Identification and validation of TUBB, CLTA, and FBXL5 as potential diagnostic markers of postmenopausal osteoporosis by Yue Tan, Yujing Wang, Qin Zhu, Yan Xue, Xuhao Ji, Zhenkun Li, Jiawen Shen, Chengming Sun, Shiqi Ren, Chenlin Zhang, Jianfeng Chen

“…N6-methyladenosine (m6A) is one of the most common RNA modifications influencing the progression of various disorders; however, its specific role in PMOP remains unexplored. This study aims to investigate the expression profiles of m6A-related genes and their impact on the prognosis of PMOP patients. …”
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Gravity‐Derived Antarctic Crustal Thickness Based on the Gauss‐FFT Method by Fei Ji, Leyuan Wu, Qiao Zhang

“…The distinctive negative isostatic anomalies are observed in the Transantarctic Mountains and the East Antarctic areas of the great escarpment in the Dronning Maud Land and Aurora and Wilkes Subglacial Basin, indicating that the low density of the uppermost mantle and lithospheric strength may play important roles in compensating for their elevations. Variations in crustal thickness in interior East Antarctica are analyzed; the thickened crust from Dronning Maud Land to the Gamburtsev Subglacial Mountains may be associated with the collision of continental blocks and is interpreted as the fossil sutures. …”
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Circulating MicroRNAs as Novel Biomarkers in Risk Assessment and Prognosis of Coronary Artery Disease by Chiara Vavassori, Eleonora Cipriani, Gualtiero Ivanoe Colombo

“…Nevertheless, available cardiovascular risk prediction algorithms still miss a significant portion of individuals at-risk. …”
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Impact of Subjective and Objective Green Space Characteristics on Mental Health Benefits: An Explainable Machine Learning Approach by Ke LI, Yipei MAO, Yongjun LI

“…Secondly, subjective green space characteristics play a prominent role in influencing mental health benefits. The combined influence of perceived attractiveness and perceived greenness is the most significant. …”
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AI language and emotional support as a physician assistant in hypertension management: an N-of-1 case study on virtual encouragement and blood pressure control by Abdullah Al Fraidan

“…Abstract This study explores the role of an AI assistant in supporting hypertension management by providing both emotional and behavioral reinforcement. …”
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The application of blockchain with a comparative approach and its impact on risk, flexibility and internal control evaluation by mohammadsadegh aminipoor, HamidReza GholamniaRoshan, azadeh kiapour, Iman Dadashi

“…These features can reduce the risks associated with fraud, theft and unauthorized changes. …”
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DGCLCMI: a deep graph collaboration learning method to predict circRNA-miRNA interactions by Chao Cao, Mengli Li, Chunyu Wang, Lei Xu, Quan Zou, Yansu Wang, Wu Han

“…It facilitates the discovery of unknown associations and sheds light on their roles in physiological processes.…”
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Predictive reward-prediction errors of climbing fiber inputs integrate modular reinforcement learning with supervised learning. by Huu Hoang, Shinichiro Tsutsumi, Masanori Matsuzaki, Masanobu Kano, Keisuke Toyama, Kazuo Kitamura, Mitsuo Kawato

“…Although the cerebellum is typically associated with supervised learning algorithms, it also exhibits extensive involvement in reward processing. …”
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Carbon stock dynamics of forest to oil palm plantation conversion for ecosystem rehabilitation planning by D. Frianto, E. Sutrisno, A. Wahyudi, E. Novriyanti, W.C. Adinugroho, A.S. Yunianto, H. Kurniawan, H. Khotimah, A. Windyoningrum, I.W.S. Dharmawan, H.L. Tata, S. Suharti, H.H. Rachmat, E.M. Lim

“…Data analysis was carried out using Classification and Regression Tree, a decision tree algorithm used in machine learning for guided classification. …”
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Unraveling anoikis in glioblastoma: insights from single-cell sequencing and prognostic modeling by Qikai Tang, Chenfeng Ma, Jiaheng Xie, Qixiang Zhang, Bingtao Zhang, Weiqi Bian, Qingyu Lu, Zeyu Wan, Wei Wu

“…Objectives This study aimed to investigate the role of anoikis—a mechanism by which cells evade programmed cell death upon detachment from the extracellular matrix—in GBM progression and prognosis. …”
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Rural Landscape Characters and Spatial Correlation Mechanism in the Tiaoxi River – Canal Basin in Zhejiang Province by Lin ZHANG, You ZUO, Binyi LIU

“…At the river − canal basin scale, the multi-level spatial superposition technique is utilized to identify associative character zones, and a coupling coordination model is used to identify the correlation patterns of water network， canal channel and rural landscape. …”
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Using Digital Technology to Conduct COVID-19 Surveillance: A Systematic Review by Fitrisia Rahma, Fatmah Fatmah, Rachmadhi Purwana

“…However, there is limited  knowledge about the role of digital technology in COVID-19, including its challenges. …”
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Unveiling PANoptosis in Acute Kidney Injury: An Integrative Multi-Dimensional Approach to Identify Key Biomarkers by Wang N, Zhang L, Xu Z, Xu Q, Lu Y, Niu P, Yan L, Wang L, Cao H, Shao F

“…Through integrating these DEGs, a candidate gene set associated with PANoptosis was established. Several machine learning algorithms were employed to determine the optimal feature genes. …”
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Targeting childhood loneliness in china: in silico interventions and moderated network analysis by Xinle Yu, Xuanzhi Zhang, Kusheng Wu, Zhenqiang Xu, Zhiya Liang, Wanyi Wen, Dinghui Wang, Yanhong Huang

“…In silico interventions using the NodeIdentifyR algorithm (NIRA) within an Ising model identified effective targets for prevention and intervention. …”
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Systematic identification and targeting of master regulator checkpoints (MRC) governing tumor microenvironment-mediated immune evasion by Pasquale Laise, Andrea Califano, Xiaoyun Sun, Gideon Bosker, Mariana Babor, Stuart Andrews, Lorenzo Tomassoni, Mariano Alvarez

“…We hypothesize that the immune-evasive role of TIME subpopulations—including regulatory T cells, cancer-associated fibroblasts, and tumor-associated macrophages—is critically mediated by hyperconnected Master Regulator Checkpoint (MRC) modules whose aberrant activity, as induced by paracrine signals, can be abrogated or modulated either genetically or pharmacologically. …”
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Single-cell transcriptomics in colorectal cancer uncover the potential of metastasis and immune dysregulation of a cell cluster overexpressed PRSS22 by Chengyuan Xu, Ziheng Zhou, Dongfei Zhu, Qingyun Zhang, Shoubin Zhong, Zhenhua Li

“…Subsequently, Boruta feature selection algorithm was combined to identify prognosis related genes. …”
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The signature based on interleukin family and receptors identified IL19 and IL20RA in promoting nephroblastoma progression through STAT3 pathway by Chen Ding, Hongjie Gao, Liting Zhang, Zhiyi Lu, Bowen Zhang, Ding Li, Fengyin Sun

“…Interleukin (receptors) (IL(R)s) play significant roles in tumor biology, however, their specific involvement in WT remains inadequately understood. …”
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Autophagy crosstalk with the immune microenvironment in chronic myeloid leukemia and serves as a biomarker for diagnosis and progression by Fangmin Zhong, Fangyi Yao, Jing Liu, Qun Fang, Xiajing Yu, Bo Huang, Xiaozhong Wang

“…A consensus clustering algorithm was used to identify autophagy-related molecular subtypes. …”
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Identification and validation of susceptibility modules and hub genes of adrenocortical carcinoma through WGCNA and machine learning by Yaoming Yang, Xinbao Wang, Liuqing Wu, Shihua Zhao, Ran Chen, Guoyong Yu

“…Results The enrichment analysis revealed that pathways associated with cell division, protein synthesis, and metabolism play significant roles in the progression of ACC. …”
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Novel Insights into Non-Invasive Diagnostic Techniques for Cardiac Amyloidosis: A Critical Review by Marco Maria Dicorato, Paolo Basile, Giuseppe Muscogiuri, Maria Cristina Carella, Maria Ludovica Naccarati, Ilaria Dentamaro, Marco Guglielmo, Andrea Baggiano, Saima Mushtaq, Laura Fusini, Gianluca Pontone, Cinzia Forleo, Marco Matteo Ciccone, Andrea Igoren Guaricci

“…Non-invasive diagnostic techniques play a central role in the suspicion and detection of CA, also thanks to the continuous scientific and technological advances in these tools. …”
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