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Molecular mechanisms of efferocytosis imbalance in the idiopathic pulmonary fibrosis microenvironment: from gene screening to dynamic regulation analysis
Published 2025-07-01“…In recent years, efferocytosis has been recognized as playing a crucial role in the occurrence and progression of IPF. This study aimed to identify and regulate key efferocytosis-related genes to elucidate their potential roles and clinical significance in IPF. …”
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503
Identification of lipid metabolism related immune markers in atherosclerosis through machine learning and experimental analysis
Published 2025-02-01“…Additionally, the ssGSEA algorithm further validated the association of these diagnostic genes with various immune cells. …”
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504
Factores clave en la práctica de la Ciencia Abierta. Un análisis multivariado en el contexto universitario = Key Factors in Open Science Practice: A Multivariate Analysis within th...
Published 2025-06-01“…Data were analyzed using descriptive statistical techniques, association tests, and multivariate analysis (binary logistic regression and K-means algorithm). …”
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505
A novel adenosine-to-inosine RNA editing-based nomogram for predicting prognosis of hepatocellular carcinoma
Published 2025-05-01“…Objective:Although the role of adenosine-to-inosine RNA editing (ATIRE) has gained widespread attention in multiple cancers, its predictive role in hepatocellular carcinoma (HCC) remains little known. …”
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506
Leveraging AlphaFold2 structural space exploration for generating drug target structures in structure-based virtual screening
Published 2025-09-01“…Computational virtual screening (VS) plays a vital role in early-stage drug discovery by enabling the efficient selection of candidate compounds and reducing associated costs. …”
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507
Deep-m6Am: a deep learning model for identifying N6, 2′-O-Dimethyladenosine (m6Am) sites using hybrid features
Published 2025-03-01“…Experimental results demonstrate that Deep-m6Am outperforms previous approaches by 6.67% and traditional ML algorithms by 7.39%.These findings highlight Deep-m6Am as a promising tool for advancing drug discovery and improving the diagnosis of diseases associated with m6Am modifications.…”
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508
Evolutionary Search with Multiple Utopian Reference Points in Decomposition-Based Multiobjective Optimization
Published 2019-01-01“…Decomposition-based multiobjective evolutionary algorithms (MOEA/Ds) have become increasingly popular in recent years. …”
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509
Using a Multivariate Virtual Experiment for Uncertainty Evaluation with Unknown Variance
Published 2024-10-01“…Moreover, the measurement model commonly employed for uncertainty evaluation according to JCGM-101 and JCGM-102 is not required for this algorithm, and only evaluations of the virtual experiment are performed to obtain an estimate and an associated uncertainty of the measurand. …”
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510
PRCFX-DT: a new graph-based approach for feature selection and classification of genomic sequences
Published 2025-06-01“…The proposed approach, which relies on the PageRank centrality algorithm, operates on codons that are associated with the nucleotide sequences. …”
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511
Pinpointing the integration of artificial intelligence in liver cancer immune microenvironment
Published 2024-12-01“…Emerging evidence underscores the critical roles of the immune microenvironment in tumor initiation, development, prognosis, and therapeutic responsiveness. …”
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512
Radiomics machine learning based on asymmetrically prominent cortical and deep medullary veins combined with clinical features to predict prognosis in acute ischemic stroke: a retr...
Published 2025-06-01“…An APCV-DMV radiomic model was created via the SVM algorithm, and independent clinical risk factors associated with AIS were combined with the radiomic model to generate a joint model. …”
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513
Molecular function validation and prognostic value analysis of the cuproptosis-related gene ferredoxin 1 in papillary thyroid carcinoma
Published 2025-07-01“…Abstract Cuproptosis, a copper-dependent distinct form of cell death, holds a critical role in tumor development. However, further investigation is needed to elucidate the impact of the cuproptosis signaling on thyroid cancer. …”
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514
Meta-analyses of IL1A polymorphisms and the risk of several autoimmune diseases published in databases.
Published 2018-01-01Get full text
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515
Advanced video anomaly detection using 2D CNN and stacked LSTM with deep active learning-based model
Published 2022-06-01“…Anomaly detection and its associated applications play a key role in the integrity of the system. …”
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516
Identification of a novel anoikis-related gene signature to predict prognosis and tumor microenvironment in intrahepatic cholangiocarcinoma carcinoma
Published 2025-06-01“…Finally, we used the CIBERSORT algorithm to investigate the correlation between risk scores and immune infiltration. …”
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517
Identification of cell adhesion-related subtypes and construction of risk model to predict breast cancer prognostic and immunological properties
Published 2025-04-01“…Cell adhesion molecules play a crucial role in modulating the interactions between tumor cells and surrounding cells. …”
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518
Integrative multi-omics and machine learning reveal critical functions of proliferating cells in prognosis and personalized treatment of lung adenocarcinoma
Published 2025-07-01“…Herein, we utilized multi-omics data and employed a multifaceted approach to delineate the proliferating cell landscape in LUAD. The Scissor algorithm was applied to identify Scissor+ proliferating cell genes associated with prognosis. …”
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Integrative bioinformatics analysis identifies METTL1 as a regulator of immune infiltration and prognosis in breast cancer
Published 2025-07-01“…These genes, along with METTL1, were positively associated with immunosuppressive cell types, such as regulatory T cells and follicular helper T cells, suggesting their role in shaping an immunosuppressive tumor microenvironment.…”
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520
Support of Epidemiological Well-Being during Regional Event with the International Participation
Published 2016-04-01“…Role of regional cultural mass events as potential threats for epidemics of the dangerous infectious diseases associated with implementation of external and internal epidemiological risks is demonstrated. …”
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