New bitongling regulates gut microbiota to predict angiogenesis in rheumatoid arthritis via the gut-joint axis: a deep neural network approach by Yin Guan, Xiaoqian Zhao, Yun Lu, Yue Zhang, Yan Lu, Yue Wang

“…BackgroundRheumatoid arthritis (RA) is a persistent autoimmune disorder marked by inflammation and joint damage. …”
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Protein kinase CK2 sustains de novo fatty acid synthesis by regulating the expression of SCD-1 in human renal cancer cells by Barbara Guerra, Kristina Jurcic, Rachelle van der Poel, Samantha Lynn Cousineau, Thomas K. Doktor, Laura M. Buchwald, Scott E. Roffey, Caroline A. Lindegaard, Anna Z. Ferrer, Mohammad A. Siddiqui, Laszlo Gyenis, Brage S. Andresen, David W. Litchfield

“…Abstract Background Clear cell renal cell carcinoma (ccRCC) is a type of cancer characterized by a vast intracellular accumulation of lipids that are critical to sustain growth and viability of the cells in the tumour microenvironment. …”
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The Effects of Dietary Supplementation of Chestnut Tannic Acid on the Growth Performance, Gut Morphology and Microbiota of Weaned Piglets by Jinzhou Zhang, Yuting Zhang, Yuya Wang, Yanwei Li, Dongyang Liu, Hongbing Xie, Yongqiang Wang, Meinan Chang, Liping Guo, Zhiguo Miao

“…<b>Background/Objectives</b>: This study investigated the effects of chestnut tannic acid (TA) on the growth performance, the expression of tight junction proteins and the composition of the gut microbiota of weaned piglets, which could provide novel insights into the application of TA in swine production. …”
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Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of can... by Judy M Coulson, Joseph J Sacco, Michael Shackcloth, Alexander Haragan, Doris M Rassl, Harish Poptani, Anne Herrmann, Liam Shaw, Sarah Barnett, Jan Schulze

“…Background Pleural mesothelioma is a cancer of the lung lining associated with asbestos exposure. …”
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Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of can... by Judy M Coulson, Joseph J Sacco, Michael Shackcloth, Alexander Haragan, Doris M Rassl, Harish Poptani, Anne Herrmann, Liam Shaw, Sarah Barnett, Jan Schulze

“…Background Pleural mesothelioma is a cancer of the lung lining associated with asbestos exposure. …”
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The immunogenic potential of an optimized mRNA lipid nanoparticle formulation carrying sequences from virus and protozoan antigens by Renata S. Fernandes, Gabriela de Assis Burle-Caldas, Sarah Aparecida Rodrigues Sergio, Ana Flávia Bráz, Nathália Pereira da Silva Leite, Milton Pereira, Juliana de Oliveira Silva, Natália Satchiko Hojo-Souza, Bianca de Oliveira, Ana Paula S. Moura Fernandes, Flávio Guimarães da Fonseca, Ricardo Tostes Gazzinelli, Diego dos Santos Ferreira, Santuza M. Ribeiro Teixeira

“…Results Using firefly luciferase (Luc) as a reporter mRNA, we evaluated the physical–chemical properties, stability, and biodistribution of an LNP-mRNA formulation produced using a novel lipid composition and a microfluidic organic-aqueous precipitation method. …”
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Shramahara Mahakasya, a traditional polyherbal formulation, induces anti-anxiety activity in hippocampal neurons by effectuating SOD2-mediated protection against oxidative stress by Saakshi Saini, Viney Kumar, Swati Haldar, Samrat Chauhan, Pratibha Demiwal, Souvik Ghosh, Sumeet Gupta, Debabrata Sircar, Bidhan Mahajon, Partha Roy

“…In this study, we investigated the intricate mechanisms through which SM polyherbal extract exerts neuroprotective and anxiolytic effects in cultured HT-22 cells and rodent models. Method: In this study, the chemical composition of SM was first identified using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS). …”
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Evaluation of a novel simulation-based training for urgent laryngectomy care by Freya Sparks, Nicky Gilbody, Katerina Hilari

“…Methods A simulation-based training programme was piloted with delegates from a range of healthcare professions, over three separate study days. …”
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The Impact of Orthodontic Adhesives on the Subgingival Microbiota During Early Fixed Appliance Therapy: A Pilot Study by Krisztina Martha, Esztella-Éva Kis, Izabella Éva Mureșan, Andrei Constantin Ioanovici

“…<i>Background and Objectives</i>: The most common method for treating malocclusions today is fixed orthodontic therapy, during which brackets and tubes are bonded to the surface of the teeth, which makes oral hygiene difficult to maintain. …”
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Urinary metabolites as biomarkers of dietary intake: a systematic review by Mariah Kay Jackson, Bing Wang, Heather Rasmussen, Sathish Kumar Natarajan, Sathish Kumar Natarajan, Laura D. Bilek, Diane K. Ehlers, Laura Graeff-Armas, Christopher D’Angelo, Teresa Cochran, Kimberly Harp, Corrine Hanson

“…BackgroundCurrent diet assessment tools, such as food frequency questionnaires, may result in misclassification bias from measurement error and misreporting. …”
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Industrial Packaging Performance Indicator Using a Group Multicriteria Approach: An Automaker Reverse Operations Case by Marcelo Miguel da Cruz, Rodrigo Goyannes Gusmão Caiado, Renan Silva Santos

“…It was prioritized through the analytic hierarchy process (AHP)-GDM method, combining judgments to establish a structured technical consensus. …”
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The triple radiologic asthma phenotype is associated with worse disease control by Rory Chan, MBChB, PhD, Chary Duraikannu, FRCR, Mohamed Jaushal Thouseef, FRCR, Brian Lipworth, MD

“…Methods: A total of 112 patients with moderate-to-severe asthma were included in this retrospective observational study. …”
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Dendritic Gold Nanoparticles Loaded on 3D Graphene-like Surface and Layer-by-Layer Assembly for Enhanced Glucose Biosensing by Zifeng Zhu, Yiming Zhao, Yongming Ruan, Xuexiang Weng, Gesmi Milcovich

“…Background/Objectives: In this study, AuDNs/EPLE composite electrodes with hierarchical dendritic nanogold structures were fabricated using the in situ electrodeposition of gold nanoparticles through the <i>i</i>-<i>t</i> method. …”
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Psychometric analysis of work organization and fatigue instruments and their relationship with occupational accidents: a structural equation modeling approach by Mohammad Khandan, Ali Montazeri, Ali Ebrahimi

“…This study aimed to evaluate the psychometric properties of instruments measuring work organization and fatigue and to examine their relationship with occupational accidents. Methods A cross-sectional study was conducted in 2019 with 200 nurses working in hospitals in Qom, Iran using the stratified sampling method. …”
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Phytochemical components and antibacterial activity of two populations of Senecio vulgaris L. essential oils as traditional medicine plant by Fatemeh Hajmoradi, Hamed Fathi, Foozieh Moghadami

“… Background and Objectives: Senecio vulgaris L., a member of the Asteraceae family, has been widely employed in traditional Iranian herbal practices for centuries. …”
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Efficacy of a gelatin-based hemostatic sponge and hydroxyapatite-chitosan nanocomposites (nHAp/CS) on regeneration of radial bone defects in rabbits by Taher Naser Elmeshreghi, Fathy D. El-Seddawy, Mohamed Gomaa, Shimaa A. Ezzeldein, Mustafa Abd El Raouf

“…Background: Bone-graft substitutes are a frequently employed method for the clinical reconstruction of osseous bone defects, and research on synthetic biomaterials is currently ongoing. …”
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Influence of the Cultivator Working Body Parameters on the Soil Crumbling Quality by S. I. Kambulov, G. G. Parkhomenko, O. S. Babenko, I. V. Bozhko

“…It was shown that soil is a specific type of natural resource that can be renewed when reasonably cultivated by various tillage methods. It requires the availability of working bodies that meet the qualitative agrotechnical indicators of the technological process. …”
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Advancing neuroprotection and atherosclerosis prevention through familial hypercholesterolemia management: Analyzing comorbidity burden with stroke, coronary heart disease, hyperte... by Jingjia Wang, Sicong Liu, Ming Zhang, Xiangbin Meng, Xuliang Wang, Wenyao Wang, Jun Gao, Jilin Zheng, Zhiyun Yang, Jun Wen, Da Liu, Lin Yang, Chen Wei, Siyan Zhan, Pei Gao, Chunli Shao

“…This study aimed to investigate the comorbidity burden of FH in China and analyze the differences between familial and general hypercholesterolemia (HC) populations. Methods Using a national medical insurance database from 2013 to 2017 including 13,976 patients with FH and 13,976 matched control patients with HC, we utilized case‐control methods to compare the composition ratio, comorbidity rates, medical expenses, and healthcare burden of patients with FH to those of control patients. …”
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Guideline-Based Digital Exercise Interventions for Reducing Body Weight and Fat and Promoting Physical Activity in Adults With Overweight and Obesity: Systematic Review and Meta-An... by Mohamad Motevalli, Clemens Drenowatz, Derrick Tanous, Gerhard Ruedl, Werner Kirschner, Markus Schauer, Thomas Rosemann, Katharina Wirnitzer

“…However, their superiority over traditional methods is uncertain for BMI and body composition. …”
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Vaginal microbiota: different roles of lactobacilli and community instability in chronic vulvovaginal discomfort by Vladimír Buchta, Vladimír Buchta, Jana Nekvindová, Daniel Leško, Filip Vrbacký, Peter Veščičík, Zuzana Uhlířová, Ctirad Andrýs, Radka Bolehovská, Marian Kacerovský, Jiří Špaček, Alena Mrkvicová, Hana Skalská, Lenka Plíšková

“…BackgroundChronic vulvovaginal discomfort (CVD) is a complex syndrome with many unresolved questions regarding its etiology, diagnosis, and management in relation to the vaginal microbiota.MethodsCervicovaginal fluid of 91 CVD patients and 35 healthy controls was obtained at the beginning and end of the follow-up period. …”
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