Perceived technology usefulness for caregiving among unpaid caregivers: a National Cross-Sectional Study by Matthew Lee Smith, Matthew Lee Smith, Shinduk Lee, Malinee Neelamegam, Deborah Vollmer Dahlke, Deborah Vollmer Dahlke, Deborah Vollmer Dahlke, Jodi L. Southerland, Zachary G. Baker, Kris Pui Kwan Ma, Darina V. Petrovsky, Zahra Rahemi, Justine S. Sefcik, Juanita-Dawne R. Bacsu, Chung Lin Kew, Chung Lin Kew, Marcia G. Ory, Marcia G. Ory

“…BackgroundTechnological advancements have the potential to improve caregiving quality and alleviate caregiver burden by providing tools for real-time communication, monitoring, and care coordination. …”
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Single-cell RNA sequencing reveals immune microenvironment niche transitions during the invasive and metastatic processes of ground-glass nodules and part-solid nodules in lung ade... by Yi-Feng Ren, Qiong Ma, Xiao Zeng, Chun-Xia Huang, Jia-Li Ren, Fang Li, Jia-Jing Tong, Jia-Wei He, Yang Zhong, Shi-Yan Tan, Hua Jiang, Long-Fei Zhang, Heng-Zhou Lai, Ping Xiao, Xiang Zhuang, Peng Wu, Li-Ting You, Wei Shi, Xi Fu, Chuan Zheng, Feng-Ming You

“…Abstract Background Radiographically, ground-glass nodules (GGN) and part-solid nodules (PSN) in lung adenocarcinoma (LUAD) have significant heterogeneity in their clinical manifestations, biological characteristics, and prognosis. …”
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Efficacy and safety of venetoclax and azacitidine for acute myeloid leukemia in China: a real-world single-center study by Jie-Fei Bai, Ting Wang, Jiang-Tao Li, Chun-Li Zhang, Long Qian, Ya-Zi Yang, Xiao-Ya Yun, Jing-Jing Yin, Fei Zhao, Wei-Dong Ding, Bao-Li Xing, Shang-Yong Ning, Lei Pei, Xiao-Dong Xu, Hui Liu, Ru Feng

“…Abstract Background Venetoclax (VEN) and azacitidine (AZA) are used to treat patients with newly diagnosed acute myeloid leukaemia (AML) who are unfit for intensive chemotherapy and those with relapsed or refractory AML. …”
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Metabolic Status and Atrioventricular Block Risk: The Role of Physical Activity by Ho-Gi Chung, Pil-Sung Yang, Eunsun Jang, Daeun Joung, Daehoon Kim, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung

“…Methods: A total of 82,365 UK Biobank participants without a history of AVB or pacemaker implantation, and who were involved in accelerometer work-up, were chosen for the study population. …”
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Effect of obesity on myocardial tissue characteristics in patients with hypertrophic cardiomyopathy: a cardiovascular magnetic resonance-based study by Jie Wang, Lutong Pu, Jinquan Zhang, Ruihao Xu, Yang Li, Mengdi Yu, Yangjie Li, Jiajun Guo, Yuanwei Xu, Yu Kang, Yuchi Han, Yucheng Chen

“…Background: Obesity is associated with cardiac steatosis in healthy adults and is independently associated with increased left ventricular (LV) mass and could contribute to the progression of heart failure-related composite events in patients with hypertrophic cardiomyopathy (HCM). …”
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Efficacy and safety of dapagliflozin in patients hospitalized with COVID-19 with and without type 2 diabetes: a prespecified analysis of the DARE-19 randomized trial by Mohammad Abdel Jawad, Remo H. M. Furtado, Russell Esterline, Jan Oscarsson, Samvel B. Gasparyan, Gary G. Koch, Felipe Martinez, Omar Mukhtar, Subodh Verma, Anna Maria Langkilde, Philip Ambery, Shachi Patel, Kensey Gosch, Sheryl L. Windsor, Ronaldo V. P. Soares, Diogo D. F. Moia, Matthew Aboudara, Ali Javaheri, J. F. Kerr Saraiva, Lilia Nigro Maia, Otavio Berwanger, Andrew J. Sauer, Mikhail N. Kosiborod

“…Abstract Background Although several previous studies tested SGLT2 inhibitors in the setting of an acute, non-cardiovascular illness, detailed information on their efficacy and safety among participants with and without type 2 diabetes (T2D) from double-blind randomized trials is lacking. …”
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Cardiac arrest while using the toilet: not uncommon and associated with adverse resuscitation profile by Elizabeth D. Paratz, Carl Johann Hansen, Andre La Gerche, Dion Stub, Ziad Nehme, Ashanti Dantanarayana, Kelila Freedman, Andreas Pflaumer, Jodie Ingles, Bo Gregers Winkel, Jacob Tfelt-Hansen

“…Background: Out-of-hospital cardiac arrest (OHCA) on the toilet has been reported to be common and possibly driven by straining or vagal stimulus. …”
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A retrospective assessment of COVID-19 vulnerability index indicators and mortality rates pre-COVID-19 (2018–2020) and during COVID-19 (2020–2022) in a health and demographic surve... by Takwanisa Machemedze, Chodziwadziwa Whiteson Kabudula, Jean Juste Harrisson Bashingwa, Beth A. Tippett Barr, Nellie Myburgh, Sana Mahtab, Cleopas Hwinya, Stephen Tollman, Ziyaad Dangor, Shabir A. Madhi

“…Abstract Background Before COVID-19, knowledge on pandemic vulnerability and mortality in South Africa was largely limited to the context of HIV/AIDS. …”
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Artificial intelligence-enhanced comprehensive assessment of the aortic valve stenosis continuum in echocardiographyResearch in context by Jiesuck Park, Jiyeon Kim, Jaeik Jeon, Yeonyee E. Yoon, Yeonggul Jang, Hyunseok Jeong, Youngtaek Hong, Seung-Ah Lee, Hong-Mi Choi, In-Chang Hwang, Goo-Yeong Cho, Hyuk-Jae Chang

“…Summary: Background: Transthoracic echocardiography (TTE) is the primary modality for diagnosing aortic stenosis (AS), yet it requires skilled operators and can be resource-intensive. …”
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Global, regional, and national burden of maternal disorders, 1990–2021: a systematic analysis from the global burden of disease study 2021 by Jie Huang, Yuanyuan Man, Zan Shi, Xiaojie Fu, Wenhao Shi, Xiaoling Liang

“…Abstract Background Maternal morbidity and mortality, encompassing pregnancy-related complications and obstetric disorders, pose a persistent global health challenge with significant multigenerational consequences. …”
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Vaginal progesterone pessaries for pregnant women with a previous preterm birth to prevent neonatal respiratory distress syndrome (the PROGRESS Study): A multicentre, randomised, p... by Caroline A Crowther, Pat Ashwood, Andrew J McPhee, Vicki Flenady, Thach Tran, Jodie M Dodd, Jeffrey S Robinson, PROGRESS Study Group

“…<h4>Background</h4>Neonatal respiratory distress syndrome, as a consequence of preterm birth, is a major cause of early mortality and morbidity. …”
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Development and external validation of a risk prediction score (DASHI) for cardiovascular events following acute respiratory infections: derivation and validation retrospective coh... by Joseph J. Lee, Constantinos Koshiaris, Cynthia Wright-Drakesmith, Jennifer A. Davidson, Charlotte Warren-Gash, F.D. Richard Hobbs, James P. Sheppard

“…Summary: Background: Acute respiratory infections increase the short-term risk of myocardial infarction (MI) and stroke in primary care patients. …”
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Temporal prevalence and prognostic impact of diabetes mellitus and albuminuria in heart failure with preserved ejection fraction by Nousjka P. A. Vranken, Xinyu Li, Heleen Bouman, Sanne G. J. Mourmans, Anouk Achten, Arantxa Barandiarán Aizpurua, Hans-Peter Brunner-La Rocca, Christian Knackstedt, Vanessa P. M. van Empel, Jerremy Weerts

“…Abstract Background Most patients with heart failure with preserved ejection fraction (HFpEF) have a metabolic phenotype in which comorbidities including diabetes mellitus play an important role. …”
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Long-term exposure to outdoor fine particulate and physical activity with mortality and cardiovascular events: an analysis of the Prospective Urban Rural Epidemiology (PURE)-China... by Jun Hao, Zhiguang Liu, Bo Hu, Duolao Wang, Sumathy Rangarajan, Yang Wang, Chuangshi Wang, Lap Ah Tse, Weida Liu, Sidong Li, Minghai Yan, Qiujing Cai, Salim Yusuf, Wei Li

“…Summary: Background: Long-term exposure to PM2.5 and low physical activity are independently associated with an increased risk of cardiovascular disease (CVD). …”
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Exploring the therapeutic potential of Quercus ilex acorn extract in papillomavirus-induced lesions by Ana I. Faustino-Rocha, Maria João Pires, Maria João Neuparth, Helena Vala, Cármen Vasconcelos-Nóbrega, Irene Gouvinhas, Ana Novo Barros, Maria Inês Dias, Lillian Barros, Margarida M. S. M. Bastos, Lio Gonçalves, Luís Félix, Carlos Venâncio, Rui Medeiros, Rui Miguel Gil da Costa, Paula A. Oliveira

“…Background and Aim: Papillomaviruses (PVs) infections have been documented in numerous animal species across different regions worldwide. …”
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Intrapatient tacrolimus variability is associated with medical nonadherence among pediatric kidney transplant recipients by Tara B. Gavcovich, Tara B. Gavcovich, Vaka K. Sigurjonsdottir, Vaka K. Sigurjonsdottir, Marissa J. DeFreitas, Marissa J. DeFreitas, Claudia Serrano, Claudia Serrano, Esther Rivas, Esther Rivas, Migdalia Jorge, Migdalia Jorge, Wacharee Seeherunvong, Wacharee Seeherunvong, Chryso Katsoufis, Chryso Katsoufis, Wendy Glaberson, Wendy Glaberson, Melisa Oliva, Adela D. Mattiazzi, Carolyn Abitbol, Carolyn Abitbol, Jayanthi Chandar, Jayanthi Chandar

“…BackgroundLong-term survival of kidney allografts is limited by multiple factors, including nonadherence. …”
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Role of late gadolinium enhancement in the risk stratification of pediatric hypertrophic cardiomyopathy: based on a Chinese cohortResearch in context by Xingrui Chen, Wei Xiangli, Xuan Ma, Yun Tang, Jiaxin Wang, Zhixiang Dong, Kankan Zhao, Zhuxin Wei, Xi Jia, Pengyu Zhou, Yujie Liu, Yanyan Song, Chen Cui, Minjie Lu, Kai Yang, Xiuyu Chen, Shujuan Yang, Shihua Zhao

“…Summary: Background: Recently, late gadolinium enhancement (LGE) has been identified as an important risk factor in pediatric hypertrophic cardiomyopathy (HCM). …”
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Fixed-dose combination antihypertensive medications, adherence, and clinical outcomes: A population-based retrospective cohort study. by Amol A Verma, Wayne Khuu, Mina Tadrous, Tara Gomes, Muhammad M Mamdani

“…<h4>Background</h4>The majority of people with hypertension require more than one medication to achieve blood pressure control. …”
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Outcomes of transcatheter aortic valve replacement in younger low-risk patients: a comprehensive meta-analysis of efficacy and safety by António Rocha de Almeida, António Rocha de Almeida, António Rocha de Almeida, Maria Rita Lima, Maria Rita Lima, Daniel A. Gomes, Renato Fernandes, Eduardo Infante Oliveira, Eduardo Infante Oliveira, Pedro Araújo Gonçalves, Pedro Araújo Gonçalves, Rui Campante Teles, Rui Campante Teles, Manuel de Sousa Almeida, Manuel de Sousa Almeida, Lino Patrício

“…Background and aimsSevere aortic stenosis (AS) was traditionally managed with surgical aortic valve replacement (SAVR). …”
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Investigating the effectiveness of an intraoperative decision support guided fluid therapy intervention on postoperative outcome of high-risk patients undergoing high-risk abdomina... by Sean Coeckelenbergh, Amelie Delaporte, Damien Rousseleau, Jacques De Montblanc, Stephanie Roullet, Joanna Ramadan, Bernard Cholley, Alexandre Stibon, Emmanuel Weiss, Maria-Christina Kassab, Sylvain Diop, Elsa Manzi, Marco Pustetto, Guillaume Porta Bonette, Pierre Gregoire Guinot, Philippe Guerci, Domien Vanhonacker, Francois Martin Carrier, Brenton Alexander, Joseph Rinehart, David Boldt, Tristan Grogan, Maxime Cannesson, Jacques Duranteau, Lamiae Grimaldi, Bruno Pereira, Alexandre Joosten

“…Background: Inappropriate fluid administration can impact patient outcome. …”
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