A multicenter retrospective study on comparing the efficacy and safety of the therapy of intermittent cyclophosphamide and corticosteroids versus rituximab for primary membranous n... by Yi Wang, Xiaoyan Ma, Xinyu Yang, Shoujun Bai, Xiujuan Zang, Lin Liao, Yakun Wang, Zexin Lv, Ting Zhang, Shougang Zhuang, Na Liu

“…Background Few clinical studies compare the long-term remission, relapse, and safety of rituximab (RTX) or a combination of intermittent intravenous infusion of cyclophosphamide (CTX) and oral corticosteroid for primary membranous nephropathy (PMN) patients.Methods We collected multicenter retrospective data on PMN patients with nephrotic syndrome who received RTX or intermittent intravenous CTX with oral corticosteroids between 1 January 2019 and 31 January 2024. …”
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A peek into hospital poo: Tracking pathogens and antimicrobial resistance by Reshma Silvester, William B Perry, Gordon Webster, Laura Rushton, Amy Baldwin, Daniel A Pass, Neil Byrnes, Peter Kille, Kata Farkas, Barbara Kasprzyk Hordern, Andrew J Weightman, Gareth Jones, Davey L Jones

“…Tracking the type and load of AMR and pathogens within hospital environments is crucial for informing policy decisions and implementing effective risk mitigation strategies METHODS: Twenty-hour composite waste-water samples were collected from hospital outfall pipes using refrigerated autosamplers. …”
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Consequences, costs and cost-effectiveness of workforce configurations in English acute hospitals by Peter Griffiths, Christina Saville, Jane Ball, David Culliford, Jeremy Jones, Francesca Lambert, Paul Meredith, Bruna Rubbo, Lesley Turner, Chiara Dall’Ora

“…Background The National Health Service faces significant challenges in recruiting and retaining registered nurses. …”
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Effect of Self-reported Physical Activity on Glycaemia and Blood Pressure in Healthy Participants from Bissau: A Cross-sectional Study by Lilica Sanca, Cipriano Có, Nelson Namara, Aladje Lopes, Albino Emanuel, Bárbara Oliveiros, Stine Byberg, Morten Bjerregaard-Andersen, Eugénia Carvalho, Alain Massart, Ana Teixeira

“…Abstract Background Recent data show a dramatic increase in non-communicable diseases in developing countries, including cardiovascular disease, obesity and diabetes. …”
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Physiological measures variability and risks of heart disease and stroke: evidence from three cohort studies by Wei Liu, Lieyang Fan, Da Shi, Linling Yu, Jiahao Song, Ruyi Liang, Xuefeng Lai, Hao Wang, Yongfang Zhang, Shuhui Wan, Yueru Yang, Bin Wang

“…Methods We constructed a composite score (0 ~ 3) of variability in physiological measures, including blood pressure, pulse rate, and body mass index, in older adults from the China Health and Retirement Longitudinal Study (CHARLS) 2011 ~ 2015, the Health and Retirement Study (HRS) 2006/2008 ~ 2014/2016, and the UK Biobank 2006 ~ 2019. …”
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Vision-related Quality of Life (VRQOL) and its determinants among the Elderly in rural blocks of Haryana, India by Mona Duggal, Ankita Kankaria, Latika Rohilla, Harashish Jindal, Limalemla Jamir, Parul Chawla Gupta, Debarati Sarkar, Vaibhav Miglani, Akash Kumar, Drishti Sharma, Neha Dahiya, Siddhartha Sharma, Sandeep Grover

“…Background: Vision related quality of life (VRQOL) measures one's satisfaction with their visual ability to perform daily activities. …”
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Oxidative balance score and mortality: mediating role of insulin resistance across age strata in the NHANES cohort by Lin Zhang, Lin Zhang, Heming Zhang, Heming Zhang, Hongxia Xiang, Jiachen Zhang, Wei Gong, Junjie Xv, Xue Yu

“…BackgroundThis study examined the association between oxidative balance score (OBS), a composite measure of oxidative/antioxidative factors, and mortality, while investigating insulin resistance (IR) indices as potential mediators using a nationally representative cohort.MethodsA cohort of 11,849 U. …”
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Dermal Substitute Integra for the Treatment of Mammalian Bite Injuries of Nose: a New Reconstructive Ladder by Ilaria Mataro, MD, Santolo D’Antonio, MD, Matteo D’Alessio, MD, Carlo Petroccione, MD, Dario D’Angelo, MD, Simone La Padula, MD, Roberto D’Alessio, MD, Stefano Avvedimento, MD

“…Background:. Bite injuries affecting the nose are uncommon occurrences characterized by their intricate nature and potential for severe complications. …”
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Volatile Compounds in Musk and Their Anti-Stroke Mechanisms by Chengli Zheng, Xin Shi, Qinling Yang, Zhongkun Cai, Xiao Wang, Liuqing Yang, Xue Bai, Xiuxiang Meng, Diyan Li, Hang Jie

“…<b>Background/Objectives:</b> Musk is a widely used traditional Chinese medicine derived from musk deer that has the pharmacological effects of “activating blood dredging collateral” and “consciousness-restoring resuscitation”. …”
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Long-term prognostic value of CRP–albumin–lymphocyte index in elderly patients with heart failure with preserved ejection fraction by Qingwei He, Yukun Cao, Xingman Fan, Bowen Li, Qiongyi He, Haitao Zhang

“…Methods: This retrospective study included 320 elderly patients hospitalized at the Air Force Medical Center from October 2016 to April 2019 due to HFpEF. …”
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Safety and efficacy of sirolimus combined with cyclosporine in primary membranous nephropathy: a randomized controlled trial by Fang Wang, Chao Yang, Yue Shu, Cai-xia Lin, Yao Yao, Yue Li, Yi-miao Zhang, Xin Wang, Li-qiang Meng, Xu-yang Cheng, Gang Liu, Ming-hui Zhao, Zhao Cui

“…Abstract Background Calcineurin inhibitors, such as cyclosporine, are primary treatments for membranous nephropathy (MN). …”
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Framing of Oil Spillage and Gas Flaring in Rivers State in Three Selected Nigerian Newspapers by Ata-Awaji Reuben, Nyerhovwo MUOBOGHARE, Bassey IKOT-OSIN, Soibi ORUWARI, Etimbuk OBOT, Emmanuel Omula, Theresa LINUS, Peace OJONTA, Simon SHEYIGARI

“…Objective: The study aimed at ascertaining how Punch, Vanguard and Daily Trust newspapers framed oil spillage and gas flaring in Rivers State, from January 2022 to December 2023. Methods: The study adopted content analysis as its research design, thus studying 504 editions of the newspapers selected through composite week sampling. …”
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Association between early initiation of anti-herpesvirus therapy and outcomes in herpesvirus encephalitis: A Nationwide Retrospective Propensity Score Analysis in Japan by Satoshi Kutsuna, Hiroyuki Ohbe, Yuya Kimura, Keito Shinmoto, Yuichiro Matsuo, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga

“…Background: Prompt initiation of anti-herpesvirus therapy is critical in managing herpes simplex virus encephalitis (HSE). …”
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Risk of adverse obstetrical and neonatal outcomes in women consuming recreational drugs during pregnancy by Sreemanjari Kandhasamy, Karine Lepigeon, Stéphanie Baggio, Roulet Céline, Michael Ceulemans, Ursula Winterfeld, Stephen P. Jenkinson, Katyuska Francini, Emeline Maisonneuve, Alice Panchaud

“…Abstract Background Previously conducted studies have observed an increased risk of adverse maternal and neonatal outcomes with prenatal exposure to cocaine and opioids. …”
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Sensitive diagnosis of paucibacillary tuberculosis with targeted next-generation sequencing: a molecular diagnostic study by Yu Chen, Lichao Fan, Zhong Ren, Yanhong Yu, Jiao Sun, Miaoran Wang, Chang Liu, Ying Zhang, Shuihua Lu, Xuhui Liu, Zhen Huang

“…Abstract Background Targeted next-generation sequencing (tNGS) enables high-performance tuberculosis (TB) diagnosis and drug resistance prediction directly from clinical samples. …”
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Analysis of micro-shear bond strength of self-etch adhesive systems with dentine: An in vitro study by Vijay Kumar Shakya, Rajeev Kumar Singh, Anjani Kumar Pathak, Balendra Pratap Singh, Anil Chandra, Ramesh Bharti, Rakesh Kumar Yadav

“…Background: Success or failure of a composite restoration largely depends on its bonding to enamel/dentine. …”
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Outcomes of Del Nido and hyperkalemic blood cardioplegia in adult cardiac surgery with prolonged aortic cross-clamp times★ by Szpytma Malgorzata, Gimpel Damian, Ross Jordan, Newland Richard F., Crouch Gareth, Rice Gregory D., Bennetts Jayme S., Baker Robert A.

“…Therefore, this study aimed to assess the safety and efficacy of our DNC strategy by comparing post-operative troponin profiles and clinical outcomes between Del Nido and hyperkalaemic cardioplegia for cases with aortic cross-clamp times of greater than 90 min. Methods: A single-centre, retrospective cohort study at Flinders Medical Centre and Flinders Private Hospital of patients undergoing composite cardiac surgery with a cross-clamp time longer than 90 min. …”
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Outcomes of Combined Left Atrial Appendage Occlusion and Transcatheter Mitral Edge-to-Edge Repair by Abdullah Al-Abcha, MD, Pietro Di Santo, MD, Charanjit S. Rihal, MD, MBA, Trevor Simard, MD, PhD, Benjamin Hibbert, MD, PhD, Mohamad Alkhouli, MD, MBA

“…Background: Up to 50% of patients undergoing mitral transcatheter edge-to-edge repair (MTEER) have an indication for left atrial appendage occlusion (LAAO). …”
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Thiazolidinedione Use and Cardiovascular Outcomes in Patients With Type 2 Diabetes Who Underwent Carotid Artery Revascularization by Jun Hwee Kim, Jimin Jeon, Seok‐Jae Heo, Tae‐Jin Song, Minyoul Baik, Joonsang Yoo, Jinkwon Kim

“…Background Thiazolidinediones are oral antidiabetic agents known for their wide‐ranging pleiotropic effects, potentially offering cardiovascular protection. …”
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Early Real-World Experience with CoreValve Evolut PRO and R Systems for Transcatheter Aortic Valve Replacement by Gaurav Rao, Shikha Sheth, Joseph Donnelly, Andrew Scatola, Umair Tariq, Saaron Laighold, Cindy Grines, Bruce Rutkin

“…Safety and efficacy of this valve have not previously been compared to its predecessor, the Evolut R valve. Methods. We retrospectively studied 134 patients who underwent TAVR with the Evolut PRO or Evolut R valve over one year at a tertiary center. …”
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