Overburden failure characteristics and fracture evolution rule under repeated mining with multiple key strata control by Sun Chaoshang, Shi Chaoyang, Zhu Zhiming, Lin Haixiao, Li Zhenhua, Du Feng, Cao Zhengzheng, Lu Pengtao, Liu Lin

“…Abstract To master the overburden structure failure and fracture evolution law under multi-key stratum control during repeated mining in coal seams, this study takes the superimposed mining faces of 6# and 7# coal seams in Xinjiang mining area as the research background. Through comprehensive research methods including theoretical analysis, similarity simulation, numerical simulation, and field monitoring, it systematically reveals the evolution law of overburden fractures under repeated mining controlled by multiple key strata, and clarifies the crucial control effects of cumulative damage in the overburden and the superimposed effect of mining-induced stress fields on fracture morphology during repeated mining of close-distance coal seams. …”
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Age-related vaginal microecology and infection epidemiology among premenopausal and postmenopausal gynecologic outpatients: a cross-sectional study by Wenyu Lin, Wenyu Lin, Wenyu Lin, Liying Wang, Liying Wang, Liying Wang, Binhua Dong, Binhua Dong, Binhua Dong, Yuhang Zhang, Yan Zhang, Liang Wang, Liang Wang, Jun Shen, Yanfang Lu, Meijin Zheng, Meijin Zheng, Pengming Sun, Pengming Sun, Pengming Sun

“…This cross-sectional study investigates the epidemiology of vaginal infections and alterations in microbiota composition, enzymes, and metabolites among premenopausal and postmenopausal gynecologic outpatients.MethodsThe study analyzed the vaginal microecology data from 27,346 women who underwent examinations at Fujian Maternity and Child Health Hospital between 2018 and 2023. …”
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Loss of FXR or Bile Acid-dependent Inhibition Accelerate Carcinogenesis of Gastroesophageal AdenocarcinomaSummary by Theresa Baumeister, Andrea Proaño-Vasco, Amira Metwaly, Karin Kleigrewe, Alexander Kuznetsov, Linus R. Schömig, Martin Borgmann, Mohammed Khiat, Akanksha Anand, Julia Strangmann, Katrin Böttcher, Dirk Haller, Andreas Dunkel, Veronika Somoza, Sinah Reiter, Chen Meng, Robert Thimme, Roland M. Schmid, Deepa T. Patil, Elke Burgermeister, Yiming Huang, Yiwei Sun, Harris H. Wang, Timothy C. Wang, Julian A. Abrams, Michael Quante

“…Background & Aims: The incidence of Barrett esophagus (BE) and gastroesophageal adenocarcinoma (GEAC) correlates with obesity and a diet rich in fat. …”
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E. Coli cytotoxic necrotizing factor-1 promotes colorectal carcinogenesis by causing oxidative stress, DNA damage and intestinal permeability alteration by Michela Tozzi, Alessia Fiore, Sara Travaglione, Francesca Marcon, Gabriella Rainaldi, Elena Angela Pia Germinario, Ilenia Laterza, Simona Donati, Daniele Macchia, Massimo Spada, Omar Leoni, Maria Cristina Quattrini, Donatella Pietraforte, Sofia Tomasoni, Filippo Torrigiani, Ranieri Verin, Paola Matarrese, Lucrezia Gambardella, Francesca Spadaro, Maria Carollo, Agostina Pietrantoni, Francesca Carlini, Concetta Panebianco, Valerio Pazienza, Filomena Colella, Donatella Lucchetti, Alessandro Sgambato, Antonella Sistigu, Federica Moschella, Marco Guidotti, Olimpia Vincentini, Zaira Maroccia, Mauro Biffoni, Roberta De Angelis, Laura Bracci, Alessia Fabbri

“…Abstract Background Bacterial toxins are emerging as promising hallmarks of colorectal cancer (CRC) pathogenesis. …”
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Gut dysbiosis is associated with difficult-to-treat rheumatoid arthritis by Patricia Ruiz-Limón, Patricia Ruiz-Limón, Patricia Ruiz-Limón, Natalia Mena-Vázquez, Natalia Mena-Vázquez, Isabel Moreno-Indias, Isabel Moreno-Indias, Isabel Moreno-Indias, Jose Manuel Lisbona-Montañez, Jose Manuel Lisbona-Montañez, Jose Manuel Lisbona-Montañez, Arkaitz Mucientes, Arkaitz Mucientes, Sara Manrique-Arija, Sara Manrique-Arija, Sara Manrique-Arija, Rocío Redondo-Rodriguez, Rocío Redondo-Rodriguez, Laura Cano-García, Laura Cano-García, Francisco J. Tinahones, Francisco J. Tinahones, Francisco J. Tinahones, Francisco J. Tinahones, Antonio Fernández-Nebro, Antonio Fernández-Nebro, Antonio Fernández-Nebro

“…Therefore, the aim of this study was to analyze the gut microbiota and inflammation in patients with D2T RA in comparison to patients with easy-to-treat RA (E2T RA).ObjectiveTo analyze the gut microbiota and inflammation in patients with D2T RA.MethodsWe performed an observational study of a prospective cohort between 2007 and 2011 and analyzed the gut microbiota. …”
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Mitigation of chemotherapy-induced gut dysbiosis and diarrhea by supplementation with heat-killed Bacteroides fragilis by Xinwen Yan, Xinlong Lin, Jianhua Wu, Lijun Zheng, Yangyang Liu, Fang Wu, Ying Lin, Yishi Lu, Chongyang Huang, Binhai Shen, Hongbin Liu, Ruo Huang, Fengyi Hou, Qian Zhou, Mengyao Song, Ke Liu, Fangqing Zhu, Sheng Li, Yuqing Lin, Wei Wang, Ping Li, Wangjun Liao, Fachao Zhi

“…Abstract Background The role of gut microbial dysbiosis in chemotherapy-induced diarrhea (CID) pathogenesis remains unclear in humans. …”
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Natural lung-tropic TH9 cells: a sharp weapon for established lung metastases by Tao Chen, Hao Zhou, Shuming Li, Nong Lin, Yixuan Feng, Zhijian Cai, Chenxiao Qiao, Eloy Yinwang, Shengdong Wang, Xuehuan Wen, Xiangang Jin, Yucheng Xue, Wenkan Zhang, Xianchang Zeng, Zenan Wang, Hangxiang Sun, Lifeng Jiang, Hengyuan Li, Binghao Li, Zhaoming Ye

“…Background Lung metastasis remains the primary cause of tumor-related mortality, with limited treatment options and unsatisfactory efficacy. …”
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Application of machine learning in soil heavy metals pollution assessment in the southeastern Tibetan plateau by Yan Li, Yilong Yu, Shiyuan Ding, Wenjing Dai, Rongguang Shi, Gaoyang Cui, Xiaodong Li

“…The BiLISA method revealed significant spatial interactions among HMs, with the composite pollution of As and Cd occupying the largest proportion in High (As)-High (Cd) aggregation zones, underscoring the need for integrated management strategies. …”
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Selective Dissolution of Clay Minerals in Tight Sandstone by Organic Acids by Fei YANG, Zhichao SHEN, Jiangmin DU, Fang WANG, Bo DONG

“…As important factors affecting reservoir exploration and development, their organic acid dissolution effects on clay minerals need to be further studied.OBJECTIVES(1) In order to explore the main influencing factors of organic acids on the dissolution of clay minerals in tight sandstone, by analyzing the influence of time, temperature and different types of organic acids on the dissolution of clay minerals. (2) To reveal the dissolution reaction mechanism between organic acid fluids and tight sandstone, providing a theoretical basis for improving the prediction ability of relatively high-quality reservoirs under tight backgrounds.METHODS(1) The Triassic Yanchang Formation in the Ordos Basin was selected as the research object, and the ratio of reaction fluid to sandstone dissolution simulation experiment was conducted according to the type and content of organic acid in the thermal evolution fluid of Source rock. (2) After the reaction, the column rock sample was rinsed multiple times with distilled water, placed in a drying oven, dried for 24h, and then taken out for testing. …”
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Direklo-Mehdikhan Alkaline Basalt District, an Indication of a Quaternary Continental Within Plate Extensional Mechanism by Fatemeh Narimani, MohammadAli Mackizadeh, Mortaza Sharifi

“…Therefore, this study focuses on the Direklo-Mehdikhan volcanic district.Petrographic observations, along with whole-rock geochemstry and clinopyroxene mineral chemistry, were carried out to enhance our understanding of the magmatic activity of the Direklo-Mehdikhan volcanic district.Research MethodsThe study started by fieldwork, petrographic analysis, and geochemical investigations. …”
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Response of Anti-Oxidative Stress Genes in Liver and Intestine in Broilers Fed Organic Acid and Silver Nanoparticles Coated on Zeolite in Starter Period by Fatemeh Asgharnezhad, Seyed Reza Hashemi, Saeed Hassani, Sharif Rostami

“…Extended Abstract Background: The use of food supplements to improve growth, optimal production and increase feed efficiency in feeding livestock and poultry has become a common thing as a suitable solution in using feed as well as possible. …”
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Understanding patient pathways to Mother and Baby Units: a longitudinal retrospective service evaluation in the UK by Nikolina Jovanović, Žan Lep, Giles Berrisford, Aysegul Dirik, Julia Barber, Bukola Kelani, Olivia Protti

“…Background Mother and Baby Units are specialised psychiatric facilities for women during and after pregnancy. …”
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Application of Microgravity Experiments in Plastic Surgery: A Literature Review by Jonathan Cornacchini, MD, Yanis Berkane, MD, PhD, Vlad Tereshenko, MD, PhD, Olivier Camuzard, MD, PhD, Alexandre G. Lellouch, MD, PhD, Elise Lupon, MD, PhD

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Systematic review on the application of 3D‐bioprinting technology in orthoregeneration: current achievements and open challenges by Rachel L. Pan, Kari Martyniak, Makan Karimzadeh, David G. Gelikman, Jonathan DeVries, Kelly Sutter, Melanie Coathup, Mehdi Razavi, Rajendra Sawh‐Martinez, Thomas J. Kean

“…Methods This review was performed using PubMed and Web of Science. …”
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Color Masking of Two Types of Medium Translucency Lithium Disilicate Ceramic Restorations by Spectrophotometry by T Rostamzadeh, S Alipour, F Golsorkhtabar

“…The aim of this study was to determine the color coverage of two types of medium translucency lithium disilicate (LDS) ceramic restorations by spectrophotometry. Methods: In this in-vitro study, 15 A2 colored LDS discs using heat-pressed technique were prepared in two methods: MT monolithic LDS discs (thickness of 1.5 mm) and core-veneer discs (0.9 mm MT veneer and 0.6 mm high opacity core). …”
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Use of Beta-Blockers as a First-Line Treatment for Primary Hypertension by Maryam Izadi, Shiva Shafabakhsh, Amir Mirnateghi

“…Therefore, this study aimed to clarify beta-blocker efficacy by incorporating the data from all relevant beta-blocker trials, using the composite outcome of major cardiovascular events. <i>Method</i>: A search was conducted on MEDLINE, PubMed, Embase, and the Cochrane Library, restricted to published, peer-reviewed, human, meta-analysis, and controlled clinical trials. …”
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The Unignorable Near-ground PM2.5, UFP, PAHs, and BC Levels around a Traffic Prohibited Night Market by Sheng-Lun Lin, Hongjie Zhang, Ming-Yeng Lin, Shih-Wei Huang

“…In our study, the night market in Chiayi City was selected as the research object and collected the 24-hour PM2.5 samples through the federal reference method (FRM), characterizing the mass concentration, water-soluble ionic components, carbon specious, metal compositions and source contributions of PM2.5. …”
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Deconstructing the Alcohol Harm Paradox: A Population Based Survey of Adults in England. by Emma Beard, Jamie Brown, Robert West, Colin Angus, Alan Brennan, John Holmes, Eileen Kaner, Petra Meier, Susan Michie

“…<h4>Background</h4>The Alcohol Harm Paradox refers to observations that lower socioeconomic status (SES) groups consume less alcohol but experience more alcohol-related problems. …”
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Novel Pathogenicity of Secretory Proteins from Acinetobacter Radioresistens in Experimental Models by Yuki Suzuki, Toshifumi Osaka, Hidehiro Ueshiba, Naoko Yanagisawa, Satoru Nagata

“…This study investigated the pathogenicity of proteins released extracellularly by Acinetobacter radioresistens (A. radioresistens), isolated from the small intestine of two patients with severe Kawasaki disease, in a mouse model. Methods: The sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis of culture supernatants derived from Acinetobacter species showed large variations in protein compositions among species and strains. …”
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Expert consensus on the technical specifications of the in vitro skin penetration test of cosmetic product by Franz diffusion cell by Bingwen Liang, Liling Zhou, Chuanbin Wu, Liang Fang, Lisheng Wang, Lihua Peng, Peng Shu, Lifeng Tang, Yu Bei, Xiaodong Cui, Xiaojia Chen, Yuan Gao, Chong Han, Yan Jia, Huaqing Lin, Yifang Li, Ying Liu, Yiguang Li, Zhiwei Li, Zixiu Liu, Shaohua Ren, Jun Shi, Wanyang Sun, Lijuan Tian, Qun Wang, Yuan Wang, Yuehong Xu, Ming Zeng, Quangang Zhu, Shu Zhang, Yifan Zhang, Qi Xiang

“…Background: Diffusion cell test is one of the most commonly used in vitro model to detect the percutaneous absorption of cosmetic ingredients. …”
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