Integrative genomic analysis and diagnostic modeling of osteoporosis: unraveling the interplay of autophagy, osteogenesis, adipogenesis, and immune infiltration by Lin-Jing Han, Jian-Zong Zhu, Jian-Zong Zhu, Hong-Cai Liu, Xiao-Sheng Lin, Xiao-Sheng Lin, Shu-Zhong Yang

“…The study underscores the importance of personalized treatment and the potential role of immune modulation in managing OP.…”
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Demethylase FTO mediates m6A modification of ENST00000619282 to promote apoptosis escape in rheumatoid arthritis and the intervention effect of Xinfeng Capsule by Fanfan Wang, Fanfan Wang, Jianting Wen, Jianting Wen, Jian Liu, Jian Liu, Ling Xin, Yanyan Fang, Yanyan Fang, Yue Sun, Mingyu He, Mingyu He

“…This study aimed to elucidate the mechanism by which the demethylase FTO promoted FLS apoptosis escape through the m6A modification of lncRNA ENST00000619282 and to reveal the therapeutic targets of XFC in treating RA by intervening in this m6A-dependent pathway.MethodsA retrospective analysis was conducted on 1603 RA patients using association rule mining and random walk algorithms to evaluate the efficacy of XFC. …”
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Exploring the relationship between sepsis and Golgi apparatus dysfunction: bioinformatics insights and diagnostic marker discovery by Wanli Ma, Xinyi Liu, Ran Yu, Jiannan Song, Lina Hou, Ying Guo, Hongwei Wu, Dandan Feng, Qi Zhou, Haibo Li

“…We identified differentially expressed genes (DEGs). These DEGs, Golgi-associated genes obtained from the MSigDB database, and key modules identified through WGCNA were intersected to determine Golgi-associated differentially expressed genes (GARGs) linked to sepsis. …”
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PSTR: A Test Case Reuse Method Based on Path Similarity by Xinyue Xu, Sinong Chen, Zhonghao Guo, Xiangxian Chen

“…Finally, the path similarity algorithm compares paths between the old and new versions, allowing test cases associated with the most similar paths to be reused for the new version. …”
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The prognostic significance of long noncoding RNAs in bladder cancer: A meta-analysis. by Yuexin Xia, Zhiyuan Liu, Weijian Yu, Shihang Zhou, Linnan Shao, Wenqian Song, Ming Liu

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TILTomorrow today: dynamic factors predicting changes in intracranial pressure treatment intensity after traumatic brain injury by Shubhayu Bhattacharyay, Florian D. van Leeuwen, Erta Beqiri, Cecilia A. I. Åkerlund, Lindsay Wilson, Ewout W. Steyerberg, David W. Nelson, Andrew I. R. Maas, David K. Menon, Ari Ercole, the CENTER-TBI investigators and participants

“…Serial protein biomarkers were also important and may serve a useful role in the clinical armamentarium for assessing therapeutic needs. …”
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Utility of serum Aspergillus-galactomannan antigen to evaluate the risk of severe acute exacerbation in chronic obstructive pulmonary disease. by Katsuhiro Yoshimura, Yuzo Suzuki, Yusuke Inoue, Koji Nishimoto, Kazutaka Mori, Masato Karayama, Hironao Hozumi, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Naoki Inui, Koushi Yokomura, Shiro Imokawa, Takafumi Suda

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Emergency Medical Care for Victims with Crush Syndrome at the Pre-Hospital Stage by V. Orlyk

“…The study emphasizes that assistance for CS-victims must be organized according to a clear and coordinated algorithm corresponding to evacuation zones - at the scene, in red, yellow, and green zones, as well as during transportation and hospitalization. …”
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CYLD as a key regulator of myocardial infarction-to-heart failure transition revealed by multi-omics integration by Jingya Xu, Jingya Xu, Zhonghua Dong, Zhaodong Li, Xuan Wang, Xuan Wang

“…These hubs were significantly associated with immune-related processes, suggesting their potential role in the pathogenesis of HF after MI. …”
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Perspective of Chinese GF-1 high-resolution satellite data in agricultural remote sensing monitoring by Qing-bo ZHOU, Qiang-yi YU, Jia LIU, Wen-bin WU, Hua-jun TANG

“…High-resolution satellite data have been playing an important role in agricultural remote sensing monitoring. However, the major data sources of high-resolution images are not owned by China. …”
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Identification of Disulfidptosis-Related Genes and Molecular Subgroups in Rheumatoid Arthritis for Diagnostic Model and Patient Stratification by Liu X, Wang S, Du X, Wang Y, Mo L, Li H, Qu Z, Wang X, Sun J, Li Y, Wang J

“…The machine learning algorithms were used to identify the hub genes. Second, a diagnostic model was constructed for RA based on the hub genes. …”
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STUDYING DEVELOPMENT OF POST-VACCINAL CELLULAR IMMUNITY AGAINST BRUCELLOSIS BY MEANS OF LYMPHOCYTE <i>IN VITRO</i> TESTS USING AN EXPERIMENTAL ANTIGENIC COMPLEX by M. V. Kostyuchenko, E. L. Rakitina, D. G. Ponomarenko, O. V. Logvinenko, S. A. Kurcheva, T. V. Berdnikova, D. V. Rusanova, A. N. Kulichenko

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Identification and evaluation of metabolic mRNAs and key miRNAs in colorectal cancer liver metastasis by Guanxuan Chen, Shiwen Wang, Meng Zhang, Wenna Shi, Ruoyu Wang, Wanqi Zhu

“…Despite the established correlation between metabolic reprogramming of cancer cells and their proliferation, invasion, and metastasis, the specific role of metabolism-associated mRNAs in the liver metastasis of CRC remains unelucidated. …”
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Generalizing the arithmatic geometric mean — a hapless computer experiment by Jaak Peetre

“…However, no very conclusive results are obtained so the paper ends in a conjecture concerning the special rôle of the algorithms of Gauss and Borchardt. The paper discusses the asymptotic behavior of generalizations of the Gauss's arithmetic-geometric mean, associated with the names Meissel (1875) and Borchardt (1876). …”
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Microbial biomarker discovery in Parkinson’s disease through a network-based approach by Zhe Zhao, Jing Chen, Danhua Zhao, Baoyu Chen, Qi Wang, Yuan Li, Junyi Chen, Chaobo Bai, Xintong Guo, Nan Hu, Bingwei Zhang, Rongsheng Zhao, Junliang Yuan

“…Abstract Associations between the gut microbiota and Parkinson’s disease (PD) have been widely investigated. …”
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Interplay of a non-conjugative integrative element and a conjugative plasmid in the spread of antibiotic resistance via suicidal plasmid transfer from an aquaculture Vibrio isolate... by Lisa Nonaka, Tatsuya Yamamoto, Fumito Maruyama, Yuu Hirose, Yuki Onishi, Takeshi Kobayashi, Satoru Suzuki, Nobuhiko Nomura, Michiaki Masuda, Hirokazu Yano

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Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes. by Wipawee Wongchana, Pornrat Kongkavitoon, Pattarin Tangtanatakul, Chutamath Sittplangkoon, Patcharavadee Butta, Supatta Chawalitpong, Thitiporn Pattarakankul, Barbara A Osborne, Tanapat Palaga

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Constructing community in the Neolithic of southern Jordan: Quotidian practice in communal architecture. by Cheryl A Makarewicz, Bill Finlayson

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Biomarker identification for rheumatoid arthritis with inadequate response to DMARD and TNF therapies using multidimensional analyses by Leyuan Li, Hui Guo, Weijin Zhang, Xi Xiang, Jun Chi, Mengmeng Zhang, Jiali Chen, Zhimin Wang, Liping Dai

“…Differentially expressed genes (DEGs) closely associated with DMARD&TNF-IR RA were identified using the Limma R package. …”
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Translational repression by an RNA-binding protein promotes differentiation to infective forms in Trypanosoma cruzi. by Maria Albertina Romaniuk, Alberto Carlos Frasch, Alejandro Cassola

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