Gender representation in leadership & research: a 13-year review of the Annual Canadian Society of Otolaryngology Meetings by Grace Yi, Jennifer Payandeh, Dorsa Mavedatnia, Penelope Neocleous, Jacob Davidson, Jennifer Siu, Molly Zirkle, Julie E. Strychowsky, M. Elise Graham, Yvonne Chan

“…Abstract Background The gender disparity in surgical disciplines, specifically in speakers across North American medical and surgical specialty conferences, has been highlighted in recent literature. …”
Get full text

Spillover effect of a dietary intervention on physical activity in a randomized controlled trial with colorectal cancer patients by Hege Berg Henriksen, Åshild Kolle, Andreas Stenling, Ingvild Paur, Siv Kjølsrud Bøhn, Pernille Brøto, Tuva Syrdal Tronstad, Rune Blomhoff, Sveinung Berntsen

“…Abstract Background Randomized controlled studies (RCTs) targeting dietary changes may also lead to other, untargeted changes in lifestyle habits, as spillover effects. …”
Get full text

Integrating digital health into pediatric obesity management: Current practices and future perspectives by Vittoria Frattolillo, Alessia Massa, Dalila Capone, Noemi Monaco, Gianmario Forcina, Pierluigi Di Filippo, Pierluigi Marzuillo, Emanuele Miraglia del Giudice, Anna Di Sessa

“…Background: Childhood obesity is a growing global health concern with significant cardiometabolic consequences. …”
Get full text

Association of chronotype and sleep behaviors with mental well-being, eating behaviors, and adiposity traits: a cross-sectional study among a sample of urban Malaysian adults by Yee-How Say, Mimi Shamirah Nordin, Alvin Lai Oon Ng

“…Methods A total of 167 participants were recruited (male/female = 46/121; aged 22.0 ± 5.2). …”
Get full text

Influence of fire characteristics on the associations between smoke PM2.5 exposure and acute cardiorespiratory health events by Calvin S. Riss, Sam D. Faulstich, Patrick S. Reuther, William J. Metcalf, Lyndsey A. Darrow, Heather A. Holmes, Matthew J. Strickland

“…Background: Wildland fire smoke is a significant source of PM2.5 pollution in the western United States, with varying chemical composition and toxicity depending on fire characteristics. …”
Get full text

Hyodeoxycholic Acid Ameliorates Metabolic Syndrome Through Pathways of Primary Bile Acid Synthesis and Fatty Acid Degradation: Insights From a Rat Model by Chen M, Huang K, Luo W, Zhang F, Gan H, Yang Z

“…Hyodeoxycholic acid (HDCA) has shown potential effects in non-alcoholic fatty liver disease (NAFLD), yet its role in MS is unexplored.Aim: This study aims to assess whether HDCA is a characteristic BA of MS and to investigate its intervention effects and potential mechanisms.Methods: We employed 16S rDNA sequencing and UHPLC-MS/MS to investigate the dynamics of the gut microbiota and BA profiles in rats and conducted a correlation study between indices, identifying HDCA as the potential characteristic BA. …”
Get full text

Food additive emulsifiers and cancer risk: Results from the French prospective NutriNet-Santé cohort. by Laury Sellem, Bernard Srour, Guillaume Javaux, Eloi Chazelas, Benoit Chassaing, Emilie Viennois, Charlotte Debras, Nathalie Druesne-Pecollo, Younes Esseddik, Fabien Szabo de Edelenyi, Nathalie Arnault, Cédric Agaësse, Alexandre De Sa, Rebecca Lutchia, Inge Huybrechts, Augustin Scalbert, Fabrice Pierre, Xavier Coumoul, Chantal Julia, Emmanuelle Kesse-Guyot, Benjamin Allès, Pilar Galan, Serge Hercberg, Mélanie Deschasaux-Tanguy, Mathilde Touvier

“…<h4>Background</h4>Emulsifiers are widely used food additives in industrially processed foods to improve texture and enhance shelf-life. …”
Get full text

Physical and chemical characteristics of Aedes larval habitats in Metema District, Northwest, Ethiopia by Wondmeneh Jemberie, Sisay Dugassa, Abebe Animut

“…Abstract Background Aedes-transmitted viral diseases such as dengue, chikungunya, yellow fever, and Zika are increasing public health and economic challenge globally. …”
Get full text

The effects of a semen cuscutae flavonoids-based antidepressant treatment on microbiome and metabolome in mice by Qianfeng Shao, Qianfeng Shao, Sheng Zhou, Yue Li, Lin Jin, Xiaowei Fu, Tong Liu, Tong Liu, Jing Wang, Jing Wang, Shaohui Du, Shaohui Du, Che Chen

“…BackgroundDepression is a prevalent psychiatric disorder and one of the leading causes of disability worldwide. …”
Get full text

Feasibility and preliminary efficacy of an online home-based functional exercise program for Parkinson's disease: a pilot study by Hyungwoo Lee, Hunyoung Ha, Heehyun Shin, Byungjun Park, Nyeonju Kang, Kiwon Park, Ryul Kim, Kyeongho Byun

“…BackgroundParkinson's disease (PD) leads to motor and non-motor impairments, contributing to sarcopenia and reduced functional independence. …”
Get full text

<i>Syzygium aromaticum</i> Phytoconstituents Target SARS-CoV-2: Integrating Molecular Docking, Dynamics, Pharmacokinetics, and <i>miR-21 rs1292037</i> Genotyping by Mustafa Ahmed Muhmood, Faiza Safi, Mohammed Mukhles Ahmed, Safaa Abed Latef Almeani

“…Background and aim: The COVID-19 pandemic, caused by SARS-CoV-2, remains a global health crisis despite vaccination efforts, necessitating novel therapeutic strategies. …”
Get full text

Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapy by Yuanshan Yao, Chunji Chen, Bin Li, Wen Gao

“…Abstract Background The modulation of tumor microenvironments through immune checkpoint pathways is pivotal for the development of effective cancer immunotherapies. …”
Get full text

Liver-Targeting Nanoparticles GA-MSe@AR Treat NAFLD Through Dual Lipid-Lowering and Antioxidant Efficacy by Lei S, Wu Q, Zhang B, Lu M, Xia Y, Li N

“…In this study, selenium-based antioxidant nanoparticles were developed to load and deliver AR to the liver for synergistic AR and selenium effective treatment of NAFLD.Methods: The therapeutic potential of AR was analyzed by network pharmacology. …”
Get full text

Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism by Yang Yang, Yang Yang, Qing Hong, Qing Hong, Xuehong Zhang, Zhenmin Liu, Zhenmin Liu

“…BackgroundRheumatoid arthritis (RA) is a common chronic and systemic autoimmune disease. …”
Get full text

The dietary inflammation index and body mass index mediate the association between the dietary index for gut microbiota and sarcopenia in older women: evidence from NHANES 2011–201... by Xiaoyan Zhang, Liangzhi Wu, Yutian He, Shuyao Zhang, Wenfeng Hua, Wenfeng Hua

“…BackgroundThe dietary index of gut microbiota (DI-GM) was developed to assess dietary quality by reflecting the diversity of the gut microbiota composition. …”
Get full text

Daily Lactose Supplementation in Lactase Non-Persistent Individuals Induces Colonic Adaptation and Reduces Intolerance Symptoms by Ellen Looijesteijn, Lonneke JanssenDuijghuijsen, Maartje van den Belt, Beatrix Gerhard, Renata Ariens, Reina Tjoelker, Jan Geurts

“…Background and objectives: Globally, about 70% of the adult population is lactase non-persistent (LNP), lacking the enzyme required for lactose digestion. …”
Get full text

Microbiome and metabolome patterns after lung transplantation reflect underlying disease and chronic lung allograft dysfunction by Christian Martin, Kathleen S. Mahan, Talia D. Wiggen, Adam J. Gilbertsen, Marshall I. Hertz, Ryan C. Hunter, Robert A. Quinn

“…Abstract Background Progression of chronic lung disease may lead to the requirement for lung transplant (LTx). …”
Get full text

The Effects of Prebiotic Dietary Fibers, Probiotics, and Synbiotics on Gut Permeability and Immunity: A Systematic Review by Leila Maghsoumi-Norouzabad, Alireza Bagherzadeh-Karimi, Shabnam Aliakbari Majd, Leila Hosseini, Fatemeh Shahi

“…Background: Modulation of intestinal barrier, which function through zonulin pathway downregulation, represents a promising therapeutic strategy for chronic diseases. …”
Get full text

Thigh muscle features in female patients with severe knee osteoarthritis: a cross-sectional study by Tingting Liu, Hao Xie, Songhua Yan, Jizhou Zeng, Kuan Zhang

“…Abstract Background Muscle function deterioration in female patients with severe knee osteoarthritis (KOA) is linked to alterations in muscle morphology, composition, and mechanical properties. …”
Get full text

High-fat diet impairs microbial metabolite production and aggravates influenza A infection by Franziska Hornung, Harini K. SureshKumar, Laura Klement, Yasmina Reisser, Christoph Wernike, Vivien Nischang, Paul M. Jordan, Oliver Werz, Carsten Hoffmann, Bettina Löffler, Stefanie Deinhardt-Emmer

“…This study investigates alterations in the gut microbiome during a high-fat diet (HFD), particularly short-chain fatty acids (SCFAs), and how these metabolites affect lung infection caused by Influenza A virus (IAV). Methods We used a HFD-mouse model to evaluate gut microbiota composition, SCFA levels, and pulmonary outcomes following IAV infection. …”
Get full text