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3061
Immune cell topography of head and neck cancer
Published 2024-07-01“…Background Approximately 50% of head and neck squamous cell carcinomas (HNSCC) recur after treatment with curative intent. …”
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3062
Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation
Published 2024-05-01“…However, it remains unknown whether and how FPHA affects the immune microenvironment of the bone defects. Methods FPHA was synthesized and its composition and structural properties were confirmed. …”
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3063
Improving the Synthesis of Odd-Chain Fatty Acids in the Oleaginous Yeast <i>Yarrowia lipolytica</i>
Published 2024-11-01“…(1) Background: Odd-chain fatty acids (OCFAs) have garnered attention for their potential health benefits and unique roles in various biochemical pathways. …”
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3064
A Novel Metabolic Risk Classification System Incorporating Body Fat, Waist Circumference, and Muscle Strength
Published 2025-02-01“…It aims to improve risk stratification and evaluate the association with metabolic syndrome. <b>Methods</b>: This cross-sectional study involved 300 young adults (18–22 years) from a university in Mexico City, utilizing body composition (%BF) and anthropometric measures (WC, GS) to categorize them into four risk groups: protective, low risk, increased risk, and high risk. …”
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3065
Spatial distribution and determinants of children ever born among reproductive age women in Ethiopia: spatial and multilevel analysis of 2019 mini Ethiopian demographic health surv...
Published 2025-02-01“…BackgroundUnderstanding population dynamics is essential since the number of children ever born (CEB) affects the growth, composition, and structure of a nation's population. …”
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3066
Hepatocyte-derived liver progenitor-like cells attenuate liver cirrhosis via induction of apoptosis in hepatic stellate cells
Published 2025-02-01“…Background:. Cell therapy demonstrates promising potential as a substitute therapeutic approach for liver cirrhosis. …”
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3067
Episode-specific cortical functional connectome reorganization and neurobiological correlates in bipolar disorder: a cross-sectional study
Published 2025-08-01“…Abstract Background Bipolar disorder (BD) is a heterogeneous psychiatric condition characterized by distinct episodes: manic (BipM), depressive (BipD), mixed (mBD), and remission (rBD). …”
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3068
A study on the mechanism of Bushen Kaiqiao Formula in modulating microglial activation to alleviate neuroinflammation in ADHD
Published 2025-09-01“…Utilizing spontaneously hypertensive rats—a well-validated animal model of ADHD—this study aimed to characterize ADHD-like behavioral phenotypes and prefrontal cortical neuronal development and elucidate the neuroimmunological mechanisms through which the Bushen Kaiqiao Formula (BSKQF) exerts its therapeutic effects by modulating microglial activation states. Methods: Ultra-high-performance liquid chromatography coupled with a tandem mass spectrometer (UHPLC-MS/MS) was used to qualitatively analyze the chemical composition of Bushen Kaiqiao Formula, and network pharmacology was applied to predict its potential therapeutic targets and ADHD-related pathways ADHD-like behaviors, including hyperactivity, impulsivity, spatial memory, and attention, were assessed using the Open Field Test, Elevated Plus Maze, and Y-Maze Test at weeks 2 and 4. …”
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3069
Novel potential biomarkers for predicting childhood caries via metagenomic analysis
Published 2025-06-01“…BackgroundDental caries is a prevalent global health issue, particularly among children, with significant oral and overall health implications. …”
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3070
Fermented palm kernel waste with different sugars as substrate for black soldier fly larvae
Published 2024-01-01“…BACKGROUND AND OBJECTIVES: The palm industry generates several waste products. …”
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3071
Dietary Qiwenghuangbo powder–enriched Limosilactobacillus reuteri protects the intestinal epithelium and alleviates inflammation via a strain‐specific mechanism
Published 2025-06-01“…Abstract Background Qiwenghuangbo powder (QP), composed of Astragalus, Phellodendron chinensis, and Radix pulsatilla, is a traditional Chinese herbal formula, but its effects on weaned piglets remained unclear. …”
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3072
Aloe vera-derived extracellular vesicle-like particles suppress pancreatic carcinoma progression through triggering pyroptosis via ROS-GSDMD/E signaling pathway
Published 2025-07-01“…Abstract Background Pancreatic carcinoma (PC) remains one of the most aggressive malignancies that is often referred to as the “king of cancers” in clinic. …”
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3073
Maternal dysglycaemia, changes in the infant's epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial.
Published 2020-11-01“…<h4>Background</h4>Higher maternal plasma glucose (PG) concentrations, even below gestational diabetes mellitus (GDM) thresholds, are associated with adverse offspring outcomes, with DNA methylation proposed as a mediating mechanism. …”
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3074
Effect of mixed protein supplementation on golf performance and muscle function: a randomized, double-blind, placebo-controlled study
Published 2024-12-01“…Background As a relatively novel approach to enhancing skeletal muscle health, mixed protein supplementation has shown similar responses to whey protein. …”
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3075
Varied cellular abnormalities in thin vs. normal endometrium in recurrent implantation failure by single-cell transcriptomics
Published 2024-07-01“…Abstract Background Reduced endometrium thickness and receptivity are two important reasons for recurrent implantation failure (RIF). …”
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3076
Investigation of Bioactive Compounds Extracted from <i>Verbena officinalis</i> and Their Biological Effects in the Extraction by Four Butanol/Ethanol Solvent Combinations
Published 2025-07-01“…<b>Background/Objectives</b>: <i>Verbena officinalis</i> L. …”
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3077
Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacement
Published 2025-07-01“…BackgroundMyeloid cells, such as resident microglia (MG), infiltrating monocytes (Mo), macrophages (MΦ), and CNS border-associated macrophages (BAM) in the brain, participate in aged brain injury. …”
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3078
Fluctuating saline conditions favor competition of Bolboschoenus planiculmis, a dominant species in inland salt marshes
Published 2025-08-01“…Abstract Background The changing hydrological conditions in wetland ecosystems are often accompanied by salt fluctuations. …”
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3079
Fingerprint Profile Analysis of <i>Eupolyphaga steleophaga</i> Polypeptide Based on UHPLC-MS and Its Application
Published 2025-01-01“…<b>Background and Objectives:</b> As a medicinal and food homologous substance, <i>Eupolyphaga steleophaga</i> is renowned for its potential health benefits, including anti-tumor effects, immune system support, and anti-inflammatory properties. …”
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3080
ESTIMATION OF TENDENCIES IN THE HEIGHT OF THE SNOW COVERAT WEATHER STATIONS IN THE NORTHERN CAUCASUS
Published 2022-07-01“…Introduction. Against the background of global warming observed in recent decades, changes in all climatic characteristics are taking place. …”
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