The Effect of Initial Orthodontic Therapy with Clear Aligners and Fixed Appliances on Microbial Profiles and Clinical Parameters by Megan Haug, Andrew Hopkins, Emily Duong, Kim-Sa Kelly, Julia Esfandi, Bhumika Shokeen, Tingxi Wu, Renate Lux

“…Background Orthodontic appliances hinder proper oral hygiene, leading to plaque retention and biofilm formation which can cause dental diseases. …”
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Single-cell spatial transcriptomics unravels cell states and ecosystems associated with clinical response to immunotherapy by Sjoerd H van der Burg, Ziena Abdulrahman, Mariette I E van Poelgeest, Roderick C Slieker, Marij J P Welters, Daniel McGuire

“…Background The tumor microenvironment (TME) is a complex and dynamic ecosystem that is known to influence responses to immunotherapy. …”
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Integrating traditional omics and machine learning approaches to identify microbial biomarkers and therapeutic targets in pediatric inflammatory bowel disease by Lanlan Li, XuZai Deng, Shuge Wang, Tao Huang

“…An independent cohort of 36 pediatric stool samples assessed by 16S rRNA sequencing validated top ML results.ResultsTraditional abundance-based methods showed compositional shifts but identified few consistently significant taxa. …”
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Virulence diversity of the yellow rust pathogen population in Dagestan by E. I. Gultyaeva, E. L. Shaydayuk, R. E. Smirnova, K. M. Abdullaev, K. U. Kurkiev

“…Background. Yellow rust incidence on Triticum L. has been observed to surge up in Dagestan in recent years, facilitating selection of highly resistant genotypes. …”
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Genomic structural equation modeling elucidates the shared genetic architecture of allergic disorders by Jingsheng Ruan, Xinglin Yi

“…Methods Our study employed genomic structural equation modeling (Genomic SEM) to define the common factor representing the shared genetic architecture of allergic disorders. …”
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The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio as a predictor of all cause and cardiovascular mortality in United States adults with NAF... by Lisha Yang, Jingwen Li, Yilian Xie, Guoqing Qian

“…Abstract Background The non-HDL cholesterol to HDL cholesterol ratio (NHHR) is a novel composite lipid index. …”
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Mediation Analysis of Serum Fibroblast Growth Factor 20 and Poor Prognosis After Ischemic Stroke by Keyang Chen, Wenting Huang, Beilei Hu, Fangwang Fu, Yungang Cao, Huiqin Xu, Lixin Ruan, Yongang Li, Yan Li, Jun Chen, Fei Liang, Xue Wang, Xudong Du, Li Lin, Xiaokun Li

“…FGF20 levels were measured using the ELISA method. The primary outcome was poor stroke functional outcome (modified Rankin Scale score of 3–6), and secondary outcomes included death and composite vascular events. …”
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Targeting the activated microenvironment with endosialin (CD248)-directed CAR-T cells ablates perivascular cells to impair tumor growth and metastasis by Sarah L Ash, Rebecca Orha, Holly Mole, Meg Dinesh-Kumar, Steven P Lee, Frances K Turrell, Clare M Isacke

“…Background Targeting of solid cancers with chimeric antigen receptor (CAR)-T cells is limited by the lack of suitable tumor-specific antigens and the immunosuppressive, desmoplastic tumor microenvironment that impedes CAR-T cell infiltration, activity and persistence. …”
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An Observational Study of the Effect of Diet and Micronutrient Intake on the Association between Depression and Gastrointestinal Symptoms via an Online Survey Tool by Fahim Syed, Deili Sinimeri, Caroline E. Childs, Dennis Golm

“…Background and objectives: Depression is a low mood-based disorder that affects approximately one in six people in the UK. …”
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Effectiveness of horizontal posts to support MOD cavities compared with other restorative approaches in endodontically treated teeth: systematic review with meta-analysis of labora... by Mohammed Ahmed Alghauli, Ahmed Yaseen Alqutaibi, Redhwan Saleh Al-Gabri, Abdulmajeed Abdulaziz Baik, Anas Mazen Mahrous, Arwa Bafail, Samah Saker

“…Horizontal posts in endodontically treated teeth significantly improved fracture resistance compared with untreated MOD cavities and many restorative methods, though they did not match sound teeth. Combining horizontal posts with materials like polyethylene fiber Ribbond or nanohybrid composites achieved fracture resistance comparable to sound teeth, while finite element analyses showed reduced stress concentrations. …”
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Control Indicators for Typical Persistent Organic Pollutants in Lake Sediments by LUO Xi, XIE Xiao-jing, XU Cheng-jian, ZHANG Lu, YAN Dan, TANG Qiang

“…[Methods] A systematic analysis was conducted on the distribution characteristics and ecological risks of three typical pollutants: dioxins, methylmercury, and short-chain chlorinated paraffins (SCCPs). …”
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Mammographic density and ageing: A collaborative pooled analysis of cross-sectional data from 22 countries worldwide. by Anya Burton, Gertraud Maskarinec, Beatriz Perez-Gomez, Celine Vachon, Hui Miao, Martín Lajous, Ruy López-Ridaura, Megan Rice, Ana Pereira, Maria Luisa Garmendia, Rulla M Tamimi, Kimberly Bertrand, Ava Kwong, Giske Ursin, Eunjung Lee, Samera A Qureshi, Huiyan Ma, Sarah Vinnicombe, Sue Moss, Steve Allen, Rose Ndumia, Sudhir Vinayak, Soo-Hwang Teo, Shivaani Mariapun, Farhana Fadzli, Beata Peplonska, Agnieszka Bukowska, Chisato Nagata, Jennifer Stone, John Hopper, Graham Giles, Vahit Ozmen, Mustafa Erkin Aribal, Joachim Schüz, Carla H Van Gils, Johanna O P Wanders, Reza Sirous, Mehri Sirous, John Hipwell, Jisun Kim, Jong Won Lee, Caroline Dickens, Mikael Hartman, Kee-Seng Chia, Christopher Scott, Anna M Chiarelli, Linda Linton, Marina Pollan, Anath Arzee Flugelman, Dorria Salem, Rasha Kamal, Norman Boyd, Isabel Dos-Santos-Silva, Valerie McCormack

“…<h4>Background</h4>Mammographic density (MD) is one of the strongest breast cancer risk factors. …”
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Behavioral determinants of dental and facial esthetic self-perception among an academic population: a cross-sectional study by Ana Cristina Mafla, Mauricio Herrera-López, Juliana Estefanía Salas-Burbano, Camilo Andrés Guerrero-Dávila, Diana Paola Insuasty-Fuertes, Juan Sebastián Bustos-López, Falk Schwendicke

“…Abstract Background Facial attractiveness is a relevant feature in many societies, and self-perceived attraction has been shown to affect a wide range of aspects in human lives, including quality of life. …”
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Ultrasound Evaluation of Therapeutic Response to Tofacitinib and Upadacitinib in Patients with Rheumatoid Arthritis—Real-Life Clinical Data by Vladimira Boyadzhieva, Konstantin Tachkov, Soner Emin, Zhaklin Apostolova, Rumen Stoilov, Guenka Petrova, Nikolay Stoilov

“…<b>Background</b>: In recent years, musculoskeletal ultrasonography (MSUS) has established itself as a reliable method for evaluating disease activity in combination with clinical examination and laboratory tests. …”
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Mucormycosis at pectoralis major myocutaneous flap donor site by A Saraiya Hemant, A Tankshali Rajen

“…Materials and Methods: A 71-year-old patient presented with right-sided buccal mucosal carcinoma involving the mandible. …”
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Dynamic Aerial Small Target Detection Algorithm Based on Compound Zoom Scaling by Jiang Yuan, Zhu Gaofeng, Zhu Fenghua, Xiong Gang

“…Firstly, a more efficient backbone network is introduced, and a composite scaling method is employed to optimize the balance among network depth, width, and image resolution. …”
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Study on the Law and Control Mechanism of Slope Sliding Instability Under Hanging Wall Coal Mining by Junpeng Li, Wencai Wang, Hongbo Yao, Jingjing Yan, Zhenyu Pei

“…The clarification of the relationship between overburden movement, slope deformation damage, instability, sliding, and control is essential for the safe and efficient recovery of resources when using the room and pillar mining method for recovering trapped coal in edge areas. …”
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Development of a Place Attachment Scale for Adolescents (PASA) and determination of its psychometric qualities by Mustafa Yüksel Erdoğdu

“…Abstract Background Place attachment refers to a relationship with cognitive, emotional and behavioral dimensions that develops over time depending on the interaction of individuals with the social and physical environment. …”
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Mucormycosis at pectoralis major myocutaneous flap donor site by Saraiya Hemant, Tankshali Rajen

“…<b> Materials and Methods:</b> A 71-year-old patient presented with right-sided buccal mucosal carcinoma involving the mandible. …”
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To Evaluate and Compare the Microleakage of Chitosan Nano Hydrogel-Incorporated MTA and Glass Ionomer Cements When used as a Retrograde Filling Material by Vinaykumar G. Suryavanshi, Ravi K. Tale, Vivekanand D. Kolvekar, Rashmi Chordiya, P S Amal, B Abijeet

“…Aim: To evaluate and compare microleakage of chitosan nano hydrogel-incorporated mineral trioxide aggregate (MTA) and glass ionomer cement (GIC) when used as a retrograde filling material. Materials and Methods: Sixty single-rooted premolars were decoronated at cemento enamel junction (CEJ), and root canals were prepared and obturated, with the coronal part sealed with a composite. …”
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