Carbohydrate metabolism, pancreas functional activity and diet in young residents of two ethnic groups in the North by Inessa V. Averyanova

“…The blood insulin level in examined young men was lowered towards the lower limit of the reference range. Against the background of detected hyperglycemic manifestations in young men of two studied groups in Magadan Oblast, their dietary intake was characterized by insufficiency and imbalance in both micronutrient and macronutrient compositions. …”
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Physical activity interventions in adult kidney transplant recipients: an updated systematic review and meta-analysis of randomized controlled trials by Roseanne E. Billany, Nicolette C. Bishop, Ellen M. Castle, Matthew P. M. Graham-Brown, Sharlene A. Greenwood, Courtney J. Lightfoot, Thomas J. Wilkinson

“…Background Kidney transplant recipients (KTRs) exhibit a high prevalence of cardiovascular disease (CVD) and adverse changes in physical fitness and body composition. …”
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Concurrent and predictive validity of nutritional screening tools in hospitalized pediatric patients: Protocol for a single-center, prospective, observational study by Maria Camila Arbeláez Grajales, Dianna Ramírez-Prada, Frank Carrera-Gil

“…Summary: Background and aim: Early identification of nutritional risk is essential in the care of hospitalized children. …”
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Single-cell sequencing combined with spatial transcriptomics reveals the characteristics of follicle-targeted inflammation patterns in primary cicatricial alopecia by Qitao Chen, Yuqian Li, Qilin Zhu, Zhongming Li, Guanghui Shao, Yanjun Liu, Peixuan Jiang, Qiuwei Tao, Lili Shen, Jing Zhu, Linwei Wei, Yanhua Li, Xufeng Du

“…Abstract Background Primary cicatricial alopecia (PCA) causes irreversible hair loss due to immune-mediated hair follicle destruction. …”
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Epigenetic signatures in surrogate tissues are able to assess cancer risk and indicate the efficacy of preventive measures by James E. Barrett, Chiara Maria Herzog, Sepideh Aminzadeh-Gohari, Elisa Redl, Isma Ishaq Parveen, Julia Rothärmel, Julia Tevini, Daniela D. Weber, Luca Catalano, Victoria E. Stefan, Thomas K. Felder, Peter Obrist, Twana Alkasalias, Kristina Gemzell-Danielsson, Roland Lang, Barbara Kofler, Martin Widschwendter

“…Methods Here we utilized medroxyprogesterone acetate and 7,12-dimethylbenzanthracene to induce mammary gland cancers in mice. …”
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Characteristics of cancer mycobiome in patients with acral melanoma by Lin Li, Qi Sun, Rong Huang, Zhengyun Zou, Jiayu Wang, Lianjun Zhao, Donglin Kang, Xinyu Su, Yirong Wu, Ziyao Xie

“…However, their role in acral melanoma (AM) has not been previously explored.Methods We characterized the mycobiome in AM tumor tissues and adjacent non-tumor tissues. …”
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Tackling the primary healthcare workforce crisis: time to talk about health systems and governance—a comparative assessment of nine countries in the WHO European region by Ellen Kuhlmann, Michelle Falkenbach, Monica Georgina Brînzac, Tiago Correia, Maria Panagioti, Bernd Rechel, Anna Sagan, Milena Santric-Milicevic, Marius-Ionuț Ungureanu, Iris Wallenburg, Viola Burau

“…Abstract Background Primary healthcare has emerged as a powerful global concept, but little attention has been directed towards the pivotal role of the healthcare workforce and the diverse institutional setting in which they work. …”
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Single-cell transcriptomic analyses reveal heterogeneity and key subsets associated with survival and response to PD-1 blockade in cervical squamous cell carcinoma by Xia Li, Zhao Zhao, Yanmei Cheng, Jiaqin Yan, Fang Ren, Yanyan Jia, Juanhua Li, Binhui Wang, Junqi Liu, Chenyin Wang, Meimei Gao, Hao Gu, Mingliang Fan, Huirong Shi, Mei Ji, Qitai Zhao

“…Methods In this study, we characterized 50,649 cells obtained from the CSCC for single-cell RNA sequencing and integrated bulk sequencing data from The Cancer Genome Atlas (TCGA) and clinical samples to explore their cell composition, metabolic processes, signaling pathways, specific transcription factors, lineage tracking and response to immunotherapy. …”
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Intermittent supplementation with Akkermansia muciniphila and galactooligosaccharides modulates Alzheimer’s disease progression, gut microbiota, and colon short-chain fatty acid pr... by Arnas Kunevičius, Akshay Kumar Vijaya, Alessandro Atzeni, Jonas Mingaila, Ieva Šimoliūnė, Rapolas Jamontas, Emilija Keževičiūtė, Miguel Gueimonde, Rolandas Meškys, Daiva Baltriukienė, Silvia Arboleya, Aurelijus Burokas

“…BackgroundBidirectional communication and mutual regulation between the gastrointestinal tract and the CNS is facilitated through the gut-brain axis. …”
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An Overview of the Etiopathogenic Mechanisms Involved in the Expression of the Oral Microbiota by Ion Alexandru Popovici, Cristian Ionut Orasanu, Georgeta-Camelia Cozaru, Anita-Cristina Ionescu, Lidia Kajanto, Bogdan Cimpineanu, Anca Chisoi, Adrian Nelutu Mitroi, Ionut Poinareanu, Raluca Ioana Voda, Oana Andreea Ursica, Mihaela Butcaru Pundiche

“…<b>Background/Objectives</b>: The diversity of the oral microbiota exerts its effects in maintaining dental and overall health. …”
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Comprehensive Characterization of Serum Lipids of Dairy Cows: Effects of Negative Energy Balance on Lipid Remodelling by Zhiqian Liu, Wenjiao Wang, Joanne E. Hemsworth, Coralie M. Reich, Carolyn R. Bath, Monique J. Berkhout, Muhammad S. Tahir, Vilnis Ezernieks, Leah C. Marett, Amanda J. Chamberlain, Mike E. Goddard, Simone J. Rochfort

“…Background: The presence and concentration of lipids in serum of dairy cows have significant implications for both animal health and productivity and are potential biomarkers for several common diseases. …”
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The Impact of Obesity on the Association between Parity and Risk of Type 2 Diabetes Mellitus by Yuki Gen, Kyuho Kim, Joonyub Lee, Junyoung Jung, Sang-Hyuk Jung, Hong-Hee Won, Dokyoon Kim, Yun-Sung Jo, Yu-Bae Ahn, Seung-Hyun Ko, Jae-Seung Yun

“…This study aims to explore the complex relationship between parity and T2DM risk, considering additional factors such as obesity, race, and body composition. Methods This prospective cohort study used data from 242,159 women aged 40 to 69 from the UK Biobank, none of whom had T2DM at baseline. …”
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Pre‐clinical enteropathy in healthy soft‐coated wheaten terriers by M. Katherine Tolbert, Jewels Darrow, Louise Grubb, Stuart Fitzgerald, Rebecca Bergee, Josh Price, Marcos Mariano, Michael Hong, Chi‐Hsuan Sung, Tracy Hill, Joerg M. Steiner, Jan S. Suchodolski

“…Abstract Background Soft‐coated wheaten terriers (SCWTs) have a predisposition to the development of protein‐losing enteropathy (PLE). …”
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Self-Assembled Cannabigerol-Based Nanoparticles: Design, Synthesis, and Antiproliferative Activity by Arianna Amenta, Giulia Nordio, Francesco Piazzola, Maria Luisa Di Paolo, Fabio Milani, Martina Giacomini, Andrea Citarella, Umberto Ciriello, Giuseppe Paladino, Sara Pellegrino, Federica Silvestri, Valerio Fasano, Lisa Dalla Via, Daniele Passarella

“…<b>Background/Objectives:</b> Cannabigerol (CBG) is a non-psychoactive phytocannabinoid with significant therapeutic potential, showing emerging applications in drug delivery. …”
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Targeted and Non-Targeted Metabolomic Evaluation of Cerebrospinal Fluid in Early Phase Schizophrenia: A Pilot Study from the Hopkins First Episode Psychosis Project by George E. Jaskiw, Mark E. Obrenovich, Curtis J. Donskey, Farren B. S. Briggs, Sun Sunnie Chung, Anastasiya I. Kalinina, Austin Bolomey, Lindsay N. Hayes, Kun Yang, Robert H. Yolken, Akira Sawa

“…Compared to peripheral compartments, cerebrospinal fluid (CSF) more closely reflects the chemical composition of brain extracellular fluid. Given that brain dysregulation may be more pronounced during the first episode of psychosis (FEP), we hypothesized that metabolomic analysis of CSF from FEP patients could reveal disease-associated biomarkers. (2) Methods: We recruited 15 patients within 24 months of psychosis onset (DSM-4 criteria) and 14 control participants through the Johns Hopkins Schizophrenia Center. …”
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Feasibility and predictive factors on the completion of docetaxel plus S‐1 adjuvant chemotherapy in pathological stage III gastric cancer by Masayoshi Terayama, Manabu Ohashi, Kensei Yamaguchi, Daisuke Takahari, Rie Makuuchi, Masaru Hayami, Satoshi Ida, Koshi Kumagai, Takeshi Sano, Souya Nunobe

“…Abstract Background The standard adjuvant chemotherapy regimen for stage III gastric cancer is docetaxel plus S‐1 (DS) based on the results of the START‐II trials. …”
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Reduced synaptic tagging by complement protein C3 is associated with elevated extracellular matrix in the middle-aged cerebellum of mice by Henning Peter Düsedau, Carla Cangalaya, Stoyan Stoyanov, Alexander Dityatev, Alexander Dityatev, Alexander Dityatev, Ildiko Rita Dunay, Ildiko Rita Dunay, Ildiko Rita Dunay, Ildiko Rita Dunay, Ildiko Rita Dunay

“…BackgroundAging of the brain is associated with cognitive decline and recognized as a major risk factor for the development of neurodegenerative diseases. …”
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The Micro-Structure of the Celiac Ganglia—A Two-Photon Microscopy Study on Parkinson’s Disease by Diana-Theodora Morgos, Lucian-George Eftimie, Horia Nicolae, Remus Iulian Nica, Constantin Stefani, Daniela Miricescu, Radu Hristu, George A. Stanciu, Adrian Tulin, Florin Filipoiu

“…<b>Background/Objectives</b>: This study explores the micro-structure of celiac ganglia using two-photon microscopy (TPM) to highlight histological features in neurodegenerative conditions. …”
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Detection of Respiratory Disease Based on Surface-Enhanced Raman Scattering and Multivariate Analysis of Human Serum by Yulia Khristoforova, Lyudmila Bratchenko, Vitalii Kupaev, Dmitry Senyushkin, Maria Skuratova, Shuang Wang, Petr Lebedev, Ivan Bratchenko

“…<b>Background/Objectives</b>: Chronic obstructive pulmonary disease (COPD) is a significant public health concern, affecting millions of people worldwide. …”
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Development of Ferrero Nutrition Criteria: category-specific, progressive guidelines for product innovation by Federico Canzoneri, Mélanie Charron, Adam Drewnowski, Emanuela Alzari, Marta Biolatti, Emanuela Cavalli, Marco Franci, Stefania Giri, Fritz Maingrette, Maria Malgorzata Maj, Ileana Manera, Ginevra Rosso, Vittoria Russo, Gloria Veneziani, Sebastiano Collino, Enrico Pavesi

“…BackgroundNutrition standards developed for internal use can help assess nutrient density and guide improvements in company product portfolios. …”
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