A Novel Metabolic Risk Classification System Incorporating Body Fat, Waist Circumference, and Muscle Strength by Carlos Raúl Robledo-Millán, María Regina Diaz-Domínguez, Ari Evelyn Castañeda-Ramírez, Efrén Quiñones-Lara, Sebastián Valencia-Marín, Ricardo Xopán Suárez-García, Nely Gisela López-Desiderio, Claudio Adrían Ramos-Cortés, Areli Marlene Gaytán Gómez, Juan Manuel Bello-López, Héctor Iván Saldívar-Cerón

“…It aims to improve risk stratification and evaluate the association with metabolic syndrome. <b>Methods</b>: This cross-sectional study involved 300 young adults (18–22 years) from a university in Mexico City, utilizing body composition (%BF) and anthropometric measures (WC, GS) to categorize them into four risk groups: protective, low risk, increased risk, and high risk. …”
Get full text

Fluctuating saline conditions favor competition of Bolboschoenus planiculmis, a dominant species in inland salt marshes by Lingxi Wang, Hongxiang Zhang, Yitong Tao, Tao Zhang, Xiaoqing Li, Xiaoqian Yu, An Yan, Chunguang He, Wei Zheng, Yingzhi Gao

“…Abstract Background The changing hydrological conditions in wetland ecosystems are often accompanied by salt fluctuations. …”
Get full text

Low-Power Vibrothermography for Detecting Barely Visible Impact Damage in CFRP Laminates: A Comparative Imaging Study by Zulham Hidayat, Muhammet Ebubekir Torbali, Nicolas P. Avdelidis, Henrique Fernandes

“…These findings demonstrate that LVT, when combined with PCA or RPCA, offers a reliable method for identifying BVID and can support safer, more efficient structural health monitoring of composite materials.…”
Get full text

Metabolic and Structural Consequences of GM3 Synthase Deficiency: Insights from an HEK293-T Knockout Model by Elena Chiricozzi, Giulia Lunghi, Manuela Valsecchi, Emma Veronica Carsana, Rosaria Bassi, Erika Di Biase, Dorina Dobi, Maria Grazia Ciampa, Laura Mauri, Massimo Aureli, Kei-ichiro Inamori, Jin-ichi Inokuchi, Sandro Sonnino, Maria Fazzari

“…<b>Background</b>: GM3 Synthase Deficiency (GM3SD) is a rare autosomal recessive neurodevelopmental disease characterized by recurrent seizures and neurological deficits. …”
Get full text

Circulating Microvesicles Enriched in miR–126–5p and miR–223–3p: Potential Biomarkers in Acute Coronary Syndrome by José Rubicel Hernández-López, Mirthala Flores-García, Esbeidy García-Flores, Benny Giovanni Cazarín-Santos, Marco Antonio Peña-Duque, Fausto Sánchez-Muñoz, Martha Alicia Ballinas-Verdugo, Hilda Delgadillo-Rodríguez, Marco Antonio Martínez-Ríos, Eduardo Angles-Cano, Aurora de la Peña-Díaz

“…<b>Methods.</b> Bioinformatic tools identified miRNAs linked to ACS. …”
Get full text

Effects of antibiotic therapy on the early development of gut microbiota and butyrate-producers in early infants by Jun Qiu, Jun Qiu, Sha Wu, Sha Wu, Ruiwen Huang, Zhenyu Liao, Xiongfeng Pan, Kunyan Zhao, Kunyan Zhao, Yunlong Peng, Yunlong Peng, Shiting Xiang, Yunhui Cao, Yunhui Cao, Ye Ma, Zhenghui Xiao, Zhenghui Xiao

“…BackgroundAntibiotics, as the most commonly prescribed class of drugs in neonatal intensive care units, have an important impact on the developing neonatal gut microbiota. …”
Get full text

Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients With Type 2 Diabetes by Wagner S. Dantas, Elizabeth C. Heintz, Elizabeth R. M. Zunica, Jacob T. Mey, Melissa L. Erickson, Kathryn P. Belmont, Analisa L. Taylor, Gangarao Davuluri, Hisashi Fujioka, Ciarán E. Fealy, Charles L. Hoppel, Christopher L. Axelrod, John P. Kirwan

“…ABSTRACT Background Activation of mitochondrial fission and quality control occur early in the onset of insulin resistance in human skeletal muscle. …”
Get full text

Novel potential biomarkers for predicting childhood caries via metagenomic analysis by Hui Zhang, Hui Zhang, Xiao Zheng, Xiao Zheng, Xiao Zheng, Yongmao Huang, Yongmao Huang, Yuanqiang Zou, Tao Zhang, Maria Alice Repo, Maria Alice Repo, Meixiang Yin, Yang You, Zhuye Jie, Wen-an Xu, Wen-an Xu

“…BackgroundDental caries is a prevalent global health issue, particularly among children, with significant oral and overall health implications. …”
Get full text

Effect of mixed protein supplementation on golf performance and muscle function: a randomized, double-blind, placebo-controlled study by Ji-Won Seo, Shu Jiang, Soyoung Ahn, Yu Seon Kang, Yunho Sung, Xinxing Li, Parivash Jamrasi, Eun Mi Sun, Jihee Yoo, Byung-Yong Kim, Hyunsu Sim, Wook Song

“…Background As a relatively novel approach to enhancing skeletal muscle health, mixed protein supplementation has shown similar responses to whey protein. …”
Get full text

Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacement by Xiao-Yi Xiong, Xiao-Yi Xiong, Xiao-Yi Xiong, Haicheng Yuan, Ying Mu, Yi He, Fang Xie, Xiao-Shuang Feng, Jia-Xin Xie, Xin-Ru Pan, Yu-Fei Wang, Jian Gong, Xiaoming Zheng, Peng-Fei Wang

“…BackgroundMyeloid cells, such as resident microglia (MG), infiltrating monocytes (Mo), macrophages (MΦ), and CNS border-associated macrophages (BAM) in the brain, participate in aged brain injury. …”
Get full text

Effects of a multicomponent exercise regimen on subchondral bone and cartilage in postmenopausal women with knee osteoarthritis: protocol for a randomized controlled trial by Ville-Markus Konola, Jari Parkkari, Juhani Multanen, Riku Nikander, Timo Rantalainen, Johanna Vesanto, Satu Pekkala, Merja Kalaja, Johanna K. Ihalainen, Benjamin Waller, Matti Munukka, Harri Sievänen, Mika Nevalainen, Hannu Kautiainen, Victor Casula, Juha Paloneva, Tommi Vasankari, Arttu Peuna, Simo Saarakkala, Miika T. Nieminen, Ari Heinonen

“…Abstract Background Knee osteoarthritis (KOA) is considered a whole-joint disease that is amenable to prevention and treatment in the early stages. …”
Get full text

Potential effects of Asian-adapted Mediterranean diet in depression and anxiety among women with metabolic dysfunction-associated steatotic liver disease: a secondary analysis by Alicia Salamanca-Sanabria, Yu Chung Chooi, Evelyn Xiu Ling Loo, Evelyn Xiu Ling Loo, Xianning Lai, Vera Sergeyevna Brok Volchanskaya, Yap Seng Chong, Yap Seng Chong, Johan Gunnar Eriksson, Johan Gunnar Eriksson, Johan Gunnar Eriksson, Johan Gunnar Eriksson, Johan Gunnar Eriksson

“…We previously reported that a calorie-restricted MD adapted to the Asian food culture has beneficial effects on body composition, liver fat, and cardiometabolic markers in Chinese Singaporean women with MASLD.ObjectiveThis secondary analysis examines the effects of an Asian-adapted MD on the symptoms of anxiety and depression in the same population.MethodsIn a double-blind, parallel-design, randomized controlled trial, 84 Chinese- Singaporean females with MASLD were randomly assigned to 1 of the 3 groups for 12 weeks: adapted Asian MD with C15:0 supplementation (n = 29), diet without C15:0 supplementation (n = 26), or control (habitual diet and no C15:0 supplementation, n = 29). …”
Get full text

A platform for multisite immune profiling of premetastatic pancreatic cancer at single-cell resolution by Elishama N. Kanu, Ashley A. Fletcher, Jiayin Bao, Ethan S. Agritelley, Julia Button, Austin M. Eckhoff, Karrie Comatas, Tao Wang, Bin-Jin Hwang, Michael E. Lidsky, Sabino Zani, Dan G. Blazer, Peter J. Allen, Zhicheng Ji, Frank J. Lowery, Sri Krishna, Nicholas D. Klemen, Daniel P. Nussbaum, Erika J. Crosby

“…Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is characterized by exceedingly high rates of metastatic progression, with the liver representing the most common site of distant spread. …”
Get full text

Association between birth length, linear growth velocities, and primary school achievement at age 10 years: evidence from the Ethiopian iABC birth cohort by Rahma Ali, Beakal Zinab, Bikila S. Megersa, Daniel Yilma, Tsinuel Girma, Alemseged Abdissa, Melkamu Berhane, Bitiya Admasu, Suzanne Filteau, Dorothea Nitsch, Henrik Friis, Jonathan C. K. Wells, Gregers S. Andersen, Mubarek Abera, Mette F. Olsen, Rasmus Wibaek, Akanksha A. Marphatia

“…We assessed associations between birth length, childhood linear growth velocities, and stunting with school achievement. Methods Newborns were recruited into the Ethiopian infant Anthropometry and Body Composition (iABC) birth cohort and followed from birth to 10 years. …”
Get full text

Endurance running during late murine adolescence results in a stronger anterior cruciate ligament and flatter posterior tibial slopes compared to controls by Danielle N. Ochocki, Benjamin E. Loflin, Taeyong Ahn, Kaitlyn A. Colglazier, Andrew R. Young, Anna A. Snider, Elizabeth P. Bueckers, Edward M. Wojtys, Stephen H. Schlecht

“…Abstract Background Anterior cruciate ligament (ACL) injury rates continue to rise among youth involved in recreational and competitive athletics, requiring a better understanding of how the knee structurally and mechanically responds to activity during musculoskeletal growth. …”
Get full text

ITIH4 alleviates OVA-induced asthma by regulating lung-gut microbiota by Yi-Hsuan Liu, Yueh-Lun Lee, Chia-Li Han, Yu-Chun Lo, Zih-An Liao, Yu-Syuan Shih, Yi-Wen Lin, Syue-Wei Peng, Kang-Yun Lee, Shu-Chuan Ho, Sheng-Ming Wu, Cheng-Wei Lin, Kian Fan Chung, Jer-Hwa Chang, Hsiao-Chi Chuang

“…Abstract Background Inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4), a Type 2 acute phase protein, is critical for resolving inflammation and promoting tissue repair. …”
Get full text

Varied cellular abnormalities in thin vs. normal endometrium in recurrent implantation failure by single-cell transcriptomics by Xiaoying Fu, Xiaoyan Guo, Han Xu, Yini Li, Bihui Jin, Xirong Zhang, Chongyi Shu, Yuhang Fan, Yiqi Yu, Yuqing Tian, Jiao Tian, Jing Shu

“…Abstract Background Reduced endometrium thickness and receptivity are two important reasons for recurrent implantation failure (RIF). …”
Get full text

Investigation of Bioactive Compounds Extracted from <i>Verbena officinalis</i> and Their Biological Effects in the Extraction by Four Butanol/Ethanol Solvent Combinations by Dejan Stojković, Nikoleta Đorđevski, Mladen Rajaković, Biljana Filipović, Jelena Božunović, Stefani Bolevich, Gokhan Zengin, Sergey Bolevich, Uroš Gašić, Marina Soković

“…<b>Background/Objectives</b>: <i>Verbena officinalis</i> L. …”
Get full text

Safety, Immunogenicity and Protective Activity of a Modified Trivalent Live Attenuated Influenza Vaccine for Combined Protection Against Seasonal Influenza and COVID-19 in Golden S... by Ekaterina Stepanova, Victoria Matyushenko, Daria Mezhenskaya, Ekaterina Bazhenova, Tatiana Kotomina, Alexandra Rak, Svetlana Donina, Anna Chistiakova, Arina Kostromitina, Vlada Novitskaya, Polina Prokopenko, Kristina Rodionova, Konstantin Sivak, Kirill Kryshen, Valery Makarov, Larisa Rudenko, Irina Isakova-Sivak

“…Background/Objectives: Influenza viruses and SARS-CoV-2 are currently cocirculating with similar seasonality, and both pathogens are characterized by a high mutational rate which results in reduced vaccine effectiveness and thus requires regular updating of vaccine compositions. …”
Get full text

Efficacy and mechanism of long-snake moxibustion for treating insomnia in breast cancer survivors: study protocol for a randomized controlled trial by Cuicui Gong, Huakang Li, Qiang Li, Pengxuan Gu, Qi Xiao, Yunjing Jia, Qian Xiao, Yuanzhen Mi, Shanshan Wei, Ziliang Wu, Bing Lin, Zhonglin Zhang

“…BackgroundInsomnia (difficulty falling or staying asleep) is a common issue among breast cancer survivors, significantly impacting their quality of life. …”
Get full text