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Arterial Multi-Path Green Wave Control Model Concurrently Considering Motor Vehicles and Electric Bicycles
Published 2024-11-01Get full text
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CNN-Transformer-BiGRU: A Pump Fault Detection Model for Industrialized Recirculating Aquaculture Systems
Published 2025-05-01Get full text
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VDMS: An Improved Vision Transformer-Based Model for PM<sub>2.5</sub> Concentration Prediction
Published 2025-06-01Get full text
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TransBind allows precise detection of DNA-binding proteins and residues using language models and deep learning
Published 2025-04-01“…To address these challenges, we introduce TransBind, an alignment-free deep learning framework that predicts DNA-binding proteins and residues directly from a single primary sequence, eliminating the need for MSAs. By leveraging features from pre-trained protein language models, TransBind effectively handles the issue of data imbalance and achieves superior performance. …”
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Uncovering Social States in Healthy and Clinical Populations Using Digital Phenotyping and Hidden Markov Models: Observational Study
Published 2025-04-01“…We trained the HMM on a subset of HCs (91/348, 26.1%) and selected a model with socially active and inactive states. Then, we generated hidden state sequences per participant and calculated their “total dwell time,” that is, the percentage of time spent in the socially active state. …”
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Mutations in hnRNP A1 drive neurodegeneration and alternative RNA splicing of neuronal gene targets
Published 2025-03-01“…Herein, we utilized a novel, neuron-specific model of neurodegeneration by transducing primary mouse neurons with mutant forms of the RNA binding protein heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) identified from MS patients, including one within the M9-nuclear localization sequence of hnRNP A1 (A1(P275S)) and a second in the prion-like domain of hnRNP A1 (A1(F263S)) to test the hypothesis that neuronal hnRNP A1 dysfunction drives neurodegeneration in MS.Examination of hnRNP A1 localization in neurons revealed an increase in nucleocytoplasmic mislocalization in neurons transduced with A1(P275S), but not A1(F263S). …”
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Interpretability Study of Gradient Information in Individual Travel Prediction
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A Deep Learning-Based Approach for Predicting Michaelis Constants from Enzymatic Reactions
Published 2025-04-01Get full text
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Named Entity Recognition in Online Medical Consultation Using Deep Learning
Published 2025-03-01Get full text
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