Advancing Marine Surveillance: A Hybrid Approach of Physics Infused Neural Network for Enhanced Vessel Tracking Using Automatic Identification System Data by Tasmiah Haque, Md Asif Bin Syed, Srinjoy Das, Imtiaz Ahmed

Get full text

A Complex Network of MicroRNAs Expressed in Brain and Genes Associated with Amyotrophic Lateral Sclerosis by Santosh Shinde, Neelima Arora, Utpal Bhadra

“…Amyotrophic Lateral Sclerosis (ALS) is a rare neurological disease affecting mainly motor neurons and often leads to paralysis and death in extreme cases. For exploring the role of microRNAs in genes regulation in ALS disease, miRanda was employed for prediction of target sites of miRNAs expressed in various parts of brain and CNS on 35 genes associated with ALS. …”
Get full text

Insights into Nitrogen-Associated Protein 50 (NAP50) as a Tyrosyl–DNA Phosphodiesterase in Dinoflagellates by Lu Tang, Nora Fung-Yee Tam, Winnie Lam, Thomas Chun-Hung Lee, Steven Jing-Liang Xu, Fred Wang-Fat Lee

“…The three-dimensional structure and biological functions of NAP50 are predicted using deep learning algorithms. Based on evolutionary relationships and functional predictions, NAP50 may play a role in repairing plastid DNA damage and potentially contribute to the transcription of plastid genes in dinoflagellates.…”
Get full text

Identification of hub genes for the diagnosis associated with heart failure using multiple cell death patterns by Hua‐jing Yuan, Hui Yu, Yi‐ding Yu, Xiu‐juan Liu, Wen‐wen Liu, Yi‐tao Xue, Yan Li

“…DHRS11 and LRKK2 were identified as PCD‐associated HF hub genes by machine learning algorithms. …”
Get full text

Integrated single-cell and transcriptome sequencing to construct a prognostic model of M2 macrophage-related genes in prostate cancer by TANG Kairan, FENG Chengling, HAN Bangmin

Get full text

Novel exosome-associated LncRNA model predicts colorectal cancer prognosis and drug response by Chi Zhou, Qian Qiu, Xinyu Liu, Tiantian Zhang, Leilei Liang, Yihang Yuan, Yufo Chen, Weijie Sun

“…In addition, two key exosome-associated LncRNA (MIR4713HG and ZEB1-AS1) were obtained, and a risk score (EALncRI) was constructed. …”
Get full text

Bioinformatic identification of signature miRNAs associated with fetoplacental vascular dysfunction in gestational diabetes mellitus by Yulan Lu, Chunhong Liu, Xiaoxia Pang, Xinghong Chen, Chunfang Wang, Huatuo Huang

“…Despite its clinical importance, the role of microRNAs (miRNAs) in fetoplacental vascular endothelial cell (VEC) programming in the context of GDM remains elusive. …”
Get full text

Identification and validation of key biomarkers associated with immune and oxidative stress for preeclampsia by WGCNA and machine learning by Tiantian Yu, Tiantian Yu, Tiantian Yu, Guiying Wang, Guiying Wang, Guiying Wang, Xia Xu, Xia Xu, Xia Xu, Jianying Yan, Jianying Yan, Jianying Yan

“…Notably, it shows a strong correlation with the immune microenvironment, suggesting its crucial role in the complex pathophysiological processes underlying PE.…”
Get full text

Role of diffuse endocrine system and cellular homeostasis of epithelial cells of the stomach mucosa in development and progression of peptic ulcer of the duodenum

Get full text

Machine learning identification of key genes in cardioembolic stroke and atherosclerosis: their association with pan-cancer and immune cells by Tianxiang Zhang, Chunhui Yuan, Mo Chen, Jinjiang Liu, Wei Shao, Ning Cheng

Get full text

The association between metabolomic profiles of lifestyle and the latent phase of incident chronic kidney disease in the UK Population by Tingting Jin, Yunqi Wu, Siyi Zhang, Ya Peng, Yao Lin, Saijun Zhou, Hongyan Liu, Pei Yu

“…Abstract Chronic kidney disease (CKD) is a global health challenge associated with lifestyle factors such as diet, alcohol, BMI, smoking, sleep, and physical activity. …”
Get full text

Characteristic expression profile of small nucleolar RNAs and their association with tumor immune microenvironment in papillary thyroid carcinoma by Qi-Lan Jiang, Fu-Yi Wang, Yuan Men, Yi-Huan Wu, Qin Xu, Yang Zeng, Jun Jiang

“…Furthermore, we applied CIBERSORTx and ESTIMATE algorithms to investigate the association between DE-snoRNA expression levels and clinicopathological features as well as tumor immune microenvironment in PTC. …”
Get full text

Identification of macrophage-associated diagnostic biomarkers and molecular subtypes in gestational diabetes mellitus based on machine learning by Kai Wei, Liyun Yuan, Yongsheng Ge, Han Yu, Guoping Zhao, Guoqing Zhang, Guohua Liu

Get full text

Characterization of key genes and immune cell infiltration associated with endometriosis through integrating bioinformatics and experimental analyses by Ying Peng, Xiangdong She, Ying Peng

“…We identified three key genes associated with EM: APLNR, HLA-DPA1, and AP1S2. The ssGSEA analysis results indicated that these genes play an important role in the development of EM. …”
Get full text

Exploration the role of pro-inflammatory fibroblasts and related markers in periodontitis: combing with scRNA-seq and bulk-seq data by Erli Wu, Feihan Gu, Qiangqiang Zhuo, Ziyang Gao, Yu Zhang, Jingjing Li, Xuan Yin, Weimin Bao, Xianqing Zhou, Feng Liang, Shouxiang Yang, Yuanyin Wang, Qingqing Wang, Qingqing Wang, Wei Shao, Wei Shao

“…Cell communication analysis revealed the specific role of PIGFs in periodontitis. Differential gene analysis, WGCNA, and machine learning algorithms identified two genes (MME and TSPAN11) as potential therapeutic targets for periodontitis. …”
Get full text

How Predictable Is Electric Vehicle Adoption? Exploring the Broader Role of Renewables in Transportation Using a Data-Driven Approach by Simona-Vasilica Oprea, Adela Bara

Get full text

The role of epigenetic regulation in pancreatic ductal adenocarcinoma progression and drug response: an integrative genomic and pharmacological prognostic prediction model by Kang Fu, Junzhe Su, Yiming Zhou, Xiaotong Chen, Xiao Hu

“…A machine learning-based prognostic model was constructed using multiple algorithms, including Lasso and Random Survival Forest. …”
Get full text

Pan-cancer analysis and validation of NT5DC2: emphasizing its prognostic significance and immunological role in TNBC by Qing Luo, Xiandong Xie, Luyao Tian, Xiaomin Gao, Shu Li, Jinqiu Zhang, Limei Mo, Xue Zhu, Ke Wang, Yongxiang Yin

“…Immune correlation analyses were performed using ESTIMATE and CIBERSORT algorithms. KEGG pathway enrichment analysis was used to explore NT5DC2-associated molecular pathways. …”
Get full text

A Review About the Effects of Digital Competences on Professional Recognition; The Mediating Role of Social Media and Structural Social Capital by Javier De la Hoz-Ruiz, Rawad Chaker, Lucía Fernández-Terol, Marta Olmo-Extremera

Get full text

Identification of stemness subtypes and prognostic modeling in thyroid cancer: the critical role of DPYSL3 in tumor progression and immune microenvironment by Jialong Yu, Wei Luo, Guangwei Xu, Mei Tao, Yuqi Wang, Qiman Dong, Linfei Hu, Xiukun Hou, Jingzhu Zhao, Dapeng Li, Songfeng Wei, Xianhui Ruan, Xiangqian Zheng

Get full text