Game method to increase students' motivation to engage in elective disciplines in physical culture and sports by Inna N. Ovsyannikova, Konstantin G. Tomilin, Yulia A. Tumasyan, Yulia A. Vasilkovskaya, Ludmila V. Malygina

“…Background and Study Aim. A serious problem when using the play method in training sessions is the regulation of physical activity. …”
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Deep Reinforcement Learning-Based Distribution Network Planning Method Considering Renewable Energy by Liang Ma, Chenyi Si, Ke Wang, Jinshan Luo, Shigong Jiang, Yi Song

“…Distribution networks are an indispensable component of modern economic societies. Against the background of building new power systems, the rapid growth of distributed renewable energy sources, such as photovoltaic and wind power, has introduced many challenges for distribution network planning (DNP), including different source-load compositions, complex network topologies, and varied application scenarios. …”
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COPING MANUFACTURED TECHNIQUE OF SPINELL SLIP CAST ALL CERAMIC BY CONVENTIONAL METHODS AND CAD/CAM by Insani Hidayatin, Sri Redjeki Indiani, Rr. Dwiyanti Feriana Ratwita

“…Those steps all can be performed only by scanning, design, and milling by CAD/CAM methods. Besides that, coping result produced by CAD/ CAM methods has good accuracy due to spinell block utilization which has better homogenous composition.…”
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Assessing Differences and Implications of Two Methods for Calculating Outcomes in the Lower Quarter Y-Balance Test by Natalia Sokulska, Bartosz Zając, Paulina Katarzyna Gaj

“…Normalized reach (%) was calculated by dividing both the maximum and mean reach distances (cm) by the length of the lower limb (cm) and then multiplying the result by 100%. The composite score (%) was calculated by summing the maximum and mean reach distances in each direction, and then dividing the obtained values by three times the length of the lower limb, and finally multiplying the result by 100%.Results: The calculation method based on the maximum reach distance, as compared to the mean reach distances, yields significantly (p-value <0.001) higher values for all absolute (cm) and normalized (%) reaches, as well as composite score (%) in YBT-LQ.Conclusion: When comparing research findings using two calculation methods for YBT-LQ performance, it is important to consider that the maximum reach distances method yields higher values of 1.7-2.5 cm and 1.8-2.8% for absolute and normalized outcomes, respectively. …”
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Biomechanical evaluation of bispherical augments in acetabular defect reconstruction and comparative study of different fixation methods by Xiaoqi Zhang, Guoyuan Li, Min Chen, Zhe Ni, Zhengliang Luo, Xiaofeng Ji, Xifu Shang

“…Methods Nine composite hemipelvis specimens were prepared with a Paprosky II defect. …”
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Clinical and cost-effectiveness of paramedics working in general practice: a mixed-methods realist evaluation by Matthew Booker, Sarah Voss, Nicky Harris, William Hollingworth, Nouf Jeynes, Hazel Taylor, Kirsty Garfield, Helen Baxter, Jonathan Benger, Andy Gibson, Trudy Goodenough, Justin Jagosh, Kim Kirby, Cathy Liddiard, Alyesha Proctor, Sarah Purdy, Behnaz Schofield, Hannah Stott, Grace Scrimgeour, Nicola Walsh

“…Background General practice services are under pressure due increased demand. …”
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Janus kinase inhibitors in palmoplantar pustulosis: a mixed-methods feasibility (JAKPPPOT) trial protocol by Weiyu Ye, Suzie Cro, James B Galloway, Sarah Chapman, C H Smith, Kingsley Powell, Jonathan Barker, Ann Naylor, Helen McAteer, John Gregory, David Gleeson, April Qin, Jade Pizzato, Manpreet K Sagoo, Lucy Moorhead, Andrew E Pink, Richard Woolf, Satveer K Mahil

“…The primary outcome will be a composite assessment of feasibility across three domains: recruitment, adherence and acceptability, using a mixed-methods analysis approach. …”
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Development of a quality by design based eco-friendly RP-HPLC method for Ticagrelor and Aspirin by Shivani Jani, Ujashkumar Shah, Jayvadan Patel, Monika Dua

“…Objective: To design and validate a green, QbD-based RP-HPLC technique for simultaneous estimation of TICA and ASP in drug products. Methods: A 3-factor factorial design based on Response Surface Methodology (RSM) optimized important parameters: organic solvent composition, flow rate, and column temperature. …”
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Development and validation of a stability-indicating RP-HPLC method for tizanidine hydrochloride using DOE by Prasad Gunjal, Janki Patel

“…A full factorial design was implemented, optimizing mobile phase composition and flow rate as key method variables. Chromatographic separation was achieved using an Agilent Zorbax Bonus RP column (250 × 4.6 mm, 5 µm) with a mobile phase of 0.1% trifluoroacetic acid (TFA) and acetonitrile (65:35 v/v) at a 0.5 mL/min flow rate. …”
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Survey on the current practice of research ethics committees in the Czech academic environment: a mixed-methods study by Renata Veselska, Jan Sirucek, Josef Kure

“…Such research has never been conducted in Czechia. Methods This was a mixed-methods study, in which the online survey with closed and open-ended questions was chosen to explore the situation regarding ethics assessment of research involving human participants. …”
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Microbiome matters: how transplantation methods and donor origins shape the successful restoration of the seagrass Posidonia oceanica by Arnaud Boulenger, Tânia Aires, Aschwin H. Engelen, Gerard Muyzer, Michel Marengo, Sylvie Gobert

“…Abstract Background Posidonia oceanica forms extensive seagrass meadows in the Mediterranean Sea, providing key ecosystem services. …”
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The unresolved struggle of 16S rRNA amplicon sequencing: a benchmarking analysis of clustering and denoising methods by Mohamed Fares, Engy K. Tharwat, Ilse Cleenwerck, Pieter Monsieurs, Rob Van Houdt, Peter Vandamme, Mohamed El-Hadidi, Mohamed Mysara

“…Abstract Background Although 16S rRNA gene amplicon sequencing has become an indispensable method for microbiome studies, this analysis is not error-free, and remains prone to several biases and errors. …”
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Comparative Analysis of Generative Artificial Intelligence Systems in Solving Clinical Pharmacy Problems: Mixed Methods Study by Lulu Li, Pengqiang Du, Xiaojing Huang, Hongwei Zhao, Ming Ni, Meng Yan, Aifeng Wang

“… Abstract BackgroundGenerative artificial intelligence (AI) systems are increasingly deployed in clinical pharmacy; yet, systematic evaluation of their efficacy, limitations, and risks across diverse practice scenarios remains limited. …”
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Metagenomics reveals unique gut mycobiome biomarkers in major depressive disorder - a non-invasive method by Xuan Wang, Di Cao, Wei Chen, Jiaxin Sun, Huimin Hu

“…A significant proportion of previous research has concentrated on the study of gut bacterial communities, with relatively little attention paid to the link between gut mycobiome and depression.MethodsIn this research, we analyzed the composition and differences of intestinal fungal communities between major depressive disorder (MDD) and healthy controls. …”
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Subnational contribution to life expectancy and life span variation changes: Evidence from the United States by Wen Su, Alyson van Raalte, Jose Manuel Aburto, Vladimir Canudas-Romo

“…BACKGROUND: The US life expectancy has been stagnating in recent decades, and along with this, the time trends of life span variation have shown stagnation and even increases with respect to historical levels. …”
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Modified oil extraction of pristine and weathered synthetic polyurea microcapsules and polyethylene microplastics from soil by Eva-Maria Teggers, Svetlana Heck, Boris Meisterjahn, Markus Simon, Dieter Hennecke, Roman Heumann, Holger Egger, Philipp Dalkmann, Annika Jahnke, Andreas Schäffer

“…After MP isolation, precise MP quantification was facilitated by 14C-radiolabelling of the polymers, which enabled accurate mass balancing while eliminating potential interferences from background polymers. The modified oil extraction method, achieved extraction efficiencies of up to 75% of the applied radioactivity (AR), compared to a maximum efficiency of 62%AR using the conventional density extraction method combined with KOH. …”
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USE OF SIBUTRAMIN IN PHARMACEUTICAL DRUGS AND ANOREXIC DIETARY SUPPLEMENTS (REVIEW) by A. M. Sukhanova, I. B. Perova, G. M. Rodionova, K. I. Eller, V. I. Gegechkori

“…At the moment, a method for determining sibutramine in the composition of multicomponent drugs and dietary supplements to food of anorexigenic action is being developed, which will contribute to the development of pharmacy.…”
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Parametric Updating of Steel Strand Stay Cable Force Calculation Model Based on Response Surface Method by Shizhan Xu, Yinggang Ma, Hao Zhang

“…This method selects the central composite design in the response surface method. …”
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Comparison of alternative evidence summary and presentation formats in clinical guideline development: a mixed-method study. by Newton Opiyo, Sasha Shepperd, Nyokabi Musila, Elizabeth Allen, Rachel Nyamai, Atle Fretheim, Mike English

“…<h4>Background</h4>Best formats for summarising and presenting evidence for use in clinical guideline development remain less well defined. …”
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Parcel Segmentation Method Combined YOLOV5s and Segment Anything Model Using Remote Sensing Image by Xiaoqin Wu, Dacheng Wang, Caihong Ma, Yi Zeng, Yongze Lv, Xianmiao Huang, Jiandong Wang

“…Accurate land parcel segmentation in remote sensing imagery is critical for applications such as land use analysis, agricultural monitoring, and urban planning. However, existing methods often underperform in complex scenes due to small-object segmentation challenges, blurred boundaries, and background interference, often influenced by sensor resolution and atmospheric variation. …”
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