially to mother–child dyads as Continuum of Care (CoC), but often each intervention is reviewed in silo in low-middle-income countries like India. …”
Get full text

Reduced Muscle Loss in Patients With NSCLC Taking Fibrates: Findings From a Retrospective Observational Study by Rahmi Elahjji, Tahj Blow, Rahul Grover, Maurice A. Hurd, Richard F. Dunne, Bette J. Caan, Elizabeth M. Cespedes Feliciano, Andrew J. Plodkowski, James H. Flory, Marcus D. Goncalves

“…ABSTRACT Background The cancer‐anorexia‐cachexia syndrome (CACS) is a common and debilitating wasting disorder characterized by loss of skeletal muscle and worse morbidity and mortality. …”
Get full text

Predictive values for different cancers and inflammatory bowel disease of 6 common abdominal symptoms among more than 1.9 million primary care patients in the UK: A cohort study. by Annie Herbert, Meena Rafiq, Tra My Pham, Cristina Renzi, Gary A Abel, Sarah Price, Willie Hamilton, Irene Petersen, Georgios Lyratzopoulos

“…<h4>Background</h4>The diagnostic assessment of abdominal symptoms in primary care presents a challenge. …”
Get full text

Variation of Mg isotopes during mineral dissolution at pH = 1 and T = 25 °C: Part 1. Hornblende and chlorite by Jong-Sik Ryu

“…Abstract Background Silicate mineral weathering, particularly involving Mg-bearing minerals like hornblende and chlorite, plays a crucial role in the global geochemical cycle of magnesium. …”
Get full text