Global landscape and trends in lifetime risks of haematologic malignancies in 185 countries: population-based estimates from GLOBOCAN 2022Research in context by Kexin Sun, Hongliang Wu, Qian Zhu, Kai Gu, Hui Wei, Shaoming Wang, Li Li, Chunxiao Wu, Ru Chen, Yi Pang, Bingfeng Han, Hongmei Zeng, Meicen Liu, Rongshou Zheng, Wenqiang Wei

“…Summary: Background: Haematologic malignancies accounted for 6.6% of total cancer cases and 7.2% of total cancer-related deaths worldwide in 2022. …”
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The effect of intrawound vancomycin powder on surgical site infection in inguinal lymph node dissection: a randomized controlled trial pilot study by Jessica B. DiSilvestro, Emily Zitek, Katina Robison, Jasmine Ebott, Corinne Jansen, Katrin Eurich, Cara Mathews, Paul DiSilvestro, Matthew Oliver, Ashley Stuckey, Katherine Miller, Elizabeth Lokich

“…Background: Inguinal lymph node dissections are morbid surgeries with high rates of postoperative wound infections. …”
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Effects of Therapeutic Hypothermia and Minimal Enteral Nutrition on Short-Term Outcomes in Neonates with Hypoxic–Ischemic Encephalopathy: A 10-Year Experience from Oman by Manoj Malviya, Sathiya Murthi, Dhanya Jayaraj, Vidya Ramdas, Fadia Nazir Malik, Valsala Nair, Nusrabegam Marikkar, Mukesh Talreja, Tariq Sial, Prakash Manikoth, Renjan Varghese, Khalsa Ali Al Ramadhani, Salima Al Aisry, Said Al Kindi, Ahmed Al Habsi, Ranjit Torgalkar, Munawwar Ahmed, Mohammed Al Yahmadi

“…Here, we report our single-center experience with TH over a 10-year period”. Methods: A total of 187 neonates with moderate to severe HIE who underwent cooling were included in this retrospective study. …”
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Two decades of experience of the Fabry Outcome Survey provides further confirmation of the long-term effectiveness of agalsidase alfa enzyme replacement therapy by Uma Ramaswami, Guillem Pintos-Morell, Christoph Kampmann, Kathleen Nicholls, Dau-Ming Niu, Ricardo Reisin, Michael L. West, Christina Anagnostopoulou, Jaco Botha, Dalia Jazukeviciene, Jörn Schenk, Derralynn A. Hughes, Roberto Giugliani

“…Methods: The impact of agalsidase alfa treatment on renal, cardiac, morbidity, and mortality outcomes in FOS was compared with untreated external Fabry disease (FD) cohorts. …”
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High‐Normal Serum Potassium, Calcium, and Magnesium Levels Are Associated With Decreased Risks of Adverse Outcomes After Ischemic Stroke by Quan Yu, Yang Liu, Xinyue Chang, Xueyu Mao, Xuechun Wu, Min Chu, Huicong Niu, Mengyao Shi, Lulu Sun, Yu He, Yi Liu, Daoxia Guo, Zhengbao Zhu, Jing Zhao

“…Background High serum potassium, calcium, and magnesium levels have been reported to be associated with decreased risks of ischemic stroke, whereas their prognostic values in ischemic stroke remain unclear. …”
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A biomimetic multimodal nanoplatform combining neutrophil-coated two-dimensional metalloporphyrinic framework nanosheet and exendin-4 to treat obesity-related osteoporosis by Qifan Yang, Jing Liu, Yanwei Liu, Shun Liu, Xiaokang Wei, Yilin Yang, Weijie Zhang, Shuqi Zhang, Maosheng Zhang, Bin Liu, Xinyu Wang, Dong Zhu

“…Background: Obesity-induced osteoporosis is a prevalent complication among obese individuals. …”
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TreatmENT of AnastomotiC LeakagE after colon cancer resection: the TENTACLE – Colon study by Jobbe M. G. Lemmens, Sander Ubels, Nynke G. Greijdanus, Kiedo Wienholts, Marleen M. H. J. van Gelder, Albert Wolthuis, Jérémie H. Lefevre, Kilian Brown, Matteo Frasson, Nicolas Rotholtz, Quentin Denost, Rodrigo O. Perez, Tsuyoshi Konishi, Martin Rutegård, Susan L. Gearhart, Thomas Pinkney, Muhammed Elhadi, Roel Hompes, Pieter J. Tanis, Johannes H. W. de Wilt

“…Abstract Background Anastomotic leakage (AL) is a common and severe complication after colon cancer resection, but studies investigating various treatment strategies and factors influencing outcomes are scarce. …”
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Healthy lifestyle factors and combined macrovascular and microvascular events in diabetes patients with high cardiovascular risk: results from ADVANCE by Shoujiang You, Danni Zheng, Yanan Wang, Qiang Li, Tu N. Nguyen, Ruth Peters, Xiaoying Chen, Xia Wang, Yongjun Cao, Diederick E. Grobbee, Stephen Harrap, Giuseppe Mancia, Bryan Williams, Neil R. Poulter, Liu Lisheng, Michel Marre, Pavel Hamet, Craig S. Anderson, Mark Woodward, John Chalmers, Katie Harris

“…Abstract Background To explore whether healthy lifestyle factors (HLFs) predict a lower risk of major macrovascular and microvascular events and death in people with type 2 diabetes (T2D) with a high risk of vascular complications. …”
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Histological validation of three-dimensional variable flip angle turbo spin echo multi-contrast magnetic resonance vessel wall imaging in characterizing carotid vulnerable atherosc... by Jiachen Liu, Zihan Ning, Chenlin Du, Shuo Chen, Tao Wang, Jingli Cao, Ran Huo, Dongye Li, Dandan Yang, Rui Shen, Shuwan Yu, Chunjiang Hu, Shuhao Wang, Huiyu Qiao, Xihai Zhao

“…ABSTRACT: Background: Accurate assessment of the vulnerability of carotid atherosclerotic plaques is crucial for stroke prevention. …”
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Assessing the Comparative Efficacy and Safety of Warfarin and Rivaroxaban for Cancer Associated Thrombosis: Experience From a Resource Limited Setting by Abel Tenaw Tasamma, Tsegab Alemayehu Bukate, Abdulrahim Mehadi, Bereket Tagesse Handiso, Beniam Yohannes Kassa, Eman Omer Hassen, Zekarias Seifu Ayalew, Dawit Habtie Tegegne, Gebeyehu Tessema Azibte, Tigest Abebaw Zewdie, Tinsaye Zergaw Shihur, Yonas Degelo Geremamo, Yeabsira Dessalegne Mesfin, Rediet M. Alemayehu, Amanuel Kassu Asefa, Fozia Abdela, Addisu Melkie

“…ABSTRACT Background Thromboembolic events are a common cause of morbidity and mortality in patients with cancer. …”
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Carbohydrate antigen-125 (CA125): a marker of right ventricular dysfunction and poor prognosis in heart failure with preserved ejection fraction by Sher May Ng, Geert H.D. Voordes, Michelle Lobeek, Michiel Rienstra, Adriaan A. Voors, Elke S. Hoendermis, Dirk J. van Veldhuisen, Thomas M. Gorter

“…Background: Right ventricular (RV) dysfunction (RVD) in heart failure (HF) with preserved ejection fraction (HFpEF) is recognised late and associated with poor outcomes. …”
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Cancer history and mortality risk in acute myocardial infarction: Insights from the Japan AMI registry by Ayumi Adachi, Kazuma Oyama, Jun Takahashi, Satoshi Honda, Kensaku Nishihira, Sunao Kojima, Misa Takegami, Yasuhide Asaumi, Jun Yamashita, Mike Saji, Kiyoshi Hibi, Yasuhiko Sakata, Morimasa Takayama, Tetsuya Sumiyoshi, Hisao Ogawa, Kazuo Kimura, Satoshi Yasuda

“…Background: The association between a history of cancer and clinical outcomes in patients with acute myocardial infarction (AMI) remains unclear. …”
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Combination of Left Ventricular End-Diastolic Diameter and QRS Duration Strongly Predicts Good Response to and Prognosis of Cardiac Resynchronization Therapy by Zhinian Guo, Xiaoyan Liu, Xiaofeng Cheng, Chuan Liu, Ping Li, Yongming He, Rongsheng Rao, Chun Li, Yunlong Chen, Yong Zhang, Xiaoyu Luo, Jiang Wang

“…Background. Approximately 20–40% of recipients of cardiac resynchronization therapy (CRT) do not respond to it based on the current patient selection criteria. …”
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Long-Term Nonprogression Is a Form of Response to Cardiac Resynchronization Therapy by Sander Trenson, MD, PhD, Peter C. Kahr, MD, Bert Vandenberk, MD, PhD, Matthias Schindler, PhD, Alexander Breitenstein, MD, Ardan M. Saguner, MD, Andreas J. Flammer, MD, Frank Ruschitzka, MD, Firat Duru, MD, Jan Steffel, MD, Stephan H. Winnik, MD, PhD

“…Background: Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in selected heart failure patients. …”
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Immune profiling of the macroenvironment in colorectal cancer unveils systemic dysfunction and plasticity of immune cells by Haoxian Ke, Peisi Li, Zhihao Li, Xian Zeng, Chi Zhang, Shuzhen Luo, Xiaofang Chen, Xinlan Zhou, Shichen Dong, Shaopeng Chen, Junfeng Huang, Ming Yuan, Runfeng Yu, Shubiao Ye, Tuo Hu, Zhonghui Tang, Dongbin Liu, Kui Wu, Xianrui Wu, Ping Lan

“…Abstract Background Tumour immune macroenvironment is comprised of tumour and surrounding organs responding to tumourigenesis and immunotherapy. …”
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Prognostic impact of changes in left ventricular ejection fraction and wall motion score index in patients with myocardial infarction by Min-Wook Bae, Seong-guen Moon, Kyung-Tae Jung, Won-Ho Kim, Sang-Hyun Park, Jihun Ahn, Jin-Yong Hwang, Seok Kyu Oh, Seung Ho Hur, Myung Ho Jung, Kyu-Sun Lee

“…BackgroundThe prognostic significance of changes in left ventricular ejection fraction (LVEF) and wall motion score index (WMSI) in patients with myocardial infarction remains unclear.MethodsThis study evaluated whether changes in LVEF and WMSI can predict clinical outcomes and LV remodeling in post-AMI patients. …”
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Associations between Multiple Food Consumption Frequencies and the Incidence of Cardiovascular Disease in High Cardiac Risk Subjects by Xiaohui Xu, Shiyun Hu, Sijie Shen, Fang Ding, Jianlin Shao, Xiafen Shen, Tianxu Chen, Xiaoling Xu, Jing Yan, Yin Zhu, Qiang Cai, Wei Yu

“…Methods: We comprehensively assessed the relationship between food consumption frequencies and CVD in 28,979 high-risk subjects. …”
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Right Ventricular Function Score by Echocardiography for Predicting Outcomes After Heart Transplantation by Wei Sun, Yuji Xie, Ye Zhu, Yun Yang, Xin Zhang, Nianguo Dong, Guohua Wang, Yuman Li, Jing Wang, Qing Lv, Mingxing Xie, Li Zhang

“…Background The impaired right ventricular (RV) function may occur after heart transplantation (HT). …”
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Maternal exposure to air pollution and the risk of small for gestational age in offspring: A population-based study in Taiwan by Chien-Yu Huang, Chia-Lin Liu, Mei-Huei Chen, Po-Nien Tsao, Chien-Yi Chen, Hung-Chieh Chou, Pau-Chung Chen

“…Background: Exposure to air pollution has been associated with a wide range of adverse health effects; however, few studies addressed the relationship between ambient particulate matter as well as the compositions in particulate matter such as lead and the risk of small for gestational age (SGA) in offspring. …”
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Chronic cOronary Syndrome in Swedish PRImary care (COSPRI)—a study protocol for a 5-year cluster randomized controlled trial on a novel package versus standard investigation in pat... by Staffan Nilsson, Fade Gabro, Erik Stertman, Lars Bernfort, Mats Fredrikson, Pontus Henriksson, Peter Johansson, Lisa Kastbom, Anita Kärner Köhler, Johan Lööf, Ghassan Mourad, Eva Olsson, Carlos Valladares, Carl Johan Östgren, Sofia Sederholm Lawesson, Jan Engvall, Fredrik Iredahl

“…The standard investigation is comprised of exercise bicycle stress testing and echocardiography. Methods The trial involves patients with a pre-test probability > 15% for significant CAD referred from primary healthcare centers (PHCs) in Region Östergötland (population 471,241 in March 2023) in south-east Sweden. …”
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