Metagenome association study of the gut microbiome revealed biomarkers linked to chemotherapy outcomes in locally advanced and advanced lung cancer by Zhe Zhao, Kailun Fei, Hua Bai, Zhijie Wang, Jianchun Duan, Jie Wang

“…Background The gut microbiome is important in the development and immunotherapy efficacy of lung cancer. …”
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Engineered <i>Escherichia coli</i> Nissle 1917 Expressing IGF1 and FGF19 Reduce Liver Fat Accumulation and Restore Microbial Equilibrium in a Metabolic Dysfunction-Associated Steat... by Johnson Lok, Valeria Iannone, Carlos Gómez-Gallego, Ruben Vazquez-Uribe, Morten Otto Alexander Sommer, Marjukka Kolehmainen, Hani El-Nezami

“…Background and objectives: Endocrine dysregulation and intestinal microbiota unbalance are commonly associated with metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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Potential activity of Ferula macrecolea essential oil for treating Giardia lamblia infection through modulating electrolytes and suppressing NF-κB p65 pathway by Iraj Salimikia, Seyed Ehsan Yaghoubi, Amal Khudair Khalaf, Leila Masoori, Javad Ghasemian Yadegari, Hossein Mahmoudvand, Hossein Mahmoudvand

“…In light of the previously discussed information and the recognized antimicrobial properties of Ferula macrecolea, this study aims to investigate both the in vitro and in vivo anti-giardial effects of F. macrecolea essential oil (FME) on G. lamblia infection.MethodsGas chromatography-mass spectrometry (GC-MS) was utilized to analyze the chemical composition of the prepared FME. …”
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Single-cell transcriptomics reveal the prognostic roles of epithelial and T cells and DNA methylation-based prognostic models in pancreatic cancer by Jing Du, Yaqian Zhao, Jie Dong, Peng Li, Yan Hu, Hailang Fan, Feifan Zhang, Lanlan Sun, Dake Zhang, Yuhua Zhang

“…Abstract Background Pancreatic adenocarcinoma (PDAC) exhibits a complex microenvironment with diverse cell populations influencing patient prognosis. …”
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Characterization of the enteric virome of clinically healthy pigs around weaning on commercial farms in the Netherlands using next generation sequencing and qPCR by M.A.R. Schyns, R. van den Braak, J. Peijnenborg, S. Coppens, M. Deijs, M. G.J.M. Burggraaff, W. I. Kuller, S. Theuns, L. van der Hoek, A. de Groof

“…Abstract Background Enteric virus infections around time of weaning have always been related to pig diseases such as postweaning diarrhea. …”
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Risk factors for decreased bone mineral density in men with type 2 diabetes. by Olga N. Fazullina, Anton I. Korbut, Maksim V. Dashkin, Vadim V. Klimontov

“…BACKGROUND: Type 2 diabetes and osteoporosis are widespread diseases in the middle-aged and elderly people. …”
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Spatial transcriptomic analysis of tumor microenvironment in esophageal squamous cell carcinoma with HIV infection by Yuanli Zuo, Yang Jin, Gang Li, Yue Ming, Ting Fan, Yitong Pan, Xiaojun Yao, Yong Peng

“…Abstract Background Human Immunodeficiency Virus (HIV) is one of the most prevalent viruses, causing significant immune depletion in affected individuals. …”
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Use of Low-Protein Enriched Starch Products in Diet Therapy of Children With Phenylketonuria Aged Over One Year by Tatiana V. Bushueva, Tatiana E. Borovik, Natalya N. Semyonova, Vera A. Skvortsova, Natalia G. Zvonkova, Irina M. Guseva, Elena A. Roslavtseva, Tatyana N. Stepanova, Olga L. Lukoyanova, Anait K. Gevorkyan, Svetlana Т. Bykova, Tamara G. Kalinina

“…Background. The nutrition of children with phenylketonuria includes specialized starch-based products, the range of which is constantly expanding. …”
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Immunogenic Activity of Secreted Protein-Based Compounds Staphylococcus aureus № 6 by I. M. Gruber, E. A. Astashkina, O. V. Lebedinskaya, N. B. Egorova, M. V. Kiselevsky, F. V. Donenko, N. E. Yastrebova, O. M. Ignatova, E. A. Kurbatova, L. S. Cherkasova

“…Difficulties in the therapy of infection, caused by S. aureus, depends on the resistance of staphylococci to antibiotics, proceeding to chronicity of the diseases and the development on that background the depression of innate immunity functions and decreasing of the host resistance to the infection. …”
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Medical Hemorrhoid Gel Ameliorates Croton Oil-Induced Hemorrhoids by Suppressing the NLRP3 Inflammasome Activation via NF-&amp;kappa;B Signaling Pathway by Ai Z, Yuan D, Li Y, Cai J, Zhou D, Liu W

“…This study aims to systematically evaluate the safety, efficacy, and mechanism of action of MHG in treating HD.Methods: The phytochemical composition of MHG was characterized using UPLC-QTOF-MS/MS and GC-MS/MS analyses. …”
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Modulation of the Plasma Lipidomic Profile in Piglets Fed Polar Lipid-Rich Diets by Rayllana Larsen, Salma Chakroun, Marie-Pierre Létourneau-Montminy, Janie Levesque, Dimas Estrasulas de Oliveira, Jorge Eduardo Rico, Daniel E. Rico

“…<b>Background:</b> Polar lipids from dairy are novel sources of energy that may replace other dietary lipids and impact plasma lipidomic profiles in piglets. …”
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Longitudinal Changes in Peripheral and Alveolar Monocyte and Inflammatory Biomarkers are Distinct in Hypercapnia Patients Following Pulmonary Sepsis-Induced ARDS by Zhao J, Ji Y, Li B, Yang K, Sun Q, Ma T, Xie K

“…Our study was designed to compare initial values and longitudinal changes in cellular composition and inflammatory biomarkers between pneumonia sepsis-induced ARDS patients without hypercapnia and hypercapnia patients.Methods: Between Dec 2022-Apr 2023, we prospectively studied 61 severe pneumonia patients. …”
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Rescue of protein dyshomeostasis in hippocampal astrocytes from an Alzheimer’s disease mouse model by stabilizing ER-mitochondrial interactions at a 20 nm distance by Giulia Dematteis, Chunmei Gong, Justyna Malecka, Elisa Tonelli, Armando Genazzani, Laura Tapella, Anna Maria Eleuteri, Dmitry Lim, Laura Bonfili

“…Abstract Background Alzheimer’s disease (AD) is the major age-related form of dementia in which dysfunctional ubiquitin-proteasome system (UPS) and autophagy represent primary mechanisms leading to accumulation of misfolded proteins, dysfunction of astroglial cells, neuroinflammation and neurodegeneration. …”
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Antimicrobial Effectiveness of <i>Ribes nigrum</i> L. Leaf Extracts Prepared in Natural Deep Eutectic Solvents (NaDESs) by Maria-Beatrice Solcan, Ana-Maria Vlase, Gabriel Marc, Dana Muntean, Tibor Casian, George Cosmin Nadăș, Cristiana Ștefania Novac, Daniela-Saveta Popa, Laurian Vlase

“…Background: Blackcurrant (<i>Ribes nigrum</i> L.) leaves are valuable sources of bioactive compounds, including phenolic acids, flavonoids, and tannins, which contribute to their potent antioxidant, anti-inflammatory, and antimicrobial properties. …”
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Elastic Band Training Versus Multicomponent Training and Group-Based Dance on Morphological Variables and Physical Performance in Older Women: A Randomized Controlled Trial by Jordan Hernandez-Martinez, Eduardo Guzmán-Muñoz, Izham Cid-Calfucura, Francisca Villalobos-Fuentes, Daissy Diaz-Saldaña, Ignacia Alvarez-Martinez, María Castillo-Cerda, Tomás Herrera-Valenzuela, Braulio Henrique Magnani Branco, Pablo Valdés-Badilla

“…Background: This study aimed to analyze the effects of elastic band training (EBT) versus multicomponent training (MCT) and group-based dance (GBD) on waist circumference, body composition (body fat percentage and fat-free mass), and physical performance (handgrip strength, HGS; 30-s chair stand; timed up-and-go, TUG) in Chilean older women. …”
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The Structure of Acute Exotoxicosis During the First Three Months of the COVID-19 Pandemic (According to the Acute Toxicosis Department of N.V. Sklifosovsky Research Institute for... by M. V. Belova, K. K. Ilyashenko, A. Yu. Simonova, M. M. Potskhveriya, G. V. Trusov

“…BACKGROUND The self-isolation regime introduced to limit the spread of COVID-19 disrupted the habitual way of life of the majority of the population, which could cause increased anxiety and depressive states in some citizens and lead to the development of acute exotoxicosis.AIM OF STUDY To identify the impact of the COVID-19 pandemic on the structure of acute poisonings based on their comparative analysis for March-May in 2019 and 2020.MATERIAl AND METHODS “Hospital patient cards” of patients who were treated in the Department of Acute Toxicosis and Somatopsychiatric  Disorders of the N. …”
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ECM remodeling by PDGFRβ+ dental pulp stem cells drives angiogenesis and pulp regeneration via integrin signaling by Tiankai Di, Lulu Wang, Chao Feng, Jinlong Xu, Bo Shao, Baixiang Cheng, Liying Wang, Xiao Zhang, Ling Zhang, Yujiang Chen

“…Abstract Background This study investigates the role of PDGFRβ+ dental pulp stem cells (DPSCs) in dental pulp vascular development by remodeling the extracellular matrix (ECM), with implications for angiogenesis and pulp regeneration using GelMA hydrogels. …”
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Recovery of Perennial Plant Communities in Disturbed Hyper-Arid Environments (Sharaan Nature Reserve, Saudi Arabia) by Sami Youssef, Mohamed Djamel Miara, Stéphane Boivin, Robin Sallio, Jérôme Nespoulous, Hassan Boukcim, Sami D. Almalki, Shauna K. Rees, Benjamin P. Y.-H. Lee, Ahmed H. Mohamed

“…Background: Human activities such as agriculture are known to markedly affect natural ecosystems, including plant communities and soil properties. …”
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Malaria epidemics and its drivers in Uganda in 2022 by Maru W. Aregawi, Catherine Maiteki, John C. Rek, Bosco Agaba, Charles Katureebe, Mansour Ranjbar, Chunzhe Zhang, Samson Kiware, Jimmy Opigo

“…Abstract Background In Uganda, malaria is a year-round health threat, with transmission intensity varying across regions. …”
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Association of breast milk microbiota and metabolites with neonatal jaundice by TianYu Liu, TianYu Liu, Yanhan Yuan, Jinying Wei, Jinying Wei, Jiayi Chen, Feng Zhang, Feng Zhang, Juanjuan Chen, Jinping Zhang

“…BackgroundBreast milk is the primary source of nutrition during early life, and existing research indicates that the development of jaundice in breastfed newborns may be linked to specific nutrients or bioactive substances present in breast milk. …”
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