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2581
Preparation and characterization of thermal neutron sensitive lithium doped polystyrene plastic scintillators
Published 2025-02-01“…BackgroundLithium-doped plastic scintillators possess the dual-mode detection capability for both fast and thermal neutrons, and combine the advantages of conventional plastic scintillators such as cost-effectiveness and the ability to fabricate in large sizes, have drawn much attention and shown great potential for thermal neutron detection in recent years.PurposeThis study aims to prepare large, trasparent polystyrene (PS) plastic scintillators doped with lithium methacrylate (LiME) via a thermal polymerization method, and to characterize their optical transmittance, luminescence, and pulse height spectrum response properties.MethodsThe composition, and structure of synthesized LiME were analyzed using Fourier transform infrared (FTIR) spectroscopy, Raman spectroscopy, and spectrophotometry. …”
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2582
Anxiety-related gut microbiota alterations in Parkinson’s disease: distinct associations compared to healthy individuals
Published 2025-06-01“…Background and objectivesAnxiety affects 25–49% of Parkinson’s disease (PD) patients, exacerbating non-motor symptoms and significantly reducing quality of life. …”
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2583
Self-Assembled Cannabigerol-Based Nanoparticles: Design, Synthesis, and Antiproliferative Activity
Published 2025-05-01“…<b>Background/Objectives:</b> Cannabigerol (CBG) is a non-psychoactive phytocannabinoid with significant therapeutic potential, showing emerging applications in drug delivery. …”
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2584
Can muscle synergies shed light on the mechanisms underlying motor gains in response to robot-assisted gait training in children with cerebral palsy?
Published 2025-02-01“…Abstract Background Children with cerebral palsy (CP) often experience gait impairments. …”
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2585
Choice of an artificial lung ventilation technique for the correction of mitral valve pathology from a mini-thoracotomy approach
Published 2025-06-01“…Background. In recent years, there has been a growing number of cardiac surgeries performed using minimally invasive techniques. …”
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2586
Single-cell sequencing combined with spatial transcriptomics reveals the characteristics of follicle-targeted inflammation patterns in primary cicatricial alopecia
Published 2025-07-01“…Abstract Background Primary cicatricial alopecia (PCA) causes irreversible hair loss due to immune-mediated hair follicle destruction. …”
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2587
Single-cell transcriptomic analyses reveal heterogeneity and key subsets associated with survival and response to PD-1 blockade in cervical squamous cell carcinoma
Published 2025-03-01“…Methods In this study, we characterized 50,649 cells obtained from the CSCC for single-cell RNA sequencing and integrated bulk sequencing data from The Cancer Genome Atlas (TCGA) and clinical samples to explore their cell composition, metabolic processes, signaling pathways, specific transcription factors, lineage tracking and response to immunotherapy. …”
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2588
The Efficacy of a Novel Type of Integrated Knife for Endoscopic Submucosal Dissection in Early Gastric Cancer
Published 2022-03-01“…Background/Aims This study aimed to compare the efficacy of a recently developed clear-cut knife with that of widely used knives for endoscopic submucosal dissection (ESD) in early gastric cancer (EGC). …”
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2589
Glycemic response to SSBs and ASBs: the role of mixed meals and individual variability
Published 2025-07-01“…Abstract Background While artificially sweetened beverages (ASBs) are widely reported to have minimal glycemic impact compared to sugar-sweetened beverages (SSBs), their effects in mixed meal conditions and individual variability in response remain poorly understood. …”
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2590
Impact of diet in shaping gut virome of grain-fed and grass-fed beef cattle revealed by a comparative metagenomic study
Published 2025-08-01“…Different feeding methods are likely to affect gut microbiota compositions and subsequently change microbial adaptation and cattle metabolism. …”
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2591
Targeted and Non-Targeted Metabolomic Evaluation of Cerebrospinal Fluid in Early Phase Schizophrenia: A Pilot Study from the Hopkins First Episode Psychosis Project
Published 2025-04-01“…Compared to peripheral compartments, cerebrospinal fluid (CSF) more closely reflects the chemical composition of brain extracellular fluid. Given that brain dysregulation may be more pronounced during the first episode of psychosis (FEP), we hypothesized that metabolomic analysis of CSF from FEP patients could reveal disease-associated biomarkers. (2) Methods: We recruited 15 patients within 24 months of psychosis onset (DSM-4 criteria) and 14 control participants through the Johns Hopkins Schizophrenia Center. …”
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2592
Age-Related Differences in the Appetite-Regulating Hormone Response to Exercise
Published 2025-07-01“…Background: Acute exercise alters appetite-regulating hormones like peptide tyrosine tyrosine (PYY), glucagon-like peptide-1 (GLP-1), and ghrelin, suppressing appetite and reducing food intake. …”
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2593
A Comprehensive Study Employing Computational Analysis and Mendelian Randomization Has Revealed the Impact of Key Genes on Liver Cancer
Published 2025-05-01“…We also used the CIBERSORT deconvolution method to evaluate immune cell composition in HCC tissues, followed by correlation studies examining relationships between our key genes of interest and various immune cell populations. …”
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2594
Improving genomic prediction accuracy for methane emission and feed efficiency in sheep: integrating rumen microbial PCA with host genomic variation using neural network GBLUP (NN-...
Published 2025-07-01“…Abstract Background Methane emissions from ruminant livestock pose a significant challenge to mitigating climate change. …”
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2595
Exploring the associations of gut microbiota with inflammatory and the early hematoma expansion in intracerebral hemorrhage: from change to potential therapeutic objectives
Published 2025-02-01“…BackgroundAlthough a great deal of research has explored the possibility of a systemic inflammatory response and dysbiosis of the gut microbiota after an intracerebral hemorrhage (ICH), the relationships between gut microbiota and blood inflammatory indicators as well as their role in the hematoma expansion following an early-stage mild-to-moderate ICH (emICH) remain unknown. …”
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2596
A Focus on the Role of Dietary Treatment in the Prevention of Retinal Dysfunction in Patients with Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency: A Systematic Review
Published 2025-03-01“…<b>Background</b>: Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) is an inborn error affecting fatty acid β-oxidation (FAO). …”
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2597
BLOOD-SUCKING MOSQUITOES (DIPTERA, CULICIDAE) OF THE LANDSCAPE PROVINCES OF THE STAVRPOLSKY KRAI-CARRIERS OF MALARIA
Published 2022-07-01“…No more than 12 species of blood-sucking mosquitoes can be considered background species, and the following species of mosquitoes-Anopheles hyrcanus, Anopheles maculipennis, Culex modestus, Cx.pipiens pipiens, Coquillettidia richardii and Aedes mosquitoes. …”
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2598
Feasibility and predictive factors on the completion of docetaxel plus S‐1 adjuvant chemotherapy in pathological stage III gastric cancer
Published 2025-01-01“…Abstract Background The standard adjuvant chemotherapy regimen for stage III gastric cancer is docetaxel plus S‐1 (DS) based on the results of the START‐II trials. …”
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2599
Unveiling the diagnostic and pro-inflammatory role of crohn’s disease: insights from 16 S-guided discovery and species-specific validation
Published 2025-07-01“…Abstract Background The rising incidence of Crohn’s disease (CD) in Asia underscores the need to explore its underlying mechanisms. …”
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2600
Repurposing of an inotropic drug dobutamine to enhance the production of human hematopoietic stem cells from human induced pluripotent stem cells
Published 2025-06-01“…Abstract Background Dobutamine hydrochloride (DH), a common inotropic drug used for heart failure, has recently been discovered to inhibit Yes-Associated Protein (YAP). …”
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