Saccharomyces boulardii (CNCM I-745) improves intestinal damage in sepsis by remodeling intestinal flora structure by Hui-Ying Liu, Yao Li, Yi-Lu Lin, Yu-Jia Tang, Jin-Da Zhao, Jia Xu, Kuo Wang, Ying-Fei Zhi, Yan Zhang, Jia-Le Deng, Kai Kang, Ying Chen, Yang Gao

“…BackgroundSepsis is one of the leading causes of mortality among intensive care unit (ICU) patients. …”
Get full text

Dietary amino acids intake and all-cause and cause-specific mortality: results from the Golestan Cohort Study by Asieh Mansour, Sayed Mahmoud Sajjadi-Jazi, Maryam Mirahmad, Pooria Asili, Maryam Sharafkhah, Sahar Masoudi, Hossein Poustchi, Akram Pourshams, Maryam Hashemian, Azita Hekmatdoost, Reza Malekzadeh

“…Abstract Background Less is known whether the amino acid composition of dietary protein sources effects on long-term health outcomes. …”
Get full text

Effects of different grain types on nutrient apparent digestibility, glycemic responses, and fecal VFA content in weaned foals by Xinxin Huang, Qian Li, Xuanyue Li, Chao Li, Jiahao Li, Linjiao He, Hongxin Jing, Fan Yang, Xiaobin Li

“…This study examines the impact of diets incorporating steam-flaked grains (corn, oats, and barley) on apparent nutrient digestibility, glycemic response, and fecal volatile fatty acid (VFA) composition in the weaned Kazakh foals. Methods Eighteen male Kazakh foals, weaned at 5 months, were randomly assigned to three groups (n = 6 per group) based on grain type: corn group (CG), oats group (OG), and barley group (BG). …”
Get full text

Association of PM2.5 and its elemental components with plasma metabolome in healthy older adults: Evidence from epidemiological and experimental studies by Quan Zhou, Liangping Chen, Chenzhou He, Xiaoying Liu, Wenli Wang, Shuling Kang, Yu Jiang, Jianjun Xiang, Xiaoyang Zhang, Chuancheng Wu

“…Background: Previous studies have found that exposure to fine particulate matter (PM2.5) is associated with metabolic alterations, but the specific effects of its composition on metabolic changes remain unclear. …”
Get full text

Single-cell transcriptomics link gene expression signatures to clinicopathological features of gonadotroph and lactotroph PitNET by T. Elise Potthoff, Carolin Walter, Daniela Jeising, Daniel Münter, Archana Verma, Eric Suero Molina, Walter Stummer, Martin Dugas, Wolfgang Hartmann, Matthias Dottermusch, Lea Altendorf, Ulrich Schüller, Sophia Scheuermann, Christian Seitz, Thomas K. Albert, Kornelius Kerl

“…Abstract Background Pituitary neuroendocrine tumors (PitNET) are among the most common intracranial tumors. …”
Get full text

Western Experience of Hepatolithiasis: Clinical Insights from a Case Series in a Tertiary Center by Natale Calomino, Ludovico Carbone, Engjell Kelmendi, Stefania Angela Piccioni, Gianmario Edoardo Poto, Giulio Bagnacci, Luca Resca, Annalisa Guarracino, Sergio Tripodi, Bina Barbato, Stefano Brillanti, Franco Roviello, Gian Luigi Adani, Daniele Marrelli

“…<i>Background and Objectives</i>: Hepatolithiasis (HL), or intrahepatic bile duct stone disease, shows regional variation and is a rare condition in Western countries. …”
Get full text

The effect of the administration form of antibiotic therapy on the gut microbiome in patients with infected diabetic foot ulcers - DFIATIM trial by Chahrazed Mekadim, Jakub Mrazek, Kateřina Olša Fliegerová, Hana Sechovcová, Tiziana Maria Mahayri, Radka Jarošíková, Jitka Husáková, Veronika Wosková, Petr Tůma, Jan Polák, Dominika Sojáková, Andrea Němcová, Michal Dubský, Vladimíra Fejfarová

“…Abstract Background Diabetic foot infections (DFIs) contribute to the global disability burden. …”
Get full text

Analysis of water parameters in experimental ponds of PRJSC “Khmelnytskrybhosp” as a prerequisite for the creation of replacement and brood stocks of Antoniny-Zozulenets carps (Cyp... by V. Oborskyi, N. Mykhailenko, T. Bersan, H. Kurinenko, L. Drahan

“…Chemical analysis of pond water was performed in a certified ecological research laboratory of the Institute of Fisheries of the NAAS in accordance with generally accepted methods in hydrochemistry. Studies of the chemical composition of water in the experimental ponds were carried out once a month for the purpose of background control throughout the entire cultivation period. …”
Get full text

The Effect of the Mediterranean Diet–Integrated Gamified Home-Based Cognitive-Nutritional (GAHOCON) Training Programme for Older People With Cognitive Frailty: Pilot Randomized Con... by Rick Yiu Cho Kwan, Queenie Pui Sze Law, Jenny Tsun Yee Tsang, Siu Hin Lam, Kam To Wang, Olive Shuk Kan Sin, Daphne Sze Ki Cheung

“…ObjectiveThis study aims to examine the feasibility and preliminary effects of Gamified Home-Based Cognitive-Nutritional (GAHOCON) on older adults with cognitive frailty, focusing on Mediterranean diet knowledge, adherence to the Mediterranean diet, cognitive function, physical frailty, grip strength, walking speed, memory, and body composition. MethodsThis study applied a 2-center, assessor-blinded, 2-parallel-group, noninferiority, randomized controlled trial design. …”
Get full text

High-resolution analysis of the treated coeliac disease microbiome reveals strain-level variation by Jelle Slager, Hanna L. Simpson, Ranko Gacesa, Lianmin Chen, Ineke L. Tan, Jody Gelderloos, Astrid Maatman, Cisca Wijmenga, Alexandra Zhernakova, Jingyuan Fu, Rinse K. Weersma, Gieneke Gonera, Iris H. Jonkers, Sebo Withoff

“…While recent data show that alterations in gut microbiome composition could play an important role, many current studies are constrained by small sample sizes and limited resolution.Methods To address these limitations, we analyzed fecal gut microbiota from two Dutch cohorts, CeDNN (128 treated CeD patients (tCeD), 106 controls) and the Lifelines Dutch Microbiome Project (24 self-reported tCeD, 654 controls), using shotgun metagenomic sequencing. …”
Get full text

Optimizing therapeutic outcomes of immune checkpoint blockade by a microbial tryptophan metabolite by Giorgia Renga, Emilia Nunzi, Marilena Pariano, Matteo Puccetti, Marina Maria Bellet, Giuseppe Pieraccini, Fiorella D’Onofrio, Ilaria Santarelli, Claudia Stincardini, Franco Aversa, Francesca Riuzzi, Cinzia Antognelli, Marco Gargaro, Oxana Bereshchenko, Maurizio Ricci, Stefano Giovagnoli, Luigina Romani, Claudio Costantini

“…Background Despite the great success, the therapeutic benefits of immune checkpoint inhibitors (ICIs) in cancer immunotherapy are limited by either various resistance mechanisms or ICI-associated toxic effects including gastrointestinal toxicity. …”
Get full text

KRM-II-81, a β3-Preferring GABA_A Receptor Potentiator, Blocks Handling-Induced Seizures in Theiler’s Murine Encephalomyelitis Virus-Infected Mice by Dishary Sharmin, Kamal P. Pandey, Lalit K. Golani, Sepideh Rezvanian, Md Yeunus Mian, Janet L. Fisher, Arnold Lippa, James M. Cook, Daniel P. Radin, Jodi L. Smith, Jeffrey M. Witkin, Hana Shafique, Rok Cerne

“…<b>Methods:</b> In the present study, KRM-II-81 was studied against handling-induced seizures in Theiler’s murine encephalomyelitis virus (TMEV)-infected mice. …”
Get full text

Combined effects of aerobic exercise with ketogenic mediterranean and hypocaloric balanced diets on adolescents with polycystic ovarian syndrome by Reham Hamoda, Nada Elkady, Afaf Botla, Amir Gabr, Efrem Kentiba, Shaimaa Hamed

“…Background and purpose Polycystic ovarian syndrome (PCOS), the most common endocrine disorder in women of reproductive age, is characterized by hyperandrogenism, chronic anovulation, and insulin resistance (IR), with obesity and low-grade inflammation exacerbating its metabolic sequelae. …”
Get full text

Breast milk: its components and special effects on newborns and infants by T. Voroncova, T. Konyk, M. Trokhymenko, Y. Mudryk

“… Background. Breastfeeding is the gold standard of infant nutrition, ensuring optimal growth, development, and formation of the immune system during the first six months of life. …”
Get full text

Efficacy of a Digital Educational Intervention for Patients With Type 2 Diabetes Mellitus: Multicenter, Randomized, Prospective, 6-Month Follow-Up Study by Irene Caballero Mateos, Cristóbal Morales Portillo, María Lainez López, Ángel Vilches-Arenas

“… BackgroundAdherence to therapies and metabolic control among patients with type 2 diabetes mellitus (T2DM) remain challenging. …”
Get full text

Dietary Patterns of Serbian Adults 10–74 Years Old: Serbian National Food Consumption Survey Following EU Menu Methodology by Jelena Milešević, Milica Zeković, Ivana Šarac, Marija Knez, Irena Krga, Vuk Stevanović, Mirjana Gurinović

“…Background and objectives: Increasing rates of adult overweight (60.7% population) and diet-related cardiovascular diseases (52% population) in Serbia alarmingly call for a change in dietary patterns. …”
Get full text

Three-dimensional partitioning and quantification of orthodontic root resorption via automatic root extraction from cone-beam computed tomography by Jing Huang, Mengjie Wang, Xuan Tang, Leilei Zheng, Chongshi Yang

“…Methods Thirty-six patients with malocclusion were included and divided into two groups. …”
Get full text

Integrating DNA and RNA sequencing for enhanced pathogen detection in respiratory infections by Dejian Gu, Jie Liu, Jiaping Wang, Yuting Yi, Yuxing Chu, Rui Gao, Hao Liu, Jun She, Binghuai Lu

“…Bioinformatics simulation confirmed the method’s high specificity and robustness. In 281 patients of clinical validation cohort, tNGS exhibited a sensitivity of 97.73% and specificity of 75.41% compared to the composite reference standard, which notably surpasses those of culture-based and conventional microbiological methods (CMT). …”
Get full text

Comparison and application of depression screening tools for adolescents: scale selection and clinical practice by Xinyu Li, Wei Jin, Lu Han, Xingyu Chen, Lihong Li

“…Additionally, 13 original development studies of the included scales were further reviewed to extract and analyze information on their developmental background, structural dimensions, item composition, and applicability. …”
Get full text

The Linguistic Heritage of the Bangladeshi ‘New Communities’ of Venice (Italy) by Ferro, Giulia

“… This paper presents the initial findings of a sociolinguistic study conducted using ethnographic methods on the Bangladeshi community of Venice (Italy). …”
Get full text