A scoring model integrating CXCL9, GDF15, FGF21, and NfL, predicts long-term mortality in type 2 diabetes: a retrospective study by Matilde Sbriscia, Sara Caccese, Francesca Marchegiani, Rina Recchioni, Giulia Matacchione, Chiara Giordani, Emanuele Francini, Stefano Salvioli, Maria Conte, Matteo Landolfo, Anna Rita Bonfigli, Federica Turchi, Jacopo Sabbatinelli, Fabiola Olivieri, Angelica Giuliani

“…Abstract Background Type 2 diabetes (T2D) is a chronic metabolic disorder associated with aging, systemic inflammation, and increased long-term mortality. …”
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Prognostic value of lipoprotein(a) for cardiovascular events after lower limb revascularization in diabetic patients with chronic limb-threatening ischemia by Federico Biscetti, Maria Margherita Rando, Maria Anna Nicolazzi, Flavia Angelini, Roberto Iezzi, Luis H. Eraso, Paul J. Dimuzio, Dario Pitocco, Massimo Massetti, Antonio Gasbarrini, Andrea Flex

“…Abstract Background Chronic limb-threatening ischemia (CLTI) presents a major clinical challenge in patients with Type 2 Diabetes Mellitus (T2DM), requiring lower extremity revascularization (LER) to mitigate adverse cardiovascular and limb outcomes. …”
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The Influence of Depression, Anxiety, and Stress on Ageism Among Undergraduates: Mediating Roles of Life Satisfaction, Gratitude, and Prosociality by Chen S, Wan Z

“…Following data cleaning, 1174 responses were included for analysis.Methods: Data were collected using online questionnaires. …”
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The effects of rhythm control strategies versus rate control strategies for atrial fibrillation and atrial flutter: A systematic review with meta-analysis and Trial Sequential Anal... by Naqash J Sethi, Joshua Feinberg, Emil E Nielsen, Sanam Safi, Christian Gluud, Janus C Jakobsen

“…<h4>Background</h4>Atrial fibrillation and atrial flutter may be managed by either a rhythm control strategy or a rate control strategy but the evidence on the clinical effects of these two intervention strategies is unclear. …”
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Proton Pump Inhibitor Use Following Esophageal Variceal Ligation and Its Impact on Clinical Outcomes: Real-World Data from the TriNetX Global Collaborative Network by Nisar Amin, Harleen Chela, Muhammad Faisal Mubarak, Mark Ayoub, Ebubekir Daglilar

“…<b>Background:</b> Proton pump inhibitors (PPIs) are frequently used after endoscopic variceal ligation (EVL) to reduce post-procedural bleeding, though studies have shown mixed results regarding their efficacy. …”
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Predicting Transvaginal Surgical Mesh Exposure Outcomes Using an Integrated Dataset of Blood Cytokine Levels and Medical Record Data: Machine Learning Approach by Mihyun Lim Waugh, Tyler Mills, Nicholas Boltin, Lauren Wolf, Patti Parker, Ronnie Horner, Thomas L Wheeler II, Richard L Goodwin, Melissa A Moss

“… Abstract BackgroundTransvaginal insertion of polypropylene mesh was extensively used in surgical procedures to treat pelvic organ prolapse (POP) due to its cost-efficiency and durability. …”
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Catalytic hydroprocessing of yellow dodolla oil using thermally stable and mesoporous AlPO4-18 supported β-Mo2C, Ni3C, and WC nanoparticles to produce bio-jet fuel by Zinnabu Tassew Redda, Steffen Kadow, Mirko Barz, Abubeker Yimam, Hartmut Wesenfeld, Daniel Brennecke, Asnakech Laß-Seyoum

“…Abstract Background The transition from fossil-derived jet fuels to sustainable aviation fuels represents one of the most viable strategies to decarbonize air transport and mitigate CO2 emissions generated by fossil fuel combustion. …”
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The impact of deprivation and neighbourhood food environments on home food environments, parental feeding practices, child eating behaviours, food preferences and BMI: The Family F... by Andrea D Smith, Alice Kininmonth, Kristiane Tommerup, David Boniface, Chiara Gericke, Tiffany Denning, Carolyn Summerbell, Christina Vogel, Clare Llewellyn

“…Abstract Background Childhood obesity inequalities in England persist despite targeted interventions focused on promoting healthy diets and food environments. …”
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Sodium-glucose cotransporter 2 inhibitors and cardiovascular events among patients with type 2 diabetes and low-to-normal body mass index: a nationwide cohort study by Yuichiro Mori, Toshiaki Komura, Motohiko Adomi, Ryuichiro Yagi, Shingo Fukuma, Naoki Kondo, Motoko Yanagita, O. Kenrik Duru, Katherine R. Tuttle, Kosuke Inoue

“…Abstract Background Patients with low-to-normal body mass index (BMI; < 25.0 kg/m2) were underrepresented in major randomized controlled trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors for type 2 diabetes. …”
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Preliminary evaluation of a mindfulness intervention program in women with long COVID dysautonomia symptoms by Elizabeth Vandenbogaart, Matthew Figueroa, Diana Winston, Steve Cole, Julienne Bower, Jeffrey J. Hsu

“…Background: The symptom burden for patients with Long COVID-associated dysautonomia is high, yet there are currently no effective treatments. …”
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The Efficacy and Safety of Ferric Carboxymaltose in Heart Failure with Reduced Ejection Fraction and Iron Deficiency: An Updated Systematic Review and Meta-Analysis of Randomized C... by Inderbir Padda, Sneha Annie Sebastian, Daniel Fabian, Yashendra Sethi, Gurpreet Johal

“…<b>Background:</b> Iron deficiency (ID) often coexists with heart failure (HF), and its prevalence increases with the severity of HF. …”
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Microbiome profiling reveals gut bacterial species associated with rapid lung function decline in people with HIV by Xiangning Bai, Xiangning Bai, Xiangning Bai, Sajan C. Raju, Sajan C. Raju, Andreas Dehlbæk Knudsen, Rebekka Faber Thudium, Nicoline Stender Arentoft, Marco Gelpi, Marco Gelpi, Safura-Luise Heidari, Ken M. Kunisaki, Ken M. Kunisaki, Karsten Kristiansen, Karsten Kristiansen, Johannes Roksund Hov, Johannes Roksund Hov, Susanne Dam Nielsen, Susanne Dam Nielsen, Susanne Dam Nielsen, Marius Trøseid, Marius Trøseid, Marius Trøseid

“…BackgroundPeople with HIV (PWH) have an increased risk of pulmonary comorbidities compared to people without HIV. …”
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Prognosis of IgA nephropathy patient with proteinuria remission by supportive therapy: cohort from screening failed Chinese patients in TESTING study by Yingman Guo, Sufang Shi, Jinghong Zhao, Caili Wang, Zhangsuo Liu, Shuxia Fu, Nan Chen, Guisen Li, Lihua Wang, Zhaohui Ni, Haitao Zhang, Lingyun Lai, Jicheng Lv, Hong Zhang

“…The long-term prognosis of these patients needs further investigation.Methods 112 screening failed patients in the TESTING study from 10 centers in China were enrolled in this retrospective study. …”
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Clinical outcomes of cancer-associated isolated distal deep vein thrombosis: a comparison between asymptomatic and symptomatic thrombosis—findings from the ONCO DVT Study by Yoshito Ogihara, Yugo Yamashita, Takeshi Morimoto, Nao Muraoka, Michihisa Umetsu, Yuji Nishimoto, Takuma Takada, Tatsuya Nishikawa, Nobutaka Ikeda, Kazunori Otsui, Daisuke Sueta, Yukari Tsubata, Masaaki Shoji, Ayumi Shikama, Yutaka Hosoi, Yasuhiro Tanabe, Ryuki Chatani, Kengo Tsukahara, Naohiko Nakanishi, Kitae Kim, Satoshi Ikeda, Toru Sato, Takeshi Kimura, Kaoru Dohi

“…Background: The risk of recurrent venous thromboembolism (VTE) in patients with isolated distal deep vein thrombosis (IDDVT) is generally low, particularly when IDDVT is asymptomatic. …”
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Cancer-associated fibroblasts-derived exosomal piR-35462 promotes the progression of oral squamous cell carcinoma via FTO/Twist1 pathway by Yushan Ye, Fan Wu, Bowen Li, Hanyu Ma, Lianxi Mai, Yu Peng, Xiaodi Feng, Xiao Tan, Min Fu, Yongmei Tan, Tianjun Lan, Ruixin Wang, Siqi Ren, Jinsong Li, Shaohai Chang, Shule Xie

“…Abstract Background Cancer-associated fibroblasts (CAFs) represent a crucial component of tumor stroma and play critical roles in cancer progression. …”
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Development and Validation of a Machine Learning Prediction Model for Textbook Outcome in Liver Surgery: Results From a Multicenter, International Cohort by Jane Wang, MD, Amir Ashraf Ganjouei, MD, MPH, Taizo Hibi, MD, PhD, Nuria Lluis, MD, PhD, Camilla Gomes, MD, Fernanda Romero-Hernandez, MD, Han Yin, BA, Lucia Calthorpe, MD, Yukiyasu Okamura, MD, PhD, Yuta Abe, MD, PhD, Shogo Tanaka, MD, PhD, Minoru Tanabe, MD, PhD, Zeniche Morise, MD, PhD, Horacio Asbun, MD, PhD, David Geller, MD, Mohammed Abu Hilal, MD, PhD, Mohamed Adam, MD, Adnan Alseidi, MD, EdM, International Hepatectomy Study Group, Alison Baskin, Annie Wong-On-Wing, Annie Yang, Devesh Sharma, Taisuke Imamura, Masanori Nakamura, Yuya Miura, Koki Hayashi, Masatsugu Ishii, Keita Shimata, Kazuya Hirukawa, Hiroki Ueda, June S. Peng, Lucas Thornblade, Kenzo Hirose, Kimberly Kirkwood, Eric Nakakura, Carlos Corvera, Ajay Maker

“…This study aimed to (1) develop a machine learning (ML) model that predicts the textbook outcome in liver surgery (TOLS) using preoperative variables and (2) validate the TOLS criteria by determining whether TOLS is associated with long-term survival after hepatectomy. Background:. Textbook outcome is a composite measure that combines several favorable outcomes into a single metric and represents the optimal postoperative course. …”
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Assessment of the German Version of Brief Assessment of Cognition in Schizophrenia (BACS) by Matin Mortazavi, Jakob Amon, Iris Jäger, Genc Hasanaj, Zahra Aminifarsani, Kristin Fischer, Matthias Gamer, Alkomiet Hasan, Richard S.E. Keefe, Gabriele Sachs, Peter Falkai, Daniel Keeser, Florian Raabe, Elias Wagner

“…Background: Cognitive impairments are a hallmark of schizophrenia-spectrum disorders (SSD), contributing to poor treatment outcomes and a key treatment target. …”
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A Data‐Driven Epigenetic Characterization of Morning Fatigue Severity in Oncology Patients Receiving Chemotherapy: Associations With Epigenetic Age Acceleration, Blood Cell Types,... by Caroline Le, Maureen Lewis, Carolyn S. Harris, Liam Berger, Esther Chavez‐Iglesias, Lisa Morse, Anatol Sucher, Ritu Roy, Adam Olshen, Marilyn J. Hammer, Steve Paul, Margaret Wallhagen, Raymond Chan, Michael Sayer, Sue Yom, Nam‐Woo Cho, Alexandre Chan, Jon Levine, Anand Dhruva, Christine Miaskowski, Yvette P. Conley, Kord M. Kober

“…ABSTRACT Background Moderate‐to‐severe fatigue commonly occurs in patients with cancer. …”
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Cost-effectiveness of bioimpedance-guided fluid management in patients undergoing haemodialysis: the BISTRO RCT by Mandana Zanganeh, John Belcher, James Fotheringham, David Coyle, Elizabeth J Lindley, David F Keane, Fergus J Caskey, Indranil Dasgupta, Andrew Davenport, Ken Farrington, Sandip Mitra, Paula Ormandy, Martin Wilkie, Jamie H Macdonald, Ivonne Solis-Trapala, Julius Sim, Simon J Davies, Lazaros Andronis

“…Background The BioImpedance Spectroscopy to maintain Renal Output randomised controlled trial investigated the effect of bioimpedance spectroscopy added to a standardised fluid management protocol on the risk of anuria and preservation of residual kidney function (primary trial outcomes) in incident haemodialysis patients. …”
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Optimal Definition and Risk Stratification in Prediabetes With Stable Coronary Heart Disease: A Prospective Cohort Study by Chenxi Song, Zheng Qiao, Jiaxi Cheng, Yuze Zhang, Weida Liu, Sheng Yuan, Jining He, Yanjun Song, Xiaohui Bian, Zhangyu Lin, Rui Fu, Chunyue Wang, Qianqian Liu, Lei Feng, Jin Tao, Kefei Dou

“…Background The optimal definition and risk stratification approach to identify high‐risk patients with prediabetes and stable coronary heart disease has not been well studied to date. …”
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