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Prenatal Bisphenol B Exposure Induces Adult Male Offspring Reproductive Dysfunction via ERα Inhibition-Triggered MHC I-Mediated Testicular Immunological Responses
Published 2025-05-01“…As an emerging endocrine-disrupting agent and structural analog of bisphenol A (BPA), bisphenol B (BPB) raises significant concerns due to its potential to induce male reproductive toxicity. …”
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α-Synuclein pathology and mitochondrial dysfunction: Toxic partners in Parkinson's disease
Published 2025-06-01Get full text
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Active Vitamin D Ameliorates Arsenite-Induced Thyroid Dysfunction in Sprague–Dawley Rats by Inhibiting the Toll-like Receptor 4/NF-KappaB-Mediated Inflammatory Response
Published 2024-12-01“…Supplementation with TAK-242 (a TLR4 inhibitor) and VD effectively inhibits the activation of the TLR4/NF-κB signaling pathway in rat thyroid tissue exposed to NaAsO<sub>2</sub>, thereby reducing the inflammatory damage and dysfunction caused by arsenic exposure. …”
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ENDOTHELIAL SYSTEM OF MOTHER AND FETUS DURING THE FIRST TRIMESTER OF PREGNANCY
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The regulatory functions of G protein-coupled receptors signaling pathways in B cell differentiation and development contributing to autoimmune diseases
Published 2025-04-01“…Ligands and functions of GPCR—chemokine receptors including CXCR3, CXCR4, CXCR5 and CCR7, lipid receptors including S1PR1-5, cannabinoid receptor CB2 as well as orphan GPCR including GPR132, GPR183, GPR174, and P2RY8 in B cell differentiation and development, will be elaborated in this review. …”
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Ghrelin/GHSR Axis Induced M2 Macrophage and Alleviated Intestinal Barrier Dysfunction in a Sepsis Rat Model by Inactivating E2F1/NF-κB Signaling
Published 2023-01-01“…The activation and regulation of the immune system play an essential role in the development of sepsis. Our previous studies have shown that ghrelin ameliorates intestinal dysfunction in sepsis. …”
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Phthalates in face masks and their effects on cellular energetics in human bronchial epithelial cells
Published 2025-03-01“…The observed effects at the mitochondrial level varied according to the specific phthalates that were tested. The major dysfunctions were identified following exposure to DEHP, which exerted inhibitory effects on the basal and maximal oxygen consumption rate of BEAS-2B cells, as well as an alteration in oxidative phosphorylation and a reduction in the ATP/ADP ratio. …”
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Involvement of Oxidative Stress in Mitochondrial Abnormalities During the Development of Heart Disease
Published 2025-05-01“…<b>Background:</b> Several mitochondrial abnormalities such as defective energy production, depletion of energy stores, Ca<sup>2+</sup> accumulation, generation of reactive oxygen species, and impaired intracellular signaling are associated with cardiac dysfunction during the development of different heart diseases. …”
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Cerebral dysfunction in patients with acute myocardial infarction
Published 2023-12-01Get full text
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Dysfunction of the meibomian glands in patients with diabetes mellitus
Published 2022-05-01Get full text
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The pharmacological management of erectile dysfunction – Update 2016
Published 2016-08-01Get full text
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Endothelial dysfunction in patients with different obesity phenotypes
Published 2024-09-01Get full text
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