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4501
Enhancing retention and quality of tissue stromal vascular fraction graft with globo H ceramide
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4502
Impact of antihypertensive drug classes on cardiovascular outcomes: insights from the STEP study
Published 2025-07-01“…Abstract Background The optimal class of antihypertensive drugs for reducing cardiovascular risk remains unclear. …”
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4503
Relationship Among Macronutrients, Dietary Components, and Objective Sleep Variables Measured by Smartphone Apps: Real-World Cross-Sectional Study
Published 2025-01-01“… BackgroundFew studies have explored the relationship between macronutrient intake and sleep outcomes using daily data from mobile apps. …”
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4504
Dynamic Lipid–Glycaemic Index and Inflammation—Endothelial Shifts and Fetal Aortic Wall Thickening: A Repeated-Measures Gestational Phenotyping Study
Published 2025-05-01“…<i>Background and Objectives</i>: Maternal dyslipidaemia and low-grade inflammation are recognised drivers of in utero vascular remodelling, yet composite dynamic markers that integrate lipid–glycaemic, inflammatory and endothelial signals have not been evaluated. …”
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4505
Thyroid Feedback Quantile-based Index correlates strongly to renal function in euthyroid individuals
Published 2021-01-01“…Background Previous studies have reported a negative relationship between thyroid-stimulating hormone (TSH) and renal function in euthyroid individuals, but others have found that higher free thyroxine (FT4) was associated with an increased risk of chronic kidney disease. …”
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4506
Obstructive sleep apnea syndrome in polycystic ovary syndrome: a systematic review and meta-analysis
Published 2025-04-01“…BackgroundPolycystic ovary syndrome (PCOS) has been associated with a high prevalence of obstructive sleep apnea syndrome (OSAS). …”
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4507
Prognostic Impact of Anemia in Patients with Significant Mitral Regurgitation: A Multicenter Cohort Study
Published 2025-04-01“…This study sought to investigate the prevalence of anemia in patients with significant mitral regurgitation (MR), as well as its association with outcomes.Methods: A total of 4339 patients with moderate or greater MR in the China Valvular Heart Disease study were included in this analysis. …”
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4508
Association between red blood cell distribution width-to-albumin ratio and all-cause mortality in intracerebral hemorrhage
Published 2025-06-01“…BackgroundIntracerebral hemorrhage (ICH) remains a devastating cerebrovascular condition, marked by high fatality and limited availability of prognostic tools. …”
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4509
Impact of Medical Conditions and Area Deprivation on Fundraising Success in Online Crowdfunding: Cross-Sectional Study
Published 2025-07-01“… Abstract BackgroundWeb-based crowdfunding is commonly used to defray medical expenses, but it is not fully known which factors determine fundraising success. …”
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4510
Impact of Additional Active Treatment for Prostate Cancer on Health-related Quality of Life of Men: Results from the EUPROMS 2.0 1-year Follow-up Survey
Published 2025-01-01“…Acknowledging the importance of collecting quality of life (QoL) follow-up data, a 1-yr follow-up (1yrFU) study was conducted to assess the effect of additional PCa treatment on QoL. Methods: Men with PCa who participated in the EUPROMS 2.0 survey and indicated that they were open to collection of a follow-up measurement were reinvited to complete the 1yrFU survey. …”
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4511
Systematic proteomic and small RNA profiling of extracellular vesicles from cattle infected with a naturally occurring buparvaquone-resistant strain of Theileria annulata and from...
Published 2025-06-01“…Abstract Background Extracellular vesicles (EVs) play a pivotal role in host-parasite interactions, particularly in facilitating parasite pathogenesis and immune modulation, and are crucial mediators of intercellular communication. …”
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4512
Impact of systemic immune inflammation index and systemic inflammation response index on all-cause and cardiovascular mortality in cardiovascular-kidney-metabolic syndrome
Published 2025-07-01“…Abstract Background The cardiovascular-kidney-metabolic (CKM) syndrome is a systemic condition defined by multifaceted interactions among metabolic risk factors, chronic kidney disorder, and cardiovascular diseases. …”
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4513
Atrial fibrillation or flutter in patients undergoing stem cell transplantation, in-hospital and post-discharge outcomes in a large nationwide sample across the United States
Published 2025-07-01“…Abstract Background Stem Cell Transplantation (SCT) is a cornerstone therapy in managing several malignant and benign hematological conditions. …”
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4514
Comparative cardiovascular outcomes of aripiprazole vs. risperidone in patients with type 2 diabetes and schizophrenia: a retrospective cohort study
Published 2025-07-01“…BackgroundIndividuals with schizophrenia have substantially elevated cardiovascular morbidity and mortality, a disparity further exacerbated by coexisting type 2 diabetes mellitus (T2DM). …”
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4515
Correlation of changes in inflammatory and collagen biomarkers with durable guselkumab efficacy through 2 years in participants with active psoriatic arthritis: results from a phas...
Published 2024-10-01“…Guselkumab-randomized participants with available serum biomarker data (randomly selected to reflect demographic and disease characteristics of the DISCOVER-2 population) comprised inflammatory ( N = 100) and collagen ( N = 178) biomarker cohorts. Methods: Pharmacodynamic effects of guselkumab through 2 years on inflammatory and collagen biomarker levels (general linear model) and associations between biomarkers and improvements in composite measures of joint, skin, and overall disease activity (Spearman linear regression) through 2 years were assessed. …”
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4516
HE4 as a Prognostic Biomarker of Major Adverse Cardiovascular Events in Patients with Abdominal Aortic Aneurysm: A Canadian Prospective Observational Study
Published 2025-06-01“…<b>Background:</b> Abdominal aortic aneurysm (AAA) is a chronic inflammatory disease characterized by the proteolytic breakdown of the extracellular matrix. …”
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4517
The predictive value of the serum creatinine-to-albumin ratio (sCAR) and lactate dehydrogenase-to-albumin ratio (LAR) in sepsis-related persistent severe acute kidney injury
Published 2025-01-01“…Abstract Background/objectives Sepsis-related acute kidney injury (SA-AKI) is a severe condition characterized by high mortality rates. …”
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4518
Remnant cholesterol inflammatory index, calculated from residual cholesterol to C-reactive protein ratio, and stroke outcomes: a retrospective study using the National institutes o...
Published 2025-07-01“…Abstract Background Globally, acute ischemic stroke (AIS) persists as a significant driver of both mortality and prolonged disability. …”
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4519
Infections and antibiotic resistance in Malawian children 6-59 months old hospitalized with severe acute malnutrition
Published 2025-03-01“…Background: Severe acute malnutrition (SAM) is strongly associated with mortality in young children, and infections are thought to be a major driver of that mortality. …”
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4520
Profiling of gastric cancer cell-surface markers to achieve tumour–normal discrimination
Published 2020-12-01“…However, a systematic analysis of cell-surface markers and development of a composite panel involving multiple candidates to differentiate tumour from normal has not been previously reported.Methods Whole transcriptome sequencing (WTS) of GC and matched normal samples from the Singapore Gastric Cancer Consortium (SGCC) was used as a discovery cohort to identify upregulated putative cell-surface proteins. …”
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