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941
Identification of a Hypoxia-Angiogenesis lncRNA Signature Participating in Immunosuppression in Gastric Cancer
Published 2022-01-01“…However, their collective function’s prognostic and biological roles were not reported in gastric cancer. Hence, we aimed to investigate the effects of hypoxia and angiogenesis on gastric cancer via sequencing data. …”
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942
PLOD3 as a novel oncogene in prognostic and immune infiltration risk model based on multi-machine learning in cervical cancer
Published 2025-03-01“…We identified 112 key metabolic genes, which were used to construct and validate a prognostic model through various machine learning algorithms. GO and KEGG enrichment analysis revealed the MAPK cascade plays a crucial role in metabolic processes. …”
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943
Palmitoylation-related gene ZDHHC22 as a potential diagnostic and immunomodulatory target in Alzheimer’s disease: insights from machine learning analyses and WGCNA
Published 2025-01-01“…Methods This study retrieved AD data sets from the GEO database to identify palmitoylation-associated genes (PRGs). This study applied WGCNA along with three machine learning algorithms—random forest, LASSO regression, and SVM–RFE—to further select key PRGs (KPRGs). …”
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944
Leveraging machine learning to identify determinants of zero utilization of maternal continuum of care in Ethiopia: Insights from SHAP analysis and the 2019 mini DHS.
Published 2025-01-01“…The findings highlight the critical role of socioeconomic, demographic, and regional factors in maternal care utilization in Ethiopia. …”
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945
Identification and mechanistic insights of cell senescence-related genes in psoriasis
Published 2025-01-01“…Recent studies have suggested that cell senescence, a state in which cells cease to divide and secrete inflammatory mediators, plays a critical role in various chronic diseases, including psoriasis. …”
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946
Castleman Disease: Insights from a Case Series and Literature Review
“…Diagnostic challenges included differentiating CD from malignancies or autoimmune disorders, emphasizing the critical role of histopathology. UCD pathogenesis may involve follicular dendritic cell mutations, whereas MCD subtypes are driven by human herpesvirus (HHV)-8-associated viral interleukin-6 or idiopathic cytokine dysregulation. …”
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947
FAR1 as a ferroptosis-related biomarker and potential therapeutic target in acute kidney injury: integrated bioinformatics and experimental validation
Published 2025-12-01“…Diagnostic biomarkers were then selected using LASSO, RFE, and RF algorithms. Additionally, small pharmacological molecules associated with DE-FRGs were identified to explore the connection between DE-FRGs and AKI. qRT-PCR analysis revealed FAR1 expression in AKI, while Western blotting and IHC confirmed corresponding FAR1 protein changes in kidney tissues. …”
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948
Identification of CXCR4 as a potential preventive gene in clear cell renal cell carcinoma from machine learning and immune analysis
Published 2025-07-01“…LASSO, SVM-RFE, and RF algorithms are used to identify the key gene CXCR4 associated with ccRCC. …”
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949
Identifying nexilin as a central gene in neutrophil-driven abdominal aortic aneurysm pathogenesis
Published 2025-03-01“…Conclusion NEXN plays a crucial role in modulating neutrophil infiltration in AAA. …”
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950
Public Perceptions of Ethical Challenges and Opportunities for Enterprises in the Digital Age
Published 2025-06-01“…Statistical analysis demonstrated positive and significant associations: Data privacy and ethical prioritisation (t-value = 45, p < 0.001), Algorithmic ethics and ethical prioritisation (B = 0.35, p = 0.004), Factor analysis identified three critical variables: data privacy and security, ethical algorithms and workforce displacement accounted for 75% of the variance on average. …”
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951
Geospatial brain-inspired navigation: a neurocognitive approach for autonomous systems in complex environments
Published 2025-08-01“…To address these challenges, it is essential to explore the roles and functional connectivity of distinct brain regions involved in processing real-world geospatial information and integrate these insights into autonomous navigation algorithms. …”
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952
DISCERN: deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection
Published 2023-09-01“…We show that DISCERN is robust against differences between batches and is able to keep biological differences between batches, which is a common problem for imputation and batch correction algorithms. We use DISCERN to detect two unseen COVID-19-associated T cell types, cytotoxic CD4+ and CD8+ Tc2 T helper cells, with a potential role in adverse disease outcome. …”
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953
Application of Concentration-Area fractal modeling and artificial neural network to identify Cu, Zn±Pb geochemical anomalies in Hashtjin area, NW of Iran
Published 2024-10-01“…Identification of geochemical anomalies plays an essential role in mineral exploration. Recent research investigations have shown that Machine Learning (ML) algorithms can identify geochemical anomalies associated with mineralization that represent targets for mineral exploration. …”
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954
Leveraging Large Language Models for Integrated Satellite-Aerial-Terrestrial Networks: Recent Advances and Future Directions
Published 2025-01-01“…We outline the current architecture of ISATNs and highlight the significant role LLMs can play in optimizing data flow, signal processing, and network management to advance 5G/6G communication technologies through advanced predictive algorithms and real-time decision-making. …”
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955
RNA m7G methylation regulators and targets significantly contribute to chronic obstructive pulmonary disease
Published 2025-03-01“…Abstract Chronic obstructive pulmonary disease (COPD) is one of the most common lung injury diseases, closely associated with aging, air pollution and smoking exposure. …”
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956
Machine learning-based prognostic modeling integrating PANoptosis in head and neck squamous cell carcinoma
Published 2025-04-01“…Abstract Background Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous and aggressive cancer, posing challenges for prognosis and treatment. The role of PANoptosis in HNSCC remains unclear, despite its potential impact on the tumor immune microenvironment. …”
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957
Prognostic model identification of ribosome biogenesis-related genes in pancreatic cancer based on multiple machine learning analyses
Published 2025-05-01“…Prognostic gene sets were screened using machine learning algorithms to construct a risk model, which was externally validated via GEO database. …”
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958
AI-assisted ophthalmic imaging for early detection of neurodegenerative diseases
Published 2025-05-01“…Methods This review examines clinical applications of AI in identifying retinal biomarkers associated with neurodegenerative diseases. Relevant data was gathered through a comprehensive literature review using PubMed, ScienceDirect, and Google Scholar to evaluate studies utilizing AI algorithms for retinal imaging analysis, focusing on diagnostic performance, sensitivity, specificity, and clinical relevance. …”
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959
A Comparative Study of Data-Driven Prognostic Approaches under Training Data Deficiency
Published 2024-09-01“…In industrial system health management, prognostics play a crucial role in ensuring safety and enhancing system availability. …”
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960
Integrated analysis unraveling the immunologic and clinical prognostic values of synaptotagmin like 4 in pan-cancer
Published 2025-06-01“…We use multiple immune infiltration algorithms in TIMER2.0 and TISCH database to cross-verify the associations between SYTL4 expression and tumor immune microenvironment. …”
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