Refining Unfavorable Vaginal Microbial Community in Infertile Women Subjected to Precision Probiotic Intervention: An Exploratory Single-Arm, Prospective, Open-Label, Interventiona... by Giovanna Cocomazzi, Viviana Contu, Silvia De Stefani, Lino Del Pup, Matteo Buccheri, Monica Antinori, Lodovico Parmegiani, Daniele De Ruvo, Francesco Marino, Edy Virgili, Christine Allen, Simone Palini, Walter Ciampaglia, Matteo Cerboneschi, Domenico Baldini, Giorgio Maria Baldini, Valerio Pazienza

“…Background and aims: Vaginal microbiomes have been classified into five different general categories, termed Community State Type (CSTs), with CST-III and CST-IV often associated with vaginal dysbiosis which makes women more prone to recurrent infections and assisted reproductive technology (ART) failure. …”
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Treatment of Vitamin D Deficiency in Decompensated Patients with Cirrhosis Is Associated with Improvement in Frailty by Raquel Díaz-Ruíz, Maria Poca, Eva Román, Berta Cuyàs, Irene Bañares, Ángela Morales, Elvira Hernández Martínez-Esparza, Rocío Panadero, Cristina Velasco, Marta Rapado-Castro, Irene Bretón, Rafael Bañares, German Soriano, Rita García-Martínez

“…<b>Background/aim</b>: Frailty is increasingly recognized as a relevant prognostic factor in patients with cirrhosis, regardless of liver failure. …”
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Efficacy of thunder-fire moxibustion for cancer-related fatigue in breast cancer survivors: study protocol for a randomized controlled trial by Huakang Li, Huakang Li, Zhonglin Zhang, Qiang Li, Yuyang Jin, Yunjing Jia, Pengxuan Gu, Qi Xiao, Lingna Jin, Ziliang Wu, Bing Lin, Shanshan Wei, Jinyi Lang

“…BackgroundCancer-related fatigue (CRF) is one of the most prevalent and debilitating symptoms experienced by breast cancer survivors, often associated with dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. …”
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Gut microbial Nordihydroguaiaretic acid suppresses macrophage pyroptosis to regulate epithelial homeostasis and inflammation by Jun Wang, Huishi Tan, Ziwen Ye, Senhui Weng, Yanqiang Shi, Jiahui Xu, Hongbin Liu, Jierui Li, Linwen Huang, Luyue Zhai, Huishan Luo, Zelong Lin, Cailing Zhong, Jing Tang, Zezheng Wang, Haiyan Zhang, Beiping Zhang, Chongyang Huang

“…Background Aging is associated with increased severity of inflammatory bowel disease (IBD). …”
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Serum and tear autoantibodies from NOD and NOR mice as potential diagnostic indicators of local and systemic inflammation in Sjögren’s disease by Shruti Singh Kakan, Sara Abdelhamid, Sara Abdelhamid, Yaping Ju, Yaping Ju, J. Andrew MacKay, J. Andrew MacKay, J. Andrew MacKay, Maria C. Edman, Indu Raman, Chengsong Zhu, Prithvi Raj, Sarah F. Hamm-Alvarez, Sarah F. Hamm-Alvarez

“…The LG produces the protein-rich aqueous component of tears, and SjD-associated autoimmune dacryoadenitis (AD) may thus alter tear autoantibody composition.MethodsThe presence of tertiary lymphoid structures (TLS) in LG from two murine models of SjD-associated AD, male non-obese diabetic (NOD) and male non-obese insulitis resistant (NOR) mice, were evaluated using immunofluorescence. …”
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Spatial transcriptomics and multi-omics reveal relapse and resistance mechanisms of EndMT-derived CAFs mediated by TNC and FLNC in glioblastoma by Li Ji, Die Xia, Yu Zhou, Yaling Hu, Zhenkun Yang, Ying Yin, Jingjing Wang, Bo Zhang, Lingli Gong, Koukou Li, Jian Zou, Mei Wang

“…Nevertheless, the role and source of CAFs in recurrent and chemotherapy-resistant GBMs still remain ambiguous. Methods Spatial transcriptome (ST) sequencing was conducted on the tissue microarray encompassing primary and recurrent glioma samples in order to characterize the cellular composition. …”
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Assessing the impact of an intensive dietitian-led telehealth intervention focusing on nutritional adequacy, symptom control and optional supplemental jejunal feeding, on quality o... by Emma McShane, Kate Furness, Lauren Hanna, Kate Connell, Terrence Haines, Catherine E. Huggins, John Zalcberg, Sharon Carey, Charles H.C. Pilgrim, Joanne Lundy, Andrew Metz, David Kissane, Michael Franco, John Coutsouvelis, Diederick W. De Boo, J Simon Bell, Mahesh Iddawela, Theresa Dodson, Ignatius Pereira, Nina Imad, Jill Kirkpatrick, Cherie Dear, Daniel Croagh

“…Abstract Background Pancreatic cancer is the third leading cause of cancer-related death in Australia, with a persistently poor 5-year survival rate of around 13%. …”
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Offspring metabolic programming via the maternal diet increases susceptibility to metabolic dysregulationResearch in context by Xuguang Li, Nobuaki Shiraki, Takami Watanabe, Rikako Fukui, Kyohei Furukawa, Yusuke Kato, Yuri Nakahara, Shoen Kume, Akashi Taguchi, Youichiro Wada, Dwina Juliana Warman, Kenji Saito, Haruyo Nakajima-Adachi, Satoshi Hachimura, Hisanori Kato, Huijuan Jia

“…Summary: Background: Maternal nutrition during critical developmental windows is crucial for offspring metabolic programming. …”
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A Data-Driven Approach to Link GC-MS and LC-MS with Sensory Attributes of Chicken Bouillon with Added Yeast-Derived Flavor Products in a Combined Prediction Model by Simon Leygeber, Carmen Diez-Simon, Justus L. Großmann, Anne-Charlotte Dubbelman, Amy C. Harms, Johan A. Westerhuis, Doris M. Jacobs, Peter W. Lindenburg, Margriet M. W. B. Hendriks, Brenda C. H. Ammerlaan, Marco A. van den Berg, Rudi van Doorn, Roland Mumm, Age K. Smilde, Robert D. Hall, Thomas Hankemeier

“…Background: There is a continuous demand to create new, superior sensory food experiences. …”
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Comparative Analysis of Infusions and Ethanolic Extracts of <i>Annona muricata</i> Leaves from Colima, Mexico: Phytochemical Profile and Antioxidant Activity by Gustavo A. Hernandez-Fuentes, Osiris G. Delgado-Enciso, Edgar G. Larios-Cedeño, Juan M. Sánchez-Galindo, Silvia G. Ceballos-Magaña, Kayim Pineda-Urbina, Mario A. Alcalá-Pérez, Nancy E. Magaña-Vergara, Josuel Delgado-Enciso, Uriel Díaz-Llerenas, Janet Diaz-Martinez, Idalia Garza-Veloz, Margarita L. Martinez-Fierro, Iram P. Rodriguez-Sanchez, Ivan Delgado-Enciso

“…Background: <i>Annona muricata</i> L. (guanabana) leaves are rich in bioactive compounds with potential antioxidant properties. …”
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Gradual changes within long-lived influenza virus-specific CD8+ T cells are associated with the loss of public TCR clonotypes in older adultsResearch in context by Carolien E. van de Sandt, Hayley A. McQuilten, Malet Aban, Thi H.O. Nguyen, Sophie A. Valkenburg, Emma J. Grant, Sneha Sant, Jamie Rossjohn, Stephanie Gras, Jane Crowe, Katherine Kedzierska

“…Summary: Background: Susceptibility to life-threatening influenza increases with age, partly due to declining immunity. …”
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Molecular feature-based classification of retroperitoneal liposarcoma: a prospective cohort study by Mengmeng Xiao, Xiangji Li, Fanqin Bu, Shixiang Ma, Xiaohan Yang, Jun Chen, Yu Zhao, Ferdinando Cananzi, Chenghua Luo, Li Min

“…Background: Retroperitoneal liposarcoma (RPLS) is a critical malignant disease with various clinical outcomes. …”
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Indirect Fortification of Traditional Nixtamalized Tortillas with Nixtamalized Corn Flours by María Guadalupe Nieves-Hernandez, Brenda Lizbeth Correa-Piña, Oscar Garcia-Chavero, Salomon Lopez-Ramirez, Rosendo Florez-Mejia, Oscar Yael Barrón-García, Elsa Gutierrez-Cortez, Marcela Gaytán-Martínez, Juana Isela Rojas-Molina, Mario E. Rodriguez-Garcia

“…Methods: The chemical proximate values (CPV), ash content, mineral composition by inductively coupled plasma, in vitro protein digestibility (PD), protein digestibility-corrected amino acid score (PDCAAS), the total starch content, the resistant starch (RS) content in nixtamalized corn tortillas (NC-T) and nixtamalized commercial corn flour tortillas (NCCF-T) and the contribution of tortillas prepared with a mixture of NM and NCC-F (75:25 and 50:50, NM:NCC-F) to the recommended dietary intake (RDI) of minerals and vitamins were determined. …”
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Factors affecting hematological parameters in Creole goats on the Southern Coast of Peru by Jhony Soca, Emmanuel Alexander Sessarego, Pamela Sarmiento, María José Cevallos-Cardenas, Juan Canchino-Gutierrez, Jose Teran, Jose Antonio Ruiz, Juancarlos Cruz-Luis, Danny Julio Cruz

“…Background and Aim: Hematological parameters are critical indicators of health and physiological status in goats. …”
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Interrelationship between altered metabolites and the gut microbiota in people living with HIV with different immune responses to antiretroviral therapy by Xuebin Tian, Zhongyao Gao, Yiwen Xie, Xiangyun Lu, Yulong Zhao, Peng Yao, Mingqing Dong, Lifeng Yu, Nanping Wu

“…This study explores the connections among immune responses, metabolites, and the gut microbiota in PLWH with differing reactions to ART. Methods: We analyzed the gut microbiota composition, metabolites, and immune markers in 38 PLWH who showed an immunological response (IR) and 32 who did not (INR), as classified according to CD4+ T-cell levels after 24 months of ART. …”
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Heavy grazing intensifies antagonistic effects of nitrogen and phosphorus addition on the water use efficiency of grasslands in Inner Mongolia by Xuebao Xu, Shiming Tang, Yanlong Li, Guangyi Lv, Tongrui Zhang, Bin Zhang, Zhaokai Sun, Zhenpeng Liu, Xinning Wang, Hongyun Yao, Cuiping Gao, Xinya Wang, Chongzhi Sun, Fengqin Yuan, Lei Zhang, Chengjie Wang

“…Abstract Background Plant water use efficiency (WUE) is a key indicator of coupling between the carbon and water cycles in grassland ecosystems and is influenced by both grazing and nutrient availability. …”
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Influence of the pH Synthesis of Fe₃O₄ Magnetic Nanoparticles on Their Applicability for Magnetic Hyperthermia: An In Vitro Analysis by Bárbara Costa, Eurico Pereira, Vital C. Ferreira-Filho, Ana Salomé Pires, Laura C. J. Pereira, Paula I. P. Soares, Maria Filomena Botelho, Fernando Mendes, Manuel P. F. Graça, Sílvia Soreto Teixeira

“…<b>Methods</b>: For the hydrothermal synthesis, FeCl₃·6H₂O and FeCl₂·4H₂O were mixed with different quantities of NaOH to adjust the pH. …”
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Characterizing Nonculprit Lesions and Perivascular Adipose Tissue of Patients Following Acute Myocardial Infarction Using Coronary Computed Tomography Angiography: A Comparative St... by Xiaomeng Wang, Ching H. Sia, Philip D. Adamson, Charlotte E. Greer, Weimin Huang, Hwee K. Lee, Shuang Leng, Yan T. Loong, Nur A. S. Raffiee, Swee Y. Tan, Sock H. Tan, Lynette L. S. Teo, Sung L. Wong, Xiaoxun Yang, Min S. Yew, Thon H. Yong, Liang Zhong, Leslee J. Shaw, Mark Y. Y. Chan, Derek J. Hausenloy, Lohendran Baskaran

“…Background The comparison of coronary computed tomography angiography plaques and perivascular adipose tissue (PVAT) between patients with acute myocardial infarction (AMI) posttreatment and patients with stable coronary artery disease is poorly understood. …”
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Prognostic impact of coronary microvascular dysfunction in patients with myocardial infarction evaluated by new angiography-derived index of microvascular resistance by Benoit Caullery, Laurent Riou, Stephanie Marliere, Estelle Vautrin, Nicolas Piliero, Olivier Ormerzzano, Helene Bouvaist, Gerald Vanzetto, Gilles Barone-Rochette

“…Background: Several methods for measuring IMR derived from angiography have been developed. …”
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Traditional ecological knowledge for great ape conservation in Gabon by Mohamed H. Mohamed-Djawad, Neil M. Longo-Pendy, Serge Ely Dibakou, Costanza Puppo, Jean Nzue-Nguema, Désiré Otsaghe-Ekore, Patrice Makouloutou-Nzassi, Cyr Moussadji-Kinga, Alain P. Kouga, Barthelemy Ngoubangoye, Pape Ibnou Ndiaye, Larson Boundenga

“…Abstract Background Traditional ecological knowledge (TEK) held by Indigenous communities is increasingly recognised as a cost effective, locally adapted complement to instrument-based wildlife monitoring. …”
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