Independent Risk Factors of Non-Resolution Mural Thrombus in ST-Segment Elevation Myocardial Infarction Patients with Left Ventricular Aneurysms by Meng Wang, Mengwan Li, Wenheng Liu, Jian Li, Dan Chen, Ziqing Wang, Qilong Guo, Shouling Mi, Junhua Ge

“…This study aimed to identify independent risk factors for MTLVA non-resolution. Methods: A total of 133 STEMI patients (mean age 62 ± 11 years, 80.5% male) with MTLVA, admitted to our department between 2014 and 2022, were included in this retrospective analysis. …”
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A co-created self-care and informal support intervention targeting women with gestational diabetes mellitus in northern Vietnam (VALID-II): a protocol for a two-arm non-randomised... by Ditte S. Linde, Hieu M. Le, Dung T. K. Vu, Ngoc-Anh T. Dang, Ai T. Nguyen, Tuc P. Vu, Xuan-Bai Nguyen, Cuong D. Nguyen, Dan W. Meyrowitsch, Jens Søndergaard, Christina A. Vinter, Ib C. Bygbjerg, Vibeke Rasch, Thanh D. Nguyen, Tine M. Gammeltoft, Dang K. Nguyen

“…Abstract Background Gestational diabetes mellitus (GDM) is a transitory form of diabetes that presents during pregnancy with frequent adverse maternal and neonatal health consequences if left untreated. …”
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Sex Differences in the Prognostic Value of Circulating Biomarkers in Patients Presenting With Acute Chest Pain by Gard Mikael Sæle Myrmel, MD, Nasir Saeed, Ole Thomas Steiro, MD, Hilde Lunde Tjora, MD, PhD, Jørund Langørgen, MD, PhD, Rune Oskar Bjørneklett, MD, PhD, Øyvind Skadberg, MD, Vernon Vijay Singha Bonarjee, MD, PhD, Øistein Rønneberg Mjelva, MD, Eva Ringdal Pedersen, MD, PhD, Kjell Vikenes, MD, PhD, Torbjørn Omland, MD, PhD, Kristin Moberg Aakre, MD, PhD

“…Background: Biomarkers are used for long-term risk prediction of cardiovascular (CV) events in patients presenting with suspected acute coronary syndromes. …”
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Characteristics and Outcomes of Older Patients Undergoing Protected Percutaneous Coronary Intervention With Impella by Philipp Jakob, Alexandra J. Lansky, Mir B. Basir, Michael J. Schonning, Batla Falah, Zhipeng Zhou, Wayne B. Batchelor, Arsalan Abu‐Much, Cindy L. Grines, William W. O'Neill, Barbara E. Stähli

“…Background In patients undergoing high‐risk percutaneous coronary intervention, Impella has become an important adjunctive tool to support revascularization. …”
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Salvage therapy containing sorafenib and donor lymphocyte infusion is associated with improved outcomes for FLT3 wild-type acute myeloid leukemia relapsing after allogeneic hematop... by Zhonghui Jiang, Ya Zhou, Yuxin Bai, Fang Dai, Menglin Fan, Tian Zhang, Danian Nie, Yunxin Zeng, Yirong Jiang, Ping Zhu, Zhiping Fan, Na Xu, Fen Huang, Ren Lin, Min Dai, Xiaojun Xu, Zhangkun Li, Hua Jin, Jing Sun, Qifa Liu, Li Xuan

“…Abstract Background There is no established standard treatment for acute myeloid leukemia (AML) patients with FLT3 wild-type relapsing after allogeneic hematopoietic stem cell transplantation (allo-HSCT). …”
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BMI-residualized data uncovers a cluster of people with type 2 diabetes and increased serum ferritin protected from cardiovascular disease by Laura Gallardo-Nuell, Jordi Blanch, Yenny Leal, Daniel E Coral, Talita Duarte-Salles, Giuseppe N. Giordano, Paul W. Franks, Ewan R. Pearson, Geltrude Mingrone, Carel W le Roux, Rafael Ramos, José Manuel Fernández-Real

“…This study aimed to identify distinct clusters of individuals with type 2 diabetes who have varying risks of MACE using a data-driven clustering approach. Methods This retrospective cohort study analyzed data from 49,506 individuals within a multicenter, population-based primary care registry in Catalonia, Spain. …”
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Delivery of care in high mortality hospital settings: a direct observational study examining 1848 h of neonatal nursing in KenyaResearch in context by Abdulazeez Imam, Michuki Maina, Jalemba Aluvaala, Vincent Kagonya, Onesmus Onyango, Fredrick Were, Sebastian Fuller, Kenneth Karumba, Mike English, David Gathara, Peter Mwangi, Lucy Kinyua, Lydia Thuranira, Virginia Njoroge, Ngina Mwangi, Loise Mwangi, Penina Musyoka, Zainab Kioni

“…Summary: Background: In resource-constrained countries, deploying better technologies is expected to improve neonatal care but little attention has been paid to the critical role of nurse staffing. …”
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Impact of awake prone positioning duration on intubation or mortality in COVID-19 patients with acute respiratory failure: secondary analysis of a randomized clinical trial by Qin Sun, Rui Zhang, Junyi Zhang, Jianfeng Xie, Yingzi Huang, Yi Yang, Haibo Qiu, Ling Liu, Hui Chen, the Chi-ARDS Net (Chinese ARDS Research Network)

“…Abstract Background Compared with shorter awake prone positioning (APP), prolonged APP (≥ 12 h daily) reduces the intubation rate in patients with COVID-19-related acute hypoxemic respiratory failure (AHRF). …”
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Elevated monocyte-to-high-density lipoprotein ratio is associated with increased risk of cognitive impairment and severe cerebral small vessel disease burden by Yueshan Zhao, Yueshan Zhao, Yueshan Zhao, Meixi Li, Meixi Li, Meixi Li, Meixi Li, Juan Zhang, Chao Wang, Mengyao Zhao, Qishuo Yang, Tianjun Wang, Peiyuan Lv, Peiyuan Lv, Peiyuan Lv, Peiyuan Lv, Peiyuan Lv

“…BackgroundMonocyte-to-high-density lipoprotein ratio (MHR), as a novel biomarker, has shown potential in predicting the onset and progression of various diseases. …”
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The role of left atrio-ventricular coupling index and left atrial ejection fraction in predicting onset of atrial fibrillation and adverse cardiac events in hypertrophic cardiomyop... by Parisi Francesca, La Franca Eluisa, Pistelli Lorenzo, Gentile Giovanni, Bellavia Diego, Nuzzi Vincenzo, Manca Paolo, Massimiliano Mulè, Zito Concetta, Di Bella Gianluca, Scipione Carerj, Cipriani Manlio, Francesco F. Faletra

“…Abstract Background Several predictors of atrial fibrillation (AF) onset in patients with hypertrophic cardiomyopathy (HCM) have been proposed, however, all of them showed limited accuracy. …”
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A novel therapy targeting the gut–liver axis for chronic hepatitis B: Ursodeoxycholic acid plus Bifidobacterium by Zhen Xun, Xiaobao Yao, Caorui Lin, Xinyao Yang, Yanfang Zhang, Xin Yang, Yujue He, Renquan Jiang, Yanping Lan, Yuchen Ye, Detai Ye, Shanjian Chen, Ke Ma, Wennan Wu, Siyi Xu, Bin Yang, Can Liu, Jing Chen, Qi Zheng, Qishui Ou

“…We aimed to assess the therapeutic efficacy of targeting the gut microbiota-bile acid (BA) axis using ursodeoxycholic acid (UDCA) combined with the probiotic Bifidobacterium to treat chronic hepatitis B (CHB). Methods: BA profiles were characterized by mass spectrometry, and gut microbiota composition was analyzed using 16S rRNA sequencing in patients with CHB and healthy controls (HCs). …”
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Impact of a Chronic Total Coronary Occlusion on the Incidence of Appropriate Implantable Cardioverter‐Defibrillator Shocks and Mortality: A Substudy of the Dutch Outcome in ICD The... by Anna van Veelen, Tom E. Verstraelen, Yvemarie B. O. Somsen, Joëlle Elias, Ivo M. van Dongen, Peter Paul H. M. Delnoy, Marcoen F. Scholten, Lucas V. A. Boersma, Alexander H. Maass, Sipke Strikwerda, Mehran Firouzi, Cornelis P. Allaart, Kevin Vernooy, Robert W. Grauss, Raymond Tukkie, Paul Knaapen, Aeilko H. Zwinderman, Marcel G. W. Dijkgraaf, Bimmer E. P. M. Claessen, Marit van Barreveld, Arthur A. M. Wilde, José P. S. Henriques

“…Background Chronic total coronary occlusions (CTO) substantially increase the risk for sudden cardiac death. …”
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Evaluation of real-time polymerase chain reaction for detection of Strongyloides stercoralis in immunocompromised patients in North India by Dr Abhishek Mewara, Ms. Nikita Sharma, Dr Gaurav Prakash, Dr Vignesh Pandiarajan, Dr Sahajal Dhooria, Dr Varun Dhir, Dr Surjit Singh, Dr Ritesh Agarwal

“…In this study, we evaluated real-time polymerase chain reaction (RT-PCR) for detection of Strongyloides stercoralis in immunocompromised patients in comparison with serology, microscopy and culture Methods. Methods & Materials: A total of 498 patients with immunosuppressive conditions and/or on steroids/cytotoxic medications from various specialties of our tertiary care hospital in North India were enrolled from December 2020 to March 2022 for collection of paired stool and serum samples on two occasions. …”
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Determining optimal timing of birth for women with chronic or gestational hypertension at term: The WILL (When to Induce Labour to Limit risk in pregnancy hypertension) randomised... by Laura A Magee, Katie Kirkham, Sue Tohill, Eleni Gkini, Catherine A Moakes, Jon Dorling, Marcus Green, Jennifer A Hutcheon, Mishal Javed, Jesse Kigozi, Ben W M Mol, Joel Singer, Pollyanna Hardy, Clive Stubbs, James G Thornton, Peter von Dadelszen, WILL Trial Study Group

“…<h4>Background</h4>Chronic or gestational hypertension complicates approximately 7% of pregnancies, half of which reach 37 weeks' gestation. …”
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Impact of Pan-Immune Inflammation Value on Short-Term Outcomes and Long-Term Prognosis in Patients with Type A Aortic Dissection by Cai H, Shourav, Shao Y, Shuangling S, Duan C, Zhang C, Wu QC

“…This study aims to investigate the relationship between preoperative PIV and both short-term and long-term outcomes in patients with acute TAAD.Methods: This retrospective study included acute TAAD patients who underwent surgical repair between September 2017 and December 2020. …”
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Elevated triglyceride-glucose index is a risk factor for cardiovascular events in adults with type 1 diabetes: a cohort study by Rosa Oh, Seohyun Kim, Sang Ho Park, Myunghwa Jang, So Hyun Cho, Ji Yoon Kim, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Gyuri Kim, Jae Hyeon Kim

“…Abstract Background The triglyceride-glucose (TyG) index is recognized as an indicator of insulin resistance and is linked to cardiovascular disease (CVD) in patients with type 2 diabetes. …”
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Candida and Bacterial Skin Colonisation of Critically-ill Patients in Two Tertiary Healthcare Facilities in Zambia by Prof Geoffrey Kwenda, Dr John Mwaba, Ms Chalwe Sokoni, Mr Christone Kaile, Ms Faith Kabansa, Mr Darlingtone Mwenya, Ms Tshiama Mirriam Mwamba, Ms Ruth Mpembe, Dr Sabelle Jallow, Ms Rudzani Mashau, Prof Nelesh Govender, Miss Chalwe Sokoni

“…This study aimed to investigate the prevalence of Candida and bacterial colonisation in critically ill patients in Zambia. Methods: In a Point-prevalence survey (PPS) for Candida and bacterial skin colonisation conducted on October 2 and 3, 2023, skin swab samples (composite axilla/groin) were collected from critically-ill patients who were admitted for at least 48 hours to two tertiary hospitals in Zambia. …”
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Candida skin colonization among critically-ill neonates, children and adults admitted to tertiary and district hospitals in Mozambique by Dr Sérgio Massora, Aquino Nhantumbo, Miriam Mwamba, Leocadia Vilanculos, Silondiwe Nzimande, Janeta Machai, Judice Miguel, Milton Kincardett, Corssino Tchavana, Anélsio Cossa, Eládio Alvaro, Sabelle Jallow, Rudzani C Mashau, Inácio Mandomando, Nelesh P Govender

“…Background: Pathogenic fungi are responsible for a largely silent epidemic, often hidden killers causing substantial morbidity and mortality in susceptible individuals. …”
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Effectiveness and risk of ARB and ACEi among different ethnic groups in England: A reference trial (ONTARGET) emulation analysis using UK Clinical Practice Research Datalink Aurum-... by Paris J Baptiste, Angel Y S Wong, Anna Schultze, Catherine M Clase, Clémence Leyrat, Elizabeth Williamson, Emma Powell, Johannes F E Mann, Marianne Cunnington, Koon Teo, Shrikant I Bangdiwala, Peggy Gao, Kevin Wing, Laurie Tomlinson

“…<h4>Background</h4>Guidelines by the National Institute for Health and Care Excellence recommend an angiotensin receptor blocker (ARB) rather than an angiotensin-converting enzyme inhibitor (ACEi) for the treatment of hypertension for people of African and Caribbean descent, due to an increased risk of angioedema associated with ACEi use observed in US trials. …”
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A 5-Year Follow-Up of Patient-Reported Outcome Measures Following External Beam Radiotherapy or Radical Prostatectomy in Localised Prostate Cancer by Rowan V. David, Peter L. Stapleton, Arman A. Kahokehr, Jason Lee, David I. Watson, John Leung, Michael E. O’Callaghan

“…<b>Background/Objectives</b>: Late toxicity following radiotherapy is common and compromises patient quality of life. …”
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