Cloning, expression of carboxylesterase BioH and improvement of its hydrolysis activity by directed evolution by XU Hongna, YU Hongwei

“…Sequence detection showed that the mutation rate was kept as 23 changed bases in each gene on average. In each round of directed evolution, a library with 5 000-6 000 mutants was screened. …”
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Feature Engineering for the Prediction of Scoliosis in 5q‐Spinal Muscular Atrophy by Tu‐Lan Vu‐Han, Vikram Sunkara, Rodrigo Bermudez‐Schettino, Jakob Schwechten, Robin Runge, Carsten Perka, Tobias Winkler, Sebastian Pokutta, Claudia Weiß, Matthias Pumberger

“…These features were validated using expert domain knowledge and used to train a Random Forest Classifier with an observed accuracy of 0.82 and an average receiver operating characteristic (ROC) area of 0.87. …”
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Performance Assessment of an Electrostatic Filter-Diverter Stent Cerebrovascular Protection Device: Evaluation of a Range of Potential Electrostatic Fields Focusing on Small Partic... by Beatriz Eguzkitza, José A. Navia, Guillaume Houzeaux, Constantine Butakoff, Mariano Vázquez

“…The first stage of the work evaluates a variety of strut thicknesses and inter-strut spacings, contrasting with the device-free baseline geometry. The analysis is carried out by imposing flow rate waveforms characteristic of healthy and AF patients. …”
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Impact of Blood Metabolic Profile and Ingestive Behaviours Registered with Noseband Sensor on Methane Emission During Transition Period in Dairy Cows by Justina Krištolaitytė, Karina Džermeikaitė, Arūnas Rutkauskas, Greta Šertvytytė, Gabija Lembovičiūtė, Samanta Arlauskaitė, Akvilė Girdauskaitė, Violeta Juškienė, Remigijus Juška, Walter Baumgartner, Ramūnas Antanaitis

“…Cows were retrospectively classified into low, medium, and high rumination groups according to their average daily rumination duration to investigate the effects of behavioural influences. …”
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Dual-mulching under no-tillage promotes maize root growth and improves yield by optimizing soil hydrothermal conditions in semi-arid regions by Jia Wang, Jun Fan, Huan Wang, Xi Wang, Yuzhu Xing, Yongquan Gao, Mingde Hao

“…The results revealed that NTSP significantly increased soil temperature at the 0–15 cm depth during the VE stage, while reducing the average soil temperature at the 0–30 cm depth during the V6-R3 stage (P < 0.05). …”
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Utilización de indicadores metabólicos en la valoración de la transferencia de inmunidad pasiva en neonatos bovinos Assessment of the passive transference of immunity in calves thr... by Angie Fairut Carrillo, Valentina Loaiza, Rómulo Campos Gaona

“…Average values, higher than 4.5 g/dl of the TSP were found which may indicate that the calves developed passive immunity through colostrums&rsquo; consumption. …”
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Integration of a medication reminder app into the RABBIT-SpA disease registry to record patient data on daily drug usage by Regierer, Anne C., Reich, Andreas, Weiß, Anja, Feuchtenberger, Martin, Zinke, Silke, Lorenz, Hanns-Martin, Syrbe, Uta, Böhm, Peter, Wiegand, Julius, Strangfeld, Anja, Poddubnyy, Denis, Baraliakos, Xenofon

“…The main research question of this preliminary analysis is the concordance between the anti-rheumatic medication documented by the patient via the app and by the rheumatologist via the registry. …”
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Exploring the capabilities of GenAI for oral cancer consultations in remote consultations by Yu-Tao Xiong, Hao-Nan Liu, Yu-Min Zeng, Zheng-Zhe Zhan, Wei Liu, Yuan-Chen Wang, Wei Tang, Chang Liu

“…GPT-3.5-Turbo demonstrated an overall accuracy rate of 77.50% in qualitative analysis, and GPT-4o was 88.20%. The average scores of GPT-3.5Turbo and GPT-4o were 3.96 and 4.35, respectively, with statistically significant differences. …”
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Association of the newly proposed dietary index for gut microbiota and all-cause and cardiovascular mortality among individuals with diabetes and prediabetes by Wenjing Song, Daoqin Liu, Zihe Xing, Luqing Jiang, Yu Tang, Zichen Xu, Lei Li, Shuai Yan, Xia Fu, Yuping Wang, Qiwen Wu

“…The Beneficial Gut Microbiota Score (BGMS) exhibited inverse associations with mortality risks, while the Unfavorable Gut Microbiota Score (UGMS) showed no significant relationship. In the sensitive analysis, the robustness of multiple interpolation results was verified by deleting missing data.ConclusionAmong patients with diabetes or prediabetes, elevated DI-GM levels were negatively correlated with all-cause mortality and cardiovascular mortality risks.…”
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Significant differences in knee kinematics of healthy subjects with high and low anterior tibial laxity by Shiyang Chen, Shaohua Chen, Qingyang Kang, Fangzheng Lin, Fangzheng Lin, Fangzheng Lin, Shuting Zheng, Xixi Liu, Chunhong Guo, Chunhong Guo, Yongjin Li, Yongjin Li, Dingkun Lin, Dingkun Lin, Xiaolong Zeng

“…There were twenty males and fifteen females with an average age of 18.91 ± 0.78 years. Their knees were categorized into “Tight” (the smallest 50%) and “Lax” (the largest 50%) groups based on anterior tibial laxity measurements using a Kneelax3 arthrometer. …”
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Genetic parameters of vulva traits and impact of vulva scores on gilts culling in Large White pigs by J. Zhou, L. Xu, Q. Liu, J. Ma, J. He, D.S. Casey, L. Zhong, G. Su, R. Huang, P. Li, Q. Zhao

“…The average vulva width score of the gilts that were culled due to prolonged oestrus was significantly lower (2.75) compared to that of gilts with normal oestrus (2.90). …”
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Optimising Wastewater Sample Processing for Multiple Pathogen Detection by Miss Shannon Fitz, Debora Akortia, Richard Larbi, Richard Owusu, Gifty Nkrumah, Dr Joyce Akello, Catherine Troman, Dr Jaspreet Mahindroo, Dr Anton Spader, Dr Ben Bellekom, Piya Rajendra, Professor Yaw Adu-Sarkodie, Dr Ellis Owusu-Dabo, Dr Nicholas Grassly, Dr Dilip Abraham, Professor Venkata Raghava Mohan, Dr Michael Owusu, Dr Alex Shaw

“…In London, these methods showed consistent high recovery across pathogens in spiked wastewater with average recovery rates for nOPV2 and typhi of 3.08% and 45.87% (Ceres) and 3.29% and 100% (PEG). …”
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The potential health impact of restricting less-healthy food and beverage advertising on UK television between 05.30 and 21.00 hours: A modelling study. by Oliver T Mytton, Emma Boyland, Jean Adams, Brendan Collins, Martin O'Connell, Simon J Russell, Kate Smith, Rebekah Stroud, Russell M Viner, Linda J Cobiac

“…We estimate that if all HFSS advertising between 05.30 hours and 21.00 hours was withdrawn, UK children (n = 13,729,000), would see on average 1.5 fewer HFSS adverts per day and decrease caloric intake by 9.1 kcal (95% UI 0.5-17.7 kcal), which would reduce the number of children (aged 5-17 years) with obesity by 4.6% (95% UI 1.4%-9.5%) and with overweight (including obesity) by 3.6% (95% UI 1.1%-7.4%) This is equivalent to 40,000 (95% UI 12,000-81,000) fewer UK children with obesity, and 120,000 (95% UI 34,000-240,000) fewer with overweight. …”
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Coeliac plexus radiosurgery for pain management in patients with advanced cancer : study protocol for a phase II clinical trial by Laura A Dawson, Camilla Zimmermann, Aisling Barry, Galia Jacobson, Ronen Fluss, Amira Dany-BenShushan, Talia Golan, Tikva Meron, Marcin Miszczyk, Michael Buckstein, Dayssy Diaz Pardo, Artur Aguiar, Liat Hammer, Adam P Dicker, Maoz Ben-Ailan, Ofir Morag, David Hausner, Zvi Symon, Yaacov R. Lawrence

“…Eligible patients are required to have severe coeliac pain of at least five on the 11-point BPI average pain scale and Eastern Cooperative Oncology Group performance status of two or better. …”
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Combined Application of High-Throughput Sequencing and Metabolomics to Evaluate the Microbial Mechanisms of Plant-Growth-Promoting Bacteria in Enhancing the Remediation of Cd-Conta... by Shan-Shan Gao, Ying-Jun Zhang, Yang Shao, B. Larry Li, Han Liu, Yu-Ying Li, Xue-Min Ren, Zhao-Jin Chen

“…SR-9 implantation modified the composition of the soil bacterial community by increasing the average number of Actinobacteria and <i>Bacillus</i>. …”
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Evaluation of anti-inflammatory properties on the surface of dental implants depending on the type of processing by S. D. Varzhapetian, M. A. Shyshkin, T. V. Strohonova, O. O. Kokar

“…The PEO surface had a monolithic surface layer with rounded pores averaging 4.51 μm2. The DAE surface had a polyhedral irregular shape, about 7–12 μm2. …”
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Aerosols in the Mixed Layer and Mid-Troposphere from Long-Term Data of the Italian Automated Lidar-Ceilometer Network (ALICENET) and Comparison with the ERA5 and CAMS Models by Annachiara Bellini, Henri Diémoz, Gian Paolo Gobbi, Luca Di Liberto, Alessandro Bracci, Francesca Barnaba

“…The seasonal frequency of the EALs reached 40% of the time (Messina-summer), mainly in the 1.5–4.0 km altitude range. An average (wet) PM > 40 μg m⁻³ is associated with the EALs over Rome and Messina. …”
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Uso de Moodle para fortalecer competencias ciudadanas en estudiantes de fisioterapia: un diseño pretest-postest (Use of Moodle to strengthen citizenship competencies in physiother... by Milena Boneth-Collante, Jorge Salazar-Rodríguez, Adriana Angarita-Fonseca

“…The total score per dimension ranged from 0 to 100. Results: The average knowledge score was 60.8 ± 12.9 in the pretest and 65.1 ± 15.4 in the posttest (p = 0.0665). …”
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Addressing Weather Data Gaps in Reference Crop Evapotranspiration Estimation: A Case Study in Guinea-Bissau, West Africa by Gabriel Garbanzo, Jesus Céspedes, Marina Temudo, Tiago B. Ramos, Maria do Rosário Cameira, Luis Santos Pereira, Paula Paredes

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Global burden of low vision and blindness due to age-related macular degeneration from 1990 to 2021 and projections for 2050 by Shiyan Zhang, Jianping Ren, Ruiting Chai, Shuang Yuan, Yinzhu Hao

“…Autoregressive Integrated Moving Average(ARIMA) and Exponential Smoothing(ES) models provided future projections. …”
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