BLOOD-SUCKING MOSQUITOES (DIPTERA, CULICIDAE) OF THE LANDSCAPE PROVINCES OF THE STAVRPOLSKY KRAI-CARRIERS OF MALARIA by S. I. Sigida

“…The first is a zone of sustained risk of malaria transmission; the second is a zone of moderate risk; the third is a zone of low risk. Material and methods of research. The material for this work was the results of field studies, collecting mosquitoes in natural biotopes of various landscapes from May to September in different seasons of 2015-2017 by mowing with a net, by catching "on yourself "[6], in the room with a "test tube", collecting eggs and larvae of 1 - 4 ages from reservoirs. …”
Get full text

Unveiling the diagnostic and pro-inflammatory role of crohn’s disease: insights from 16 S-guided discovery and species-specific validation by Yao Xu, Runxiang Xie, Yuqing Weng, Yewei Fang, Huimin Chen, Shuan Tao, He Zhang, Yawen Ye, Xinyu Deng, Axiang Han, Qi Jiang, Wei Liang

“…Abstract Background The rising incidence of Crohn’s disease (CD) in Asia underscores the need to explore its underlying mechanisms. …”
Get full text

Repurposing of an inotropic drug dobutamine to enhance the production of human hematopoietic stem cells from human induced pluripotent stem cells by Chuti Laowtammathron, Pimonwan Srisook, Pakpoom Kheolamai, Rangsun Parnpai, Chanchao Lorthongpanich, Surapol Issaragrisil

“…Abstract Background Dobutamine hydrochloride (DH), a common inotropic drug used for heart failure, has recently been discovered to inhibit Yes-Associated Protein (YAP). …”
Get full text

Investigation of bacterial microbiota variability in two allopatric populations of Nyssomyia umbratilis, susceptible and nonsusceptible to Leishmania (Viannia) guyanensis infection... by Eric Fabrício Marialva, Keillen Monick Martins-Campos, Victo Ramos de Almeida, Claudia María Ríos-Velasquez, Antônio Jorge Tempone, Felipe Arley Costa Pessoa, Yara Maria Traub-Cseko

“…Abstract Background Sand flies of the species Nyssomyia umbratilis (Diptera: Psychodidae: Phlebotominae) are vectors of the parasite Leishmania (Viannia) guyanensis, one of the etiological agents of cutaneous leishmaniasis in the Amazon region. …”
Get full text

Impacts of Protease Sources on Growth and Carcass Response, Gut Health, Nutrient Digestibility, and Cecal Microbiota Profiles in Broilers Fed Poultry-by-Product-Meal-Based Diets by Muhammad Shahbaz Zafar, Shafqat Nawaz Qaisrani, Saima, Zafar Hayat, Kashif Nauman

“…Methods: In total, 800 one-day-old mixed-sex broilers (Arbor Acres) were weighed and allocated to one of the four dietary treatments in a completely randomized design, with eight replicates and 25 birds each per replicate. …”
Get full text

Bioinformatics meets machine learning: identifying circulating biomarkers for vitiligo across blood and tissues by Qiyu Wang, Jingwei Yuan, Jingwei Yuan, Mengdi Zhang, Haiyan Jia, Hongjie Lu, Yan Wu

“…BackgroundVitiligo is a skin disorder characterized by the progressive loss of pigmentation in the skin and mucous membranes. …”
Get full text

High-intensity resistance and impact training for patients with hormone-sensitive prostate cancer and bone metastases—study protocol of a randomized clinical trial by Anne-Mette Ragle, Marta Kramer Mikkelsen, Anders Vinther, Bo Zerahn, Carsten Bogh Juhl, Susann Theile, Kasper Madsen, Dorte Lisbet Nielsen, Peter Busch Østergren

“…Abstract Background Men with metastatic prostate cancer are at an increased risk of metabolic syndrome, cardiovascular disease, and pathological fracture. …”
Get full text

Sex-specific differences in preclinical models of advanced chronic liver disease and portal hypertension by Peio Aristu-Zabalza, María Andrés-Rozas, Zoe Boyer-Díaz, David P. Al-Adra, Douglas Maya-Miles, Sergi Guixé-Muntet, Anabel Fernández-Iglesias, Jordi Gracia-Sancho

“…Abstract Background Chronic liver disease is a major health concern, but sex-specific differences in its pathophysiology remain unclear. …”
Get full text

The effect of the ketogenic diet on resistance training load management: a repeated-measures clinical trial in trained participants by Salvador Vargas-Molina, Manuel García-Sillero, Diego A. Bonilla, Jorge L. Petro, Jerónimo García-Romero, Javier Benítez-Porres

“…Background The effect of low-carbohydrate high-fat dietary manipulation, such as the ketogenic diet (KD), on muscle strength assessment in resistance-training (RT) participants has focused on the one-repetition maximum test (1-RM). …”
Get full text

Biostimulant-Based Molecular Priming Improves Crop Quality and Enhances Yield of Raspberry and Strawberry Fruits by Petar Kazakov, Saleh Alseekh, Valentina Ivanova, Tsanko Gechev

“…Methods: Metabolome analysis was performed by liquid chromatography–mass spectrometry analysis (LC-MS), and essential elements analysis was performed by inductively coupled plasma-mass spectrometry (ICP-MS). …”
Get full text

Effects of dietary faba bean (Vicia faba L.) inclusion on carcass characteristics, meat quality, and blood biochemistry in Awassi lambs by Belal S. Obeidat, Nawras L. Al Shabuol, Linda Alyahya

“…Background and Aim: The search for sustainable and cost-effective protein alternatives to soybean meal in livestock diets has led to the exploration of legumes such as faba beans [FBs] (Vicia faba L.). …”
Get full text

Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients by Shengpeng Li, Zhengguo Xu, Hua Diao, An Zhou, Dianji Tu, Sumin Wang, Yunxuan Feng, Xiaojie Feng, Yi Lai, Shiming Yang, Bo Tang

“…Accurate preoperative prediction of the risk of developing hepatic encephalopathy is critical for optimizing the rational clinical application of TIPS. Methods In this study, stool samples from 67 patients were collected preoperatively and 1 month postoperatively and metagenomic sequencing was performed to assess the composition of the gut microbiota. …”
Get full text

The anti-depressive role of the Pei Yuan Kai Yu formula in cerebral small vessel disease based on gut microbiota by Lixuan Yang, Lixuan Yang, Yutian Ao, Yannan Li, Baoan Dai, Junnan Li, Wenzhe Duan, Kaiqiang Dong, Zhenyun Han, Rongjuan Guo

“…BackgroundCerebral small vessel disease (CSVD), characterized by pathological changes in brain vessels, is a common cause of death in the elderly and often accompanied by depression, which significantly affects patients’ quality of life and rehabilitation; understanding its pathogenesis and developing innovative therapies are urgently needed, especially considering the role of the blood - brain barrier impairment and the gut - microbiota - gut - brain axis in this complex condition.MethodsDahl/SS rats were fed a diet containing 8% NaCl and were subjected to chronic unpredictable mild stress (CUMS) stimulation for 4 weeks. …”
Get full text

The Potential of <i>Zanthoxylum acanthopodium</i> DC. as Immunomodulators: Formulation, Activity Testing, and Extract Profiling by Damaris Br. Hutapea, Yasmiwar Susilawati, Muhaimin Muhaimin, Riezki Amalia, Aisyah Tri Mulyani, Anis Yohana Chaerunisaa

“…<b>Background/Objectives</b>: One of the plants found in Indonesian forests that has potential as an herbal medicine is andaliman (<i>Zanthoxylum acanthopodium</i> DC.). …”
Get full text

Single-cell and spatial transcriptome analyses reveal MAZ(+) NPC-like clusters as key role contributing to glioma recurrence and drug resistance by Qiang Gu, Kan Wang, Tingming Lu, Yifei Xiao, Yaqing Wu, Hang Zhou, Kaijia Zhou

“…Abstract Background Temozolomide (TMZ) is an important chemotherapeutic agent for glioma treatment. …”
Get full text

Fecal microbiota transplantation restores gut microbiota diversity in children with active Crohn’s disease: a prospective trial by Biao Zou, Shengxuan Liu, Chen Dong, Hexiao Shen, Yongling Lv, Jiayi He, Xuesong Li, Mengling Ruan, Zhihua Huang, Sainan Shu

“…Abstract Background Clinical data on oral fecal microbiota transplantation (FMT), a promising therapy for Crohn’s disease (CD), are limited. …”
Get full text

The association between plant-based diet indices and the risk of breast cancer: a case-control study by Fateme Souni, Fatemeh Mansouri, Fatemeh Jafari, Reza Sharifi, Sepideh PourvatanDoust, Zainab Shateri, Mehran Nouri, Bahram Rashidkhani

“…Abstract Background Previous studies examining the relationship between plant-based diets and breast cancer (BrC) have provided conflicting evidence. …”
Get full text

Perivascular Lymphocyte Clusters Induced by Gastric Subserous Layer Vaccination Mediate Optimal Immunity against Helicobacter through Facilitating Immune Cell Infiltration and Loca... by Chupeng Hu, Wei Liu, Ningyin Xu, An Huang, Zhiqin Zeng, Shuanghui Luo, Zhenxing Zhang, Menghui Fan, Feng Ye, Tao Xi, Yingying Xing

“…Background. In situ vaccination-induced local inflammatory response resulted in the establishment of a pool of tissue-resident memory T (TRM) cells and new vessels after the resolution of inflammation. …”
Get full text

Modern clinical portrait of ovarian cancer patient in the Novosibirsk region by A. V. Tarkhov, M. A. Goncharov, A. V. Tereschenko, N. Yu. Zvezdina, N. A. Buksel, D. K. Ukolova, L. Yu. Konovalova, D. K. Nikitina, D. V. Morozov, M. S. Selyakova

“…Background. Ovarian cancer is one of the most common malignant neoplasms of the female genital area. …”
Get full text

Identification of anti-fibrotic compounds from Piper longum L via hollow fiber cell fishing and high-performance liquid chromatography with in vivo and in vitro validation by Jie Tian, Nan Zhou, Heng Wang, Wanghui Jing, Guoping Zheng

“…Abstract Background Traditional Chinese medicine (TCM) is an important source of bioactive compounds, hence enjoying a wide application in clinical treatment, while its pharmacodynamic material basis remains difficult to elucidate as it has a complex chemical composition. …”
Get full text