Biomarkers in glioblastoma and degenerative CNS diseases: defining new advances in clinical usefulness and therapeutic molecular target by Fan Bu, Jifa Zhong, Ruiqian Guan

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Characterization of lactylation modification subtypes and the promoting role of CCL20 in hepatocellular carcinoma progression by Li-Hong Wu, Liu Yang, Xiang-Xu Wang, Shuang Bai, Xi Yan, Jing Wei, Jun Wang, Fei Tian

“…A lactylation modification-related prognostic model was subsequently constructed using LASSO-Cox and multivariate Cox regression analyses. The CIBERSORT algorithm was utilized to analyze immune cell infiltration. …”
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Evaluating the role of insulin resistance in chronic intestinal health issues: NHANES study findings by Dongyao Zhao, Meihua Zhao, Bing Gao, He Lu

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LASSO-mCGA: Machine Learning and Modified Compact Genetic Algorithm-Based Biomarker Selection for Breast Cancer Subtype Classification by Nimisha Ghosh, Sankar Kumar Mridha, Rourab Paul

“…Being a heterogeneous disease, subtyping breast cancer plays a vital role in its treatment. In this regard, gene expression plays an important role. …”
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Applicability of Statins in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) by Thaninee Prasoppokakorn

“…Metabolic dysfunction-associated steatotic liver disease (MASLD) is the novel terminology encompassing liver disease associated with metabolic dysfunction, replacing the previous terminology of non-alcoholic fatty liver disease (NAFLD). …”
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CENPF as a Potential Biomarker Associated with the Immune Microenvironment of Renal Cancer by Meilin Chen MS, Xiuxin Tang MS, YanPing Liang MD, Tangdang Ding MS, Meifang He PhD, Dong Wang PhD, Ruizhi Wang PhD

“…This study aimed to investigate the role of Centromere Protein F (CENPF) as a potential prognostic biomarker for renal cancer. …”
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Left ventricular noncompaction associated with titin-truncating variants in the TTN gene by Yu. A. Vakhrushev, T. I. Vershinina, P. A. Fedotov, A. A. Kozyreva, A. M. Kiselev, Yu. V. Fomicheva, E. S. Vasichkina, T. M. Pervunina, A. A. Kostareva

“…Aim. To study the association of genetic variants in the titin gene (TTN) with the development and clinical course of left ventricular noncompaction in different age groups.Material and methods. …”
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Multicellular model of neuroblastoma proposes unconventional therapy based on multiple roles of p53. by Kenneth Y Wertheim, Robert Chisholm, Paul Richmond, Dawn Walker

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Hair loss: The role of nutritional support in a comprehensive approach to hair loss treatment by Anna I. Krylova, Spartak F. Kaiumov, Maria I. Vasil’eva

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Teaching Internal Medicine Residents to Critically Appraise the Role of Race in Pulmonary Function Testing by Ananya Bhatia-Lin, Nirav Bhakta, Neha Deshpande, Laura Granados, Rosemary Adamson

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Exploring the role of neutrophil extracellular traps in neuroblastoma: identification of molecular subtypes and prognostic implications by Can Qi, Can Qi, Ziwei Zhao, Lin Chen, Le Wang, Yun Zhou, Guochen Duan, Guochen Duan

“…Univariate Cox analysis and the LASSO algorithm were used to identify biomarkers for prognosis. …”
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An Effective GTO Algorithm-Based Cost-Benefit Analysis of DISCOs by Optimal Allocation of DG and DSTATCOM in a Radial Distribution Network by RAM PRASAD KANNEMADUGU, V. Adhimoorthy, A. Lakshmi Devi

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Development of a prognostic model for breast cancer patients based on intratumoral tumor-infiltrating lymphocytes using machine learning algorithms by Xinyi Wu, Chun Li

“…Employing consensus clustering and Weighted Correlation Network Analysis (WGCNA), we identified iTIL-associated hub genes. Our iTIL-centric signature was developed using a machine learning framework integrating 101 algorithms, validated across independent testing sets. …”
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Identification of novel metabolism-related biomarkers of Kawasaki disease by integrating single-cell RNA sequencing analysis and machine learning algorithms by Chenhui Feng, Zhimiao Wei, Xiaohui Li, Xiaohui Li

“…Through differential expressed genes (DEG) analysis, high-dimensional Weighted Correlation Network Analysis (hdWGCNA) and machine learning algorithms, we identified signature genes associated with both BAM and FAM. …”
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The role and machine learning analysis of mitochondrial autophagy-related gene expression in lung adenocarcinoma by Binyu Wang, Di Liu, Danfei Shi, Xinmin Li, Yong Li

“…This study aims to investigate the relationship between gene expression and mitophagy in LUAD, with an emphasis on identifying key biomarkers and elucidating their roles in tumorigenesis and immune cell infiltration.MethodsWe utilized datasets GSE151101 and GSE203609 from the Gene Expression Omnibus (GEO) database to identify differentially expressed genes (DEGs) associated with lung cancer and mitophagy. …”
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Preeclampsia pathogenesis and prediction - where are we now: the focus on the role of galectins and miRNAs by Natasa Karadzov Orlic, Ivana Joksić

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Exploring the role of hepsin in prostate cancer: bioinformatics, molecular Docking and molecular dynamics simulations by Hongying Peng, Dan Du, Zhonggui Hu, Zhiliang Xia

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Single-Cell Transcriptomics Unveils the Mechanistic Role of FOSL1 in Cutaneous Wound Healing by Jingbi Meng, Ge Zheng, Yinli Luo, Ling Ge, Zhiqing Liu, Wenhua Huang, Meitong Jin, Yanli Kong, Shanhua Xu, Zhehu Jin, Longquan Pi

“…Machine learning algorithms were instrumental in identifying pivotal genes, a finding corroborated through animal modeling and Western blot analysis of tissue samples. …”
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The growth of computer-assisted (robotic) surgery in urology 2000–2014: The role of Asian surgeons by Deepansh Dalela, Rajesh Ahlawat, Akshay Sood, Wooju Jeong, Mahendra Bhandari, Mani Menon

“…Objective: A major role in the establishment of computer-assisted robotic surgery (CARS) can be traced to the work of Mani Menon at Vattikuti Urology Institute (VUI), and of many surgeons of Asian origin. …”
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Role of inflammation-related genes as prognostic biomarkers and mechanistic implications in idiopathic pulmonary fibrosis by Bing Bai, Bing Bai, Bing Bai, Wenfei Zhao, Fazhan Li, Yang Mi, Pengyuan Zheng

“…IntroductionIdiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive lung disorder characterized by excessive fibrosis and structural remodeling of lung tissue. The role of inflammation in developing and progressing IPF is increasingly recognized as critical. …”
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