Effect of chemoradiotherapy on the dynamics of circulating lymphocyte subsets in patients with non-metastatic nasopharyngeal carcinoma by Lilan Yi, Lilan Yi, Yinfang Gu, Yinfang Gu, Longhua Guo, Longhua Guo, Xiaofang Zou, Xiaofang Zou, Guowu Wu, Guowu Wu

“…BackgroundChemoradiotherapy (CRT) is the primary and most effective treatment for non-metastatic nasopharyngeal carcinoma (NPC), exerting antitumor effects by modulating immune cells. …”
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CD8+ T Cell-Derived Perforin Exacerbates Dysbiosis and Inflammatory Bowel Disease via β-Hydroxybutyrate Suppression in Mouse Colonic Epithelium by Huang S, Pan L, Li M, Pang S, Tian Y, Shi W, Zong Y, Zhang D, Tian D

“…However, the exact mechanisms remain unclear.Methods: We applied a DSS-induced colitis model in wild-type and perforin-deficient (Prf1−/−) mice. …”
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Single-cell transcriptomic analysis reveals prognosis-related stromal signatures that potentiate stratification of patients with extrahepatic cholangiocarcinoma by Chen Ni, Rulin Hua, Yuanyuan Yang, Jialu Liang, Wentao Liu, Linlin Wang, Xiaohan Yao, Anqi Li, Long Yu, Ruo Feng, Dekang Lv, Zhihai Qin, Wenlong Zhai

“…Abstract Background Extrahepatic cholangiocarcinoma (eCCA) is a rare but refractory cancer with dense desmoplasia. …”
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Myeloid TGF-β signaling shapes liver macrophage heterogeneity and metabolic liver disease pathogenesis by Ziyi Meng, Xiaoxue Qiu, Zhimin Chen, Yu-tung Lee, Linkang Zhou, You Lu, Tongyu Liu, Siming Li, Benjamin Levi, Katherine A. Gallagher, Jiandie D. Lin

“…Background & Aims: Cellular heterogeneity of innate immune cells, such as macrophages, in the liver is a hallmark of metabolic dysfunction-associated steatohepatitis (MASH) pathogenesis. …”
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Consistent sleep onset and maintenance of body weight after weight loss: An analysis of data from the NoHoW trial. by Sofus C Larsen, Graham Horgan, Marie-Louise K Mikkelsen, Antonio L Palmeira, Sarah Scott, Cristiana Duarte, Inês Santos, Jorge Encantado, Ruairi O'Driscoll, Jake Turicchi, Joanna Michalowska, R James Stubbs, Berit L Heitmann

“…<h4>Background</h4>Several studies have suggested that reduced sleep duration and quality are associated with an increased risk of obesity and related metabolic disorders, but the role of sleep in long-term weight loss maintenance (WLM) has not been thoroughly explored using prospective data.…”
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Distribution characteristics of bacterial communities in central air-conditioning ventilation systems of a Grade 3A hospital in Shanghai based on 16S rRNA sequencing by Jun NI, Haiyun ZHANG, Jian CHEN, Lijun ZHANG, Yongping LIU, Xiaojing LI, Yiming ZHENG, Liping ZHANG

“…BackgroundA diverse cohort of patients and susceptible individuals congregate in healthcare facilities, where exposure to pathogenic microorganisms associated with respiratory infectious diseases constitutes a significant risk factor for cross-infection. …”
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Short‐chain fatty acids enhance muscle mass and function through the activation of mTOR signalling pathways in sarcopenic mice by Chaoran Liu, Pui Yan Wong, Qianjin Wang, Hei Yuet Wong, Tao Huang, Can Cui, Ning Zhang, Wing Hoi Cheung, Ronald Man Yeung Wong

“…Abstract Background Sarcopenia is a prevalent muscle disorder in old people leading to higher fracture rate, mortality, and other adverse clinical outcomes. …”
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Associations between Hypertriglyceridemia and Circulating Neutrophil Subpopulation in Patients with Dyslipidemia by Vadim Genkel, Ilya Dolgushin, Irina Baturina, Albina Savochkina, Alla Kuznetsova, Lubov Pykhova, Igor Shaposhnik

“…Methods. Ninety-one patients with dyslipidemia, including 22 (24.2%) patients with HTG, were enrolled in the study. …”
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The Role of Ultrasound as a Predictor of Malignancy in Indeterminate Thyroid Nodules—A Multicenter Study by Reem J. Al Argan, Dania M. Alkhafaji, Feras M. Almajid, Njoud K. Alkhaldi, Zahra A. Al Ghareeb, Moutaz F. Osman, Manal A. Hasan, Safi G. Alqatari, Abrar J. Alwaheed, Fatima E. Ismaeel, Reem S. AlSulaiman

“…<i>Background and Objectives:</i> Indeterminate thyroid nodules (Bethesda III and IV) are a common clinical entity that present a diagnostic challenge due to their intermediate risk of malignancy. …”
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Medium wavelength infrared HgCdTe discrete photodetectors by Z. F. Tsybrii, K. V. Andreeva, M. V. Apatska, S. G. Bunchuk, M. V. Vuichyk, O. G. Golenkov, N. V. Dmytruk, V. V. Zabudsky, I. O. Lysiuk, K. V. Svezhentsova, M. I. Smolii, F. F. Sizov

“…FTIR transmission spectra were measured to evaluate samples quality and find the composition of x of Hg1–xCdxTe epitaxial layers grown by liquid phase epitaxy method. …”
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Construction of research feedback experimental teaching mode for medical undergraduate students and comparative study with traditional experimental teaching mode by Chenggui Miao, Yurong Huang, Qiangjun Duan, Yanmei Mao, Jiaqing Chen, Yanping Li, Aixin Xia, Yinqiu Song, Bing Wang

“…There was no difference in the population composition and experimental technical background between the two groups of students, which did not interfere with the statistical results of this study. …”
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Treatment with combined exercise in patients with resistant major depression (TRACE-RMD): study protocol for a randomised controlled trial by Nagore Iriarte-Yoller, José Etxaniz-Oses, Cristobal Pavón-Navajas, Mikel Tous-Espelosin, Pedro M. Sánchez-Gómez, Sara Maldonado-Martín, Ana B. Yoller-Elburgo, Edorta Elizagarate-Zabala

“…Abstract Background Around 40% of people with major depressive disorder (MDD) experience moderate remission, with the remainder meeting the criteria for resistant major depression (RMD). …”
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Bioequivalence Study of Ibuprofen and Diphenhydramine Hydrochloride mini liquid-filled capsules: A Size Reduction Alternative by David J. Wyatt, Mako Araga, Natali McCloskey, Richard Petruschke, Marianna Armogida, MD

“…Background: Advil PM Liqui-Gels are widely used to improve the quality of life for individuals experiencing sleep disturbances due to pain. …”
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Enhancing Holstein steers growth performance: oregano essential oil’s impact on rumen development, functionality and microorganism by Yongliang Huang, Siyu Cheng, Jinping Shi, Pengjia He, Yue Ma, Ruixin Yang, Xu Zhang, Yongzhi Cao, Zhaomin Lei

“…Abstract Background Dietary supplementation with oregano essential oil (OEO), a natural plant extracts, is an effective and acceptable method to improve growth, beef quantity and quality, but the undergoing mechanism in rumen has not yet been reported in Holstein steers. …”
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A prolonged hiatus in postmenopausal HRT, does not nullify the therapy's positive impact on ageing related sarcopenia. by Gladys L Onambélé-Pearson, David J Tomlinson, Christopher I Morse, Hans Degens

“…<h4>Method and findings</h4>In 61 untrained women (18-78yrs) stratified as pre-menopausal, post-menopausal without (No_HRT) and post-menopausal with (Used_HRT) HRT history, body composition, physical activity, serum E2 and T3 were assessed by dual energy x-ray absorptiometry, Baecke questionnaire and ELISA. …”
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The Impact of Physical Activity on Metabolic Health and Cognitive Function in Postmenopausal Women: A Cross-Sectional Study by Kinga Mruczyk, Rafał W. Wójciak, Marta Molska, Ewa Śliwicka, Tomasz Podgórski, Aleksandra Skoczek-Rubińska, Anna Borowiecka, Angelika Cisek-Woźniak

“…<b>Method</b>: A total of 72 generally healthy women aged 55–73 from western Poland participated in the study. …”
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In Vivo Evaluation of the Analgesic and Anti-Inflammatory Activity of <i>Thymus numidicus</i> Essential Oil by Ouardia Chaouchi, Velislava Todorova, Stanislava Ivanova, Elizabet Dzhambazova, Farida Fernane, Nacira Daoudi Zerrouki, Lyudmil Peychev, Kremena Saracheva, Michaela Shishmanova-Doseva, Zhivko Peychev

“…This study aimed to compare the chemical composition of essential oils (EOs) extracted from leaves and flowers using the gas chromatography–mass spectrometry method, as well as to investigate its analgesic and anti-inflammatory activities. …”
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Detection of structural variants linked to mutton flavor and odor in two closely related black goat breeds by Lingle Chang, Xi Niu, Shihui Huang, Derong Song, Xueqin Ran, Jiafu Wang

“…Abstract Background Mutton quality is closely related to genetic variants and gene expression alterations during growth and development, resulting in differences in nutritional values, flavor, and odor. …”
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Borassus aethiopum-Fortified Bread Reduces Metabolic Risk Factors among Cardiovascular Disease Outpatients at 37 Military Hospital, Accra: A Pilot Study by Charles Apprey, Marian Peprah, Reginald Adjetey Annan, Marina A. Tandoh, Odeafo Asamoah-Boakye

“…Background. Dyslipidemia and hypertension are the leading causes of morbidity and mortality in patients with cardiovascular diseases (CVDs). …”
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Suppress or Not to Suppress … CRAFT It: A Targeted Metabolomics Case Study Extracting Essential Biomarker Signals Directly from the Full ¹H NMR Spectra of Horse Serum Sa... by James Chen, Ayelet Yablon, Christina Metaxas, Matheus Guedin, Joseph Hu, Kenith Conover, Merrill Simpson, Sarah L. Ralston, Krish Krishnamurthy, István Pelczer

“…<b>Background</b>: There are a few very specific inflammation biomarkers in blood, namely lipoprotein NMe⁺ signals of protein clusters (GlycA and GlycB) and a composite resonance of phospholipids (SPC). …”
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