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  1. 421

    Aging Lung: Molecular Drivers and Impact on Respiratory Diseases—A Narrative Clinical Review by Paweł Górski, Adam J. Białas, Wojciech J. Piotrowski

    Published 2024-12-01
    “…This narrative clinical review explores the molecular and biochemical hallmarks of aging, such as oxidative stress, telomere attrition, genomic instability, epigenetic modifications, proteostasis loss, and impaired macroautophagy, and their roles in lung senescence. Central to this process are senescent cells, which, through the senescence-associated secretory phenotype (SASP), contribute to chronic inflammation and tissue dysfunction. …”
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  2. 422
  3. 423

    Cellular Automaton Simulation Model for Predicting the Microstructure Evolution of an Additively Manufactured X30Mn21 Austenitic Advanced High-Strength Steel by Ashutosh Singh, Christian Haase, Luis A. Barrales-Mora

    Published 2025-07-01
    “…This work introduces an innovative parallelized Cellular Automaton (CA) framework for modeling the evolution of the microstructure during the LPBF process. …”
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  4. 424

    Circadian Intervention Improves Parkinson’s Disease and May Slow Disease Progression: A Ten Year Retrospective Study by Gregory Willis, Takuyuki Endo, Murray Waldman

    Published 2024-11-01
    “…Conclusions: The sequence of improvement in prodromal symptoms and motor function seen here parallels the slow, incremental repair process mimicking the protracted degenerative sequelae of PD that extends over decades. …”
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  5. 425

    Toward Cyborg: Exploring Long-Term Clinical Outcomes of a Multi-Degree-of-Freedom Myoelectric Prosthetic Hand by Yuki Kuroda, Yusuke Yamanoi, Hai Jiang, Yoshiko Yabuki, Yuki Inoue, Dianchun Bai, Yinlai Jiang, Jinying Zhu, Hiroshi Yokoi

    Published 2025-01-01
    “…Progress in this field has been directed toward employing machine-learning algorithms to process electromyogram patterns, enabling a broad spectrum of hand movements. …”
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  6. 426

    How Babies Learn to Move: An Applied Riemannian Geometry Theory of the Development of Visually-Guided Movement Synergies by Peter D. Neilson, Megan D. Neilson

    Published 2025-05-01
    “…Consequently, we propose that, as part of motor and visual development, starting with bootstrapping by fetal and neonatal pattern-generator movements and continuing adaptively from infancy to adulthood, most of the computation is carried out in advance and stored in a motor association memory network. From there it can be quickly retrieved by a selection process that provides the appropriate movement synergy compatible with the particular visual goal. …”
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  7. 427

    Self-navigating the “Island of Reil”: a systematic review of real-time fMRI neurofeedback training of insula activity by Yuan Zhang, Benjamin Becker, Keith M. Kendrick, Qiong Zhang, Shuxia Yao

    Published 2025-05-01
    “…The crucial role of the insula in emotional and salience processing makes it one of the most commonly targeted regions in previous rtfMRI studies. …”
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  8. 428

    Forced Migrant Counter Cultural (Co)Productions by Phoebe Kisubi Mbasalaki, Kalemba Kizito

    Published 2024-12-01
    “…Drawing on empirical research done in South Africa in 2022, both narration and the documentary film became potent modes of knowledge co‐production, illuminating how cultural productions contribute to shaping our understanding of forced migration and its associated challenges. Emphasising the prevalence of anti‐migrant rhetoric in South Africa and the prevalence of violence meted out against (forced) African migrant workers, this article identifies parallels with global discourses surrounding migrancy, where false nationalisms vilify migrants as scapegoats for societal issues. …”
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  9. 429

    THE NON-(POST)CLASSICAL WORLDVIEW IN NATIONAL LITERARY HISTORY: R. AKHMETZYANOV’S LYRICS by Vera R. Amineva

    Published 2016-12-01
    “…The principle of poetic and figurative architectonics is associated with the law of polygenres and polystylistics responsible for the integrity of the analyzed works.…”
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  11. 431

    Neural dynamics of personality trait perception and interaction preferences by Martin Weiß, Marko Paelecke, Patrick Mussel, Grit Hein

    Published 2024-12-01
    “…Abstract According to recent research, self-reported Big Five personality traits are associated with preferences for faces that are representative of certain Big Five traits. …”
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  12. 432

    Shepherding DNA ends: Rif1 protects telomeres and chromosome breaks by Mario Alberto Flores-Valdez, Gabriele A. Fontana, Julia K. Reinert, Nicolas H. Thomä, Ulrich Rass

    Published 2018-05-01
    “…While this functional dichotomy has long been a puzzle, recent findings link yeast Rif1 not only to telomeres, but also to DSB repair, and mechanistic parallels likely exist. In this review, we will provide an overview of the actions of Rif1 at DNA ends and explore how exclusion of end-processing factors might be the underlying principle allowing Rif1 to fulfill diverse biological roles at telomeres and chromosome breaks.…”
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  13. 433

    Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in Drosophila prostate-like secondary cells. by Aashika Sekar, Aaron Leiblich, S Mark Wainwright, Cláudia C Mendes, Dhruv Sarma, Josephine E E U Hellberg, Carina Gandy, Deborah C I Goberdhan, Freddie C Hamdy, Clive Wilson

    Published 2023-06-01
    “…The changes observed share mechanistic parallels with the pathological switch to hormone-independent AR signalling seen in CRPC, suggesting that the latter may reflect the dysregulation of a currently unidentified physiological process.…”
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    Evaluating Colilert and ChromAgar methods for the detection of ESBL bacteria in water samples from urban markets in Blantyre, Malawi by Miss Effita Masoamphambe, Dr Derek Cocker, Prof Nicholas Feasey, Dr Kondwani Chidziwitsano, Miss Mindy Panulo, Dr David Berendes, Dr Amy Kirby, Prof Tracy Morse

    Published 2025-03-01
    “…Samples were processed via conventional culture methods using ESBL CHROMagar™ media alongside paralleled testing with an IDEXX Colilert Quanti-tray method, in the presence of ceftriaxone (1ug/ml) to identify ESBL E. coli. …”
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  16. 436

    Construction and functional identification of overexpression vector of the peach PpCLH1 gene by LIU Xin, ZHANG Xiaoyu, MENG Junren, LI Ang, DUAN Wenyi, SUN Shihang, PAN Lei, ZENG Wenfang, WANG Zhiqiang, NIU Liang

    Published 2025-03-01
    “…This analysis unveiled a low expression level of PpCLH1 30 days prior to fruit maturation, characterized by a distinct green pericarp. As the ripening process unfolded, the pericarp transitioned to a paler green hue, paralleled by a surge in PpCLH1 transcript abundance. …”
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  17. 437

    Distinct changes in carbon, nitrogen, and phosphorus cycling in the litter layer across two contrasting forest–tundra ecotones by F. Hagedorn, J. Imboden, P. A. Moiseev, D. Gao, D. Gao, E. Frossard, P. Schleppi, D. Christen, K. Gavazov, J. Fetzer, J. Fetzer

    Published 2025-06-01
    “…Our study assesses how the vegetation shift affects the quality and elemental composition of the litter layer and consequently the microbial processing and nutrient release during decomposition. …”
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  18. 438