Ecotoxicological insight of phytochemicals, toxicological informatics, and heavy metal concentration in Tridax procumbens L. in geothermal areas by N.B. Maulydia, R. Idroes, K. Khairan, T.E. Tallei, F. Mohd Fauzi

“…BACKGROUND AND OBJECTIVES: Tridax procumbens L. is a plant that grows abundantly in the Ie-Seu'um geothermal area in Aceh Province, Indonesia. …”
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Status of sleeping habits and its influence on growth and metabolism of children in Beijing: a population-based cross-sectional study by Yiren Chen, Lijun Wu, Zijun Liao, Yiying Huang, Qin Liu, Shaoli Li, Junting Liu, Xinnan Zong, Jun Tai, Fangfang Chen

“…Abstract Background Sleep disturbances are associated with poor health outcomes in children. …”
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Radon Exhalation Rate, Radioactivity Content, and Mineralogy Assessment of Significant Historical and Artistic Interest Construction Materials by Francesco Caridi, Daniele Chiriu, Stefania Da Pelo, Giuliana Faggio, Michele Guida, Giacomo Messina, Maurizio Ponte, Silvestro Antonio Ruffolo, Domenico Majolino, Valentina Venuti

“…In this paper, an investigation focused on assessing the radon exhalation, the natural radioactivity level, and the mineralogy of natural stones of particular historical–artistic interest employed as building materials was carried out. The Closed Chamber Method (CCM) with the Durridge Rad7 apparatus for short-lived radon progeny alpha spectrometry and High Purity Germanium (HPGe) gamma spectrometry were used to determine the radon exhalation rate and specific activities of ²²⁶Ra, ²³²Th, and ⁴⁰K, respectively. …”
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Antibacterial activity of selenium nanoparticles/copper oxide (SeNPs/CuO) nanocomposite against some multi-drug resistant clinical pathogens by Ahmed Morad Asaad, Sara A. Saied, Mohammad M. Torayah, N. I. Abu-Elsaad, Samah Mohammed Awad.

“…Methods The Se-NPs/Cu2O nanocomposite was fabricated using the chemical deposition method. …”
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Microplastic in the gastrointestinal tract of Bombay duck (Harpadon nehereus) in the Patenga Beach of the Bay of Bengal, Bangladesh: occurrence, abundance, and physicochemical feat... by Sabah tuz Zohora, Shahida Arfine Shimul, Saifuddin Rana, Antar Sarkar, Sui Naing Aye Marma Milky, Khing Khing U Marma, Kaji Mohammad Sirajum Monir, Farhan Azim, Tapos Kumar Chakraborty, Sk. Ahmad Al Nahid

“…The color, type, and size were observed with microscopic image analysis software and polymer composition was determined with Fourier transform infrared spectroscopy method. …”
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The impact of low energy availability risk on pre-competition physiological function in Chinese female combat athletes by Yiheng Liang, Yuxuan Li, Yan Chen, Kun Meng, Fanyang Zhou, Yiran Pei, Yong Liu, Junqiang Qiu

“…Background Low energy availability (LEA) can negatively impact athletes’ physiological function and performance. …”
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Dysbiosis of Gut Microbiota Promotes Hepatocellular Carcinoma Progression by Regulating the Immune Response by Nan Zhang, Yusong Gou, Shan Liang, Ning Chen, Yali Liu, Qiushui He, Jing Zhang

“…Background and Aim. Dysbiosis of gut microbiota is important in the development of hepatocellular carcinoma (HCC). …”
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Meat productivity and beef quality of Aberdeen-Angus bulls at different levels of estradiol in blood serum by Zavyalov O.A., Frolov A.N., , Kharlamov A.V., Platonov S.A., Kurilkin Ya.Ya.

“…Animals were divided into three groups according to serum estradiol levels by the percentile method: I Group - up to the 25th percentile; II Group - within the 25th-75th percentile; III Group - above the 75th percentile. …”
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Nutritional, functional, and microbial qualities of legume-based flour blends processed by SMEs in Zambia and Malawi compared to standard Corn-Soy Blend Plus (CSB +): a cross-secti... by Patrick Ndovie, Smith G. Nkhata, Numeri Geresomo, Robert Fungo, Vincent Nyau, Richard Banda, Justice Munthali, Martha Chizule, Nellie Manda

“…Abstract Background Legumes enhance food security in developing countries, necessitating an understanding of their properties. …”
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…Comparison of two oral dipeptidyl peptidase (DPP)-4 inhibitors, sitagliptin and linagliptin, for type 2 diabetes mellitus (T2DM) treatment was used as an example.Design Systematic review with MBMA.Data sources MEDLINE, EMBASE, http://www.ClinicalTrials.gov, Cochrane review of DPP-4 inhibitors for T2DM, sitagliptin trials on Food and Drug Administration website to December 2011 and linagliptin data from the manufacturer.Eligibility criteria for selecting studies Double-blind, randomised controlled clinical trials, ≥12 weeks’ duration, that analysed sitagliptin or linagliptin efficacies as changes in glycated haemoglobin (HbA1c) levels, in adults with T2DM and HbA1c >7%, irrespective of background medication.Model development and application A Bayesian model was fitted (Markov Chain Monte Carlo method). …”
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Application of connectivity map technology in traditional Chinese medicines by ZHANG Xiaofang, KANG Yongbo, SU Junhong, KONG Xiangyang

“…Thus, this genomic approach can be integrated with traditional chromatography-based fingerprinting method for better understanding of TCMs. Furthermore, it is important to establish CMap technology as the core platform for TCM research, including discovery of new TCMs and exploration of the new application of TCMs.…”
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Thrombolytic and Anticoagulant Therapy for Pulmonary Embolism with High and Intermendiate Risk of Early Death. Part 3. An Effect on Pulmonary Perfusion with High and Intermediate R... by O. V. Nikitina, I. P. Mikhailov, N. Y. Kudryashova, E. V. Migunova, A. G. Dorfman, V. I. Avfukov

“…Background The advantage of thrombolytic therapy (TLT) over anticoagulant therapy(ACT) in patients with a high risk of early death (hemodynamic disorders) in acute pulmonary embolism is considered proven. …”
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A Characterisation and Profiling of District Health Indicators in Zimbabwe: An Application of Principal Component Analysis in a Data Limited Setting by Shepherd Shamu, Simbarashe Rusakaniko, Charles Hongoro

“…# Background The Ministry of Health and Child Care, Zimbabwe does not have a method for prioritization and equitable allocation of its share of the national health budget and other resources in the sector. …”
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Acute care of aneurysmal subarachnoid hemorrhage: practical consensus statement from a multidisciplinary group of German-speaking neurointensivists and neuroradiologists on behalf... by Rainer Kollmar, Hagen B. Huttner, Yigit Ozpeynirci, Christian Herweh, Jochen A. Sembill, Stefan Gerner, Michael Bender, Patrick Schramm, Ingo Schirotzek, Lisa Maeder, Anisa Myftiu, Marius Hartmann, Juergen Konczalla, Karsten Geletneky, Rainer Kram, Raimund Helbok, Joji B. Kuramatsu, Martin Welte, Amr Abdulazim, Emanuela Keller, Ferdinand Bohmann, Wolf-Rüdiger Schäbitz

“…Conclusion This practical consensus statement provides a standardized approach to aSAH management, balancing guideline-based evidence with expert consensus to address clinical uncertainties. Due to the used methods and composition of the group, the results should be considered as a multi-institutional protocol of an experienced neurointensivist group, but certainly not as evidence based-guidelines. …”
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Comparative analysis of corpus callosum lipidome and transcriptome in schizophrenia and healthy brain by Maria S. Osetrova, Olga I. Efimova, Marina D. Zavolskova, Elena A. Stekolschikova, Gleb N. Vladimirov, Dmitry A. Senko, Tatiana A. Zhuravleva, Anna Y. Morozova, Yana A. Zorkina, Denis S. Andreyuk, George P. Kostyuk, Evgeniy N. Nikolaev, Philipp E. Khaitovich

“…BACKGROUND: Functional and structural studies of the brain highlight the importance of white matter alterations in schizophrenia. …”
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Key considerations based on pharmacokinetic/pharmacodynamic in the design of antibody-drug conjugates by Yangyang Gao, Yuwei Xia, Yixin Chen, Shiqi Zhou, Yingying Fang, Jieru Yu, Leyin Zhang, Leyin Zhang, Leitao Sun, Leitao Sun, Leitao Sun

“…However, complexity of its structural composition poses a greater difficulty for drug design studies.ObjectivesPharmacokinetic/pharmacodynamic (PK/PD) based consideration of ADCs has increasingly become a hot research topic for optimal drug design in recent years, providing possible ideas for obtaining ADCs with desirable properties.MethodsFrom the assessment of the ADC action process based on PK/PD, we introduce the main research strategies of ADCs. …”
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Microbial community profiling for forensic drowning diagnosis across locations and submersion times by Qin Su, Xiaofeng Zhang, Xiaohui Chen, Zhonghao Yu, Weibin Wu, Qingqing Xiang, Chengliang Yang, Jian Zhao, Ling Chen, Quyi Xu, Chao Liu

“…While traditional methods such as diatom analysis have limitations in decomposed remains, microbial community profiling offers a promising alternative. …”
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Saliva Proteome, Metabolome and Microbiome Signatures for Detection of Alzheimer’s Disease by Maxime François, Dana Pascovici, Yanan Wang, Toan Vu, Jian-Wei Liu, David Beale, Maryam Hor, Jane Hecker, Jeff Faunt, John Maddison, Sally Johns, Wayne Leifert

“…<b>Background:</b> As the burden of Alzheimer’s disease (AD) escalates with an ageing population, the demand for early and accessible diagnostic methods becomes increasingly urgent. …”
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Mechanisms of Acetate in Alleviating SETDB1-Linked Neuroinflammation and Cognitive Impairment in a Mouse Model of OSA by Zhao Z, Xiang L, Hong JS, Wang Y, Feng J

“…We aimed to investigate roles of acetate (ACE) and SET domain bifurcated histone lysine methyltransferase 1 (SETDB1) in neuroinflammation of OSA.Methods: After C57BL/6J mice were exposed to OSA-associated intermittent hypoxia (IH) or normoxia for four weeks, the composition of the gut microbiota (GM) and the levels of serum short-chain fatty acids (SCFAs) were measured by 16S rRNA and GC-MS methods, respectively. …”
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Bioinformatics analysis of ferroptosis-related biomarkers and potential drug predictions in doxorubicin-induced cardiotoxicity by Jian Yu, Jian Yu, Jiangtao Wang, Xinya Liu, Xinya Liu, Cancan Wang, Cancan Wang, Li Wu, Yuanming Zhang, Yuanming Zhang

“…BackgroundDoxorubicin-induced cardiotoxicity (DIC) significantly impacts the survival and prognosis of cancer patients. …”
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