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1841
Investigating potential links between gut microbiome, clinical parameters, and mortality in long-living male patients receiving multi-drug therapy
Published 2025-07-01“…Background and aimsMultimorbidity and polypharmacy are common in long-living patients and have been linked to alterations in gut microbiota. …”
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1842
Osteogenic Potential and Bone Matrix Maturity: Comparison of Demineralized Bone Matrix and P15 Polypeptide iFactor<sup>®</sup> in an In Vitro Study
Published 2025-05-01“…<i>Background and Objectives:</i> Demineralized bone matrix (DBM) is a widely used bone graft substitute due to its osteoconductive and osteoinductive properties. …”
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1843
Effect of perioperative individualized nutrition intervention on pancreatic surgery outcomes: a prospective single-center study
Published 2025-02-01“…Abstract Background There is currently a lack of reports on prospective randomized controlled trials (RCTs) focused on personalized nutritional support in pancreatic surgery. …”
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1844
Deciphering cellular heterogeneity and pathway dynamics in urinary samples: a UMAP-Based approach to understanding acute kidney injury
Published 2025-08-01“…Understanding the cellular heterogeneity in urine samples during AKI may provide insights into the underlying pathophysiological mechanisms and potential therapeutic targets.ObjectivesTo explore the cellular composition and gene expression patterns in urine samples from AKI and non-AKI conditions using Uniform Manifold Approximation and Projection (UMAP) to identify key cellular interactions and pathway activations related to AKI.MethodsWe utilized publicly available the dataset GSE180595 from the Gene Expression Omnibus (GEO) database. …”
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1845
Gegen Qinlian Decoction Ameliorated DSS-Induced Colitis by Attenuating Inflammation, Restoring Intestinal Mucosal Barrier and Modulating Gut Microbiota
Published 2025-06-01“…However, the specific mechanisms by which GQD exerts its effects remain poorly understood, limiting its application in UC treatment.Purpose: In this study, we utilized a dextran sodium sulfate-induced colitis model in mice to evaluate the efficacy of GQD and to elucidate its underlying mechanisms.Methods: Network pharmacology was employed to explore the potential targets and signaling pathways of GQD, which were subsequently validated using Western blot. …”
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1846
A 10‐Year Longitudinal Study of Muscle Morphology and Performance in Masters Sprinters
Published 2025-06-01“…ABSTRACT Background Both longitudinal and cross‐sectional studies have demonstrated that muscle mass, strength and power are lost with ageing. …”
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1847
Gut commensal Parabacteroides distasonis exerts neuroprotective effects in acute ischemic stroke with hyperuricemia via regulating gut microbiota-gut-brain axis
Published 2024-11-01“…Recent studies have highlighted the important role of gut microbiota in both hyperuricemia and AIS, but there is little available data on the relationship between gut microbiota and the pathogenesis of AIS with hyperuricemia (HAS). Methods Here we profiled the gut microbiota composition in 63 HAS patients and 269 non-HAS patients through 16s rRNA sequencing. …”
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1848
First Insights into the Fecal Metabolome of Healthy, Free-Roaming Giraffes (<i>Giraffa camelopardalis</i>): An Untargeted GCxGC/TOF-MS Metabolomics Study
Published 2024-10-01“…By using untargeted metabolomics via gas chromatography time-of-flight mass spectrometry (GCxGC/TOF-MS), this study primarily aims to provide results of the impact that external stimuli, such as supplemental feeding (SF) practices, seasonal variation and sex, might have on the fecal metabolome composition of healthy, free-roaming giraffes. Methods: Untargeted GCxGC/TOF-MS analysis was applied to the feces collected from thirteen giraffes (six males and seven females) from six different locations within the central Free State Province of South Africa over a period of two years. …”
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1849
Disentangling the gut microbiota of Aldabra giant tortoises of different ages and environments
Published 2025-06-01“…Background The gut microbiota plays a pivotal role in regulating the physiological functions of its host, including immunity, metabolism, and digestion. …”
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1850
Effects of High-Intensity Intermittent Training Combined with <i>Asparagus officinalis</i> Extract Supplementation on Cardiovascular and Pulmonary Function Parameters in Obese and...
Published 2025-06-01“…<b>Background:</b> High-intensity intermittent training (HIIT) has been proven to improve cardio-metabolic and respiratory health outcomes. …”
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1851
Gut microbiome signature in response to neoadjuvant chemoradiotherapy in patients with rectal cancer
Published 2025-04-01“…Emerging evidence suggests that the gut microbiome may influence the therapeutic efficacy of neoadjuvant chemoradiotherapy (CRT).ObjectiveThis study aimed to explore the dynamic changes in gut microbiome composition and metabolic pathways in rectal cancer patients undergoing CRT.MethodsPaired fecal samples were collected from rectal cancer patients pre- and post-CRT. 16S rRNA amplicon sequencing and proteomics analysis were conducted to investigate microbial and metabolic alterations.ResultsSignificant shifts in the microbiome were observed, with Fusobacterium, Subdoligranulum, Prevotella, Alloprevotella, and Bacteroides being enriched pre-CRT, while Streptococcus, Megamonas, Megasphaera, Escherichia-Shigella, and Olsenella became dominant post-CRT. …”
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1852
Exploring correlation between preoperative gut microbiota and PONV using 16S absolute quantitative sequencing: a prospective observational study
Published 2025-05-01“…BackgroundPostoperative nausea and vomiting (PONV) is a common complication following surgery. …”
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1853
Influence of manufacturing procedure on stability of Unguentum contra perniones preparations
Published 2005-01-01“…Background. Application of various technological procedures for the manufacture of officinal preparation ointment against chilblains (Unguentum contra perniones) produce essential variations in the quality and stability of the final product. …”
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1854
Stool consistency is significantly associated with pain perception.
Published 2017-01-01“…<h4>Background</h4>Commensal as well as pathogenic bacteria can influence a variety of gut functions, thereby leading to constipation and diarrhea in severe cases. …”
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1855
UPLC-ESI-QTRAP-MS-Based Metabolomics Revealed Changes in Biostimulant-Related Metabolite Profiles in <i>Zingiber mioga</i> Flower Buds During Development
Published 2025-05-01“…<b>Background:</b> The composition and abundance of biostimulants are important factors in the formation of the flavour and nutritional value of flower buds, as well as key factors influencing their growth and development. …”
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1856
Ontogenetic features of <I>Saposhnikovia divaricate</I> (Turcz.) Schischk. introduced into the environments of the Cis-Baikal Region
Published 2024-05-01“…Background. Saposhnikovia (Saposhnikovia Schischk.) is a monotypic genus occurring in the south of Eastern Siberia, the Far East, Mongolia, Manchuria, and Korea. …”
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1857
Distinct microbial signatures and their predictive value in recurrent acute pancreatitis: insights from 5-region 16S rRNA gene sequencing
Published 2025-02-01“…BackgroundRecurrent acute pancreatitis (RAP) poses significant clinical challenges, with 32.3% developing to chronic pancreatitis within 5 years. …”
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1858
The use of phosphorescence micromaterials for commercial textile products
Published 2024-01-01“…Phosphorescent textiles are less present as commercial products on the market. With this background the aim of the actual presentation is to investigate the properties of commercially available phosphorescent textile materials. …”
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1859
The effect of 6 weeks interval training with 90% vVO2max on atherogenic index, insulin resistance and beta-cell function in overweight men
Published 2018-10-01“…Background: High-intensity interval training (HIIT), compared with continuous training, can result in relatively more improvement in max exercise capacity, mitochondrial enzymes, and other cellular factors involved in energy metabolism. …”
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1860
The influence of retrobulbar adipose tissue volume upon intraocular pressure in obesity
Published 2013-01-01“…Background/Aim. It is known that glaucoma is associated with elevated intraocular pressure and obesity, yet the precise etiology remains unclear. …”
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