Prior metabolic surgery attenuates the weight-loss efficacy of liraglutide in patients with mild obesity by Yuqin Ouyang, Yuqin Ouyang, Xinyue Xiang, Xinyue Xiang, Xinyun Hu, Xinyun Hu, Xuehui Chu, Wenjuan Tang, Wenjuan Tang, Wenhuan Feng, Wenhuan Feng, Wenhuan Feng

“…BackgroundLiraglutide effectively manages mild obesity, but individual weight loss outcomes vary significantly. …”
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Associations between triglyceride glucose-body mass index and 30-day mortality in patients with hemorrhagic stroke: analysis of the MIMIC-IV database by Yuexin Lu, Yuexin Lu, Enjie Song, Enjie Song, Ruilin Chen, Ruilin Chen, Long Jing, Long Jing, Jiahao Tang, Jiahao Tang, Shunan Shi, Shunan Shi, Ming Wang, Ming Wang, Ming Wang, Ming Wang, Shu Wan, Shu Wan, Shu Wan, Shu Wan

“…BackgroundHemorrhagic stroke (HS), accounting for over 40% of stroke-related deaths, imposes a severe global health burden due to high mortality and disability rates. …”
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Very low urinary marinobufagenin excretion reflects a high risk of disease progression in non-advanced CKD by Davide Bolignano, Davide Bolignano, Marta Greco, Marta Greco, Loredana Tripodi, Mario D’Agostino, Paola Cianfrone, Roberta Misiti, Roberta Misiti, Sara Pugliese, Mariateresa Zicarelli, Michela Musolino, Michela Musolino, Daniela Patrizia Foti, Daniela Patrizia Foti, Michele Andreucci, Michele Andreucci, Giuseppe Coppolino, Giuseppe Coppolino

“…BackgroundChronic kidney disease (CKD) has now reached pandemic proportions but risk prediction towards end-stage kidney disease (ESKD) remains challenging. …”
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Deprescribing anticholinergics to preserve brain health: reducing the risk of dementia through deprescribing (R2D2): study protocol for a randomized clinical trial by Noll L. Campbell, Richard J. Holden, Sujuan Gao, Frederick W. Unverzagt, Kathleen A. Lane, Allie Carter, Addison B. Harrington, Sneha Manoharan, Neha Manoharan, Danielle L. Rosenthal, Christopher Pitts, Kathryn Pelkey, Emily Papineau, David M. Lauck, Noha Keshk, Khalid Alamer, Hussein Khalil, Malaz A. Boustani

“…Abstract Background Older adults commonly experience chronic medical conditions and are at risk of cognitive impairment as a result of age, chronic comorbidity, and medications prescribed to manage multiple chronic conditions. …”
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Platelet-rich plasma and dextrose prolotherapy in osteoarthritis knee by Yagya Parna Vohra, Afroz Ahmed Khan, Yesh Veer Singh, Abhishek Pandey, Abhinav Srivastava, Imran Shakeel Khan, Neeraj Singh

“…Background: A prevalent but little-understood ailment is osteoarthritis (OA) knee. …”
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Serum NT-ProBNP/Chloride Ratio Predicts Adverse Cardiovascular Outcomes in Patients with Acute Heart Failure by Victor José Leal-Alcántara, Eder González-Macedo, Ana Cristina Maldonado-May, Alberto Santiago-Hernández, Eder Jonathan Amaro-Palomo, Sarai Hernandez-Pastrana, Anna Elisa Adib-Gracia, Rodrigo Gopar-Nieto, Daniel Sierra-Lara Martínez, José Luis Briseño-De la Cruz, Héctor González-Pacheco, Alexandra Arias-Mendoza, Diego Araiza-Garaygordobil

“…<b>Background:</b> Heart failure (HF) is a public health issue. …”
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Randomized trial of ultraviolet irradiation units installed in homes of children and adolescents with asthma by Jonathan A. Bernstein, MD, Anand Seth, PhD, Marepalli Rao, PhD, Janyce C. Katz, JD, Umesh Singh, MD, PhD, William Greisner, MD, Michelle Lierl, MD, Benjamin Prince, MD, Kunjana Mavunda, MD, MPH, Cheryl K. Bernstein, RN, BS, CRCC, Tianyuan Guan, PhD, Amy J. Nation, DO, Amanda K. Rudman Spergel, MD, Alkis Togias, MD, Mark Glazman, PhD

“…Background: Asthma management involves medications with environmental control, but patient adherence to the latter is poor. …”
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Prognostic Implication of Computational Angiography–Derived Fractional Flow Reserve in Patients With Nonobstructive Coronary Artery Disease by Yik‐Ming Hung, Hao‐Chen Xuan, Qing‐Wen Ren, Jia‐Yi Huang, Si‐Yeung Yu, Yi‐Kei Tse, Jing‐Nan Zhang, Wen‐Li Gu, Ran Guo, Calvin Ka‐Lam Leung, Kai‐Hang Yiu

“…Background Risk stratification of patients with symptomatic nonobstructive coronary artery disease remains uncertain. …”
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Predictive value of the systemic inflammation grade for overall survival in patients with colorectal cancer after surgery: outperforming NLR and mGPS by Jianing Wang, Yujun Liu, Wenliang Jiang, Dongli Zhang, Chao Cheng, Cuixia Liu, Zhibin Zhao, Honggang Wang

“…The Systemic Inflammation Grade (SIG), integrating neutrophil-to-lymphocyte ratio (NLR) and modified Glasgow Prognostic Score (mGPS), was proposed as a composite marker to refine risk assessment.MethodsThis retrospective study analyzed 263 CRC patients undergoing R0 resection (2015–2019). …”
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Comparison of right ventricular function and clinical outcomes in type 2 diabetes patients with and without obstructive coronary artery disease: insights from a CMR study by Jin Wang, Wei-Feng Yan, Ke Shi, Hua-Yan Xu, Shi-Qin Yu, Ying-Kun Guo, Li Jiang, Yue Gao, Yu-Jiang, Xue-Ming Li, Yuan Li, Zhi-Gang Yang

“…Abstract Background Obstructive coronary artery disease (OCAD) marks a high-risk group within patients with type 2 diabetes mellitus (T2DM), underscoring the need for tailored prevention and management strategies. …”
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Gypenosides Alleviate Hyperglycemia by Regulating Gut Microbiota Metabolites and Intestinal Permeability by Rong Wang, Xue-Feng Liu, Kuan Yang, Li-Li Yu, Shao-Jing Liu, Na-Na Wang, Yun-Mei Chen, Ya-Qi Hu, Bei Qin

“…The aim of this study is to clarify the molecular mechanisms of Gps in ameliorating glucose dysregulation. <b>Methods</b>: Qualitative and quantitative analyses on the chemical components of Gps were performed, respectively. …”
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Prevalence and risk factors of self-medication with antibiotics in the general population of Tehran—a population-based study by Keyvan Karimi, Yosra Azizpour, Maryam Shafaati, Erta Rajabi, Maryam Zare, Arash Seifi, Ozra Tabatabaei-Malazy, Samaneh Akbarpour, Mahnaz Khalafehnilsaz

“…Abstract Background Given the ongoing global threat of antimicrobial resistance (AMR), largely fueled by self-medication with antibiotics (SMA), this study offers important insights from southern Tehran—an underrepresented region in national data—regarding the prevalence and determinants of SMA. …”
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mHealth intervention "ImTeCHO" to improve delivery of maternal, neonatal, and child care services-A cluster-randomized trial in tribal areas of Gujarat, India. by Dhiren Modi, Nishith Dholakia, Ravi Gopalan, Sethuraman Venkatraman, Kapilkumar Dave, Shobha Shah, Gayatri Desai, Shamim A Qazi, Anju Sinha, Ravindra Mohan Pandey, Ankit Anand, Shrey Desai, Pankaj Shah

“…<h4>Background</h4>The coverage of community-based maternal, neonatal, and child health (MNCH) services remains low, especially in hard-to-reach areas. …”
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Plasma microRNA signatures of aging and their links to health outcomes and mortality: findings from a population-based cohort study by Lieke M. Kuiper, Michelle M. J. Mens, Julia W. Wu, Jaap Goudsmit, Yuan Ma, Liming Liang, Albert Hofman, Trudy Voortman, M. Arfan Ikram, Jeroen G. J. van Rooij, Joyce B. J. van Meurs, Mohsen Ghanbari

“…Abstract Background MicroRNAs are small non-coding RNAs that regulate gene expression post-transcriptionally and show differential expression in various tissues with aging phenotypes. …”
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Passive immunotherapy for adults hospitalized with COVID-19: An individual participant data meta-analysis of six randomized controlled trials. by Kirk U Knowlton, Lianne K Siegel, Christina E Barkauskas, Sanjay Bhagani, Nila J Dharan, Edward M Gardner, Robert L Gottlieb, Marie Helleberg, Helene C Highbarger, Thomas L Holland, Christian Kjer Heerfordt, Susana Lazarte, Lindsey M Leither, Joseph Lutaakome, Magdalena Ardelt, Eleftherios Mylonakis, Sean W X Ong, Jeffrey Scott Overcash, Hassan Taha, Phyllis C Tien, Barbara W Trautner, David Vallee, Amy C Weintrob, Giota Touloumi, Abdel G Babiker, STRIVE ACTIV-3/TICO Study Group

“…<h4>Background</h4>Anti-SARS-CoV-2 monoclonal antibodies (mAb) reduce the risk of hospitalization in outpatients with mild-to-moderate COVID-19. …”
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The cross-sectional association between cardiometabolic index and abdominal aortic calcification in U.S. adults: evidence from NHANES 2013–2014 by Jiawei Peng, Jijun Wu, Xitu Luo, Chengyu Yang, Shian Wu, Wenjun Liu, Wenjun Liu, Yuanhao Feng

“…BackgroundThe cardiometabolic index (CMI) is a novel composite measure that integrates assessments of abdominal adiposity and lipid profiles. …”
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Total bilirubin as a marker for hemolysis and outcome in patients with severe ARDS treated with veno-venous ECMO by Victoria Bünger, Mario Menk, Oliver Hunsicker, Alexander Krannich, Felix Balzer, Claudia D. Spies, Wolfgang M. Kuebler, Steffen Weber-Carstens, Jan A. Graw

“…Abstract Background Hemolysis is a common complication in critically ill patients with sepsis, acute respiratory distress syndrome (ARDS) or therapy with extracorporeal membrane oxygenation (ECMO). …”
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Prognostic value of a lncRNA signature in early-stage invasive breast cancer patients by Rong Guo, Xiting Wang, Yinju Yang, Jiaying Zou, Ming Li, Zeying Li, Yuan Yan, Nan Lan, JianYun Nie, Yiyin Tang, Guojun Zhang

“…Abstract Background Existing staging approaches fall short in precisely forecasting the likelihood of recurrence and survival outcomes among patients undergoing surgery for early-stage breast cancer (EBC). …”
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Non-high density lipoprotein cholesterol/high density lipoprotein cholesterol is L-shaped associated with all-cause mortality and U-shaped with cardiovascular mortality in hyperten... by Meiqian Chen, Meiqian Chen, Li Zhang, Qian Liu, Qingxin Gu, Shuhui Yu, Guanzhen Lu, Guanzhen Lu

“…The relationship between the novel composite lipid metric, NHHR, and all-cause and cardiovascular mortality in hypertensive patients remains unknown and warrants further investigation.MethodsWe analyzed data from 5,561 hypertensive participants in the National Health and Nutrition Examination Survey (NHANES) spanning from 1999 to 2018. …”
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Vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative Age-Related macular degeneration (TIGER): study protocol... by Timothy L. Jackson, Catey Bunce, Riti Desai, Jost Hillenkamp, Chan Ning Lee, Noemi Lois, Tunde Peto, Barnaby C. Reeves, David H. Steel, Rhiannon T. Edwards, Jan C. van Meurs, Hatem Wafa, Yanzhong Wang

“…Abstract Background Neovascular (wet) age-related macular degeneration (AMD) can be associated with large submacular haemorrhage (SMH). …”
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