Exploring the role of alternative lengthening of telomere-related genes in diagnostic modeling for non-alcoholic fatty liver disease by Nan Zhu, Xiaoliang Wang, Huiting Zhu, Yue Zheng

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ROLE OF COMPUTED TOMOGRAPHY WITH PNEUMOGASTROGRAPHY IN DETERMINING THE REGRESSION GRADE OF LOCALLY ADVANCED GASTRIC CANCER AFTER NEOADJUVANT CHEMOTHERAPY by I. D. Amelina, A. M. Karachun, D. V. Nesterov, L. N. Shevkunov, A. S. Artemieva, S. S. Bagnenko, S. L. Trofimov

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Association between pro-inflammatory diet and fecal incontinence: a large population-based study by Haiyang Wang, Haiyang Wang, Zihan Liu, Zihan Liu, Xingfu Lu, Enyu Luan, Enyu Luan, Tingting Dong, Tingting Dong, Can Li, Can Li, Yanni Lv, Erkang Wu, Tao Shen, Tao Shen

“…Meanwhile, we identified key dietary factors for FI using multiple machine learning algorithms. Finally, we assessed the mediation role of inflammatory indicators on the association of key dietary factors with FI through mediation analysis.ResultsAfter adjustment for potential confounding variables, our results showed the highest tertile exhibited dramatically increasing prevalence of FI compared to the lower tertile (OR 1.27, 95% CI 1.06–1.53), suggesting a positive association between DII and FI. …”
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Assessing the association of multi-environmental chemical exposures on metabolic syndrome: A machine learning approach by Yehoon Jo, Mi-Yeon Shin, Sungkyoon Kim

“…Emerging evidence suggests that environmental chemical exposures may play a significant role in the development of MetS by disrupting metabolic pathways. …”
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Association of marital status with DNA methylation-based biological age among US older adults by Xian Cui, Jianghua Huo, Yaqian Xu, Hui Zhang, Chongyu Ding, Jun Du, Xiangwei Li

“…BackgroundDNA methylation (DNAm) algorithms, such as GrimAge and GrimAge2, have emerged as reliable measures of biological age acceleration and may offer additional insights into health outcomes. …”
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Prognostic significance of calcium-related genes in lung adenocarcinoma and the role of TNNC1 in macrophage polarization and erlotinib resistance by Jian Feng, Zhe Chen, Gaoming Wang, Yu Yao, Xuewen Min, Jing Luo, Kai Xie

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The role of technical chart patterns in the early Bitcoin market: intraday evidence from the Mt.Gox transaction dataset by Kevin Rink

“…Employing a pattern recognition algorithm, we identify hourly trading signals for five major chart patterns. …”
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Integrating bioinformatics and machine learning to elucidate the role of protein glycosylation-related genes in the pathogenesis of diabetic kidney disease. by Ziyang Liu, Zengyuan Qin, Wenxin Bai, Shasha Wang, Chunling Huang, Na Li, Lei Yan, Yue Gu, Fengmin Shao

“…This study aimed to investigate the role of protein glycosylation in DKD pathogenesis and its association with gene expression changes, with the goal of identifying diagnostic biomarkers and personalized therapeutic targets.…”
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The joint role of the immune microenvironment and N7-methylguanosine for prognosis prediction and targeted therapy in acute myeloid leukemia by Zhixiang Chen, Zhixiang Chen, Zhimei Chen, Xiaobo Huang, Xiaobo Huang, Xiaobo Huang, Xiongbin Yan, Xiongbin Yan, Xiaolin Lai, Xiaolin Lai, Shaoyuan Wang, Shaoyuan Wang

“…This study aims to establish an IME-related and m7G-related prognostic model for improved risk stratification and personalized treatment in AML.MethodsImmune score for the Cancer Genome Atlas acute myeloid leukemia (AML) patients were calculated using the ESTIMATE algorithm, followed by identification of immune score-associated differentially expressed genes Non-negative matrix factorization (NMF) clustering was performed to stratify AML subtypes based on immune microenvironment (immune microenvironment)-related DEGs and 29 m7G regulatory genes. …”
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Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation by Jingyi Hou, Jingyi Hou, Jingyi Hou, Lihan Wang, Lihan Wang, Naiqiang Zhu, Xueli Li

“…A protein-protein interaction (PPI) network of mitoDEGs was constructed, and hub mitoDEGs associated with MI were identified using CytoHubba and molecular complex detection (MCODE) algorithms. …”
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Exploring the link between the ZJU index and sarcopenia in adults aged 20–59 using NHANES and machine learning by Huan Chen, Ning Du, Hong Xiao, Zhao Wang

“…To improve risk stratification and identify key predictors, machine learning techniques—including Random Forest, SHAP, and the Boruta algorithm—were applied. Each standard deviation increase in ZJU was associated with an 13% higher likelihood of sarcopenia [OR = 1.13, 95% CI 1.08–1.17]. …”
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Psychometric Properties and the Network Analysis of the Turkish Version of the Multidimensional Flourishing Scale: Associations with Psychological Distress by İbrahim Dadandı, Fatih Aydın

“…In recent years, the role of flourishing in mental health has gained growing recognition, making the establishment of psychometrically and culturally validated instruments crucial for advancing theory and practice. …”
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Extreme Mediterranean cyclones and associated variables in an atmosphere-only vs. an ocean-coupled regional model by M. Chericoni, M. Chericoni, M. Chericoni, G. Fosser, E. Flaounas, G. Sannino, G. Sannino, A. Anav, A. Anav

“…<p>Complex air–sea interactions play a major role in both the variability and the extremes of the Mediterranean climate. …”
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Integrative analysis of T cell-associated markers in Ewing sarcoma reveals prognostic signatures and immune dynamics by Umair Ali Khan Saddozai, Umair Ali Khan Saddozai, Chenxu Liu, Chenxu Liu, Fei Yan, Zhendong Lu, Muhammad Babar Khawar, Muhammad Babar Khawar, Muhammad Usman Akbar, Saadullah Khattak, Haibo Sun, Haibo Sun, Ping Yang

“…Immune infiltration was assessed using the CIBERSORT algorithm.ResultsT cell marker analyses revealed key roles in pathways such as PI3K-Akt signaling and immune modulation. …”
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Investigating the Prognostic Role of Telomerase-Related Cellular Senescence Gene Signatures in Breast Cancer Using Machine Learning by Qiong Li, Hongde Liu

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Transforming Sleep Monitoring: Review of Wearable and Remote Devices Advancing Home Polysomnography and Their Role in Predicting Neurological Disorders by Diana Vitazkova, Helena Kosnacova, Daniela Turonova, Erik Foltan, Martin Jagelka, Martin Berki, Michal Micjan, Ondrej Kokavec, Filip Gerhat, Erik Vavrinsky

“…The paper highlights the integration of hardware innovations, targeted sleep parameters, and partially advanced algorithms, illustrating how these elements converge to provide reliable sleep health information. …”
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Using machine learning methods to investigate the role of volatile organic compounds in non-alcoholic fatty liver disease by Chih-Hao Shen, Ruei-Hao Huang, Yaw-Kuen Li, Ta-Wei Chu, Ta-Wei Chu, Dee Pei, Dee Pei

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“Dictionary of immune responses” reveals the critical role of monocytes and the core target IRF7 in intervertebral disc degeneration by Peichuan Xu, Peichuan Xu, Kaihui Li, Jinghong Yuan, Jinghong Yuan, Jiangminghao Zhao, Jiangminghao Zhao, Huajun Pan, Huajun Pan, Chongzhi Pan, Chongzhi Pan, Wei Xiong, Wei Xiong, Jianye Tan, Jianye Tan, Tao Li, Tao Li, Guanfeng Huang, Guanfeng Huang, Xiaolong Chen, Xiaolong Chen, Xinxin Miao, Dingwen He, Xigao Cheng, Xigao Cheng

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TMEM132A: a novel susceptibility gene for lung adenocarcinoma combined with venous thromboembolism identified through comprehensive bioinformatic analysis by Pei Xie, Yingli Liu, Pingping Bai, Yue Ming, Qi Zheng, Li Zhu, Yong Qi

“…Molecular crosstalk analysis identified candidate genes through differential expression algorithms and disease-association metrics. Functional annotation employed GO and KEGG analyses to elucidate the biological significance of identified CGs. …”
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ProstaNet: A Novel Geometric Vector Perceptrons–Graph Neural Network Algorithm for Protein Stability Prediction in Single- and Multiple-Point Mutations with Experimental Validation... by Tianjian Liang, Ze-Yu Sun, Rieko Ishima, Xiang-Qun Xie, Ying Xue, Wei Li, Zhiwei Feng

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