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  1. 2781

    Exploring the bacterial communities in date palm roots in saline versus non-saline environment by Shafeeq Rahman, Manzoor Ahmad, Mughair Abdul Aziz, Taif Ibrahim Alrayssi, Asma Saleh Mohammad, Reem Alothman, Khaled Masmoudi

    Published 2025-07-01
    “…Abstract Background Bacterial communities associated with plant roots significantly influence plant growth and adaptation to environmental stresses, particularly in arid agroecosystems. …”
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    Article
  2. 2782

    Osteogenic and Antibacterial Response of Levofloxacin-Loaded Mesoporous Nanoparticles Functionalized with <i>N</i>-Acetylcysteine by Alberto Polo-Montalvo, Natividad Gómez-Cerezo, Mónica Cicuéndez, Blanca González, Isabel Izquierdo-Barba, Daniel Arcos

    Published 2025-04-01
    “…These nanoparticles would present antibacterial activity able to disintegrate the biofilm and regenerate the peri-implantar osseous tissue. <b>Methods</b>: MBGN of composition 82.5 SiO<sub>2</sub>—17.5 CaO have been synthesized, loaded with levofloxacin, and functionalized with NAC (MBGN-L-NAC). …”
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    Article
  3. 2783

    Preliminary Evaluation of 3D-Printed Alginate/Gelatin Scaffolds for Protein Fast Release as Suitable Devices for Personalized Medicine by Benedetta Ghezzi, Ruben Foresti, Luisa Pia Scialoia, Maddalena Botti, Arianna Mersanne, Fulvio Ratto, Francesca Rossi, Chiara Martini, Paolo Perini, Elda Favari, Antonio Freyrie

    Published 2025-06-01
    “…<b>Background/Objectives:</b> Drug-coated balloons (DCBs) are emerging as a promising treatment for peripheral artery disease; however, current technologies lack flexibility in customizing drug release profiles and composition, limiting their therapeutic potential. …”
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    Article
  4. 2784

    Global burden of gallbladder and biliary diseases (1990–2021) with healthcare workforce analysis and projections to 2035 by Fangyi Dai, Yuzhou Cai, Shangjin Yang, Jingyang Zhang, Yong Dai

    Published 2025-04-01
    “…Abstract Background Gallbladder and biliary tract diseases pose a significant global health burden, yet comprehensive analyses of their long-term epidemiological trends and future projections remain limited. …”
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  5. 2785
  6. 2786

    Evaluation of the Cytotoxicity, Genotoxicity and Acute Oral Toxicity of <i>Thymus longicaulis</i> subsp. <i>chaubardii</i> (Rchb.f.) Jalas by Ayfer Beceren, Ayse Nur Hazar-Yavuz, Ozlem Bingol Ozakpinar, Duygu Taskin, Ismail Senkardes, Turgut Taskin, Ozlem Tugçe Cilingir-Kaya, Ahmad Kado, Elif Caliskan Salihi, Hatice Kubra Elcioglu

    Published 2025-07-01
    “…The aim of this study was to determine its phytochemical profile and to evaluate its cytotoxic, genotoxic and acute oral toxicity effects. <b>Methods</b>: The phenolic composition of the methanolic extract was determined by HPLC-DAD. …”
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    Article
  7. 2787

    Depression as a risk factor for osteoporosis independent of sarcopenia in hemodialysis patients: findings from a multicenter cross-sectional study by Xiaohua Hu, Xianwu Ye, Haimin Chen, Bibo Wu, Qi Guo, Chen Yu, Wei Ding, Jianying Niu, Junli Zhao, Hualin Qi, Suhua Zhang, Cheng Xue, Liming Zhang

    Published 2025-01-01
    “…Abstract Background Osteoporosis and sarcopenia frequently occur in patients with end-stage renal disease undergoing hemodialysis (HD), and depression is also a common mental health issue in this population. …”
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    Article
  8. 2788

    PM2.5 exposure reprograms cell cycle dynamics in uterine immune cells at single-cell resolution by Lin Zhang, Lin Zhang, Lin Zhang, Jiaqi Tian, Jiaqi Tian, Jiaqi Tian, Yongfei Zheng, Shuyin Duan

    Published 2025-04-01
    “…BackgroundFine particulate matter (PM2.5) exposure has been associated with adverse effects on reproduction, yet the underlying cellular mechanisms remain poorly understood.MethodsUsing single-cell RNA sequencing, we systematically investigated cell cycle dynamics of immune cell populations in the mouse uterus following PM2.5 exposure. …”
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    Article
  9. 2789

    Changes in Cytokines and Fibrotic Growth Factors after Low-Carbohydrate or Low-Fat Low-Energy Diets in Females with Lipedema by Julianne Lundanes, Vilde Fiske Nes, Oda Aakervik, Liv Ryan, Patrik Hansson, Anne Mari Rokstad, Catia Martins, Siren Nymo

    Published 2025-03-01
    “…Background: Lipedema is considered an inflammation-related disease, and low-carbohydrate ketogenic diets may help reduce inflammation. …”
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    Article
  10. 2790

    Chemical Changes Associated with Increased Acid Resistance of Er:YAG Laser Irradiated Enamel by Jennifer Manuela Díaz-Monroy, Rosalía Contreras-Bulnes, Oscar Fernando Olea-Mejía, María Magdalena García-Fabila, Laura Emma Rodríguez-Vilchis, Ignacio Sánchez-Flores, Claudia Centeno-Pedraza

    Published 2014-01-01
    “…Background. An increase in the acid resistance of dental enamel, as well as morphological and structural changes produced by Er:YAG laser irradiation, has been reported. …”
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    Article
  11. 2791

    Characterizing the microstructural transition at the gray matter-white matter interface: Implementation and demonstration of age-associated differences by Joan Y Song, Roman Fleysher, Kenny Ye, Mimi Kim, Molly E Zimmerman, Richard B Lipton, Michael L Lipton

    Published 2025-02-01
    “…Background: The cortical gray matter-white matter interface (GWI) is a natural transition zone where the composition of brain tissue abruptly changes and is a location for pathologic change in brain disorders. …”
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    Article
  12. 2792

    Gut microbiota dysbiosis in patients with Alzheimer’s disease and correlation with multiple cognitive domains by Qionglei Chen, Jiayu Shi, Gaojie Yu, Huijia Xie, Shicheng Yu, Jin Xu, Jiaming Liu, Jing Sun

    Published 2024-11-01
    “…The aim of this study was to explore microbial signatures associated with global cognition and specific cognitive domains in AD patients and to determine their predictive value as biomarkers.MethodsA total of 64 subjects (18 mild AD, 23 severe AD and 23 healthy control) were recruited in the study. 16 s rDNA sequencing was performed for the gut bacteria composition, followed by liquid chromatography electrospray ionization tandem mass spectrometry (LC/MS/MS) analysis of short-chain fatty acids (SCFAs). …”
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    Article
  13. 2793

    Association analysis-based screening strategy for quality markers of Tengdan capsule in the treatment of hypertensive renal disease by Jing Liu, Jun Li, Wei Zhang, Yu Dong, Fang Wang, Jinzhe Liu, Yong Wang, Qian Zhang, Xiaoli Du

    Published 2025-08-01
    “…This study aimed to identify candidate Q-markers of TDC and elucidate the molecular pathways through which it exerts its renoprotective effects, using an integrative association analysis-based approach.MethodsThe chemical composition of TDC and its potential Q-markers were systematically characterized through in vitro and in vivo profiling using HPLC-Q-Exactive-MS and chromatographic fingerprinting. …”
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    Article
  14. 2794

    Circ_HUWE1: a novel regulator of lipid accumulation, inflammation, and gut microbiota in atherosclerosis by Zulong Sheng, Yi Fan, Zhenjun Ji, Yanru He, Rui Zhang, Yuyu Yao, Genshan Ma

    Published 2025-07-01
    “…Abstract Background Atherosclerosis (AS) is a chronic cardiovascular disease characterized by lipid accumulation and inflammation within arterial walls, leading to plaque formation and cardiovascular events. …”
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    Article
  15. 2795

    <i>Cystoseira spinosa</i> Polysaccharide: A Promising Natural Source for Antioxidant, Pro-Angiogenic, and Wound Healing Applications: In Silico Study by Mouhamed Ayad Berfad, Intissar Kammoun, Marwa Lakhrem, Zakaria Boujhoud, Malek Eleroui, Manel Mellouli, Saadia Makni, Majed Kammoun, Riadh Badraoui, Jean Marc Pujo, Hatem Kallel, Ibtissem Ben Amara

    Published 2025-05-01
    “…Collected off the coast of Alkhoms, Libya, PCS was investigated for its wound-healing and pro-angiogenic properties, addressing the need for natural bioactive compounds in therapeutic applications. <b>Methods:</b> The monosaccharide composition of PCS was analyzed using HPLC-RID, identifying glucuronic acid and xylose as major components. …”
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    Article
  16. 2796
  17. 2797

    CXCL12/CXCR4 axis governs Treg spatial dominance over CD8+ T cells via IL-2 sequestration: a dual therapeutic target in prostate cancer by Junyi Li, Long Zhang, Ruoyang Liu, Changwen Xu, HuiHui Tang, Yunfei Zou, Qingfei Cao, Weichao Huang

    Published 2025-07-01
    “…BackgroundProstate cancer (PCa) is characterized by high incidence and recurrence rates, presenting as an immune ‘cold’ tumor that exhibits a poor response to immunotherapy. …”
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    Article
  18. 2798

    Muscle Mass Index Decline as a Predictor of Lung Function Reduction in the General Population by Joon Young Choi, Chin Kook Rhee, Sang Hyuk Kim, Yong Suk Jo

    Published 2025-02-01
    “…We aimed to clarify this dynamic relationship by examining how changes in muscle mass impact pulmonary function and the development of respiratory symptoms. Methods We utilized the Ansan and Ansung Cohort Study of the Korean Genome and Epidemiology Study (KoGES) database, a large‐scale prospective cohort, enrolling participants aged 40 to 69 years with lung function and body composition measurements. …”
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    Article
  19. 2799

    Hirsutella sinensis polysaccharides and Parabacteroides goldsteinii reduce lupus severity in imiquimod-treated mice by Shih-Hsin Chang, Yun-Fei Ko, Jian-Ching Liau, Cheng-Yeu Wu, Tsong-Long Hwang, David M. Ojcius, John D. Young, Jan Martel

    Published 2025-04-01
    “…Background: The incidence of autoimmune diseases is increasing in developed countries, possibly due to the modern Western diet and lifestyle. …”
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    Article
  20. 2800