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Association of hyperactivated transposon expression with exacerbated immune activation in systemic lupus erythematosus
Published 2024-10-01“…Our study aimed to examine the relationship between TE expression and SLE pathogenesis. Methods We analyzed whole blood RNA-seq datasets from 198 SLE patients and 84 healthy controls. …”
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2462
Gut Microbiota in Different Treatment Response Types of Crohn’s Disease Patients Treated with Biologics over a Long Disease Course
Published 2025-03-01“…<b>Background and Aims:</b> Crohn’s disease (CD) is a chronic inflammatory bowel disease (IBD) with a globally increasing prevalence, partially driven by alterations in gut microbiota. …”
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2463
Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases
Published 2025-01-01“…BackgroundFibrotic skin disease represents a major global healthcare burden, characterized by fibroblast hyperproliferation and excessive accumulation of extracellular matrix components. …”
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2464
Heat-moisture-treated rice improves oral glucose tolerance by modulating serum and fecal metabolites in mice
Published 2025-07-01“…Background/objectiveHeat-moisture treatment (HMT) can increase the composition of resistant starch and reduce the glycemic index in rice. …”
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2465
First molecular evidence of Leishmania parasites in sand flies (Diptera: Phlebotominae) from Slovenia
Published 2025-08-01“…Abstract Background Sand flies (Diptera: Phlebotominae) are vectors of Leishmania spp., protozoan parasites that cause leishmaniasis, a zoonosis endemic in the Mediterranean region. …”
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2466
Using iDNA to determine impacts of Amazonian deforestation on Leishmania hosts, vectors, and their interactions.
Published 2025-03-01“…Strong data informing this debate are sparse because it is challenging to establish direct links between hosts, vectors, and pathogens. However, molecular methods using invertebrate-derived DNA (iDNA) can now measure species composition and interactions from vector samples at landscape scales, which has the potential to improve mechanistic understanding of the effects of land-use change on zoonotic disease risk.…”
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2467
Alterations in gut microbiota of hyperthyroidism rats and the therapeutic effects of Radix Scrophulariae: A study based on fecal metabolomics and 16S rRNA gene sequencing analysis
Published 2025-03-01“…Methods: Hyperthyroid rats were treated with Radix Scrophulariae. …”
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2468
Development and Preclinical Evaluation of a Lyophilized Vaccine Against Equine Herpesvirus Type 4 (EHV-4)
Published 2025-05-01“…Background/Objectives: Equine rhinopneumonia, caused by equine herpesvirus types 1 and 4 (EHV-1 and EHV-4), continues to be a significant health and economic concern in the global equine industry, particularly in Kazakhstan. …”
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2469
Effects of Schistosoma haematobium infection and treatment on the systemic and mucosal immune phenotype, gene expression and microbiome: A systematic review.
Published 2024-09-01“…<h4>Background</h4>Urogenital schistosomiasis caused by Schistosoma haematobium affects approximately 110 million people globally, with the majority of cases in low- and middle-income countries. …”
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2470
Color stability of clear aligners exposed to various beverages: an in vitro study
Published 2025-07-01“…Abstract Background Staining clear aligners from beverages commonly occurs and can affect a patient’s self-esteem and confidence in social interactions. …”
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2471
Therapeutic Adherence in Hypertensive Patients of the Guanabacoa Julio Antonio Mella University Polyclinic
Published 2022-03-01“…<strong>Background:</strong> low adherence to pharmacological treatment is considered a Public Health problem. …”
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2472
Genetic potential of quality in spring bread wheat cultivars bred at Kurgan agricultural research institute
Published 2019-06-01“…Background. For the Trans-Urals, characterized by unstable climate over the years (alternating droughty and excessively moist years, recurrences of colds in spring, possibility of early frosts, etc.), grain quality is a prioritized genetic trait in spring bread wheat cultivars. …”
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2473
Antimicrobial Efficacy of Five Wound Irrigation Solutions in the Biofilm Microenvironment In Vitro and Ex Vivo
Published 2025-01-01“…<b>Background/Objectives:</b> Periprosthetic joint infections (PJI) are difficult to treat due to biofilm formation on implant surfaces and the surrounding tissue, often requiring removal or exchange of prostheses along with long-lasting antibiotic treatment. …”
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2474
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2475
Abnormality in field physical test predicts a reduced quadriceps strength in patients with hip- or knee-osteoarthritis. A prospective observational study.
Published 2024-01-01“…<h4>Background</h4>In osteoarthritis quadriceps strength is an important outcome to assess exercise capacity and recovery after arthroplasty. …”
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2476
Liposomal and Nanostructured Lipid Nanoformulations of a Pentacyclic Triterpenoid Birch Bark Extract: Structural Characterization and In Vitro Effects on Melanoma B16-F10 and Walke...
Published 2024-12-01“…<b>Background/Objectives</b>: Pentacyclic triterpenoids are increasingly studied as anticancer agents with many advantages compared to synthetic chemotherapeutics. …”
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2477
ASSESSMENT OF THE IMPACT OF VANILLIN AND QUERCETIN ON THE DEGREE OF FEED DIGESTABILITY AND THE RUMEN MICROBIOME OF CATTLE
Published 2024-12-01“…Background. There are various ways to modulate rumen microbial diversity of ruminants, one of which is the use of feed additives. …”
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2478
Correlation between MDA Level and Chitotriosidase-1 Activity in Seminal Fluid of Iraqi Infertile Males
Published 2024-12-01“… Background: Male infertility is a multifactorial condition influenced by various physiological and biochemical factors. …”
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2479
New breeding material of winter rapeseed (<i>Brassica napus</i> L.) with increased yield and high oleic acid content in seed oil
Published 2025-07-01“…Background. The development of rapeseed cultivars with higher oleic acid content in seed oil is an important goal of rapeseed breeding programs worldwide, but the yield of high-oleic lines and cultivars is lower than that of traditional high-yielding cultivars and hybrids. …”
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2480
Collecting at-Home Biometric Measures for Longitudinal Research From the i3C: Feasibility and Acceptability Study
Published 2025-06-01“…ObjectiveIn this study, we assessed the feasibility of a “Virtual Home Clinic” within the context of long-term epidemiologic studies. MethodsParticipants from 3 study cohorts were recruited. …”
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