Deep Thought on the HIV Cured Cases: Where Have We Been and What Lies Ahead? by Qing Xiao, Sanxiu He, Chaoyu Wang, Yixing Zhou, Chensi Zeng, Jun Liu, Tingting Liu, Tingting Li, Xi Quan, Linyue Wang, Liuyue Zhai, Yi Liu, Jun Li, Xiaomei Zhang, Yao Liu

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The impact of Immunomodulators on Reactivity the immune System cells in Model Vaccinal process against Tularemia by A. L. Kravtsov, S. N. Klyueva, S. A. Bugorkova

“…Additionally, for the characterization of changes in the functional status of lymphocytes nuclei the light microscopy was used and titers of specific antibodies were determined. …”
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Benign essential blepharospasm: epidemiology, clinical manifestations, pathophysiology, botulinum toxin therapy by Z. A. Zalyalova

“…Botulinum toxin therapy is the most effective treatment for BPS. The advantage of Xeomin® that does not contain complexing proteins, is characterized by a low probability of antibody production, is the ability to vary between-injection intervals. …”
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Assessing the Influence of Selected Permeabilization Methods on Lymphocyte Single-Cell Multi-Omics by Shifan Ding, Na Lu, Hassan Abolhassani

“…(1) Background: Single-cell multi-omics is a powerful method for the dissection and detection of complicated immunologic functions and synapses. However, most currently available technologies merge datasets of different omics from separate portions of the same sample to generate combined multi-omics. …”
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Engineering Stepped Structures on Hydroxyapatite Surfaces: A Potential Strategy to Modulate Bone Marrow Mesenchymal Stem Adhesion, Spreading, and Proliferation by Yongmei Wang, Fang Wang, Min Gong, Lidan Chen, Yun Wang, Pu Xu, Zhu Zeng, Zuquan Hu, Jin Chen

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Virus-Mimicking Polymer Nanocomplexes Co-Assembling HCV E1E2 and Core Proteins with TLR 7/8 Agonist—Synthesis, Characterization, and In Vivo Activity by Thomas R. Fuerst, Alexander Marin, Sarah Jeong, Liudmila Kulakova, Raman Hlushko, Katrina Gorga, Eric A. Toth, Nevil J. Singh, Alexander K. Andrianov

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The Role of Glutamine in the Prevention of Ultraviolet-C-Induced Platelet Activation by Mazhar Mushtaq, Uh-Hyun Kim

“…However, its deleterious effect remains, such as the activation of platelets, thus causing the platelets to lose their physiological function. …”
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LPS promotes the production of ROS in neutrophils to regulate their killing activity against Mycobacterium tuberculosis by Lina Jiang, Zhenxing Su, Yangxiao Zhang, Hongsheng Liu, Hongtao Wang

“…We investigated the killing function of neutrophils against Mycobacterium tuberculosis (M.tb) and the effect of neutrophils activated by lipopolysaccharide (LPS) on the production of reactive oxygen species (ROS), to evaluate the mechanism by which neutrophils eradicate M.tb mediated infection and find theoretical basis for clinical treatment of tuberculosis. …”
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The stability of complement-mediated bactericidal activity in human serum against Salmonella. by Colette M O'Shaughnessy, Adam F Cunningham, Calman A Maclennan

“…Up to three freeze-thaw cycles had no effect on the persistence of bactericidal activity and hemolytic complement assays confirmed no effect on complement function. …”
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Interleukin-1 Modulation of Human Placental Trophoblast Proliferation by Athip Nilkaeo, Suthinee Bhuvanath

“…Yet, its biological function on placental cells is not well defined. In this study, we employed JAR choriocarcinoma cell line as a model of human placental trophoblast to study the effect of IL-1. …”
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CircMORC1 downregulated in plasma EVs promotes gastric cancer cell proliferation and invasion via miR-103a-1-5p sponging by Xiang-Ming Zhai, Yi-Qi Yang, Li Lin, Huan-Chang Luo, Zhi-Wei Guo, Ying-Song Wu

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Analysis of the application of different plasmapheresis modes in immune diseases and acute rejection of kidney transplantation by ZHAO Yan, LEI Jie, LI Su-tong, DAI Wei

“…Conclusions Selective double filtration plasmapheresis is performed in patients with immune diseases and acute rejection of renal transplantation, which can effectively improve the level of immunoglobulin IgG and anti-GBM antibody, shorten the treatment time, improve the effective rate of treatment and reduce the adverse reactions. …”
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Inhibition of FAM19A5 reverses synaptic loss and cognitive decline in mouse models of Alzheimer’s disease by Han-Byul Kim, Sangjin Yoo, Hoyun Kwak, Shi-Xun Ma, Ryunhee Kim, Minhyeok Lee, Nui Ha, Soonil Pyo, Soon-Gu Kwon, Eun-Ho Cho, Sang-Myeong Lee, Juwon Jang, Won Kyum Kim, Hae-Chul Park, Minkyung Baek, Yosub Park, Ji-Young Park, Jin-Woo Park, Sun Wook Hwang, Jong-Ik Hwang, Jae Young Seong

“…NS101 treatment enhanced the frequency of mEPSCs and fEPSPs in the hippocampal synapses of APP/PS1 mice, leading to improved cognitive function. The increases in plasma FAM19A5 levels upon systemic NS101 administration suggest that the antibody effectively engages its target and facilitates the transport of FAM19A5 from the brain. …”
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CLINICAL LABORATORY INDICATORS OF PREGNANT WITH ANTIPHOSPHOLIPID SYNDROME IN COMPLEX THERAPY WITH USING INTRAVENOUS IMMUNOGLOBULIN by V. I. Linnikov

“…It is noted that immune-modulating effect is probably related to its positive impact on the function of T-regulatory lymphocytes.…”
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Toggle switch residues control allosteric transitions in bacterial adhesins by participating in a concerted repacking of the protein core. by Dagmara I Kisiela, Pearl Magala, Gianluca Interlandi, Laura A Carlucci, Angelo Ramos, Veronika Tchesnokova, Benjamin Basanta, Vladimir Yarov-Yarovoy, Hovhannes Avagyan, Anahit Hovhannisyan, Wendy E Thomas, Ronald E Stenkamp, Rachel E Klevit, Evgeni V Sokurenko

“…Our study shows that allosteric transitions in bacterial adhesins depend on toggle switch residues and that an antibody that blocks the switch effectively disables adhesive protein function.…”
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Severe Hypocalcemia and Dramatic Increase in Parathyroid Hormone after Denosumab in a Dialysis Patient: A Case Report and Review of the Literature by Ravinder D. Bhanot, Jasleen Kaur, Zeenat Bhat

“…Denosumab, an injectable human monoclonal antibody with affinity for nuclear factor-kappa ligand (RANKL), is an effective treatment for osteoporosis in postmenopausal women and men. …”
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Acinar Cell Proliferation Promoted by BMP2 in Injured Mouse Parotid Gland: BMP2 Promotes Cell Proliferation in Parotid Gland by Megumi Yokoyama, Osamu Katsumata-Kato, Junko Fujita-Yoshigaki

“…To identify factors that affect salivary gland recovery, we investigated the expression and function of bone morphogenetic protein 2 (BMP2) in mice. …”
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Lactobacillus plantarum-derived extracellular vesicles from dietary barley leaf supplementation attenuate Citrobacter rodentium infection and intestinal inflammation by Yu Feng, Qian Zhao, Yifan Zhao, Chen Ma, Meiling Tian, Xiaosong Hu, Fang Chen, Daotong Li

“…Results BL ameliorated the severity of C. rodentium-induced colitis, and this effect was linked to improved gut homeostasis and enhanced mucosal barrier function. …”
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High expression of long non-coding RNA ZEB1-AS1 promotes colorectal cancer cell proliferation partially by suppressing p15 expression by Huangbo Gong, Hao Wen, Xuhui Zhu, Yifan Lian, Xiaojun Yang, Zhuyin Qian, Jin Zhu

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Coagulation and thyroiditis are factors associated with adverse pathological features in differentiated thyroid cancer: a retrospective cohort study by Xiao Chen, Han-yu Wang, Lu Yu, Jia-qi Liu, Hui Sun

“…PC0 is mainly composed of prothrombin time and international normalized ratio, and the score represents better coagulation function and has a protective effect on LNM. PC1 is mainly composed of thyroid peroxidase antibody and thyroid texture, and the score represents the severity of thyroiditis and has a protective effect on LNM and CI. …”
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