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Evaluating platelet concentrates by platelet indices, thromboelastography, and flow cytometry
Published 2024-12-01“…Platelet function (platelet activation and aggregation) was assessed using flow cytometry and compared with freshly prepared PRP. …”
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Antibacterial effects of platelets on five common pathogenic bacteria: a comparative analysis
Published 2025-06-01“…The supernatant protein of platelets co-cultured with MRSA was collected for quantitative proteomics analysis to explore the important antibacterial proteins of platelets. …”
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Influence of flavonoids’ lipophilicity on platelet aggregation
Published 2019-12-01“…As determined by flow cytometry, the exposition of receptors necessary for the promotion of platelet activation and primary clot formation was diminished, i.e., lowered expression of the activated form of integrin αIIbβ3 was observed in the presence of flavanone. …”
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Valsartan effects on platelet activity in patients with arterial hypertension and metabolic syndrom
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Conjoint analysis of methylation, transcriptomic, and proteomic profiles in pemphigus vulgaris
Published 2024-11-01“…Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis highlighted notable pathway abnormalities, including those related to platelet activation, focal adhesions, tight junctions, and infectious inflammatory responses. …”
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Clinical Values of Serum Platelet-Activating Factor in Hypertensive Disorders Complicating Pregnancy
Published 2025-01-01“… Introduction: Serum platelet-activating factor (PAF) was proven to be associated with gestational hypertension. …”
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Macrophage Derived Platelet Activating Factor Implicated in the Resolution Phase of Gouty Inflammation
Published 2014-01-01“…Analysis of sunatants from in vitro differentiated macrophages stimulated with MSU crystals revealed the secretion of platelet activating factor (PAF) 1.54±0.10 mean ± SEM; ng/mL per 106 cells. …”
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Elevated levels of platelet-activating factor and syndecan-1 in severe dengue infections
Published 2025-06-01“…Background: Severe dengue is a serious infection associated with cytokine storms.Objectives: This study investigated the roles of platelet-activating factor (PAF), syndecan-1, and matrix metalloprotein-9 (MMP-9) in dengue severity. …”
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Spontaneous and Induced Platelet Aggregation during Pregnancy and Labor
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Evaluation of antimicrobial activity of platelet-rich fibrin and titanium platelet-rich fibrin with and without incorporation of antibiotics on Porphyromonas gingivalis and Aggrega...
Published 2024-09-01“…The data were subjected to independent t-test, Tukey post hoc test, repeated analysis of variance (ANOVA), and ANOVA. Results: All individual parameters were compared for antimicrobial activity on both bacteria on all 4 days. …”
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Platelets in preeclampsia: an observational study of indices associated with aspirin nonresponsiveness, activation and transcriptional landscape
Published 2025-06-01“…We observed significantly greater expression of CD62P in the placental villous and CD42b in the decidua of the preeclamptic group than in those of the nonpreeclamptic group. Colocalization analysis of CD42b and CD62P revealed that the preeclamptic placenta and decidua presented significant platelet activation. …”
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Modulation of Tumor-Associated Macrophages (TAM) Phenotype by Platelet-Activating Factor (PAF) Receptor
Published 2017-01-01“…Platelet-activating factor (PAF) plays an important role in the pathogenesis of several types of tumors. …”
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Nonlinear association between platelet to albumin ratio and disease activity in patients with early rheumatoid arthritis
Published 2024-11-01“…Abstract The relationship between the platelet to albumin ratio (PAR) and the disease activity of early rheumatoid arthritis (ERA) remains to be elucidated. …”
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Study of platelet activation, hypercoagulable state, and pulmonary hypertension in patients with transfusion-dependent beta-thalassemia
Published 2024-12-01“…CONCLUSIONS: Transfusion-dependent thalassemia is characterized by severe anemia and splenomegaly, leading to complex hemodynamic changes with evidence of platelet activation, hypercoagulable state, liver injury, and increased atherosclerosis. …”
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Acrylamide and bisphenol A: two plastic additives increase platelet activation, via oxidative stress
Published 2025-04-01“…While their presence as environmental pollutants is well known, their specific impact on platelet function and the associated cardiovascular risks remains poorly understood.MethodsTo explore how AA and BPA affect platelet physiology, we performed in vitro assays to assess platelet activation and aggregation following exposure to these compounds. …”
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Interaction of Manganese-Doped Copper Oxide Nano-Platelets with Cells: Biocompatibility and Anticancer Activity Assessment
Published 2025-03-01“…The findings indicate that nano-platelets interact with cells actively by mediating essential molecular processes. …”
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Anti-bacterial activity of dermcidin in human platelets: suppression of methicillin-resistant Staphylococcus aureus growth
Published 2025-07-01“…To further explore the platelet antibacterial mechanism, supernatants from co-culture of platelets and MRSA in vitro were used for proteomic analysis. …”
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Comparasion Between Mitotic Activity, Ki-67 Index and Platelet Volume Index as a Prognostic Marker in Gliablastomas
Published 2019-08-01“…Activity of the tumor microcirculation resulting in platelet activation and release of several cytokines and factors from activated platelets has been suggested to play an active role in neuro-inflammation. …”
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Alterations in Platelet Activity and Elastic Modulus of Healthy Subjects, Carriers of G20210A Polymorphism in the Prothrombin Gene
Published 2016-09-01“…Platelet activation is a complex process in which platelet reorganization takes place associated with changes in the cell shape, topology, membrane elasticity and microparticle production. …”
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