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2941
Engineered <i>Escherichia coli</i> Nissle 1917 Expressing IGF1 and FGF19 Reduce Liver Fat Accumulation and Restore Microbial Equilibrium in a Metabolic Dysfunction-Associated Steat...
Published 2024-03-01“…Background and objectives: Endocrine dysregulation and intestinal microbiota unbalance are commonly associated with metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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2942
Potential activity of Ferula macrecolea essential oil for treating Giardia lamblia infection through modulating electrolytes and suppressing NF-κB p65 pathway
Published 2025-02-01“…In light of the previously discussed information and the recognized antimicrobial properties of Ferula macrecolea, this study aims to investigate both the in vitro and in vivo anti-giardial effects of F. macrecolea essential oil (FME) on G. lamblia infection.MethodsGas chromatography-mass spectrometry (GC-MS) was utilized to analyze the chemical composition of the prepared FME. …”
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2943
Characterization of the enteric virome of clinically healthy pigs around weaning on commercial farms in the Netherlands using next generation sequencing and qPCR
Published 2025-07-01“…Abstract Background Enteric virus infections around time of weaning have always been related to pig diseases such as postweaning diarrhea. …”
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2944
Risk factors for decreased bone mineral density in men with type 2 diabetes.
Published 2021-01-01“…BACKGROUND: Type 2 diabetes and osteoporosis are widespread diseases in the middle-aged and elderly people. …”
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2945
Medical Hemorrhoid Gel Ameliorates Croton Oil-Induced Hemorrhoids by Suppressing the NLRP3 Inflammasome Activation via NF-&kappa;B Signaling Pathway
Published 2025-08-01“…This study aims to systematically evaluate the safety, efficacy, and mechanism of action of MHG in treating HD.Methods: The phytochemical composition of MHG was characterized using UPLC-QTOF-MS/MS and GC-MS/MS analyses. …”
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2946
Modulation of the Plasma Lipidomic Profile in Piglets Fed Polar Lipid-Rich Diets
Published 2024-12-01“…<b>Background:</b> Polar lipids from dairy are novel sources of energy that may replace other dietary lipids and impact plasma lipidomic profiles in piglets. …”
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2947
Longitudinal Changes in Peripheral and Alveolar Monocyte and Inflammatory Biomarkers are Distinct in Hypercapnia Patients Following Pulmonary Sepsis-Induced ARDS
Published 2025-04-01“…Our study was designed to compare initial values and longitudinal changes in cellular composition and inflammatory biomarkers between pneumonia sepsis-induced ARDS patients without hypercapnia and hypercapnia patients.Methods: Between Dec 2022-Apr 2023, we prospectively studied 61 severe pneumonia patients. …”
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2948
Rescue of protein dyshomeostasis in hippocampal astrocytes from an Alzheimer’s disease mouse model by stabilizing ER-mitochondrial interactions at a 20 nm distance
Published 2025-07-01“…However, its link to the impairment of the proteolytic system in AD remains unexplored. Methods We used, as a model, hippocampal astrocytes from 3xTg-AD mice expressing either control plasmid or synthetic linkers stabilizing ER-mitochondrial interaction at 10 nm (10 nm-EML) or at 20 nm (20 nm-EML). …”
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2949
Elastic Band Training Versus Multicomponent Training and Group-Based Dance on Morphological Variables and Physical Performance in Older Women: A Randomized Controlled Trial
Published 2024-10-01“…Background: This study aimed to analyze the effects of elastic band training (EBT) versus multicomponent training (MCT) and group-based dance (GBD) on waist circumference, body composition (body fat percentage and fat-free mass), and physical performance (handgrip strength, HGS; 30-s chair stand; timed up-and-go, TUG) in Chilean older women. …”
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2950
The Structure of Acute Exotoxicosis During the First Three Months of the COVID-19 Pandemic (According to the Acute Toxicosis Department of N.V. Sklifosovsky Research Institute for...
Published 2021-04-01“…BACKGROUND The self-isolation regime introduced to limit the spread of COVID-19 disrupted the habitual way of life of the majority of the population, which could cause increased anxiety and depressive states in some citizens and lead to the development of acute exotoxicosis.AIM OF STUDY To identify the impact of the COVID-19 pandemic on the structure of acute poisonings based on their comparative analysis for March-May in 2019 and 2020.MATERIAl AND METHODS “Hospital patient cards” of patients who were treated in the Department of Acute Toxicosis and Somatopsychiatric Disorders of the N. …”
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2951
Malaria epidemics and its drivers in Uganda in 2022
Published 2025-07-01“…Abstract Background In Uganda, malaria is a year-round health threat, with transmission intensity varying across regions. …”
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2952
Association of breast milk microbiota and metabolites with neonatal jaundice
Published 2025-01-01“…BackgroundBreast milk is the primary source of nutrition during early life, and existing research indicates that the development of jaundice in breastfed newborns may be linked to specific nutrients or bioactive substances present in breast milk. …”
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2953
S-values for bone marrow dosimetry in preclinical radiopharmaceutical studies with rodents
Published 2025-07-01“…Abstract Background Development of novel radiopharmaceuticals involves dosimetry calculations to validate safety and aid with selection of those that should be translated into the clinical environment. …”
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2954
Alpine Adaptive Mechanism on Rhizosphere Microbes Recruitment of <i>Crepis napifera</i> (Franch.) Babc. by Multi-Omics Analysis
Published 2025-03-01“…Babc., a regionally significant medicinal plant, contains a diverse array of terpenoids and demonstrates substantial potential for resource development and utilization. <b>Methods:</b> Transcriptome sequencing, metabolomic profiling, and 16S rRNA gene amplicon sequencing were employed to assess the transcriptional expression patterns, metabolic variations, and rhizosphere microbial community composition of <i>C. napifera</i> (Franch.) …”
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2955
The effect of eight weeks of progressive resistance training with garlic supplementation on serum levels of C-reactive protein and insulin resistance in overweight women
Published 2022-06-01“…Background and Purpose: Resistance exercise can reduce inflammation. …”
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2956
Postbiotic-Based Extracts from Native Probiotic Strains: A Promising Strategy for Food Preservation and Antimicrobial Defense
Published 2025-03-01“…<b>Background/Objectives</b>: The deterioration of food quality and safety is often linked to the presence of pathogenic and spoilage microorganisms. …”
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2957
Machine learning-assisted analysis of serum metabolomics and network pharmacology reveals the effective compound from herbal formula against alcoholic liver injury
Published 2025-04-01“…Nevertheless, the effective compound is challenging to identify due to its intricate composition and multiple targets. Methods An integration machine learning-assisted approach was established, whereby the particular action mechanism and direct target were obtained through the correlation of compounds, targets, and metabolites. …”
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2958
Total and regional fat-to-muscle mass ratio and risks of pan-cancer: a prospective cohort study
Published 2025-05-01“…Abstract Background The fat-to-muscle mass ratio (FMR) has served as a marker for various diseases. …”
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2959
Development of the 10-question household foodwork interactional assessment questionnaire (FIA-Q10)
Published 2024-11-01“…Abstract Background Public health nutrition recommendations and clinical dietary interventions emphasize eating healthy food at home, implicitly requiring household foodwork. …”
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2960
The Beneficial Application of Turmeric (Curcuma longa L.) on Health and Egg Production, in Layers: A Review
Published 2024-11-01“…ABSTRACT Background Turmeric (Curcuma longa L.) is a widely recognized spice and medicinal plant that has gained significant attention for its potential health benefits. …”
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