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2461
Studying the possibilities of pharmacological correction of hypoxia-induced pulmonary hypertension using a phenolic compound with a laboratory cypher KUD975
Published 2024-01-01“…The aim of our work was to study a pharmacological activity of a selective arginase-2 and thrombin inhibitor from a phenolic compounds group with a laboratory cypher KUD975 on a model of arterial pulmonary hypertension induced by hypoxia.Materials and methods. To simulate pulmonary hypertension (РН), animals were placed in a normobaric hypoxic chamber and subjected to 5 weeks of hypoxia with an oxygen content of 10% in the air. …”
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2462
University proceedings. Volga region. Natural sciences
Published 2024-11-01“…Background.We suppose a comprehensive description of macrophyte communities using both the traditional allocation of dominant and subdominant species and an integral assessment of species diversity using the natural logarithmic Shannon index, the Pielou evenness index, and the Simpson diversity index. …”
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2463
Metabolic state uncovers prognosis insights of esophageal squamous cell carcinoma patients
Published 2025-03-01“…Abstract Background Metabolite-protein interactions (MPIs) are crucial regulators of cancer metabolism; however, their roles and coordination within the esophageal squamous cell carcinoma (ESCC) microenvironment remain largely unexplored. …”
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2464
Distribution of Genetic Factors Associated with Severe COVID-19 in Ethnic Groups of the Eastern Caucasus
Published 2023-12-01“…Background. Previously, genetic markers rs11385942 G>GA and rs657152 C>A of disease severity were identified for COVID-19. …”
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2465
Data absenteeism in digital health technology research for older adults: a systematic review
Published 2025-05-01“…Abstract Background Digital health technologies are increasingly used to address healthcare challenges among older adults, yet concerns exist about data absenteeism—the underrepresentation of socioeconomically disadvantaged groups. …”
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2466
IL-6R blockade combined with immunosuppressants alleviates adult-onset Still’s disease through immune remodeling: a mass cytometry study
Published 2025-06-01“…Abstract Background Early administration of IL-6R blockade is effective in adult-onset Still’s disease (AOSD), but the underlying immune alterations during combined immunotherapy remain unclear. …”
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2467
Effects of Zinc Amino Acid Complex Supplementation on Welfare, Carcass Traits, Tibia Health, Meat Quality and Myopathies in Broilers
Published 2025-07-01“…ABSTRACT Background With the growing global demand for broiler meat, enhancing production efficiency is essential, and trace minerals like zinc (Zn) play a key role. …”
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2468
Dose-Dependent Effects of Turmeric (<i>Curcuma aromatica</i> S.) Starch on Colonic Fermentation in Rats
Published 2024-10-01“…Background; Turmeric starch (TS) has gained significant attention due to its potential health benefits. …”
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2469
Plasma pQTL and brain eQTL integration identifies PNKP as a therapeutic target and reveals mechanistic insights into migraine pathophysiology
Published 2024-11-01“…Abstract Background Migraine is a prevalent neurological disorder affecting 14.1% of the global population. …”
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2470
The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinogenesis
Published 2025-07-01“…BackgroundHelicobacter pylori is a globally prevalent bacterium associated with several gastrointestinal diseases, including peptic ulcers and gastric cancer. …”
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2471
Insights into variations of seasonal and daily soil temperatures under the effect of biocrusts in central-western Argentina
Published 2023-10-01“… Background and Aims: Biocrusts play an essential role on the earth’s surface and have a direct influence on soil parameters. …”
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2472
Scheme design for neutron beam shaping assembly based on D-Be compact fast neutron source
Published 2024-12-01“…BackgroundBoron Neutron Capture Therapy (BNCT) is a binary radiation therapy with strong targeting and high energy transfer line density at the cellular scale. …”
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2473
Diversity of high-molecular-weight glutenin subunits and evaluation of genetic similarities in spring bread wheats from different breeding centers
Published 2021-04-01“…Background. Glutenin is a storage protein in wheat seeds, important for the quality of bread prepared from wheat. …”
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2474
Predictive value of self-prioritized mobility factors on gait speed and life space in older nigerians: A cross-sectional study
Published 2025-06-01“…Background and Objectives: Eighty-two cognitive, environmental, financial, personal, physical, psychological, and social factors significantly influence mobility decline following hospital discharge. …”
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2475
Comparison of Rectal and Gastrointestinal Core Temperatures During Heat Tolerance Testing
Published 2025-06-01“…<i>Background and Objectives</i>: Military capability may be reduced in hot environments with individuals at risk of exertional heat stroke (EHS). …”
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2476
Formulation of W/O/W Emulsion-Based Chitosan-Alginate Microcapsules for Encapsulation of Cannabidiol and <i>A. annua</i> L. Extract Containing Luteolin and Apigenin: A Response Sur...
Published 2025-02-01“…<b>Background/Objectives:</b> Chitosan–alginate microcapsules were produced to encapsulate bioactive compounds from <i>Artemisia annua</i> L. extract (apigenin, luteolin) and cannabidiol (CBD). …”
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2477
The oro- and nasopharyngeal microbiota as a revolutionary perspective on mental disorders and related psychopathology: a systematic review and meta-analysis
Published 2025-07-01“…Dysbiosis in this region has been associated with systemic diseases, which may, in turn, contribute to disruptions in the gut microbiota. Methods In this study, we synthesized the current literature investigating differences in ONP microbial composition in people with various mental disorders, compared to healthy controls. …”
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2478
Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using Dictyophora indusiata water-insoluble polysaccharides in C57BL/6J mice
Published 2025-07-01“…BackgroundA healthy gut depends on a balance of commensal and probiotic bacteria, and prolonged and inappropriate clinical use of antibiotics can cause an imbalance in the gut flora, resulting in antibiotic-associated diarrhea (AAD). …”
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2479
Acid-Base Balance in Healthy Adults: Beneficial Effects of Bicarbonate and Sodium-Rich Mineral Water in a Randomized Controlled Trial: The BicarboWater Study
Published 2024-01-01“…Background. Noncommunicable diseases (NCDs) are a global health challenge. …”
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2480
Impact of Excess Adiposity on Cardiorespiratory Fitness in Children and Adolescents with Kawasaki Disease
Published 2025-02-01“…(1) Background: To assess the impact of excessive body fat on cardiorespiratory fitness (CRF) and coronary artery health in children and adolescents following acute Kawasaki disease (KD-CA). (2) Methods: A retrospective study of KD-CA patients (ages 8–16) who completed cardiopulmonary exercise testing (CPET) in the last five years. …”
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