Prevalence and Associated Factors of Sarcopenic Obesity Among Nursing Home Residents: A Cross‐Sectional Multi‐Centre Study by Doris Eglseer, Hristo Hristov, Sanja Krušič, Nadan Gregorič, Irena Hren, Igor Pravst, Živa Lavriša

“…ABSTRACT Background Obesity and sarcopenia are prevalent among older adults and associated with adverse health outcomes. …”
Get full text

Correction of regulatory molecules expression at the inflammation stage using photobiomodulation therapy in chronic wound modeling by М.V. Kumechko, N.М. Babenko, S.B. Pavlov, О.B. Litvinova, І.І. Torianyk, О.І. Babaieva

“…Background. The search for effective treatments for chronic wounds continues. …”
Get full text

Taurine alleviated paraquat-induced oxidative stress and gut-liver axis damage in weaned piglets by regulating the Nrf2/Keap1 and TLR4/NF-κB signaling pathways by Chen Chen, Min Qi, Weilong Zhang, Fanxing Chen, Zhihong Sun, Weizhong Sun, Wenjie Tang, Zhenguo Yang, Xuan Zhao, Zhiru Tang

“…Abstract Background Oxidative stress can impair intestinal barrier function and cause liver damage, resulting in reduced animal productivity. …”
Get full text

Limosilactobacillus reuteri prevents progression of ankylosing spondylitis in mice by restoring gut microbiota-metabolism homeostasis by Lianjun Yang, Ke You, Kun Wang, Bin Liu, Tao Chen, Zhifei Cui, Dawei Zhang, Zhihai Su, Xiang Liu, Hai Lu

“…Abstract Background Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by progressive spinal fusion and systemic inflammation. …”
Get full text

Rehabilitation after bone marrow transplant compared with usual care to improve patient outcomes (REBOOT): protocol for a randomised controlled trial by Linda Denehy, Shaza Abo, Christopher Swain, Camille E. Short, Nicole Kiss, Amit Khot, Eric Wong, Duncan Purtill, Clare O’Donnell, Marlena Klaic, Catherine L. Granger, Michelle Tew, Tim Spelman, Vinicius Cavalheri, Lara Edbrooke, on behalf on the REBOOT research team

“…Abstract Background Haematological cancer affects more than 1.3 million people around the world annually and accounted for almost 800,000 deaths globally in 2020. …”
Get full text

The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population. by Nathalie Chami, Michael Preuss, Ryan W Walker, Arden Moscati, Ruth J F Loos

“…<h4>Background</h4>Melanocortin 4 receptor (MC4R) deficiency, caused by mutations in MC4R, is the most common cause of monogenic forms of obesity. …”
Get full text

Effect of screw pressing temperature on yield, bioactive compounds, and quality of hemp (Cannabis sativa L.) seed oil by Aymane Allay, Abdessamad Ben Moumen, Youssef Rbah, Marie-Laure Fauconnier, Jacques Nkengurutse, Hana Serghini Caid, Ahmed Elamrani, Farid Mansouri

“…This study aims to assess the effects of different screw press extraction temperatures on hemp oil yield, composition and quality. Methods The study was conducted to examine the influence of screw press extraction temperatures (30, 60, 80, 100, 120 and 140 °C) on hemp oil yield and quality. …”
Get full text

A1 protein free milk benefits mood and subjective cognition in free-living Australian adults: a pragmatic, exploratory, open label randomised controlled trial by Carlene Starck, Michelle Blumfield, Peter Petocz, Emily Duve, Lucy Downey, Kylie Abbott, Flavia Fayet-Moore, Flavia Fayet-Moore

“…BackgroundAdverse effects of milk containing A1-type β-casein on digestion, immune response, and cognition have been identified in milk-intolerant individuals, but health effects in healthy individuals without symptoms of milk intolerance are yet to be examined.ObjectiveThe objective was to explore the impact of reducing A1 type β-casein intake via switching milk type from conventional A1/A2-type β-casein milk (A1/A2 milk) to A1-type β-casein protein free milk (A1PF) on brain, immune response, gastrointestinal, and skin (BIGS) outcomes in a real-world setting.MethodsAn open-label, pragmatic, exploratory randomised controlled trial was conducted in 997 healthy, free-living Australian older adolescents and adults (16–65 years) who regularly consume A1/A2 protein-containing milk and milk products. …”
Get full text

A comprehensive analysis of the tryptophan metabolism-related gene signature to predict the prognosis of esophageal squamous cell carcinoma based on multi-omics by Zhengjie Wu, Zhiping Liu, Yukun Wang, Geling Teng, Xiaodong Li, Tong Lu, Fangning Hu, Shuo Wu, Guanqiang Ma, Hua Zhang

“…BackgroundTryptophan (Trp) metabolism plays a vital role in tumor development and outcomes. …”
Get full text

Intranasal Transplantation of Microbiota Derived from Parkinson’s Disease Mice Induced Astrocyte Activation and Neurodegenerative Pathology from Nose to Brain by Yi-Meng Xia, Mei-Xuan Zhang, Xiao-Yu Ma, Lu-Lu Tan, Ting Li, Jian Wu, Ming-An Li, Wei-Jiang Zhao, Chen-Meng Qiao, Xue-Bing Jia, Yan-Qin Shen, Chun Cui

“…Background: Parkinson’s disease (PD) is characterized by early-onset olfactory dysfunction preceding motor symptoms, yet its mechanisms remain elusive. …”
Get full text

Exploring the impact of chronic intermittent EU-GMP certified Cannabis sativa L. therapy and its relevance in a rat model of aging by Ivona-Maria Tudorancea, Gabriela-Dumitrita Stanciu, Carmen Solcan, Mitica Ciorpac, Andrei Szilagyi, Daniela-Carmen Ababei, Raluca-Maria Gogu, Bogdan-Ionel Tamba

“…Abstract Background Aging is a multifaceted process marked by the progressive accumulation of cellular damage in various tissues, resulting in a decline in physiological functions. …”
Get full text

Success Factors of Growth-Stage Digital Health Companies: Systematic Literature Review by Estelle Pfitzer, Laura Bitomsky, Marcia Nißen, Christoph Kausch, Tobias Kowatsch

“… BackgroundOver the past decade, digital health technologies (DHTs) have grown rapidly, driven by innovations such as electronic health records and accelerated by the COVID-19 pandemic. …”
Get full text

Food additive mixtures and type 2 diabetes incidence: Results from the NutriNet-Santé prospective cohort. by Marie Payen de la Garanderie, Anaïs Hasenbohler, Nicolas Dechamp, Guillaume Javaux, Fabien Szabo de Edelenyi, Cédric Agaësse, Alexandre De Sa, Laurent Bourhis, Raphaël Porcher, Fabrice Pierre, Xavier Coumoul, Emmanuelle Kesse-Guyot, Benjamin Allès, Léopold K Fezeu, Emmanuel Cosson, Sopio Tatulashvili, Inge Huybrechts, Serge Hercberg, Mélanie Deschasaux-Tanguy, Benoit Chassaing, Héloïse Rytter, Bernard Srour, Mathilde Touvier

“…<h4>Background</h4>Mixtures of food additives are daily consumed worldwide by billions of people. …”
Get full text

Effect of atrial fibrosis on clot burden score and physicochemical properties of thrombus in patients with ischaemic stroke occurring in non-valvular atrial fibrillation by Juan Zhao, Guangjun Deng, Weijing Wang, Peng Wang, Xinyu Shen, Xiaoxiao Yuan, Haifei Jiang, Zhong-bao Ruan

“…Methods A total of 117 patients with AIS in NVAF attending the Department of Cardiovascular Medicine and the Cerebrovascular Diagnostic and Treatment Centre between August 2021 and May 2024 were included in the study. …”
Get full text

Effects of ketogenic diets on polycystic ovary syndrome: a systematic review and meta-analysis by Rossella Cannarella, Michele Rubulotta, Alessia Leonardi, Andrea Crafa, Antonio Calvo, Federica Barbagallo, Sandro La Vignera, Aldo E. Calogero

“…Methods A systematic search was conducted across Scopus, PubMed, Cochrane, and Embase databases from their inception through January 2025, using a predefined search strategy. …”
Get full text

Single-cell RNA sequencing of human double-negative T cells reveals a favorable cellular signature for cancer therapy by Li Zhang, Sergio Rutella, Jongbok Lee, Ismat Khatri, Yoosu Na, Enoch Tin, Karen Fang, Michele Nawata, Juan Arteaga, Mark D Minden

“…Background Allogeneic double-negative T-cell (DNT) therapy has emerged as a novel, off-the-shelf cellular treatment with clinical feasibility, safety, and promising efficacy against leukemia. …”
Get full text

Plant Dominant Low-Protein Diet, Nutritional Status (Phase Angle) and Progression of Renal Failure: Case-Report Study by Danijela Ristic-Medic, Snjezana Petrovic, Biljana Pokimica, Marija Paunovic, Vesna Vucic

“…Background and Objectives: High dietary protein intake can cause intraglomerular hypertension, which may result in kidney hyperfiltration, glomerular injury, and proteinuria. …”
Get full text

Chronic stress is associated with altered gut microbiota profile and relevant metabolites in adolescents by Li Ying, Wang Yuhao, He Yafang, Lan Jiao, Dang Lina, Song Qinze, Yang Chenghai, Zhao Shaoxiong, Gu Yuexi, Shen Mingwang, Cai Zelin, Wang Chuangchuang, Guo Zihan, Liu Xin, Ma Lu, Zhang Lei

“…Abstract Background Gut microbiota and microbiota-derived metabolites have been implicated in the regulation of stress-related diseases, yet their associations with chronic stress in adolescents remain unclear. …”
Get full text

Methodology and application of multiplex PCR-dipstick DNA chromatography for the detection of eight respiratory bacterial pathogens by Liuyang Hu, Xiuri Wang, Qiong Li

“…BackgroundCommunity-acquired pneumonia is primarily caused by Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Mycoplasma pneumoniae, and Chlamydia pneumoniae, leading to severe illness and death in developing countries.MethodsA rapid, straightforward, sensitive, high-throughput, and precise multiplex PCR-dipstick DNA chromatography assay was devised. …”
Get full text

Biological maturation determines the beneficial effects of high-intensity functional training on cardiorespiratory fitness in male adolescents by Jarosław Domaradzki, Cristian Alvarez, Rafał Szafraniec, Dawid Koźlenia

“…Background During adolescence, between 15–18 years of age, biological maturation is associated with changes in body composition, blood pressure (BP), and cardiorespiratory fitness (CRF). …”
Get full text