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2941
Coral microbiome in estuary coral community of Pearl River Estuary: insights into variation in coral holobiont adaptability to low-salinity conditions
Published 2025-05-01“…Abstract Background Low salinity is a crucial environmental stressor that affects estuarine coral ecosystems considerably. …”
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2942
Ginsenoside Reshapes Intestinal Microecology to Alleviate Microgravity Stress
Published 2025-02-01“…This study focused on the regulation of GTSs in intestinal homeostasis imbalance caused by microgravity.Methods: A hindlimb suspension (HLS) rat model was established to evaluate the intestinal protective effects of GTSs. …”
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2943
Integrated in-silico design and in vivo validation of multi-epitope vaccines for norovirus
Published 2025-05-01“…Abstract Background Norovirus (NoVs) is a foodborne pathogen that causes acute gastroenteritis. …”
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2944
Inulin Diet Alleviates Abdominal Aortic Aneurysm by Increasing Akkermansia and Improving Intestinal Barrier
Published 2025-04-01“…<b>Background/Objectives</b>: Previous studies have shown varying efficacy of high-fiber diets containing different ingredients in abdominal aortic aneurysms (AAAs). …”
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2945
Nutritional deficiency in patients with newly diagnosed diffuse large B-cell lymphoma Prevalence and approaches to correction
Published 2024-09-01“…To assess the prevalence of nutritional deficiency, features of usual diet energy and protein composition in patients with diffuse large B-cell lymphoma who are starting antitumor treatment.Materials and methods. …”
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2946
Effects of saffron-grape intercropping on saffron flower number and rhizosphere microbial community
Published 2024-12-01“…In our study, we counted the number of saffron flowers in two cropping patterns (saffron monoculture and saffron-grape intercropping), and analyzed the microbial community diversity and composition using Illumina high-throughput sequencing methods based on 16 S and ITS amplicons. …”
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2947
Curcumin supplementation accelerates high-altitude acclimatization, prevents polycythemia and modulates gut microbiota in male Han population: a randomized controlled trial
Published 2025-07-01“…BackgroundPrevious evidence showed that curcumin enhanced the oxygen supply efficiency of hemoglobin and alleviated acute plateau hypoxia injury in animal models. …”
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2948
Microhardness, Structure, and Morphology of Primary Enamel after Phosphoric Acid, Self-Etching Adhesive, and Er:YAG Laser Etching
Published 2017-01-01“…Background. Phosphoric acid is the traditional etching agent; self-etching adhesives and Er:YAG laser are alternative methods. …”
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2949
The evolution of sprinting performance: Technological and regulatory influences from 1976 to 2024
Published 2025-06-01“…Background: This study examines the progression of sprinting performance across the 100m, 200m, and 400m events from 1976 to 2024, highlighting the influence of technological advancements and regulatory changes. …”
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2950
Anti-Infection Efficacy, Osteogenesis Potential, and Biocompatibility of 3D Printed PLGA/Nano-Hydroxyapatite Porous Scaffolds Grafted with Vancomycin/DOPA/rhBMP-2 in Infected Rabbi...
Published 2025-05-01“…Through the three-dimensional (3D) printing technology, we fabricated a poly(lactic-co-glycolic acid)(PLGA)/nano-hydroxyapatite (n-HA) composite scaffold grafted with the antibiotic vancomycin and loaded with the osteoinductive agent recombinant human bone morphogenic protein-2 (rhBMP-2) via polydopamine (DOPA) chemistry, whose therapeutic effects on IBD were determined.Methods: After examining the hydrophilicity, surface chemical composition, mechanical properties, and drug release of the PLGA/n-HA, PLGA/n-HA/VAN, and PLGA/n-HA/VAN+DOPA/rhBMP-2 composite scaffolds, pre-osteoblast MC3T3-E1 cells were seeded onto the scaffold surface to assess the biocompatibility and osteoconductive properties of the scaffolds in vitro. …”
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2951
The role and mechanism of CHMP4C in poor prognosis and drug sensitivity of lung adenocarcinoma
Published 2025-03-01“…Abstract Background Chromatin modified protein 4C (CHMP4C) is a charged polyvesicular protein (CHMP) that is involved in the composition of the endosomal sorting complex (ESCRT-III) required for transport III and promotes the necessary separation of daughter cells. …”
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2952
Interval Hypoxic Training in Rehabilitation Program for Adolescents with Overweight / Obesity and Comorbid Arterial Hypertension: Open-Label Randomized Study
Published 2021-03-01“…Background. Searching for new strategies for the rehabilitation of adolescents with obesity and comorbid arterial hypertension (AHT) before significant pathological changes development in the cardiovascular system remains the urgent challenge. …”
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2953
Characterization of tumor-infiltrating lymphocytes and their spatial distribution in triple-negative breast cancer
Published 2024-12-01“…Abstract Background The tumor immune microenvironment, particularly tumor-infiltrating lymphocytes (TILs), plays a critical role in disease progression and treatment response in triple-negative breast cancers (TNBCs). …”
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2954
Fatty pancreas disease in newly diagnosed type 2 diabetes patients: a case–control study on relationships with glycemic control and exocrine function
Published 2025-03-01“…Abstract Background Fatty pancreas disease (FPD) is characterized by abnormal fat accumulation in pancreatic tissue and is often associated with obesity, metabolic syndrome, and type 2 diabetes mellitus (T2DM). …”
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2955
Tracking Coronavirus 2019 pandemic-related waste generation in urban waterways
Published 2025-07-01“…BACKGROUND AND OBJECTIVES: The Coronavirus 2019 pandemic has revealed significant shortcomings in the Philippines’ solid waste management system, particularly in addressing the surge of pandemic-related waste. …”
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2956
Hypertension and Elevated Pulse Pressure Responsive to Biomass Pollutants Exposures in Young Workers From the Democratic Republic of Congo: A Cross‐Sectional Analysis
Published 2025-05-01“…Background Occupational biomass pollutant exposure as observed in charcoal workers may have significant cardiovascular effects. …”
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2957
PD-L1 deficiency exacerbates colitis severity by remodeling gut microbiota in inflammatory bowel disease
Published 2025-06-01“…As an essential immune checkpoint, Programmed death-ligand 1 (PD-L1) has been implicated in modulating gut microbiota composition. However, the precise role of PD-L1 in shaping metagenomic profiles during IBD-associated colitis remains unexplored.MethodsDSS-induced colitis was established in both PD-L1 knockout (Pdcd1lg1-/-) mice and wild-type (wt) control mice. …”
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2958
Integration of stool microbiota, proteome and amino acid profiles to discriminate patients with adenomas and colorectal cancer
Published 2022-12-01“…Background Screening for colorectal cancer (CRC) reduces its mortality but has limited sensitivity and specificity. …”
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2959
Combined microbial inoculation and reduced inorganic fertilization enhances diversity and functionality in potato rhizosphere microbiome at field scale
Published 2025-08-01“…Abstract Background Intensive potato farming heavily relies on mineral fertilizers which can be detrimental to the environment. …”
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2960
Progression to fibrosis and hepatocellular carcinoma in DEN CCl4 liver mice, is associated with macrophage and striking regulatory T cells infiltration
Published 2025-07-01“…This study investigates immune dysregulation that occurs during the progression of CLD to HCC by delineating changes in immune cell composition and distribution within the liver microenvironment.MethodsMice were injected with Diethylnitrosamine (DEN) at 4 weeks of age, followed by continuous tri-weekly injections of carbon tetrachloride (CCl4) for 6 and 21 weeks to induce liver fibrosis and HCC. …”
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