Long COVID-19 autoantibodies and their potential effect on fertility by Laura Talamini, Dennyson Leandro M. Fonseca, Darja Kanduc, Olivier Chaloin, Cindy Verdot, Christian Galmiche, Arad Dotan, Igor Salerno Filgueiras, Maria Orietta Borghi, Maria Orietta Borghi, Pier Luigi Meroni, Natalia Y. Gavrilova, Varvara A. Ryabkova, Varvara A. Ryabkova, Leonid P. Churilov, Leonid P. Churilov, Gilad Halpert, Gilad Halpert, Christian Lensch, Lorenz Thurner, Siew-Wai Fong, Lisa F.P. Ng, Laurent Rénia, Laurent Rénia, Laurent Rénia, Barnaby E. Young, Barnaby E. Young, Barnaby E. Young, David Chien Lye, David Chien Lye, David Chien Lye, David Chien Lye, José Manuel Lozano, Otávio Cabral-Marques, Otávio Cabral-Marques, Otávio Cabral-Marques, Otávio Cabral-Marques, Otávio Cabral-Marques, Otávio Cabral-Marques, Otávio Cabral-Marques, Yehuda Shoenfeld, Yehuda Shoenfeld, Sylviane Muller, Sylviane Muller

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SGLT2 inhibitors in lupus nephritis: a multicentric study in Latin America by José L. Daza, Gerardo Gutiérrez, Rosa L. Peñuela-Murcia, Andrés Cárdenas, Juan S. Reyes-Bello

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An Attomolar-Level Optical Device for Monitoring Receptor–Analyte Interactions Without Functionalization Steps: A Case Study of Cytokine Detection by Nunzio Cennamo, Francesco Arcadio, Chiara Marzano, Rosalba Pitruzzella, Mimimorena Seggio, Maria Pesavento, Stefano Toldo, Antonio Abbate, Luigi Zeni

“…Three interleukins, IL-1β, IL-17A, and IL-18, were detected in the attomolar concentrations range by monitoring the resonance wavelength shift over time due to the cytokine/antibody (protein–protein) interaction. The POF-based device was proven to be effective for detecting several interleukins at the attomolar level in a few minutes and without functionalization processes.…”
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Immunotropic Properties of Anaferon and Anaferon Pediatric by E. S. Zhavbert, Yu. L. Dugina, O. I. Epstein

“…The crucial mechanism of the immunotropic action of R-A antibodies to INF-γ was the effect on the system of interferons and in particular on INF-γ and functionally conjugated cytokines, resulting in normalization of the functional activity of the innate factors of the immune defense and increasing of the antiviral action. …”
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Detection of HPV-16 L1 antigen using MoS2 nanosheets and amine-functionalized copper doped carbon dots by Rajmohan Swetha, Karutha Pandian Divya, Lakshmi Devi A, T.G. Satheesh Babu

“…The present work deals with the development of a label-free electrochemical immunosensor by modification of electrode surface using 2D MoS2 nanosheets and amine functionalized copper doped carbon dots (f-CuCD). The copper doped carbon dot with high surface area 2D material like MoS2 provides a stable platform for the immobilization of antibody which aids in the sensor performance. …”
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Role of receptor activity modifying protein 1 in function of the calcium sensing receptor in the human TT thyroid carcinoma cell line. by Aditya J Desai, David J Roberts, Gareth O Richards, Timothy M Skerry

“…Blockade of RAMP1 using specific antibodies induced a concentration-dependent reduction in CaSR-mediated signalling in response to Cinacalcet in TT cells, suggesting a novel functional role for RAMP1 in regulation of CaSR signalling in addition to its known role in receptor trafficking. …”
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Carbon-Encapsulated Iron Nanoparticles Seeking Integrins in Murine Glioma by Stawarska A, Bamburowicz-Klimkowska M, Bystrzejewski M, Kasprzak A, Grudzinski IP

“…Relaxometry measurements were performed with a 1.5 T (63 MHz) MRI scanner using both GL261 cells and C57BL/6 mice bearing GL261 tumors.Results: The results showed that Fe@C-CONH-anti-CD61 and Fe@C-(CH2)2-CONH-anti-CD61 nanoparticles have higher binding affinity towards GL261 cells compared to pristine nanoparticles without antibodies. Studies evidenced that the antibody-decorated nanoparticles did not produce any severe cytotoxic effects on murine glioma cells. …”
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Improved Myocardial Function in Autoimmune-Mediated Fetal Complete Atrioventricular Block Following Dexamethasone and Intravenous Immunoglobulin: A Case Report by Maria Elisa Martini Albrecht, Milena Giuberti Bathomarco, Gustavo Yano Callado, Nathalie Jeanne Bravo-Valenzuela, Edward Araujo Júnior

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Nanobodies and their derivatives: pioneering the future of cancer immunotherapy by Haixia Li, Quan Zhou, Nan Cao, Chenghao Hu, Jincheng Wang, Yu He, Shan Jiang, Qi Li, Miao Chen, Li Gong, Ming Luo, Xinzhou Deng, Zhiguo Luo

“…In addition to their small size (~ 15 kDa), nanobodies possess a range of advantageous properties, including high stability, strong specificity and affinity for target antigens, low immunogenicity, and cost-effective production. Nonetheless, their short serum half-life and lack of Fc-mediated functions may limit efficacy, which can be addressed by Fc fusion, albumin binding, or multivalent construct design. …”
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Enhancement of immunogenicity of SARS-CoV-2 spike protein expressed in Escherichia coli by fusion of the CRM197 functional domain by Xibing Yu, Yinmeng Yang, Yinmeng Yang, Miao Zhang, Miao Zhang, Qiantong Shen, Qiantong Shen, Yun Zhu, Yun Zhu, Tong An, Tong An, Siqi Li, Siqi Li, Kexin Zhang, Kexin Zhang, Shuaiyao Lu, Shaohong Lu, Shaohong Lu, Fangcheng Zhuang, Fangcheng Zhuang, Meng Gao, Meng Gao

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Effects of environmental pollutant exposure on the development of immune system in children by HUO Xia, XIE Bo, ZENG Zhijun, XU Xijin

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Impact of innate lymphoid cell type 2 in chronic lymphocytic leukemia on the function of treg and CD8+ T cells through IL-9 by Ruixue Yang, Xuejiao Zeng, Xierenguli Alimu, Jianhua Qu

“…Abstract Objective This study investigated the impact of innate lymphoid cell type 2 (ILC2s) on the function of regulatory T cells (Treg) and CD8+ T cells in chronic lymphocytic leukemia (CLL) through IL-9. …”
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The development of murine bone marrow-derived mast cells expressing functional human MRGPRX2 for ex vivo and in vivo studies by Maram Bawazir, Maram Bawazir, Saptarshi Roy, Hydar Ali

“…Cell surface MRGPRX2 expression was determined by flow cytometry. Effects of substance P (SP) and LL-37 on Ca2+ mobilization, degranulation and TNF-α generation were determined. …”
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A Luciferase-Based Approach for Functional Screening of 5′ and 3′ Untranslated Regions of the mRNA Component for mRNA Vaccines by Maria Rubtsova, Yuliana Mokrushina, Dmitry Andreev, Maria Poteshnova, Nikita Shepelev, Mariya Koryagina, Ekaterina Moiseeva, Diana Malabuiok, Yury Prokopenko, Stanislav Terekhov, Aleksander Chernov, Elena Vodovozova, Ivan Smirnov, Olga Dontsova, Alexander Gabibov, Yury Rubtsov

“…A combination of the most effective UTRs was used to generate a prototype of an mRNA vaccine capable of inducing neutralizing antibodies against coronavirus. …”
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Growth Arrest-Specific 6 Enhances the Suppressive Function of CD4+CD25+ Regulatory T Cells Mainly through Axl Receptor by Guang-ju Zhao, Jia-yi Zheng, Jia-lan Bian, Long-wang Chen, Ning Dong, Yan Yu, Guang-liang Hong, Arvine Chandoo, Yong-Ming Yao, Zhong-qiu Lu

“…Conclusion. Gas6 has a direct effect on the functions of CD4+CD25+Tregs mainly through its interaction with Axl receptor.…”
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Regulatory Effect of Cinnamaldehyde on Monocyte/Macrophage-Mediated Inflammatory Responses by Byung Hun Kim, Yong Gyu Lee, Jaehwi Lee, Joo Young Lee, Jae Youl Cho

“…Cinnamaldehyde (CA) has been known to exhibit anti-inflammatory and anticancer effects. Although numerous pharmacological effects have been demonstrated, regulatory effect of CA on the functional activation of monocytes and macrophages has not been fully elucidated yet. …”
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Daratumumab treatment for kidney-involved light chain deposition disease prevents renal function progression: a case report with 3 years of follow-up and review of the literature by Xueying Chen, Jie Sun, Pingyan Shen, Zijin Chen, Wen Zhang

“…After the daratumumab treatment, the hematologic response continued progressing to a complete response without any adverse effects and continuous renal function improvement at a low serum free light chain (sFLC) level. …”
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Research status of subclinical hypothyroidism promoting the development and progression of cardiovascular diseases by Peijie Wang, Weiming Zhang, Haiyan Liu, Haiyan Liu

“…Evidence suggests SCH may exacerbate atherosclerosis and cardiac dysfunction through mechanisms such as increased LDL synthesis, oxidative stress, and impaired vascular endothelial function. However, the causal link between SCH and cardiovascular outcomes remains unclear due to study design heterogeneity and overreliance on TSH levels. …”
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Mapping autoantibody targets of full-length C-reactive protein in systemic lupus erythematosus: importance for neutrophil function and classical complement activation by Jesper Karlsson, Lina Wirestam, Hanna Duàn, Suhana Ahmad, Daniel Appelgren, Helena Enocsson, Jonas Wetterö, Christopher Sjöwall

“…The purpose of this study was to investigate binding sites of IgG autoantibodies on the full linear sequence of CRP and identify potential associations with clinical variables in well-characterized SLE patients; a secondary aim was to investigate the effect of an epitope-based synthesized peptide motif on neutrophil functions. …”
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Systematic computer analysis of published literature on nutritional support for vaccination by A. G. Chuchalin, I. Yu. Torshin, O. A. Gromova

“…Clinical studies showed that the support of vaccination with the specified micronutrients not only increases the titre of the respective antibodies to viral and bacterial pathogens but can also prevent unfavorable effects from vaccination. …”
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