Experiences of discrimination are associated with microbiome and transcriptome alterations in the gut by Tien S. Dong, Tien S. Dong, Tien S. Dong, Tien S. Dong, Tien S. Dong, Simer Shera, Kirstin Peters, Gilbert C. Gee, Gilbert C. Gee, Hiram Beltrán-Sánchez, Hiram Beltrán-Sánchez, May C. Wang, Lisa A. Kilpatrick, Lisa A. Kilpatrick, Lisa A. Kilpatrick, Lisa A. Kilpatrick, Xiaobei Zhang, Xiaobei Zhang, Xiaobei Zhang, Xiaobei Zhang, Xiaobei Zhang, Jennifer S. Labus, Jennifer S. Labus, Jennifer S. Labus, Jennifer S. Labus, Jennifer S. Labus, Allison Vaughan, Allison Vaughan, Allison Vaughan, Allison Vaughan, Arpana Church, Arpana Church, Arpana Church, Arpana Church, Arpana Church

“…BackgroundDiscrimination is a recognized psychosocial stressor that has been linked to various negative health outcomes. …”
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Home-Based Intervention Tool for Cardiac Telerehabilitation: Protocol for a Controlled Trial by Francesca Mastorci, Maria Francesca Lodovica Lazzeri, Lamia Ait-Ali, Paolo Marcheschi, Paola Quadrelli, Massimiliano Mariani, Rafik Margaryan, Wanda Pennè, Marco Savino, Giuseppe Prencipe, Alina Sirbu, Paolo Ferragina, Corrado Priami, Alessandro Tommasi, Cesare Zavattari, Pierluigi Festa, Stefano Dalmiani, Alessandro Pingitore

“… BackgroundAmong cardiovascular diseases, adult patients with congenital heart disease represent a population that has been continuously increasing, which is mainly due to improvement of the pathophysiological framing, including the development of surgical and reanimation techniques. …”
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Full-length 16S rRNA Sequencing Reveals Gut Microbiome Signatures Predictive of MASLD in children with obesity by Yu-Cheng Lin, Chi-Chien Wu, Yun-Er Li, Chun-Liang Chen, Chia-Ray Lin, Yen-Hsuan Ni

“…While recent advancements in full-length 16S (FL16S) rRNA sequencing offer better taxonomic resolution, whether they establish stronger associations with the risk of MASLD remains to be determined. Method This study utilized long-read FL16S and short-read V3-V4 16S rRNA sequencing to profile gut microbiome compositions in age-, sex-, and BMI-matched case–control pairs of obese children with and without MASLD. …”
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Fracture activation in the overburden and aquiclude stability under the mining of close-distance coal seams by Jian CAO, Haitao SU, Chao WANG, Jianwei LI, Liang LI, Xuwei MAO

“…BackgroundIn the Jurassic coalfield of northern Shaanxi Province, the repeated mining of close-distance coal seams exacerbates the activation of fractures in the overburden. …”
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Inequity in access to medications among communities in Eastern Ethiopia: a decomposition analysis by Dumessa Edessa, Fekede Asefa Kumsa, Girmaye Dinsa, Lemessa Oljira

“…Inequity was identified using a concentration index ranked by this composite indicator. Finally, we used RIF’s regression decomposition method to identify the significant contributors to the inequity. …”
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A systematic multimodal assessment of AI machine translation tools for enhancing access to critical care education internationally by Christine L. Chen, Yue Dong, Claudia Castillo-Zambrano, Hassan Bencheqroun, Amelia Barwise, Adria Hoffman, Keivan Nalaie, Yishu Qiu, Oualid Boulekbache, Alexander S. Niven

“…Abstract Background Language barriers pose a significant barrier to expanding access to critical care education worldwide. …”
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Assessing the risk of low energy availability, bone mineral density and psychological strain in endurance athletes by Charlotte R. Gowers, Christopher J. McManus, Henry C. Chung, Ben Jones, Jamie Tallent, Sally P. Waterworth

“…Background Adequate energy intake is crucial for athletic performance and recovery. …”
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Treatment of Alar Deformity After Cosmetic Surgery by Norihiro Ohba, MD, Goichi Haraoka, MD, Mayuko Ohba, MD, Norio Takahashi, MD

“…Methods:. Auricular cartilage grafting was used as the main technique to improve alar flattening and notching without risking a poor color match as is seen in composite grafting. …”
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Single cell RNA-sequencing identified CCR7+/RELB+/IRF1+ T cell responding for juvenile idiopathic arthritis pathogenesis by Lewei He, Xue Gong, Hui Guo, Kaiyu Zhou, Yue Lan, Mingyi Lv, Xiaoliang Liu, Sha Lin, Yimin Hua, Junling Guo, Zhenxin Fan, Yifei Li

“…BackgroundTo further explore the disease heterogeneity of different subtypes of Juvenile idiopathic arthritis (JIA) and analyze their pathogenesis mechanisms.MethodThe single-cell RNA sequencing (scRNA-seq) analysis of peripheral blood mononuclear cells (PBMCs) was carried out to investigate the disease heterogeneity and molecular mechanisms of immune responses in immune cells in JIA.ResultIn our study, we provided a immunological landscape of HLA-B27-positive JIA and HLA-B27-negative JIA immune cells at single cell RNA-Seq resolution. …”
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Effectiveness of physician-based diagnosis versus diagnostic artificial intelligence algorithms in detecting communicable febrile diseases in Mexico by Enrique Alonso Medina Fuentes, Carmen Alicia Ruíz Valdez, Porfirio Felipe Hernández Bautista, David Alejandro Cabrera Gaytán, Guadalupe Minerva Olivas Fabela, José Alberto Mireles Garza, Olga María Alejo Martínez, Brenda Leticia Rocha Reyes, Alfonso Vallejos Parás, Lumumba Arriaga Nieto, Yadira Pérez Andrade, Leticia Jaimes Betancourt, Gabriel Valle Alvarado, Oscar Cruz Orozco, Mónica Grisel Rivera Mahey

“…Background Digital medicine is an important tool in the current healthcare landscape. …”
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3D Hollow MoS2 Architecture Enabled Highly Sensitive SERS Detection by Chao Gao, Yi Yang, Huijie Chen, Xiaoqing Gao, Xingxing Zhang, Zhiqian Song, Tianyang Zhang, Kai Chen, Xiaohong Wang, Yingdong Han

“…The work provides a novel method to enhance the SERS performance of 2D materials, which is readily achievable and is expected to become a key cornerstone for the development of composite substrates.…”
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Advances in the study of exosomes in cardiovascular diseases by Zhaobo Zhang, Yuanming Zou, Chunyu Song, Kexin Cao, Kexin Cai, Shuxian Chen, Yanjiao Wu, Danxi Geng, Guozhe Sun, Naijin Zhang, Xingang Zhang, Yixiao Zhang, Yingxian Sun, Ying Zhang

“…Background: Cardiovascular disease (CVD) has been the leading cause of death worldwide for many years. …”
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Gut mycobiome and neuropsychiatric disorders: insights and therapeutic potential by Ines Hadrich, Mariem Turki, Mariem Turki, Imen Chaari, Imen Chaari, Balkiss Abdelmoula, Rahma Gargouri, Nahed Khemakhem, Dhawia Elatoui, Fatma Abid, Sonda Kammoun, Sonda Kammoun, Mona Rekik, Mona Rekik, Samir Aloulou, Samir Aloulou, Mariem Sehli, Mariem Sehli, Aymen Ben Mrad, Aymen Ben Mrad, Sourour Neji, Fabian M. Feiguin, Jihene Aloulou, Jihene Aloulou, Nouha Bouayed Abdelmoula, Hayet Sellami, Hayet Sellami

“…While bacteria have traditionally been the focus of gut microbiome studies, recent evidence suggests that fungal communities (mycobiota) may also play a crucial role in modulating health, particularly in neuropsychiatric disorders.ObjectiveThis review aims to provide a comprehensive overview of current knowledge on the relationship between the gut mycobiome and neuropsychiatric disorders, exploring the potential of targeting fungal communities as a novel therapeutic strategy.MethodsWe summarized recent findings from metagenomic analyses that characterize the diversity and composition of gut mycobiota and discuss how these communities interact with the host and other microorganisms via the gut-brain axis. …”
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Handgrip strength and menopause are associated with cardiovascular risk in women with obesity: a cross-sectional study by Jaqueline de Paula Chaves Freitas, Joyce Noelly Vitor Santos, Daniela Barreto de Moraes, Gabriele Teixeira Gonçalves, Leonardo Augusto da Costa Teixeira, Maria Thereza Otoni Figueiró, Tamara Cunha, Vanessa Kelly da Silva Lage, Ana Lúcia Danielewicz, Pedro Henrique Scheidt Figueiredo, Henrique Silveira Costa, Alessandro Sartorio, Thyago José Silva, Fidelis Antônio da Silva Júnior, Cheyenne Alves Fonseca, Elizabethe Adriana Esteves, Ana Cristina Rodrigues Lacerda, Vanessa Amaral Mendonça

“…Objectives To investigate the association between the Handgrip Strength (HGS) test and CVR in women with obesity, as well as to evaluate the predictive value of the HGS test as a CVR screening tool in this population. Methods Fifty-five eligible women with obesity, aged 40 to 65 years, were studied. …”
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Gut microbiome and metabolome interactions in Crohn’s disease: mechanistic insights into exclusive enteral nutrition-induced remission by Weiwei Zheng, Weiwei Zheng, Weiwei Zheng, Weiwei Zheng, Quan Zhou, Quan Zhou, Mengli Xue, Mengli Xue, Mengli Xue, Mengli Xue, Xing Yu, Xing Yu, Xing Yu, Xing Yu, Xue’e Chen, Xue’e Chen, Xue’e Chen, Xue’e Chen, Jintong Chen, Jintong Chen, Jintong Chen, Jintong Chen, Chengdang Wang, Chengdang Wang, Chengdang Wang, Chengdang Wang

“…BackgroundExclusive enteral nutrition (EEN) is a first-line therapeutic approach for inducing remission in Crohn’s disease. …”
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Characterization of the complete chloroplast genome and comparative analysis of the phylogeny and codon usage bias of three Yunnan wild rice species by Rongxin Li, Rongxin Li, Rongxin Li, Bo Wang, Bo Wang, Suqin Xiao, Suqin Xiao, Ling Chen, Ling Chen, Fuyou Yin, Fuyou Yin, Jinlu Li, Jinlu Li, Cong Jiang, Cong Jiang, Dunyu Zhang, Dunyu Zhang, Qiaofang Zhong, Qiaofang Zhong, Yun Zhang, Yun Zhang, Jiaxin Xing, Jiaxin Xing, Zaiquan Cheng, Zaiquan Cheng, Li Liu, Li Liu

“…BackgroundWild rice species with a rich genetic diversity, wide adaptability, and high photosynthetic rates provide a valuable genetic reservoir for rice breeding.MethodsIn this study, the chloroplast (cp) genomes of three Yunnan wild rice species, namely Oryza rufipogon, Oryza officinalis, and Oryza granulata, were sequenced using second-generation sequencing technology, followed by assembly and annotation. …”
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Intestinal inflammation and microbiota modulation impact cochlear function: emerging insights in gut-ear axis by Anna Pisani, Valentina Petito, Fabiola Paciello, Valeria Emoli, Letizia Masi, Veronica Mohamed Hizam, Pierluigi Puca, Raffaele Montuoro, Federica Del Chierico, Lorenza Putignani, Claudio Grassi, Jacopo Galli, Maurizio Taglialatela, Maria Emiliana Caristo, Gianluca Ianiro, Loris Riccardo Lopetuso, Giovanni Cammarota, Antonio Gasbarrini, Anna Rita Fetoni, Franco Scaldaferri

“…Methods Here, we investigated the impact of intestinal inflammation and the modulation of gut microbiota through fecal microbiota transplantation on hearing sensitivity. …”
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Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM by Jiaxuan Li, Zhenyu Tian, Tongxue Zhang, Jiajia Jin, Xinjie Zhang, Panpan Xie, Haiyan Lin, Junfei Gu, Yingjie Wu, Xiaowei Wang, Shucui Zhang, Xuefang Yan, Dong Guo, Zhe Wang, Qunye Zhang

“…Abstract Background Vasculopathy underlies diabetic complications, with perivascular adipose tissue (PVAT) playing crucial roles in its development. …”
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Utilizing Freeze-Thaw-Ultrasonication to Prepare Mesoporous Silica-Encapsulated Colloidal Silver Nanoaggregates with Long-Term Surface-Enhanced Raman Spectroscopy Activity by Shuoyang Yan, Ling Chen, Zhiyang Zhang

“…Although the reagent-free “freeze-thaw-ultrasonication” method for preparing Ag nanoaggregates (AgNAs) does not introduce additional background interference and maintains the original interfacial properties of AgNAs, their unstable physical nanostructure limits SERS detection to just 7 days. …”
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Evaluation of the Age Dependence of Conventional and Novel Photoplethysmography Parameters by Flóra Antali, Dániel Kulin, Sándor Kulin, Zsuzsanna Miklós

“…Abstract Background Cardiovascular (CV) mortality increases with age partly due to physiological ageing of the CV system. …”
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