Prenatal exposure to organophosphate ester flame retardants and behavioral outcomes in early childhood in the Environmental influences on Child Health Outcomes (ECHO) cohort by Jiwon Oh, Lesliam Quirós-Alcalá, Xuan Li, Kurunthachalam Kannan, Wenjie Lyu, Lyndsay A. Avalos, Emily S. Barrett, Theresa M. Bastain, Jessie P. Buckley, Patricia Cintora, Lisa A. Croen, Anne L. Dunlop, Akhgar Ghassabian, Rima Habre, Julie B. Herbstman, Ixel Hernandez-Castro, Irva Hertz-Picciotto, Donghai Liang, Cindy T. McEvoy, Thomas G. O’Connor, Sheela Sathyanarayana, Susan L. Schantz, Rebecca J. Schmidt, Julie B. Schweitzer, Anne P. Starling, Heather E. Volk, Megan L. Woodbury, Tracey J. Woodruff, Qi Zhao, Yeyi Zhu, Deborah H. Bennett

“…Background: Prenatal exposure to organophosphate esters (OPEs) has been linked to neurotoxic effects in children; however, epidemiological evidence remains inconclusive. …”
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Determining optimal strategies for primary prevention of cardiovascular disease: a synopsis of an evidence synthesis study by Olalekan A Uthman, Lena Al-Khudairy, Chidozie Nduka, Rachel Court, Jodie Enderby, Seun Anjorin, Hema Mistry, G J Melendez-Torres, Sian Taylor-Phillips, Aileen Clarke

“…Background Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. …”
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Adaptation and psychometric properties of the Multigroup Ethnic Identity Inventory in secondary education by S. Suherman, T. Vidákovich

“…Methodology and research methods. The study involved 276 secondary school students (60.1% female; 39.9% male). …”
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Ultra-fast [18F]florbetapir PET imaging using the uMI Panorama PET/CT system by Xueqian Yang, Meiqi Wu, Menglin Liang, Haiqiong Zhang, Bo Li, Chenhui Mao, Liling Dong, Yuan Wang, Haiqun Xing, Chao Ren, Zhenghai Huang, Qingxiang Wen, Qi Ge, Zhengqing Yu, Feng Feng, Jing Gao, Li Huo

“…Abstract Background There is a need for faster amyloid PET scans to reduce patients’ discomfort, minimize movement artifacts, and increase throughput. …”
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Platelet-bound C4d, low C3 and lupus anticoagulant associate with thrombosis in SLE by John Conklin, Thierry Dervieux, Tyler O'Malley

“…Background Low C3 and lupus anticoagulant (LAC) are known risk factors for thrombosis in SLE. …”
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DOAC Score for Predicting Clinical Outcomes After Left Atrial Appendage Closure by Masahiko Asami, MD, Yu Horiuchi, MD, Jun Tanaka, MD, Daiki Yoshiura, MD, Masanori Taniwaki, MD, Kota Komiyama, MD, PhD, Hitomi Yuzawa, MD, PhD, Kengo Tanabe, MD, PhD, Mitsuru Sago, CE, Shuhei Tanaka, MD, PhD, Ryuki Chatani, MD, Toru Naganuma, MD, Yohei Ohno, MD, PhD, Tomoyuki Tani, MD, Hideharu Okamatsu, MD, Kazuki Mizutani, MD, PhD, Yusuke Watanabe, MD, PhD, Masaki Izumo, MD, PhD, Mike Saji, MD, PhD, Shingo Mizuno, MD, Daisuke Hachinohe, MD, Hiroshi Ueno, MD, PhD, Shunsuke Kubo, MD, Shinichi Shirai, MD, Masaki Nakashima, MD, Masanori Yamamoto, MD, PhD, Kentaro Hayashida, MD, PhD

“…Background: The direct-acting oral anticoagulant (DOAC) score has been validated for assessing the bleeding risk in patients with atrial fibrillation (AF). …”
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Dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy: a systematic review and individual participant data m... by Michelle E. Roh, Julie R. Gutman, Maxwell Murphy, Jenny Hill, Mywayiwawo Madanitsa, Abel Kakuru, Hellen C. Barsosio, Simon Kariuki, John P.A. Lusingu, Frank Mosha, Richard Kajubi, Moses R. Kamya, Don Mathanga, Jobiba Chinkhumba, Miriam K. Laufer, Eulambius Mlugu, Appolinary A.R. Kamuhabwa, Eleni Aklillu, Omary Minzi, Roland Nnaemeka Okoro, Ado Danazumi Geidam, John David Ohieku, Meghna Desai, Prasanna Jagannathan, Grant Dorsey, Feiko O. ter Kuile

“…Summary: Background: High-grade Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in east and southern Africa has prompted trials evaluating intermittent preventive treatment in pregnancy (IPTp) with dihydroartemisinin-piperaquine as an alternative to sulfadoxine-pyrimethamine. …”
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Single-cell transcriptome analysis revealed a suppressive tumor immune microenvironment in EGFR mutant lung adenocarcinoma by Lei Yang, Qing Zhou, Bo Zhang, Yi-Long Wu, Zhi-Hong Chen, Wen-zhao Zhong, Fen Wang, Yun-Ting He, Song Dong, Xue-Wu Wei, Wei-Dong Chen, Xiao-Rong Yang, Xue-Meng Shang

“…Hence, we initiated this study to describe the specific TME of EGFR-mutant lung adenocarcinoma (LUAD) from cellular compositional and functional perspectives to better understand the immune landscape of this most common subtype of NSCLC.Methods We used single-cell transcriptome sequencing and multiplex immunohistochemistry to investigate the immune microenvironment of EGFR-mutant and EGFR wild-type LUADs and determined the efficacy of immunotherapy. …”
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Prevalence, Characteristics, and Outcomes of Children With Congenital Heart Disease Undergoing Noncardiac Surgery in the Presence or Absence of COVID‐19 Infection During the Pandem... by David Faraoni, James A. DiNardo, Viviane G. Nasr

“…Background Children with congenital heart disease undergoing noncardiac surgery are at increased risk of perioperative complications. …”
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Effect of early tranexamic acid treatment on fatigue in patients with mild traumatic brain injury: data from the CRASH-3 clinical trial [version 3; peer review: 2 approved, 1 not a... by Temitayo Shokunbi, Haleema Shakur-Still, Raoul Mansukhani, Antonio Belli, Rizwana Chaudhri, Sabariah Faizah Jamaluddin, Amy Brenner, Lauren Frimley, Rashid Jooma, Ian Roberts

“…Background Each year world-wide about 65 million people sustain a mild traumatic brain injury (mTBI). …”
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The Diagnostic and Prognostic Value of the 12-Lead ECG in Arrhythmogenic Left Ventricular Cardiomyopathy by Leonardo Calò, MD, Cinzia Crescenzi, MD, Andrea Di Marco, MD, PhD, Francesca Fanisio, MD, Fabiana Romeo, MD, Alessio Gargaro, MSc, Annamaria Martino, MD, PhD, Chiara Cappelletto, MD, Marco Merlo, MD, Mattia Targetti, MD, Elisabetta Toso, MD, Federica Toto, MD, Maria Beatrice Musumeci, MD, Giacomo Tini, MD, Michele Ciabatti, MD, Matteo Stefanini, MD, Stefano Canestrelli, MD, Elisa Fedele, MD, Chiara Lanzillo, MD, PhD, Armando Fusco, MD, PhD, Federica Carla Sangiuolo, MD, PhD, Cinzia Radesich, MD, Maria Perotto, MD, Maurizio Pieroni, MD, Ruggiero Mango, MD, PhD, Alessio Gasperetti, MD, PhD, Camillo Autore, MD, Michela Casella, MD, PhD, Antonio Dello Russo, MD, PhD, Davide Stolfo, MD, PhD, Mikael Laredo, MD, PhD, Estelle Gandjbakhch, MD, PhD, Maddalena Graziosi, MD, PhD, Elena Biagini, MD, PhD, Costantina Catalano, MD, Ludovica Barile, MD, Fabrizio Drago, MD, Marianna Cicenia, MD, Anwar Baban, MD, PhD, Gemma Pelargonio, MD, PhD, Maria Lucia Narducci, MD, Federica Re, MD, Giovanni Peretto, MD, Elena Paiotti, MD, Carles Diez Lopez, MD, Iacopo Olivotto, MD, Fiorenzo Gaita, MD, Gianfranco Sinagra, MD, Giuseppe Novelli, MD, PhD

“…Background: Electrocardiographic findings in arrhythmogenic left ventricular cardiomyopathy (ALVC) have been limited to small studies. …”
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Hyperkalemia and the Risks of Adverse Cardiovascular Outcomes in Patients With Chronic Kidney Disease by Abiy Agiro, Fan Mu, Erin Cook, Alexandra Greatsinger, Jingyi Chen, Angela Zhao, Elaine Louden, Ellen Colman, Pooja Desai, Glenn M. Chertow

“…Methods and Results Adults with CKD stages 3b/4 with and without hyperkalemia were identified from Optum's deidentified Market Clarity Data (January 2016–August 2022). …”
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Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT by Neil McHugh, Laura Bojke, Mel Brooke Turfrey, Rachel Charlton, Myka Ransom, Laura C Coates, Howard Collier, Claire Davies, Emma Dures, Philip Helliwell, Jana James, Anya Lissina, Vishnu B Madhok, Alison L Nightingale, Jonathan Packham, Catherine Smith, Eldon Spackman, Cerys Tassinari, William Tillett, Sarah T Brown

“…Background Longitudinal observational studies suggest that patients who present early to secondary care with psoriatic arthritis have a better outcome. …”
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Thromboembolic Events in the Hemodialysis Setting: Understanding Risk Profiles and Cumulative Incidences to Inform Clinical Trial Design by Angelo Karaboyas, Junhui Zhao, Laszlo B. Tanko, Kristian Tore Joergensen, Akos F. Pap, Indranil Dasgupta, Masaomi Nangaku, Michel Jadoul, Roberto Pecoits‐Filho

“…Background People with kidney failure have a high risk of cardiovascular morbidity/death, including thromboembolic events. …”
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Transcatheter Aortic Valve Replacement and Surgical Aortic Valve Replacement Outcomes in Left Ventricular Assist Device Patients with Aortic Insufficiency by Aniket S Rali, Siva S Taduru, Lena E Tran, Sagar Ranka, Kelly H Schlendorf, Colin M Barker, Ashish S Shah, JoAnn Lindenfeld, Sandip K Zalawadiya

“…Background: Worsening aortic insufficiency (AI) is a known sequela of prolonged continuous-flow left ventricular assist device (LVAD) support with a significant impact on patient outcomes. …”
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Educational Attainment and the Effect of Intensive Blood Pressure Reduction: A Post Hoc Analysis of the SPRINT Study by Joshua Garfein, Akira Sekikawa, Andrew Mrkva, Djhenne Dalmacy, Jarett D. Berry, Yordanos M. Tiruneh, Jared W. Magnani

“…Background Hypertension is a major risk factor for cardiovascular disease (CVD). …”
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A Novel Phantom for Standardized Microcalcification Detection Developed Using a Crystalline Growth System by Dee H. Wu, Caroline Preskitt, Natalie Stratemeier, Hunter Lau, Sreeja Ponnam, Supriya Koya

“…Background/Objectives: The accurate detection of microcalcifications in mammograms is critical for the early detection of breast cancer. …”
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Registry for Evaluating Healthy Life Expectancy and Long-Term Outcomes after Catheter Ablation of Atrial Fibrillation in the Very Elderly (REHEALTH AF) study: rationale and design... by Kengo Kusano, Ayako Okada, Koji Miyamoto, Eizo Tachibana, Wataru Shimizu, Masato Murakami, Tomoo Harada, Kojiro Tanimoto, Takeshi Kato, Satoru Sakagami, Katsuhito Fujiu, Tatsuya Hayashi, Yasuo Okumura, Kazuhiro Satomi, Tomoyuki Shiozawa, Hideki Kobayashi, Michifumi Tokuda, Teiichi Yamane, Ryohsuke Narui, Seigo Yamashita, Satoru Miyanaga, Ikutaro Nakajima, Hidehira Fukaya, Hajime Kihara, Shiro Nakahara, Koichi Nagashima, Kenta Murotani, Shinya Suzuki, Ryuta Watanabe, Katsuaki Yokoyama, Hidemori Hayashi, Yu-ki Iwasaki, Yuhi Fujimoto, Yasushi Mukai, Koichiro Ejima, Takayuki Otsuka, Masaomi Kimura, Masahide Harada, Junjiroh Koyama, Hideharu Okamatsu, Mitsuru Takami, Morio Shoda, Kenichi Hiroshima, Tadashi Fujino, Keijiro Nakamura, Koji Kumagai, Yuji Watari, Mina Hatsuno, Kazuki Iso, Kazumasa Sonoda, Yoshiyasu Aizawa, Akio Chikata, Masaru Inoue, Hitoshi Minamiguchi, Nobuhiko Makino, Yoshinao Yazaki, Hideshi Aoyagi, Makoto Ichikawa, Hironori Haruta, Takafumi Hiro, Kimie Okubo, Ken Arima, Taiki Tojo, Yoshiaki Fukuda, Koji Oiwa, Tamami Fujiishi, Masashi Akabane, Norikazu Ishikawa, Haruna Tabuchi, Kenjiro Miyamoto, Hiroshi Mase

“…The question pertains especially to patients’ postablation quality of life (QoL) and long-term clinical outcomes.Methods and analysis We are initiating a prospective, registry-based, multicentre observational study that will include patients aged ≥80 years with non-valvular AF who choose to undergo treatment by catheter ablation and, for comparison, such patients who do not choose to undergo ablation (either according to their physician’s advice or their own preference). …”
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Pharmacist Use of a Population Management Dashboard for Safe Anticoagulant Prescribing: Evaluation of a Nationwide Implementation Effort by Geoffrey D. Barnes, Charity Chen, Rob Holleman, Joshua Errickson, F. Jacob Seagull, Michael P. Dorsch, Arthur L. Allen, Patrick Spoutz, Jeremy B. Sussman

“…Background Direct oral anticoagulants (DOACs) have complex dosing regimens and are often incorrectly prescribed. …”
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Pain and Sleep Disturbances are Associated with Post-stroke Anger Proneness and Emotional Incontinence by Adekola B. Ademoyegun, Wasiu A. Rasaq, Omotola I. Adelowokan, Victor A. Afolabi, Adebukola G. Ibitoye, Taofeek O. Awotidebe, Chidozie E. Mbada

“…We investigated the influence of composite and different components of post-stroke pain(PSP) as well as post-stroke sleep disorders (PSSD) on PSAP and PSEI.Methods: Cross-sectional data on PSAP, PSEI, PSP and PSSD were evaluated through validated instruments and structured interviewsfor a total of 185 community-dwelling stroke survivors attending two Nigerian tertiary health facilities. …”
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