-
2601
Investigation of bacterial microbiota variability in two allopatric populations of Nyssomyia umbratilis, susceptible and nonsusceptible to Leishmania (Viannia) guyanensis infection...
Published 2025-08-01“…Abstract Background Sand flies of the species Nyssomyia umbratilis (Diptera: Psychodidae: Phlebotominae) are vectors of the parasite Leishmania (Viannia) guyanensis, one of the etiological agents of cutaneous leishmaniasis in the Amazon region. …”
Get full text
Article -
2602
Impacts of Protease Sources on Growth and Carcass Response, Gut Health, Nutrient Digestibility, and Cecal Microbiota Profiles in Broilers Fed Poultry-by-Product-Meal-Based Diets
Published 2025-07-01“…Background: The current study aimed to evaluate the effects of the supplementation of protease sources on growth and carcass response, gut health, nutrient digestibility, and cecal microbiota profiles in broilers fed poultry-by-product-meal (PBM)-containing diets. …”
Get full text
Article -
2603
Bioinformatics meets machine learning: identifying circulating biomarkers for vitiligo across blood and tissues
Published 2025-05-01“…BackgroundVitiligo is a skin disorder characterized by the progressive loss of pigmentation in the skin and mucous membranes. …”
Get full text
Article -
2604
Non-Invasive Multiclass Diabetes Classification Using Breath Biomarkers and Machine Learning with Explainable AI
Published 2025-06-01“…This study presents a breath-based multiclass diabetes classification system leveraging only three gas sensors (CO, alcohol, and acetone) to analyze exhaled breath composition. <b>Methods</b>: Breath samples were collected from 58 participants (22 healthy, 7 prediabetic, and 29 diabetic), with blood glucose levels serving as the reference metric. …”
Get full text
Article -
2605
High-intensity resistance and impact training for patients with hormone-sensitive prostate cancer and bone metastases—study protocol of a randomized clinical trial
Published 2025-07-01“…Abstract Background Men with metastatic prostate cancer are at an increased risk of metabolic syndrome, cardiovascular disease, and pathological fracture. …”
Get full text
Article -
2606
Sex-specific differences in preclinical models of advanced chronic liver disease and portal hypertension
Published 2025-06-01“…Abstract Background Chronic liver disease is a major health concern, but sex-specific differences in its pathophysiology remain unclear. …”
Get full text
Article -
2607
The effect of the ketogenic diet on resistance training load management: a repeated-measures clinical trial in trained participants
Published 2024-12-01“…Background The effect of low-carbohydrate high-fat dietary manipulation, such as the ketogenic diet (KD), on muscle strength assessment in resistance-training (RT) participants has focused on the one-repetition maximum test (1-RM). …”
Get full text
Article -
2608
Biostimulant-Based Molecular Priming Improves Crop Quality and Enhances Yield of Raspberry and Strawberry Fruits
Published 2024-11-01“…Background/Objectives: The biostimulant SuperFifty, produced from the brown algae <i>Ascophyllum nodosum</i>, can improve crop quality and yield and mitigate stress tolerance in model and crop plants such as <i>Arabidopsis thaliana</i>, pepper, and tomato. …”
Get full text
Article -
2609
Effects of dietary faba bean (Vicia faba L.) inclusion on carcass characteristics, meat quality, and blood biochemistry in Awassi lambs
Published 2025-07-01“…Background and Aim: The search for sustainable and cost-effective protein alternatives to soybean meal in livestock diets has led to the exploration of legumes such as faba beans [FBs] (Vicia faba L.). …”
Get full text
Article -
2610
Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients
Published 2025-07-01“…Accurate preoperative prediction of the risk of developing hepatic encephalopathy is critical for optimizing the rational clinical application of TIPS. Methods In this study, stool samples from 67 patients were collected preoperatively and 1 month postoperatively and metagenomic sequencing was performed to assess the composition of the gut microbiota. …”
Get full text
Article -
2611
The anti-depressive role of the Pei Yuan Kai Yu formula in cerebral small vessel disease based on gut microbiota
Published 2025-06-01“…BackgroundCerebral small vessel disease (CSVD), characterized by pathological changes in brain vessels, is a common cause of death in the elderly and often accompanied by depression, which significantly affects patients’ quality of life and rehabilitation; understanding its pathogenesis and developing innovative therapies are urgently needed, especially considering the role of the blood - brain barrier impairment and the gut - microbiota - gut - brain axis in this complex condition.MethodsDahl/SS rats were fed a diet containing 8% NaCl and were subjected to chronic unpredictable mild stress (CUMS) stimulation for 4 weeks. …”
Get full text
Article -
2612
Epigenetic signatures in surrogate tissues are able to assess cancer risk and indicate the efficacy of preventive measures
Published 2025-04-01“…Abstract Background In order to advance personalized primary cancer prevention, surrogate endpoint biomarkers in distant, easy to access tissues (i.e., field defect indicators) reflecting field cancerization in the organ at risk are essential. …”
Get full text
Article -
2613
The Potential of <i>Zanthoxylum acanthopodium</i> DC. as Immunomodulators: Formulation, Activity Testing, and Extract Profiling
Published 2025-07-01“…<b>Background/Objectives</b>: One of the plants found in Indonesian forests that has potential as an herbal medicine is andaliman (<i>Zanthoxylum acanthopodium</i> DC.). …”
Get full text
Article -
2614
Single-cell and spatial transcriptome analyses reveal MAZ(+) NPC-like clusters as key role contributing to glioma recurrence and drug resistance
Published 2025-06-01“…Abstract Background Temozolomide (TMZ) is an important chemotherapeutic agent for glioma treatment. …”
Get full text
Article -
2615
Enrichment of Cancer‐Associated Fibroblasts, Macrophages, and Up‐Regulated TNF‐α Signaling in the Tumor Microenvironment of CMS4 Colorectal Peritoneal Metastasis
Published 2025-01-01“…ABSTRACT Background Metastatic colorectal cancer (mCRC) is the main cause of CRC mortality, with limited treatment options. …”
Get full text
Article -
2616
Correction of Batch Effect in Gut Microbiota Profiling of ASD Cohorts from Different Geographical Origins
Published 2024-10-01“…Background: To date, there have been numerous metataxonomic studies on gut microbiota (GM) profiling based on the analyses of data from public repositories. …”
Get full text
Article -
2617
Fecal microbiota transplantation restores gut microbiota diversity in children with active Crohn’s disease: a prospective trial
Published 2025-03-01“…Abstract Background Clinical data on oral fecal microbiota transplantation (FMT), a promising therapy for Crohn’s disease (CD), are limited. …”
Get full text
Article -
2618
The association between plant-based diet indices and the risk of breast cancer: a case-control study
Published 2025-04-01“…Abstract Background Previous studies examining the relationship between plant-based diets and breast cancer (BrC) have provided conflicting evidence. …”
Get full text
Article -
2619
Perivascular Lymphocyte Clusters Induced by Gastric Subserous Layer Vaccination Mediate Optimal Immunity against Helicobacter through Facilitating Immune Cell Infiltration and Loca...
Published 2020-01-01“…Background. In situ vaccination-induced local inflammatory response resulted in the establishment of a pool of tissue-resident memory T (TRM) cells and new vessels after the resolution of inflammation. …”
Get full text
Article -
2620
Modern clinical portrait of ovarian cancer patient in the Novosibirsk region
Published 2025-03-01“…Background. Ovarian cancer is one of the most common malignant neoplasms of the female genital area. …”
Get full text
Article