Multiple analytical perspectives of mitochondrial genes in the context of preeclampsia: potential diagnostic markers by Can Li, Can Li, Fang Liu, Chao Li, Xiangzhong Zhao, Qiulan Lv, Aiping Jiang, Shuping Zhao

“…Therefore, MMRDEGs may play a critical role in the mechanism of oxidative stress and inflammatory response in PE by mediating metabolic regulation and immune modulation, potentially serving as diagnostic biomarkers associated with mitochondrial metabolism in preeclampsia.…”
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A novel multi-task learning model based on Transformer-LSTM for wind power forecasting by Rongquan Zhang, Siqi Bu, Yuxia Zheng, Gangqiang Li, Xiupeng Wan, Qiangqiang Zeng, Min Zhou

“…The integration of multi-task learning into multi-step deterministic and probabilistic prediction frameworks plays a pivotal role in augmenting the accuracy of wind power forecasts and mitigating associated operational uncertainties. …”
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Lipid phosphate phosphatase 3 regulates adipocyte sphingolipid synthesis, but not developmental adipogenesis or diet-induced obesity in mice. by Lorenzo Federico, Liping Yang, Jason Brandon, Manikandan Panchatcharam, Hongmei Ren, Paul Mueller, Manjula Sunkara, Diana Escalante-Alcalde, Andrew J Morris, Susan S Smyth

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Actionable Variants of Unknown Significance in Inherited Arrhythmogenic Syndromes: A Further Step Forward in Genetic Diagnosis by Estefanía Martínez-Barrios, Andrea Greco, José Cruzalegui, Sergi Cesar, Nuria Díez-Escuté, Patricia Cerralbo, Fredy Chipa, Irene Zschaeck, Miguel Fogaça-da-Mata, Carles Díez-López, Elena Arbelo, Simone Grassi, Antonio Oliva, Rocío Toro, Georgia Sarquella-Brugada, Oscar Campuzano

“…<b>Conclusions:</b> We advocate for personalized disease-focused population frequency data and family segregation analyses for all rare variants that remain ambiguous to further clarify their role. The current ambiguity should not influence medical decisions, but a potential deleterious role would suggest a closer clinical follow-up and frequent genetic data review for a more personalized clinical approach.…”
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Prediction of Human Papillomavirus-Host Oncoprotein Interactions Using Deep Learning by Sheila Santa, Samuel Kojo Kwofie, Kwasi Agyenkwa-Mawuli, Osbourne Quaye, Charles A Brown, Emmanuel A Tagoe

“…Background: Human papillomavirus (HPV) causes disease through complex interactions between viral and host proteins, with the PI3K signaling pathway playing a key role. Proteins like AKT, IQGAP1, and MMP16 are involved in HPV-related cancer development. …”
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Identification and functional analysis of energy metabolism and pyroptosis-related genes in diabetic nephropathy by Shan He, Jian Ye, Yu Wang, Lu yang Xie, Si Yi Liu, Qin kai Chen

“…GSEA revealed significant enrichment of these genes in biological pathways associated with diabetic nephropathy. PPI network analysis highlighted the central role of these genes within the relevant pathways. …”
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Multiple-omics analysis of aggrephagy-related cellular patterns and development of an aggrephagy-related signature for hepatocellular carcinoma by Jiafen Xie, Xiaoming Wang

“…Abstract Background Protein aggrephagy, a selected autophagy process response for degrading protein aggregates, plays a critical role in various cancers. However, its regulatory mechanisms and clinical implications in hepatocellular carcinoma (HCC) remain largely unexplored. …”
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Using Deep Learning Techniques to Enhance Blood Cell Detection in Patients with Leukemia by Mahwish Ilyas, Muhammad Bilal, Nadia Malik, Hikmat Ullah Khan, Muhammad Ramzan, Anam Naz

“…Medical diagnosis plays a critical role in the early detection and treatment of diseases by examining symptoms and supporting findings through advanced laboratory testing. …”
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Significance of Immune-Related Genes in the Diagnosis and Classification of Intervertebral Disc Degeneration by Bo Wu, Xinzhou Huang, Mu Zhang, Wei Chu

“…With the extensive development of intervertebral disc degeneration (IDD) research, IDD has been found to be a complex disease associated with immune-related gene (IRGs) changes. …”
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Investigating and improving student understanding of the basics of quantum computing by Peter Hu, Yangqiuting Li, Chandralekha Singh

“…To prepare students for such opportunities, it is important to give them a strong foundation in the basics of QISE, in which quantum computing plays a central role. In this study, we discuss the development, validation, and evaluation of a Quantum Interactive Learning Tutorial, on the basics and applications of quantum computing. …”
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Cryptococcus neoformans urease affects the outcome of intracellular pathogenesis by modulating phagolysosomal pH. by Man Shun Fu, Carolina Coelho, Carlos M De Leon-Rodriguez, Diego C P Rossi, Emma Camacho, Eric H Jung, Madhura Kulkarni, Arturo Casadevall

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Genome-wide identification and expression analysis of phytochrome gene family in Aikang58 wheat (Triticum aestivum L.) by Zhu Yang, Zhu Yang, Wenjie Kan, Wenjie Kan, Ziqi Wang, Caiguo Tang, Yuan Cheng, Yuan Cheng, Dacheng Wang, Dacheng Wang, Yameng Gao, Lifang Wu, Lifang Wu

“…Phytochromes are essential photoreceptors in plants that sense red and far-red light, playing a vital role in regulating plant growth and development through light signal transduction. …”
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Exercise-changed gut mycobiome as a potential contributor to metabolic benefits in diabetes prevention: an integrative multi-omics study by Yao Wang, Jiarui Chen, Yueqiong Ni, Yan Liu, Xiang Gao, Michael Andrew Tse, Gianni Panagiotou, Aimin Xu

“…However, compared to the bacterial microbiome, the role of intestinal fungi in exercise remains elusive. …”
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Predicting immune status and gene mutations in stomach adenocarcinoma patients based on inflammatory response-related prognostic features by Huanjun Li, Jingtang Chen, Zhiliang Chen, Jingsheng Liao

“…Finally, scratch and transwell assays were performed to explore the role of SERPINE1 in STAD cells. Results We found that a high-inflammatory group was associated with poor prognosis in STAD patients. 14 inflammation-related DEGs out of 126 DEGs were identified to be associated with the prognosis of STAD patients, and the prognostic models and nomograms constructed from the subsequently identified key genes (SLC7A1, CD82, SERPINE1 ROS1 and SLC7A2) demonstrated a good predictive performance in terms of prognosis of STAD. …”
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TOM40 as a prognostic oncogene for oral squamous cell carcinoma prognosis by Lifei Deng, Hong Ran, Dunhui Yang, Zhen Wang, Peng Zhao, Hengjie Huang, Yongjin Wu, Peng Zhang

“…Abstract Background To investigate the role of the translocase of the outer mitochondrial membrane 40 (TOM40) in oral squamous cell carcinoma (OSCC) with the aim of identifying new biomarkers or potential therapeutic targets. …”
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Artificial Intelligence in Revolutionizing Kidney Care and Beyond: Kid-AI Revolution by Kounaina Khan, Farhan Zameer, Pratheek Jain, Ravi KR, Vidya Niranjan, Manoj S, Ravish H, Subrahmanya Padyana

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Integrin factor (FAM27E3), as a metastatic marker of papillary thyroid carcinoma, through the p53 signaling pathway promoting lymph node metastasis by Dong Zhang, Kai-Fang Xiang, Chen-Chen Hong, Xiao-Ping Bao, Yan Wu, Rui Wu

“…This study aims to explore the role and regulatory mechanism of the FAM27E3 in PTC lymph node metastasis.MethodThe seven thyroid cancer (THCA) datasets from the Gene Expression Omnibus (GEO) were combined as the training group, while the PTC dataset served as the testing group. …”
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Bioinformatics analysis and experimental studies reveal KPNA2 as a novel biomarker of hepatocellular carcinoma progression and telomere maintenance by Ke Ding, Lei Liu, Wang Yong, Beicheng Sun, Wenjie Zhang

“…A novel prognostic signature was then constructed using the LASSO Cox regression algorithm. Finally, in vitro experiments were conducted to explore the functional roles of the key hub gene KPNA2 in telomere maintenance, tumor growth, and metastasis in HCC. …”
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An analysis of cyclonic dominant patterns on cold period precipitation in the mid-western of Iran by Rastegar Mohammadi, mohammad saligheh, Mohammad Hossein Naserzadeh, Mehri Akbari

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Surveillance and Prevention of Fungal Infections in the Neonatal Intensive Care Unit by Prof Batyrbek Aslanov, Dr Larisa Ermakova, Dr Anna Nabieva

“…Introduction: Advances in the care of preterm neonates and newborns with congenital anomalies requiring hospitalization in intensive care units (ICU) have led to an increased population susceptible to healthcare-associated infections (HAIs), including those of fungal etiology. …”
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