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2901
A COMPREHENSIVE REVIEW OF THE SELF-EMULSIFYING DRUG DELIVERY SYSTEM (SEDDS) AND ITS RECENTLY DEVELOPED FORMULATIONS
Published 2024-03-01“… Background: Poor water solubility of the therapeutic compounds has become a very challenging issue for the delivery of drugs through conventional approaches. …”
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2902
Bifidobacterium longum subsp. longum dipro-O: a potential therapeutic agent for ameliorating metabolic disorders in high-fat diet-induced obesity mouse model
Published 2025-06-01“…BackgroundExcessive fat intake results in lipid metabolic disorders accompanied by inflammation and other complications. …”
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2903
Structural Characterizations and Biological Evaluation of a Natural Polysaccharide from Branches of <i>Camellia oleifera</i> Abel
Published 2025-01-01“…Background: <i>Camellia oleifera</i> Abel (<i>C. oleifera</i>) is widely cultivated and serves as an important source of edible oil. …”
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2904
Sensitivity of microflora of mammary gland secretion to antibiotics in mastitis in cats
Published 2024-12-01“…As a result, there is a real danger of the emergence of a common microbial background in which an exchange of bacterial pathogens with emerging resistance to antibiotics can occur. …”
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2905
Single-cell transcriptomics in colorectal cancer uncover the potential of metastasis and immune dysregulation of a cell cluster overexpressed PRSS22
Published 2025-05-01“…With the rapid development of single-cell sequencing technology, we can now delve deeper into the cellular composition and dynamic changes within the tumor microenvironment, revealing cellular interactions and their potential roles in tumorigenesis.MethodIn this study, we systematically analyzed comprehensive single-cell RNA sequencing data from 25 colorectal cancer and 10 adjacent normal tissue samples. …”
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2906
Cervical-vaginal dysbiosis: Clinical query of infections in selected private medical laboratories in Abakaliki Ebonyi State Nigeria
Published 2023-09-01“…Cervical-Vaginal Dysbiosis refers to an imbalance or disruption in the microbial communities inhabiting the cervix and vaginal tract, leading to an altered composition of microorganisms, often accompanied by a decline in overall vaginal health. …”
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2907
Association between appendicular skeletal muscle mass and myocardial glucose uptake measured by 18F‐FDG PET
Published 2025-02-01“…Abstract Background Low muscle mass is associated with high insulin resistance and an increased risk of cardiovascular disease. …”
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2908
Phytochemistry and pharmacological potential of aloscasia macrorrhiza: A comprehensive review
Published 2024-12-01“…Background: Aloscasia macrorrhiza, commonly known as Giant Taro, is a species rich in phytochemicals with diverse pharmacological properties. …”
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2909
Measuring shoulder range of motion to diagnose shoulder injury among weightlifters: a study in athletes with and without shoulder injury
Published 2024-10-01“… Background: Weightlifting is one of the sports that contribute to Olympic medals for Indonesia. …”
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2910
The effect of amycretin, a unimolecular glucagon-like peptide-1 and amylin receptor agonist, on body weight and metabolic dysfunction in mice and ratsResearch in context
Published 2025-08-01“…Summary: Background: Amycretin is a novel unimolecular glucagon-like peptide-1 (GLP-1) and amylin receptor agonist. …”
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2911
Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation
Published 2025-07-01“…This study aimed to examine the molecular mechanisms underlying the involvement of NSUN2 in immune evasion and metabolic reprogramming of HCC. Methods Single‐cell transcriptomic sequencing was applied to examine cellular composition changes, particularly immune cell dynamics, in HCC and adjacent normal tissues. …”
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2912
Gender and cultural aspects of brucellosis transmission and management in Nakasongola cattle corridor in Uganda.
Published 2025-01-01“…<h4>Background</h4>Brucellosis is a zoonotic disease with significant public health and economic effects on societies. …”
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2913
Optical Characterization of Fluorescent Chitosan-Based Carbon Dots Embedded in Aqueous Natural Dye
Published 2024-10-01“…(1) Background: This work evaluated the optical characterization of aqueous fluorescent chitosan-based carbon dots (or carbon nanoparticles CNPs) embedded in natural dye for potential functional packaging applications. …”
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2914
Mitochondrial Dysfunction Contributes to Sustained Muscle Loss After Cardiac Surgery: A Prospective Observational Study
Published 2025-08-01“…ABSTRACT Background As a major systemic insult, cardiac surgery can lead to significant muscle loss, which increases the time to recovery as well as being correlated with mortality. …”
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2915
Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction
Published 2019-05-01“…As co-stimulation via T cell-mediated CD40L is essential for driving inflammation, we here investigate the role of T cell CD40L in DIO.Research design and methods CD4CreCD40Lfl/fl mice on a C57BL/6 background were generated and subjected to DIO by administration of 15 weeks of high fat diet (HFD).Results HFD-fed CD4CreCD40Lfl/fl mice had similar weight gain, adipocyte sizes, plasma cholesterol and triglyceride levels as their wild-type (WT) counterparts. …”
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2916
Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3+ and CD8+ T cell density and predict prognosis in hepatocellular carcinoma
Published 2022-03-01“…Background Hepatocellular carcinoma (HCC) is a highly lethal cancer and the second leading cause of cancer-related deaths worldwide. …”
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2917
Abundance of Gut Microbiota, Concentration of Short-Chain Fatty Acids, and Inflammatory Markers Associated with Elevated Body Fat, Overweight, and Obesity in Female Adolescents
Published 2019-01-01“…Background and Aims. Overweight is ever more prevalent in the pediatric population, and this cardiometabolic factor can be associated with inflammatory markers, gut microbiota composition, and short-chain fatty acid (SCFA) concentrations. …”
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2918
Green synthesis of titanium dioxide photocatalyst using Lactobacillus bulgaricus for processing palm oil mill effluent
Published 2024-01-01“…The effectiveness of titanium dioxide as a photocatalyst depends on the synthesis method used. The method affect the particle size, crystallinity and phase composition of the produced catalyst. …”
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2919
The Positive Regulatory Effect of DBT on Lipid Metabolism in Postpartum Dairy Cows
Published 2025-01-01“…Background/Objectives: The transition from a non-lactating to a lactating state is a critical period for lipid metabolism in dairy cows. …”
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2920
Exploring the active chemical compounds and pharmacological effects of Artemisia Argyi leaves through commonality, authenticity and aging
Published 2025-11-01“…Background: Artemisia argyi (A. argyi), a pivotal herb extensively used in moxibustion therapy, has long been widely recognized in Traditional Chinese Medicine (TCM) for its significant clinical efficacy. …”
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